YU44788B - Process for making ready for use solution for injections containing antitumor antracyclic glicoside - Google Patents

Process for making ready for use solution for injections containing antitumor antracyclic glicoside

Info

Publication number
YU44788B
YU44788B YU1035/86A YU103586A YU44788B YU 44788 B YU44788 B YU 44788B YU 1035/86 A YU1035/86 A YU 1035/86A YU 103586 A YU103586 A YU 103586A YU 44788 B YU44788 B YU 44788B
Authority
YU
Yugoslavia
Prior art keywords
glicoside
antracyclic
use solution
injections containing
making ready
Prior art date
Application number
YU1035/86A
Other languages
English (en)
Other versions
YU103586A (en
Inventor
Gaetano Gatti
Diego Oldani
Giuseppe Bottoni
Carlo Confalonieri
Luciano Gambini
Ponti Roberto De
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10583216&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU44788(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Priority to SI8611035A priority Critical patent/SI8611035A8/sl
Publication of YU103586A publication Critical patent/YU103586A/xx
Publication of YU44788B publication Critical patent/YU44788B/xx
Priority to HRP-1035/86A priority patent/HRP920525B1/xx
Priority to BA970187A priority patent/BA97187B1/bs

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
YU1035/86A 1985-08-02 1986-06-16 Process for making ready for use solution for injections containing antitumor antracyclic glicoside YU44788B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
SI8611035A SI8611035A8 (sl) 1985-08-02 1986-06-16 Postopek pripravljanja injekcijske raztopine, pripravljene za uporabo, ki vsebuje protitumorni, antraciklinski glikozid
HRP-1035/86A HRP920525B1 (en) 1985-08-02 1992-09-28 Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
BA970187A BA97187B1 (bs) 1985-08-02 1997-08-14 Postupak za pravljenje rastvora za injekcije spremnog za koriscenje koji sadrzi antitumorni antraciklinski glikozid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858519452A GB8519452D0 (en) 1985-08-02 1985-08-02 Injectable solutions

Publications (2)

Publication Number Publication Date
YU103586A YU103586A (en) 1988-04-30
YU44788B true YU44788B (en) 1991-02-28

Family

ID=10583216

Family Applications (1)

Application Number Title Priority Date Filing Date
YU1035/86A YU44788B (en) 1985-08-02 1986-06-16 Process for making ready for use solution for injections containing antitumor antracyclic glicoside

Country Status (34)

Country Link
US (1) US4946831A (cs)
JP (1) JPH0655667B2 (cs)
KR (1) KR920001773B1 (cs)
CN (1) CN1064531C (cs)
AT (1) AT397463B (cs)
BE (1) BE905202A (cs)
BG (1) BG60425B2 (cs)
CA (1) CA1291037C (cs)
CH (2) CH668911C1 (cs)
CS (1) CS277561B6 (cs)
CY (1) CY1592A (cs)
DE (1) DE3621844C2 (cs)
DK (1) DK167557B1 (cs)
ES (1) ES8801580A1 (cs)
FI (1) FI86800C (cs)
FR (1) FR2585569B1 (cs)
GB (2) GB8519452D0 (cs)
GR (1) GR861556B (cs)
HK (1) HK93990A (cs)
HU (1) HU196123B (cs)
IE (1) IE59297B1 (cs)
IL (1) IL79129A (cs)
IT (1) IT1204906B (cs)
NL (2) NL191507C (cs)
NO (1) NO170913C (cs)
NZ (1) NZ216604A (cs)
PH (1) PH22332A (cs)
PT (1) PT82865B (cs)
RU (2) RU1837883C (cs)
SE (1) SE466383C (cs)
SG (1) SG80690G (cs)
UA (1) UA29383C2 (cs)
YU (1) YU44788B (cs)
ZA (1) ZA864792B (cs)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5124317A (en) 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5977082A (en) * 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124318A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.R.L. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
JP2621255B2 (ja) * 1986-12-05 1997-06-18 フアーミタリア・カルロ・エルバ・ソシエタ・ア・レスポンサビリタ・リミタータ アントラサイクリングリコシド溶液およびその製造方法
FI883338L (fi) * 1987-07-16 1989-01-17 Bristol Myers Co Vattenloesningar av doxorubicinhydroklorid.
FI883337A7 (fi) * 1987-07-16 1989-01-17 Bristol Myers Squibb Co Doksorubisiinihydrokloridin ei-vesiliuoksia
DE3801178A1 (de) * 1988-01-18 1989-07-27 Hoechst Ag Stabilisierte trockenzubereitung zytostatisch wirksamer anthracyclin-antibiotika und verfahren zu ihrer herstellung
DE68905577T2 (de) * 1988-12-05 1993-07-01 Bristol Myers Squibb Co Doxorubicin-loesungen.
FI895733A7 (fi) * 1988-12-05 1990-06-06 Bristol Myers Squibb Co Doksorubisiinin vesiliuoksia
GB9200247D0 (en) * 1992-01-07 1992-02-26 Erba Carlo Spa Pharmaceutical compositions containing polymer derivative-bound anthracycline glycosides and a method for their preparation
DE19544532C2 (de) * 1995-11-29 1997-12-11 Pharma Dynamics Gmbh Verfahren zum Herstellen eines Doxorubicin-Lyophilisats
DE69609845T2 (de) * 1996-12-16 2000-12-21 Pharmachemie B.V., Haarlem Verfahren zur Herstellung von Epirubicin oder Zusatzsalzen davon, von Daunorubicin
EP0954283B1 (en) 1996-12-30 2007-03-21 Battelle Memorial Institute Use of a non-encapsulated anticancer drug for the preparation of a formulation for treating neoplasms by inhalation
US20090253220A1 (en) * 2003-10-28 2009-10-08 Sukanta Banerjee Absorbing Biomolecules into Gel-Shell Beads
TW200718426A (en) * 2005-05-11 2007-05-16 Sicor Inc Stable lyophilized anthracycline glycosides
WO2013063286A1 (en) * 2011-10-25 2013-05-02 Nektar Therapeutics Treatment of patients suffering from cancer
CN102614118B (zh) * 2012-03-15 2014-04-30 北京协和药厂 注射用盐酸表柔比星制剂的制备方法及制剂

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
GB1457632A (en) * 1974-03-22 1976-12-08 Farmaceutici Italia Adriamycins
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates
FR2314726A1 (fr) * 1975-06-16 1977-01-14 Rhone Poulenc Ind Nouveaux derives du naphtagene, leur preparation et les compositions qui les contiennent
GB1511559A (en) * 1975-09-26 1978-05-24 Farmaceutici Italia Anthracycline glycosides
FR2397425A1 (fr) * 1977-07-11 1979-02-09 Rhone Poulenc Ind Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent
DE2738656A1 (de) * 1977-08-26 1979-03-08 Microbial Chem Res Found Anthracyclinglycoside, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4177264A (en) * 1977-10-17 1979-12-04 Sri International N-benzyl anthracyclines
GB2007645B (en) * 1977-10-17 1982-05-12 Stanford Res Inst Int Benzyl anthracyclines and pharmaceutical compositions containing them
FR2430425A1 (fr) * 1978-07-07 1980-02-01 Rhone Poulenc Ind Nouveaux derives de la daunorubicine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2433027A1 (fr) * 1978-08-08 1980-03-07 Rhone Poulenc Ind Nouveau procede de preparation de derives de la doxorubicine
US4325947A (en) * 1981-05-12 1982-04-20 Farmitalia Carlo Erba S.P.A. 4-Demethoxy-4'-deoxydoxorubicin
US4438105A (en) * 1982-04-19 1984-03-20 Farmaitalia Carlo Erba S.P.A 4'-Iododerivatives of anthracycline glycosides
US4464529A (en) * 1982-07-20 1984-08-07 Sri International Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin
JPS6092212A (ja) * 1983-10-26 1985-05-23 Kyowa Hakko Kogyo Co Ltd ドキソルビシン塩の製剤
JP2621255B2 (ja) * 1986-12-05 1997-06-18 フアーミタリア・カルロ・エルバ・ソシエタ・ア・レスポンサビリタ・リミタータ アントラサイクリングリコシド溶液およびその製造方法

Also Published As

Publication number Publication date
AU5885886A (en) 1987-02-12
FI86800C (fi) 1999-10-28
ES8801580A1 (es) 1988-02-16
IT8620917A0 (it) 1986-06-26
KR870001828A (ko) 1987-03-28
KR920001773B1 (ko) 1992-03-02
JPS6248629A (ja) 1987-03-03
NL191507B (nl) 1995-04-18
NO862587L (no) 1987-02-03
DE3621844C2 (de) 1994-02-17
SE466383B (sv) 1992-02-10
CS470886A3 (en) 1992-11-18
IL79129A (en) 1992-03-29
IL79129A0 (en) 1986-09-30
PT82865A (en) 1986-07-01
AU598197B2 (en) 1990-06-21
IT1204906B (it) 1989-03-10
GB8614800D0 (en) 1986-07-23
RU2110263C1 (ru) 1998-05-10
NZ216604A (en) 1989-10-27
FI86800B (fi) 1992-07-15
GB8519452D0 (en) 1985-09-11
GB2178311B (en) 1989-10-11
NO862587D0 (no) 1986-06-26
DE3621844A1 (de) 1987-03-05
ATA176886A (de) 1993-09-15
HK93990A (en) 1990-11-23
ZA864792B (en) 1988-02-24
GR861556B (en) 1986-10-17
UA29383C2 (uk) 2000-11-15
CN1064531C (zh) 2001-04-18
BG60425B2 (bg) 1995-03-31
NL300011I1 (nl) 2000-10-02
DK306286A (da) 1987-02-03
CH668911A5 (de) 1989-02-15
CH668911C1 (de) 2000-05-31
NL191507C (nl) 2000-02-16
DK306286D0 (da) 1986-06-27
NL8601698A (nl) 1987-03-02
SE8602743L (sv) 1987-02-03
RU1837883C (ru) 1993-08-30
GB2178311A (en) 1987-02-11
HUT42326A (en) 1987-07-28
CN86104283A (zh) 1987-01-28
ES556291A0 (es) 1988-02-16
US4946831A (en) 1990-08-07
SG80690G (en) 1990-11-23
AT397463B (de) 1994-04-25
YU103586A (en) 1988-04-30
PH22332A (en) 1988-07-29
NO170913C (no) 2003-10-10
DK167557B1 (da) 1993-11-22
CY1592A (en) 1992-04-03
IE861598L (en) 1987-02-02
CA1291037C (en) 1991-10-22
BE905202A (fr) 1987-02-02
SE466383C (sv) 1996-02-19
HU196123B (en) 1988-10-28
FI862629L (fi) 1987-02-03
JPH0655667B2 (ja) 1994-07-27
FI862629A0 (fi) 1986-06-19
PT82865B (pt) 1989-01-17
IE59297B1 (en) 1994-02-09
FR2585569B1 (fr) 1990-01-19
SE8602743D0 (sv) 1986-06-19
CH690490C2 (de) 2000-09-29
FR2585569A1 (fr) 1987-02-06
CS277561B6 (en) 1993-03-17
NO170913B (no) 1992-09-21

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