FR2433027A1 - Nouveau procede de preparation de derives de la doxorubicine - Google Patents

Nouveau procede de preparation de derives de la doxorubicine

Info

Publication number
FR2433027A1
FR2433027A1 FR7823336A FR7823336A FR2433027A1 FR 2433027 A1 FR2433027 A1 FR 2433027A1 FR 7823336 A FR7823336 A FR 7823336A FR 7823336 A FR7823336 A FR 7823336A FR 2433027 A1 FR2433027 A1 FR 2433027A1
Authority
FR
France
Prior art keywords
acyl
amino
deriv
antitumour
prepn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7823336A
Other languages
English (en)
Other versions
FR2433027B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Priority to FR7823336A priority Critical patent/FR2433027A1/fr
Publication of FR2433027A1 publication Critical patent/FR2433027A1/fr
Application granted granted Critical
Publication of FR2433027B1 publication Critical patent/FR2433027B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procédé de préparation d'un dérivé de la doxorubicine I où R est un radical II où R 1 est H, alcoyle, phényle ou benzyle, R2 est H ou forme avec R1 un radical alcoylène, caractérise en ce que l'on traite un produit III où R3 est un radical IV où les X sont O ou S et sont identiques (les symboles R4 sont alcoyle ou phényle substitué ou forment un alcoylène) ou différents (les symboles R4 forment un alcoylène), par toute méthode connue pour obtenir un alcool à partir d'un ester.
FR7823336A 1978-08-08 1978-08-08 Nouveau procede de preparation de derives de la doxorubicine Granted FR2433027A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7823336A FR2433027A1 (fr) 1978-08-08 1978-08-08 Nouveau procede de preparation de derives de la doxorubicine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7823336A FR2433027A1 (fr) 1978-08-08 1978-08-08 Nouveau procede de preparation de derives de la doxorubicine

Publications (2)

Publication Number Publication Date
FR2433027A1 true FR2433027A1 (fr) 1980-03-07
FR2433027B1 FR2433027B1 (fr) 1980-12-12

Family

ID=9211680

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7823336A Granted FR2433027A1 (fr) 1978-08-08 1978-08-08 Nouveau procede de preparation de derives de la doxorubicine

Country Status (1)

Country Link
FR (1) FR2433027A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2585569A1 (fr) * 1985-08-02 1987-02-06 Erba Farmitalia Solutions injectables, pretes a l'emploi, contenant un agent antitumeur du type anthracycline-glucoside

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2585569A1 (fr) * 1985-08-02 1987-02-06 Erba Farmitalia Solutions injectables, pretes a l'emploi, contenant un agent antitumeur du type anthracycline-glucoside

Also Published As

Publication number Publication date
FR2433027B1 (fr) 1980-12-12

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Legal Events

Date Code Title Description
ST Notification of lapse