NL191507B - Afgedichte houder, bevattend een voor injectie gerede zure oplossing, die in hoofdzaak bestaat uit een fysiologisch aanvaardbaar zout van een antracyclineglycoside opgelost in een fysiologisch water bevattend oplosmiddel daarvoor. - Google Patents
Afgedichte houder, bevattend een voor injectie gerede zure oplossing, die in hoofdzaak bestaat uit een fysiologisch aanvaardbaar zout van een antracyclineglycoside opgelost in een fysiologisch water bevattend oplosmiddel daarvoor.Info
- Publication number
- NL191507B NL191507B NL8601698A NL8601698A NL191507B NL 191507 B NL191507 B NL 191507B NL 8601698 A NL8601698 A NL 8601698A NL 8601698 A NL8601698 A NL 8601698A NL 191507 B NL191507 B NL 191507B
- Authority
- NL
- Netherlands
- Prior art keywords
- injection
- acceptable salt
- acid solution
- consisting essentially
- physiologically acceptable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858519452A GB8519452D0 (en) | 1985-08-02 | 1985-08-02 | Injectable solutions |
GB8519452 | 1985-08-02 |
Publications (3)
Publication Number | Publication Date |
---|---|
NL8601698A NL8601698A (nl) | 1987-03-02 |
NL191507B true NL191507B (nl) | 1995-04-18 |
NL191507C NL191507C (nl) | 2000-02-16 |
Family
ID=10583216
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL8601698A NL191507C (nl) | 1985-08-02 | 1986-06-27 | Afgedichte houder, bevattend een voor injectie gerede zure oplossing, die in hoofdzaak bestaat uit een fysiologisch aanvaardbaar zout van een antracyclineglycoside opgelost in een fysiologisch water bevattend oplosmiddel daarvoor. |
NL300011C NL300011I1 (nl) | 1985-08-02 | 2000-07-18 | Afgedichte houder, bevattend een voor injectie ge rede zure oplossing, die in hoofdzaak bestaat uit een fysiologisch aanvaardbaar zout van een antracyclineglycoside opgelost in een fysiologisch water bevattend oplosmiddel daarvoor. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL300011C NL300011I1 (nl) | 1985-08-02 | 2000-07-18 | Afgedichte houder, bevattend een voor injectie ge rede zure oplossing, die in hoofdzaak bestaat uit een fysiologisch aanvaardbaar zout van een antracyclineglycoside opgelost in een fysiologisch water bevattend oplosmiddel daarvoor. |
Country Status (34)
Country | Link |
---|---|
US (1) | US4946831A (nl) |
JP (1) | JPH0655667B2 (nl) |
KR (1) | KR920001773B1 (nl) |
CN (1) | CN1064531C (nl) |
AT (1) | AT397463B (nl) |
BE (1) | BE905202A (nl) |
BG (1) | BG60425B2 (nl) |
CA (1) | CA1291037C (nl) |
CH (2) | CH690490C2 (nl) |
CS (1) | CS277561B6 (nl) |
CY (1) | CY1592A (nl) |
DE (1) | DE3621844C2 (nl) |
DK (1) | DK167557B1 (nl) |
ES (1) | ES8801580A1 (nl) |
FI (1) | FI86800C (nl) |
FR (1) | FR2585569B1 (nl) |
GB (2) | GB8519452D0 (nl) |
GR (1) | GR861556B (nl) |
HK (1) | HK93990A (nl) |
HU (1) | HU196123B (nl) |
IE (1) | IE59297B1 (nl) |
IL (1) | IL79129A (nl) |
IT (1) | IT1204906B (nl) |
NL (2) | NL191507C (nl) |
NO (1) | NO170913C (nl) |
NZ (1) | NZ216604A (nl) |
PH (1) | PH22332A (nl) |
PT (1) | PT82865B (nl) |
RU (2) | RU1837883C (nl) |
SE (1) | SE466383C (nl) |
SG (1) | SG80690G (nl) |
UA (1) | UA29383C2 (nl) |
YU (1) | YU44788B (nl) |
ZA (1) | ZA864792B (nl) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5977082A (en) | 1985-08-02 | 1999-11-02 | Pharmacia & Upjohn Company | Injectable ready-to-use solutions containing an antitumor anthracycline glycoside |
US5124318A (en) * | 1985-08-02 | 1992-06-23 | Farmitalia Carlo Erba S.R.L. | Injectable ready-to-use solutions containing an antitumor anthracycline glycoside |
US5124317A (en) | 1985-08-02 | 1992-06-23 | Farmitalia Carlo Erba S.P.A. | Injectable ready-to-use solutions containing an antitumor anthracycline glycoside |
EP1283044A3 (en) * | 1986-12-05 | 2003-05-14 | Pharmacia Italia S.p.A. | Injectable ready-to-use solutions containing an antitumor anthracycline glycoside |
FI883337A (fi) * | 1987-07-16 | 1989-01-17 | Bristol Myers Co | Icke-vattenloesningar av doxorubicinhydroklorin. |
FI883338A (fi) * | 1987-07-16 | 1989-01-17 | Bristol Myers Co | Vattenloesningar av doxorubicinhydroklorid. |
DE3801178A1 (de) * | 1988-01-18 | 1989-07-27 | Hoechst Ag | Stabilisierte trockenzubereitung zytostatisch wirksamer anthracyclin-antibiotika und verfahren zu ihrer herstellung |
DE68905577T2 (de) * | 1988-12-05 | 1993-07-01 | Bristol Myers Squibb Co | Doxorubicin-loesungen. |
FI895733A0 (fi) * | 1988-12-05 | 1989-11-30 | Bristol Myers Squibb Co | Vattenloesningar av doxorubicin. |
GB9200247D0 (en) * | 1992-01-07 | 1992-02-26 | Erba Carlo Spa | Pharmaceutical compositions containing polymer derivative-bound anthracycline glycosides and a method for their preparation |
DE19544532C2 (de) * | 1995-11-29 | 1997-12-11 | Pharma Dynamics Gmbh | Verfahren zum Herstellen eines Doxorubicin-Lyophilisats |
ATE195526T1 (de) * | 1996-12-16 | 2000-09-15 | Pharmachemie Bv | Verfahren zur herstellung von epirubicin oder zusatzsalzen davon, von daunorubicin |
BR9713661A (pt) | 1996-12-30 | 2000-10-24 | Battelle Memorial Institute | Formulação e método para o tratamento de neoplasmas por inalação |
US20090253220A1 (en) * | 2003-10-28 | 2009-10-08 | Sukanta Banerjee | Absorbing Biomolecules into Gel-Shell Beads |
CA2606390A1 (en) * | 2005-05-11 | 2006-11-16 | Sicor, Inc. | Stable lyophilized anthracycline glycosides |
US20140378404A1 (en) * | 2011-10-25 | 2014-12-25 | Nektar Therapeutics | Treatment of Patients Suffering from Cancer |
CN102614118B (zh) * | 2012-03-15 | 2014-04-30 | 北京协和药厂 | 注射用盐酸表柔比星制剂的制备方法及制剂 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
YU33730B (en) * | 1967-04-18 | 1978-02-28 | Farmaceutici Italia | Process for preparing a novel antibiotic substance and salts thereof |
GB1457632A (en) * | 1974-03-22 | 1976-12-08 | Farmaceutici Italia | Adriamycins |
GB1500421A (en) * | 1975-01-22 | 1978-02-08 | Farmaceutici Italia | Optically active anthracyclinones |
US4039663A (en) * | 1975-03-19 | 1977-08-02 | Societa' Farmaceutici Italia S.P.A. | Daunomycins, process for their uses and intermediates |
FR2314726A1 (fr) * | 1975-06-16 | 1977-01-14 | Rhone Poulenc Ind | Nouveaux derives du naphtagene, leur preparation et les compositions qui les contiennent |
GB1511559A (en) * | 1975-09-26 | 1978-05-24 | Farmaceutici Italia | Anthracycline glycosides |
FR2397425A1 (fr) * | 1977-07-11 | 1979-02-09 | Rhone Poulenc Ind | Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent |
DE2738656A1 (de) * | 1977-08-26 | 1979-03-08 | Microbial Chem Res Found | Anthracyclinglycoside, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
US4177264A (en) * | 1977-10-17 | 1979-12-04 | Sri International | N-benzyl anthracyclines |
GB2007645B (en) * | 1977-10-17 | 1982-05-12 | Stanford Res Inst Int | Benzyl anthracyclines and pharmaceutical compositions containing them |
FR2430425A1 (fr) * | 1978-07-07 | 1980-02-01 | Rhone Poulenc Ind | Nouveaux derives de la daunorubicine, leur preparation et les compositions pharmaceutiques qui les contiennent |
FR2433027A1 (fr) * | 1978-08-08 | 1980-03-07 | Rhone Poulenc Ind | Nouveau procede de preparation de derives de la doxorubicine |
US4325947A (en) * | 1981-05-12 | 1982-04-20 | Farmitalia Carlo Erba S.P.A. | 4-Demethoxy-4'-deoxydoxorubicin |
US4438105A (en) * | 1982-04-19 | 1984-03-20 | Farmaitalia Carlo Erba S.P.A | 4'-Iododerivatives of anthracycline glycosides |
US4464529A (en) * | 1982-07-20 | 1984-08-07 | Sri International | Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin |
JPS6092212A (ja) * | 1983-10-26 | 1985-05-23 | Kyowa Hakko Kogyo Co Ltd | ドキソルビシン塩の製剤 |
EP1283044A3 (en) * | 1986-12-05 | 2003-05-14 | Pharmacia Italia S.p.A. | Injectable ready-to-use solutions containing an antitumor anthracycline glycoside |
-
1985
- 1985-08-02 GB GB858519452A patent/GB8519452D0/en active Pending
-
1986
- 1986-06-16 YU YU1035/86A patent/YU44788B/xx unknown
- 1986-06-16 GR GR861556A patent/GR861556B/el unknown
- 1986-06-17 IE IE159886A patent/IE59297B1/en not_active IP Right Cessation
- 1986-06-17 IL IL79129A patent/IL79129A/xx not_active IP Right Cessation
- 1986-06-18 GB GB8614800A patent/GB2178311B/en not_active Expired
- 1986-06-19 SE SE8602743A patent/SE466383C/sv not_active IP Right Cessation
- 1986-06-19 FI FI862629A patent/FI86800C/fi not_active IP Right Cessation
- 1986-06-19 ES ES556291A patent/ES8801580A1/es not_active Expired
- 1986-06-20 HU HU862614A patent/HU196123B/hu unknown
- 1986-06-20 NZ NZ216604A patent/NZ216604A/xx unknown
- 1986-06-20 FR FR868608964A patent/FR2585569B1/fr not_active Expired - Lifetime
- 1986-06-24 CH CH02158/99A patent/CH690490C2/de not_active IP Right Cessation
- 1986-06-24 CH CH2534/86A patent/CH668911C1/de not_active IP Right Cessation
- 1986-06-25 CS CS864708A patent/CS277561B6/cs not_active IP Right Cessation
- 1986-06-26 IT IT20917/86A patent/IT1204906B/it active Protection Beyond IP Right Term
- 1986-06-26 NO NO19862587A patent/NO170913C/no not_active IP Right Cessation
- 1986-06-27 PT PT82865A patent/PT82865B/pt unknown
- 1986-06-27 NL NL8601698A patent/NL191507C/nl not_active IP Right Cessation
- 1986-06-27 UA UA5011936A patent/UA29383C2/uk unknown
- 1986-06-27 ZA ZA864792A patent/ZA864792B/xx unknown
- 1986-06-27 RU SU864027713A patent/RU1837883C/ru active
- 1986-06-27 CA CA000512613A patent/CA1291037C/en not_active Expired - Lifetime
- 1986-06-27 JP JP61149878A patent/JPH0655667B2/ja not_active Expired - Lifetime
- 1986-06-27 DK DK306286A patent/DK167557B1/da not_active IP Right Cessation
- 1986-06-28 CN CN86104283A patent/CN1064531C/zh not_active Expired - Lifetime
- 1986-06-28 KR KR1019860005231A patent/KR920001773B1/ko not_active IP Right Cessation
- 1986-06-30 AT AT0176886A patent/AT397463B/de active Protection Beyond IP Right Term
- 1986-06-30 PH PH33966A patent/PH22332A/en unknown
- 1986-06-30 DE DE3621844A patent/DE3621844C2/de not_active Revoked
- 1986-07-31 BE BE0/216997A patent/BE905202A/fr not_active IP Right Cessation
-
1989
- 1989-07-27 US US07/385,999 patent/US4946831A/en not_active Expired - Lifetime
-
1990
- 1990-10-04 SG SG806/90A patent/SG80690G/en unknown
- 1990-11-15 HK HK939/90A patent/HK93990A/xx not_active IP Right Cessation
-
1992
- 1992-04-03 CY CY1592A patent/CY1592A/xx unknown
- 1992-06-24 RU SU5011936A patent/RU2110263C1/ru active
-
1993
- 1993-12-21 BG BG98321A patent/BG60425B2/bg unknown
-
2000
- 2000-07-18 NL NL300011C patent/NL300011I1/nl unknown
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BA | A request for search or an international-type search has been filed | ||
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CNR | Transfer of rights (patent application after its laying open for public inspection) |
Free format text: ERBAMONT INDUSTRIALE S.R.L. |
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DNT | Communications of changes of names of applicants whose applications have been laid open to public inspection |
Free format text: ERBA S.R.L. FARMITALIA CARLO - |
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CNR | Transfer of rights (patent application after its laying open for public inspection) |
Free format text: PHARMACIA S.P.A. |
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R1B | Notice of opposition during period of laying open |
Free format text: PHARMACHEMIE B.V. TE 2031 BP HAARLEM. |
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DNT | Communications of changes of names of applicants whose applications have been laid open to public inspection |
Free format text: PHARMACIA & UPJOHN S.P.A. |
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NP1G | Patent granted (not automatically) [patent specification modified] | ||
AC1 | Application for a supplementary protection certificate |
Free format text: 300011, 20000718 |
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BC1 | Further communications concerning applications for a supplementary protection certificate |
Free format text: 300011 |
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TNT | Modifications of names of proprietors of patents or applicants of examined patent applications |
Owner name: PHARMACIA ITALIA S.P.A. |
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V4 | Discontinued because of reaching the maximum lifetime of a patent |
Effective date: 20060627 |