DK306286D0 - Injicerbar faerdig oploesning indeholdende et anthracyclinglycosid medantitumor-aktivitet - Google Patents

Injicerbar faerdig oploesning indeholdende et anthracyclinglycosid medantitumor-aktivitet

Info

Publication number
DK306286D0
DK306286D0 DK306286A DK306286A DK306286D0 DK 306286 D0 DK306286 D0 DK 306286D0 DK 306286 A DK306286 A DK 306286A DK 306286 A DK306286 A DK 306286A DK 306286 D0 DK306286 D0 DK 306286D0
Authority
DK
Denmark
Prior art keywords
medantitumor
anthracycling
lycoside
injectable
activity
Prior art date
Application number
DK306286A
Other languages
English (en)
Other versions
DK167557B1 (da
DK306286A (da
Inventor
Gaetano Gatti
Diego Oldani
Giuseppe Bottoni
Carlo Confalonieri
Luciano Gambini
Ponti Roberto De
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10583216&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK306286(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of DK306286D0 publication Critical patent/DK306286D0/da
Publication of DK306286A publication Critical patent/DK306286A/da
Application granted granted Critical
Publication of DK167557B1 publication Critical patent/DK167557B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
DK306286A 1985-08-02 1986-06-27 Injicerbar, brugsklar, steril pyrogenfri anthracyclinglycosidoploesning og fremgangsmaade til dens fremstilling DK167557B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858519452A GB8519452D0 (en) 1985-08-02 1985-08-02 Injectable solutions
GB8519452 1985-08-02

Publications (3)

Publication Number Publication Date
DK306286D0 true DK306286D0 (da) 1986-06-27
DK306286A DK306286A (da) 1987-02-03
DK167557B1 DK167557B1 (da) 1993-11-22

Family

ID=10583216

Family Applications (1)

Application Number Title Priority Date Filing Date
DK306286A DK167557B1 (da) 1985-08-02 1986-06-27 Injicerbar, brugsklar, steril pyrogenfri anthracyclinglycosidoploesning og fremgangsmaade til dens fremstilling

Country Status (34)

Country Link
US (1) US4946831A (da)
JP (1) JPH0655667B2 (da)
KR (1) KR920001773B1 (da)
CN (1) CN1064531C (da)
AT (1) AT397463B (da)
BE (1) BE905202A (da)
BG (1) BG60425B2 (da)
CA (1) CA1291037C (da)
CH (2) CH690490C2 (da)
CS (1) CS277561B6 (da)
CY (1) CY1592A (da)
DE (1) DE3621844C2 (da)
DK (1) DK167557B1 (da)
ES (1) ES8801580A1 (da)
FI (1) FI86800C (da)
FR (1) FR2585569B1 (da)
GB (2) GB8519452D0 (da)
GR (1) GR861556B (da)
HK (1) HK93990A (da)
HU (1) HU196123B (da)
IE (1) IE59297B1 (da)
IL (1) IL79129A (da)
IT (1) IT1204906B (da)
NL (2) NL191507C (da)
NO (1) NO170913C (da)
NZ (1) NZ216604A (da)
PH (1) PH22332A (da)
PT (1) PT82865B (da)
RU (2) RU1837883C (da)
SE (1) SE466383C (da)
SG (1) SG80690G (da)
UA (1) UA29383C2 (da)
YU (1) YU44788B (da)
ZA (1) ZA864792B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977082A (en) 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124318A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.R.L. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124317A (en) 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
EP1283044A3 (en) * 1986-12-05 2003-05-14 Pharmacia Italia S.p.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
FI883337A (fi) * 1987-07-16 1989-01-17 Bristol Myers Co Icke-vattenloesningar av doxorubicinhydroklorin.
FI883338A (fi) * 1987-07-16 1989-01-17 Bristol Myers Co Vattenloesningar av doxorubicinhydroklorid.
DE3801178A1 (de) * 1988-01-18 1989-07-27 Hoechst Ag Stabilisierte trockenzubereitung zytostatisch wirksamer anthracyclin-antibiotika und verfahren zu ihrer herstellung
DE68905577T2 (de) * 1988-12-05 1993-07-01 Bristol Myers Squibb Co Doxorubicin-loesungen.
FI895733A0 (fi) * 1988-12-05 1989-11-30 Bristol Myers Squibb Co Vattenloesningar av doxorubicin.
GB9200247D0 (en) * 1992-01-07 1992-02-26 Erba Carlo Spa Pharmaceutical compositions containing polymer derivative-bound anthracycline glycosides and a method for their preparation
DE19544532C2 (de) * 1995-11-29 1997-12-11 Pharma Dynamics Gmbh Verfahren zum Herstellen eines Doxorubicin-Lyophilisats
ATE195526T1 (de) * 1996-12-16 2000-09-15 Pharmachemie Bv Verfahren zur herstellung von epirubicin oder zusatzsalzen davon, von daunorubicin
BR9713661A (pt) 1996-12-30 2000-10-24 Battelle Memorial Institute Formulação e método para o tratamento de neoplasmas por inalação
US20090253220A1 (en) * 2003-10-28 2009-10-08 Sukanta Banerjee Absorbing Biomolecules into Gel-Shell Beads
CA2606390A1 (en) * 2005-05-11 2006-11-16 Sicor, Inc. Stable lyophilized anthracycline glycosides
US20140378404A1 (en) * 2011-10-25 2014-12-25 Nektar Therapeutics Treatment of Patients Suffering from Cancer
CN102614118B (zh) * 2012-03-15 2014-04-30 北京协和药厂 注射用盐酸表柔比星制剂的制备方法及制剂

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
GB1457632A (en) * 1974-03-22 1976-12-08 Farmaceutici Italia Adriamycins
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates
FR2314726A1 (fr) * 1975-06-16 1977-01-14 Rhone Poulenc Ind Nouveaux derives du naphtagene, leur preparation et les compositions qui les contiennent
GB1511559A (en) * 1975-09-26 1978-05-24 Farmaceutici Italia Anthracycline glycosides
FR2397425A1 (fr) * 1977-07-11 1979-02-09 Rhone Poulenc Ind Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent
DE2738656A1 (de) * 1977-08-26 1979-03-08 Microbial Chem Res Found Anthracyclinglycoside, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4177264A (en) * 1977-10-17 1979-12-04 Sri International N-benzyl anthracyclines
GB2007645B (en) * 1977-10-17 1982-05-12 Stanford Res Inst Int Benzyl anthracyclines and pharmaceutical compositions containing them
FR2430425A1 (fr) * 1978-07-07 1980-02-01 Rhone Poulenc Ind Nouveaux derives de la daunorubicine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2433027A1 (fr) * 1978-08-08 1980-03-07 Rhone Poulenc Ind Nouveau procede de preparation de derives de la doxorubicine
US4325947A (en) * 1981-05-12 1982-04-20 Farmitalia Carlo Erba S.P.A. 4-Demethoxy-4'-deoxydoxorubicin
US4438105A (en) * 1982-04-19 1984-03-20 Farmaitalia Carlo Erba S.P.A 4'-Iododerivatives of anthracycline glycosides
US4464529A (en) * 1982-07-20 1984-08-07 Sri International Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin
JPS6092212A (ja) * 1983-10-26 1985-05-23 Kyowa Hakko Kogyo Co Ltd ドキソルビシン塩の製剤
EP1283044A3 (en) * 1986-12-05 2003-05-14 Pharmacia Italia S.p.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside

Also Published As

Publication number Publication date
US4946831A (en) 1990-08-07
CS277561B6 (en) 1993-03-17
JPH0655667B2 (ja) 1994-07-27
IT8620917A0 (it) 1986-06-26
CH690490C2 (de) 2000-09-29
FR2585569A1 (fr) 1987-02-06
AT397463B (de) 1994-04-25
CY1592A (en) 1992-04-03
NO170913C (no) 2003-10-10
DE3621844A1 (de) 1987-03-05
RU2110263C1 (ru) 1998-05-10
SE466383B (sv) 1992-02-10
FI862629A0 (fi) 1986-06-19
SE466383C (sv) 1995-10-19
KR870001828A (ko) 1987-03-28
NO862587L (no) 1987-02-03
BE905202A (fr) 1987-02-02
ATA176886A (de) 1993-09-15
CA1291037C (en) 1991-10-22
YU44788B (en) 1991-02-28
CS470886A3 (en) 1992-11-18
BG60425B2 (bg) 1995-03-31
CH668911C1 (de) 2000-05-31
GB8519452D0 (en) 1985-09-11
PT82865B (pt) 1989-01-17
GB2178311A (en) 1987-02-11
NL300011I1 (nl) 2000-10-02
SG80690G (en) 1990-11-23
HU196123B (en) 1988-10-28
IL79129A0 (en) 1986-09-30
NO862587D0 (no) 1986-06-26
RU1837883C (ru) 1993-08-30
NL191507B (nl) 1995-04-18
IE861598L (en) 1987-02-02
SE8602743D0 (sv) 1986-06-19
NZ216604A (en) 1989-10-27
IL79129A (en) 1992-03-29
IT1204906B (it) 1989-03-10
FI862629A (fi) 1987-02-03
HK93990A (en) 1990-11-23
NL191507C (nl) 2000-02-16
FR2585569B1 (fr) 1990-01-19
DK167557B1 (da) 1993-11-22
AU5885886A (en) 1987-02-12
GB8614800D0 (en) 1986-07-23
ES556291A0 (es) 1988-02-16
ZA864792B (en) 1988-02-24
ES8801580A1 (es) 1988-02-16
AU598197B2 (en) 1990-06-21
CH668911A5 (de) 1989-02-15
DE3621844C2 (de) 1994-02-17
HUT42326A (en) 1987-07-28
NL8601698A (nl) 1987-03-02
PT82865A (en) 1986-07-01
KR920001773B1 (ko) 1992-03-02
UA29383C2 (uk) 2000-11-15
GB2178311B (en) 1989-10-11
CN1064531C (zh) 2001-04-18
DK306286A (da) 1987-02-03
YU103586A (en) 1988-04-30
FI86800C (fi) 1999-10-28
SE8602743L (sv) 1987-02-03
GR861556B (en) 1986-10-17
PH22332A (en) 1988-07-29
IE59297B1 (en) 1994-02-09
NO170913B (no) 1992-09-21
CN86104283A (zh) 1987-01-28
JPS6248629A (ja) 1987-03-03
FI86800B (fi) 1992-07-15

Similar Documents

Publication Publication Date Title
FR2581863B1 (fr) Incubateur
DK470787D0 (da) Enzymer med aendret aktivitet
DK268786D0 (da) Aktive forbindelser
BR8606543A (pt) Construcao extensivel
FR2590799B1 (fr) Seringue
DK500086A (da) Substituerede benzamider
DK306286A (da) Injicerbar faerdig oploesning indeholdende et anthracyclinglycosid medantitumor-aktivitet
DK495586A (da) Piperazinoisothiazoloner med psykotrop aktivitet
IT1188423B (it) Filatoio
IT1191712B (it) Lavastoviglie per impiego
DK139486A (da) Katalysatorer
DK303886D0 (da) Aktive forbindelser
DK492386D0 (da) Bicycliske imider med psykotrop aktivitet
IT1196976B (it) Filatoio
KR870001673U (ko) 채반
ES288629Y (es) Jeringa
DK138585D0 (da) Vaskemiddel
KR860009463U (ko) 세척기
KR860013013U (ko) 주사기
KR890012708U (ko) 활동완구
RO93177A2 (ro) Solutie cicatrizanta
KR870013192U (ko) 활동완구
ES276839Y (es) Jeringuilla
BR8406387A (pt) Seringa
SE8500829D0 (sv) Virknal

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PPF Opposition filed
PUP Patent expired