WO2009072548A1 - 血液処理用多孔質中空糸膜 - Google Patents

血液処理用多孔質中空糸膜 Download PDF

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Publication number
WO2009072548A1
WO2009072548A1 PCT/JP2008/072027 JP2008072027W WO2009072548A1 WO 2009072548 A1 WO2009072548 A1 WO 2009072548A1 JP 2008072027 W JP2008072027 W JP 2008072027W WO 2009072548 A1 WO2009072548 A1 WO 2009072548A1
Authority
WO
WIPO (PCT)
Prior art keywords
hollow fiber
fiber membrane
treating blood
porous hollow
average
Prior art date
Application number
PCT/JP2008/072027
Other languages
English (en)
French (fr)
Inventor
Hidetoshi Hidaka
Takahiro Ichi
Original Assignee
Asahi Kasei Kuraray Medical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40717725&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2009072548(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Asahi Kasei Kuraray Medical Co., Ltd. filed Critical Asahi Kasei Kuraray Medical Co., Ltd.
Priority to CN2008801192800A priority Critical patent/CN101888863B/zh
Priority to ES08858348T priority patent/ES2394841T5/es
Priority to JP2009544703A priority patent/JP5211071B2/ja
Priority to US12/746,075 priority patent/US9616393B2/en
Priority to KR1020107010878A priority patent/KR101177199B1/ko
Priority to EP08858348.9A priority patent/EP2216060B2/en
Priority to CA2707685A priority patent/CA2707685C/en
Publication of WO2009072548A1 publication Critical patent/WO2009072548A1/ja

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/08—Hollow fibre membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/08—Hollow fibre membranes
    • B01D69/087—Details relating to the spinning process
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/44—Polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds, not provided for in a single one of groups B01D71/26-B01D71/42
    • B01D71/441—Polyvinylpyrrolidone
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/66—Polymers having sulfur in the main chain, with or without nitrogen, oxygen or carbon only
    • B01D71/68—Polysulfones; Polyethersulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/02—Details relating to pores or porosity of the membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/02—Details relating to pores or porosity of the membranes
    • B01D2325/0281—Fibril, or microfibril structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/04—Characteristic thickness
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/20—Specific permeability or cut-off range

Landscapes

  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)
  • Artificial Filaments (AREA)

Abstract

　薄膜化されたポリスルホン系中空糸膜であっても、生産工程や移送中あるいは取扱い時に機械的損傷を生じ難く、しかも分画性に優れる血液処理用の多孔質中空糸膜を提供する。 　ポリスルホン系ポリマーとポリビニルピロリドンとを含み、膜厚方向の内側から外側に向けて孔径が拡大するグラジェント多孔質構造を成す血液処理用多孔質中空糸膜において、該多孔質構造は膜厚が２５μｍ以上４０μｍ未満であり、かつ、全平均太さが１００～２００μｍのフィブリルが、膜厚方向の外側平均太さ（Ｔｏ）と内側平均太さ（Ｔｉ）の比（Ｔｏ／Ｔｉ）が２以下となるように配置されてなることを特徴とする血液処理用多孔質中空糸膜。
PCT/JP2008/072027 2007-12-06 2008-12-04 血液処理用多孔質中空糸膜 WO2009072548A1 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CN2008801192800A CN101888863B (zh) 2007-12-06 2008-12-04 血液处理用多孔中空纤维膜
ES08858348T ES2394841T5 (es) 2007-12-06 2008-12-04 Membrana de fibras huecas porosa para el tratamiento de la sangre
JP2009544703A JP5211071B2 (ja) 2007-12-06 2008-12-04 血液処理用多孔質中空糸膜
US12/746,075 US9616393B2 (en) 2007-12-06 2008-12-04 Porous hollow fiber membrane for treating blood
KR1020107010878A KR101177199B1 (ko) 2007-12-06 2008-12-04 혈액 처리용 다공질 중공사막
EP08858348.9A EP2216060B2 (en) 2007-12-06 2008-12-04 Porous hollow fiber membrane for blood treatment
CA2707685A CA2707685C (en) 2007-12-06 2008-12-04 Porous hollow fiber membrane for treating blood

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-316214 2007-12-06
JP2007316214 2007-12-06

Publications (1)

Publication Number Publication Date
WO2009072548A1 true WO2009072548A1 (ja) 2009-06-11

Family

ID=40717725

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/072027 WO2009072548A1 (ja) 2007-12-06 2008-12-04 血液処理用多孔質中空糸膜

Country Status (9)

Country Link
US (1) US9616393B2 (ja)
EP (1) EP2216060B2 (ja)
JP (1) JP5211071B2 (ja)
KR (1) KR101177199B1 (ja)
CN (1) CN101888863B (ja)
CA (1) CA2707685C (ja)
ES (1) ES2394841T5 (ja)
TW (1) TWI396565B (ja)
WO (1) WO2009072548A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013085826A (ja) * 2011-10-20 2013-05-13 Asahi Kasei Medical Co Ltd 血液浄化器
JP2016077604A (ja) * 2014-10-17 2016-05-16 旭化成メディカル株式会社 中空糸膜型血液浄化器
JP2017035644A (ja) * 2015-08-06 2017-02-16 旭化成メディカル株式会社 中空糸膜モジュール及びその製造方法
WO2023080238A1 (ja) * 2021-11-08 2023-05-11 旭化成メディカル株式会社 中空糸膜型血液浄化器

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US10626399B2 (en) 2010-01-28 2020-04-21 The Board Of Trustees Of The Leland Stanford Junior University Methods of treating cognitive symptoms of an aging-associated impairment by modulating C-C chemokine receptor type 3 (CCR3)
US20160208011A1 (en) 2010-01-28 2016-07-21 The Board Of Trustees Of The Leland Stanford Junior University Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same
US9161968B2 (en) 2011-04-08 2015-10-20 The Board Of Trustees Of The Leland Stanford Junior University Methods of neuroprotection involving macrophage colony stimulating factor receptor agonists
EP2845641B1 (en) 2013-09-05 2018-05-09 Gambro Lundia AB Permselective asymmetric membranes with high molecular weight polyvinylpyrrolidone, the preparation and use thereof
EA035336B1 (ru) 2013-12-09 2020-05-29 Зе Боард Оф Трастиз Оф Зе Леланд Стэнфорд Джуниор Юниверсити Способ лечения связанного со старением когнитивного расстройства или заболевания
US10905779B2 (en) 2013-12-09 2021-02-02 The Board Of Trustees Of The Leland Stanford Junior University Methods for screening human blood products comprising plasma using immunocompromised rodent models
ES2927071T3 (es) 2014-02-06 2022-11-02 Gambro Lundia Ab Hemodializador para purificar la sangre
KR102346383B1 (ko) 2014-02-06 2022-01-04 감브로 룬디아 아베 혈액 정화를 위한 멤브레인
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KR20210041137A (ko) 2015-06-15 2021-04-14 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 노화와 연관된 질환을 치료하기 위한 방법 및 조성물
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EP3508233B1 (en) * 2016-08-31 2023-03-01 Terumo Kabushiki Kaisha Heat exchanger, artificial lung, and method of manufacturing heat exchanger
US11040068B2 (en) 2017-04-26 2021-06-22 Alkahest, Inc. Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
CN110709098B (zh) 2017-04-26 2024-01-30 万能溶剂有限公司 用血浆和血浆制品治疗认知障碍和运动障碍的给药方案
WO2020086469A1 (en) 2018-10-26 2020-04-30 Alkahest, Inc. Use of plasma and plasma fractions for improvement of pain, wound healing, and postoperative recovery
CN113926316B (zh) * 2021-11-23 2024-01-26 江苏巨澜纳米科技有限公司 一种防漏增湿复合中空纤维膜、制备方法及其应用

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013085826A (ja) * 2011-10-20 2013-05-13 Asahi Kasei Medical Co Ltd 血液浄化器
JP2016077604A (ja) * 2014-10-17 2016-05-16 旭化成メディカル株式会社 中空糸膜型血液浄化器
JP2017035644A (ja) * 2015-08-06 2017-02-16 旭化成メディカル株式会社 中空糸膜モジュール及びその製造方法
WO2023080238A1 (ja) * 2021-11-08 2023-05-11 旭化成メディカル株式会社 中空糸膜型血液浄化器

Also Published As

Publication number Publication date
ES2394841T3 (es) 2013-02-06
JP5211071B2 (ja) 2013-06-12
EP2216060B1 (en) 2012-10-03
JPWO2009072548A1 (ja) 2011-04-28
CN101888863A (zh) 2010-11-17
EP2216060A1 (en) 2010-08-11
ES2394841T5 (es) 2021-10-29
US9616393B2 (en) 2017-04-11
EP2216060B2 (en) 2021-03-17
KR101177199B1 (ko) 2012-08-24
CA2707685A1 (en) 2009-06-11
TW200938239A (en) 2009-09-16
US20100258496A1 (en) 2010-10-14
KR20100080842A (ko) 2010-07-12
TWI396565B (zh) 2013-05-21
EP2216060A4 (en) 2011-05-25
CN101888863B (zh) 2012-11-28
CA2707685C (en) 2014-05-27

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