WO2008093670A1 - ブドウ果皮・種子乳酸菌発酵物、並びにそれを利用した医薬及び食品 - Google Patents

ブドウ果皮・種子乳酸菌発酵物、並びにそれを利用した医薬及び食品 Download PDF

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Publication number
WO2008093670A1
WO2008093670A1 PCT/JP2008/051293 JP2008051293W WO2008093670A1 WO 2008093670 A1 WO2008093670 A1 WO 2008093670A1 JP 2008051293 W JP2008051293 W JP 2008051293W WO 2008093670 A1 WO2008093670 A1 WO 2008093670A1
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WIPO (PCT)
Prior art keywords
seed
fermentation product
lactic acid
pharmaceutical agent
grape skin
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PCT/JP2008/051293
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English (en)
French (fr)
Inventor
Takanari Tominaga
Yoshio Kumazawa
Kiichiro Kawaguchi
Takao Mukai
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Tk Bio-Research Laboratory Co., Ltd.
Kitasato University Graduate School Of Science
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Application filed by Tk Bio-Research Laboratory Co., Ltd., Kitasato University Graduate School Of Science filed Critical Tk Bio-Research Laboratory Co., Ltd.
Priority to JP2008556104A priority Critical patent/JP4990297B2/ja
Publication of WO2008093670A1 publication Critical patent/WO2008093670A1/ja

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/03—Products from fruits or vegetables; Preparation or treatment thereof consisting of whole pieces or fragments without mashing the original pieces
    • A23L19/07—Fruit waste products, e.g. from citrus peel or seeds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Food Science & Technology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Toxicology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

　本発明は、ブドウの果皮及び種子の少なくともいずれかを利用し、有用なブドウ果皮・種子乳酸菌発酵物を提供すること、また、前記ブドウ果皮・種子乳酸菌発酵物を利用し、II型糖尿病、高脂血症、肥満等のメタボリックシンドローム関連症状を効果的、かつ安全に治療、改善、又は予防することが可能な医薬及び食品、並びに、皮膚の美白・老化防止に効果的、かつ安全な医薬及び食品を提供することを目的とする。即ち、本発明は、ブドウの果皮及び種子の少なくともいずれかを乳酸菌で発酵させて得られることを特徴とするブドウ果皮・種子乳酸菌発酵物、並びに、前記ブドウ果皮・種子乳酸菌発酵物を含む医薬及び食品に関する。
PCT/JP2008/051293 2007-02-01 2008-01-29 ブドウ果皮・種子乳酸菌発酵物、並びにそれを利用した医薬及び食品 WO2008093670A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008556104A JP4990297B2 (ja) 2007-02-01 2008-01-29 ブドウ果皮・種子乳酸菌発酵物及びそれを利用した医薬

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007022922 2007-02-01
JP2007-022922 2007-02-01

Publications (1)

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WO2008093670A1 true WO2008093670A1 (ja) 2008-08-07

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JP (1) JP4990297B2 (ja)
WO (1) WO2008093670A1 (ja)

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JP2010279286A (ja) * 2009-06-04 2010-12-16 Nippon Bio Co Ltd ブドウ発酵物及びその製造方法
JP2011010648A (ja) * 2009-06-04 2011-01-20 Nippon Bio Co Ltd メタボリックシンドローム改善組成物
JP4795475B1 (ja) * 2010-04-15 2011-10-19 ワミレスコスメティックス株式会社 ウメ抽出物を含む剤
JP2012515541A (ja) * 2009-01-27 2012-07-12 ネステク ソシエテ アノニム チコリ酸及び／又はその誘導体を含む組成物
JP2012515542A (ja) * 2009-01-27 2012-07-12 ネステク ソシエテ アノニム カフタル酸及び／又はその誘導体を含む組成物
JP2014504155A (ja) * 2010-11-30 2014-02-20 株式會社アモーレパシフィック 皮膚老化と関連した遺伝子及び皮膚老化を防止する物質をスクリーニングする方法
WO2015002043A1 (ja) * 2013-07-05 2015-01-08 株式会社ヤクルト本社 ペントシジン生成阻害剤
JP2015180221A (ja) * 2008-12-18 2015-10-15 メルシャン株式会社 清涼飲料、ぶどう果皮抽出液及びそれらの製造方法
KR20150135649A (ko) * 2014-05-23 2015-12-03 재단법인 전주농생명소재연구원 항당뇨 및 항고지혈증 활성을 갖는 락토바실러스 브레비스 jb pml-131 균주 및 이의 용도
KR101591978B1 (ko) 2014-05-23 2016-02-05 재단법인 전주농생명소재연구원 항당뇨 및 항고지혈증 활성을 갖는 락토바실러스 브레비스 jb pml-127 균주 및 이의 용도
JP2016113386A (ja) * 2014-12-12 2016-06-23 日本・バイオ株式会社 美白剤及び美白用化粧料
KR20160131019A (ko) * 2014-03-13 2016-11-15 액세스 비지니스 그룹 인터내셔날 엘엘씨 식물 제형의 상승작용적 조합을 통한 트리글리세리드 합성의 억제를 위한 조성물 및 방법
WO2017061353A1 (ja) * 2015-10-08 2017-04-13 株式会社ゲノム創薬研究所 スクロース摂取による血糖値上昇を抑制する物質の評価方法、スクリーニング方法及び製造方法
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KR101841021B1 (ko) 2017-04-06 2018-03-22 한국식품연구원 최종당화산물 저감 활성을 갖는 신규한 락토코쿠스 락티스 균주 및 이의 용도
KR101869740B1 (ko) 2017-06-23 2018-06-21 한국식품연구원 최종당화산물 저감 활성을 갖는 신규한 락토바실러스 파라카제이 균주 및 이의 용도
KR101869739B1 (ko) 2017-06-23 2018-06-21 한국식품연구원 최종당화산물 저감 활성을 갖는 신규한 락토바실러스 펜토서스 균주 및 이의 용도
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JP6087044B2 (ja) * 2008-12-18 2017-03-01 メルシャン株式会社 清涼飲料、ぶどう果皮抽出液及びそれらの製造方法
JP2015180221A (ja) * 2008-12-18 2015-10-15 メルシャン株式会社 清涼飲料、ぶどう果皮抽出液及びそれらの製造方法
JP2012515541A (ja) * 2009-01-27 2012-07-12 ネステク ソシエテ アノニム チコリ酸及び／又はその誘導体を含む組成物
JP2012515542A (ja) * 2009-01-27 2012-07-12 ネステク ソシエテ アノニム カフタル酸及び／又はその誘導体を含む組成物
WO2010110374A1 (ja) * 2009-03-26 2010-09-30 ビオフェルミン製薬株式会社 血糖降下作用増強剤
JP2010248185A (ja) * 2009-03-26 2010-11-04 Biofuerumin Seiyaku Kk 血糖降下作用増強剤
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JP2010279286A (ja) * 2009-06-04 2010-12-16 Nippon Bio Co Ltd ブドウ発酵物及びその製造方法
JP2011010648A (ja) * 2009-06-04 2011-01-20 Nippon Bio Co Ltd メタボリックシンドローム改善組成物
JP4795475B1 (ja) * 2010-04-15 2011-10-19 ワミレスコスメティックス株式会社 ウメ抽出物を含む剤
JP2013163643A (ja) * 2010-04-15 2013-08-22 Wamiles Cosmetics Kk ウメ抽出物を含む剤
JP2014504155A (ja) * 2010-11-30 2014-02-20 株式會社アモーレパシフィック 皮膚老化と関連した遺伝子及び皮膚老化を防止する物質をスクリーニングする方法
WO2015002043A1 (ja) * 2013-07-05 2015-01-08 株式会社ヤクルト本社 ペントシジン生成阻害剤
CN105358165A (zh) * 2013-07-05 2016-02-24 株式会社益力多本社 戊糖素生成抑制剂
JPWO2015002043A1 (ja) * 2013-07-05 2017-02-23 株式会社ヤクルト本社 ペントシジン生成阻害剤
US10426804B2 (en) 2013-07-05 2019-10-01 Kabushiki Kaisha Yakult Honsha Pentosidine production inhibitor
KR20160131019A (ko) * 2014-03-13 2016-11-15 액세스 비지니스 그룹 인터내셔날 엘엘씨 식물 제형의 상승작용적 조합을 통한 트리글리세리드 합성의 억제를 위한 조성물 및 방법
KR102263330B1 (ko) * 2014-03-13 2021-06-14 액세스 비지니스 그룹 인터내셔날 엘엘씨 식물 제형의 상승작용적 조합을 통한 트리글리세리드 합성의 억제를 위한 조성물 및 방법
KR101581826B1 (ko) 2014-05-23 2016-01-21 재단법인 전주농생명소재연구원 항당뇨 및 항고지혈증 활성을 갖는 락토바실러스 브레비스 jb pml-131 균주 및 이의 용도
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JPWO2017061353A1 (ja) * 2015-10-08 2018-08-30 株式会社ゲノム創薬研究所 スクロース摂取による血糖値上昇を抑制する物質の評価方法、スクリーニング方法及び製造方法
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KR101841021B1 (ko) 2017-04-06 2018-03-22 한국식품연구원 최종당화산물 저감 활성을 갖는 신규한 락토코쿠스 락티스 균주 및 이의 용도
KR101869740B1 (ko) 2017-06-23 2018-06-21 한국식품연구원 최종당화산물 저감 활성을 갖는 신규한 락토바실러스 파라카제이 균주 및 이의 용도
KR101869739B1 (ko) 2017-06-23 2018-06-21 한국식품연구원 최종당화산물 저감 활성을 갖는 신규한 락토바실러스 펜토서스 균주 및 이의 용도
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EP4134440A4 (en) * 2020-04-09 2024-04-24 Kabushiki Kaisha Yakult Honsha MALVA SYLVESTRIS FERMENTATION PRODUCT AND ITS USE
KR102414305B1 (ko) 2021-10-22 2022-06-30 주식회사 디캔트 과일 발효산물과 이를 이용한 향장용 조성물
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