WO2002008387A1 - Feuille cellulaire du type muscle cardiaque, construction tridimensionnelle, tissu du type muscle cardiaque et procede de production associe - Google Patents

Feuille cellulaire du type muscle cardiaque, construction tridimensionnelle, tissu du type muscle cardiaque et procede de production associe Download PDF

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Publication number
WO2002008387A1
WO2002008387A1 PCT/JP2001/005722 JP0105722W WO0208387A1 WO 2002008387 A1 WO2002008387 A1 WO 2002008387A1 JP 0105722 W JP0105722 W JP 0105722W WO 0208387 A1 WO0208387 A1 WO 0208387A1
Authority
WO
WIPO (PCT)
Prior art keywords
heart muscle
temperature
cell sheet
tissue
producing
Prior art date
Application number
PCT/JP2001/005722
Other languages
English (en)
French (fr)
Inventor
Teruo Okano
Tatsuya Shimizu
Masayuki Yamato
Akihiko Kikuchi
Original Assignee
Cellseed Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellseed Inc. filed Critical Cellseed Inc.
Priority to JP2002513872A priority Critical patent/JP4679795B2/ja
Priority to EP01945762A priority patent/EP1302535B1/en
Priority to DE60143892T priority patent/DE60143892D1/de
Priority to AT01945762T priority patent/ATE495766T1/de
Priority to US10/333,473 priority patent/US20040009566A1/en
Publication of WO2002008387A1 publication Critical patent/WO2002008387A1/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/383—Nerve cells, e.g. dendritic cells, Schwann cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3826—Muscle cells, e.g. smooth muscle cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2539/00—Supports and/or coatings for cell culture characterised by properties
    • C12N2539/10—Coating allowing for selective detachment of cells, e.g. thermoreactive coating
PCT/JP2001/005722 2000-07-21 2001-07-02 Feuille cellulaire du type muscle cardiaque, construction tridimensionnelle, tissu du type muscle cardiaque et procede de production associe WO2002008387A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2002513872A JP4679795B2 (ja) 2000-07-21 2001-07-02 心筋様細胞シート、３次元構造体、心筋様組織及びそれらの製造法
EP01945762A EP1302535B1 (en) 2000-07-21 2001-07-02 Heart muscle-like cell sheet, three-dimensional construct, heart muscle-like tissue and process for producing the same
DE60143892T DE60143892D1 (de) 2000-07-21 2001-07-02 Herzmuskel-ähnliche zellschicht, dreidimensionales konstrukt, herzmuskel-ähnliches gewebe und verfahren zur herstellung
AT01945762T ATE495766T1 (de) 2000-07-21 2001-07-02 Herzmuskel-ähnliche zellschicht, dreidimensionales konstrukt, herzmuskel-ähnliches gewebe und verfahren zur herstellung
US10/333,473 US20040009566A1 (en) 2000-07-21 2001-07-02 Heart muscle-like cell sheet, three-dimensional construct, heart muscle-like tissue and process for producing the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000-221385 2000-07-21
JP2000221385 2000-07-21

Publications (1)

Publication Number Publication Date
WO2002008387A1 true WO2002008387A1 (fr) 2002-01-31

Family

ID=18715796

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2001/005722 WO2002008387A1 (fr) 2000-07-21 2001-07-02 Feuille cellulaire du type muscle cardiaque, construction tridimensionnelle, tissu du type muscle cardiaque et procede de production associe

Country Status (7)

Country Link
US (1) US20040009566A1 (ja)
EP (2) EP2275532B1 (ja)
JP (2) JP4679795B2 (ja)
AT (1) ATE495766T1 (ja)
DE (1) DE60143892D1 (ja)
ES (2) ES2357764T3 (ja)
WO (1) WO2002008387A1 (ja)

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JP2003306434A (ja) * 2002-04-15 2003-10-28 Mitsuo Okano 心筋細胞シートによる心筋症治療薬
JP2004267562A (ja) * 2003-03-10 2004-09-30 Advance Co Ltd 生体用担体及び細胞培養方法
JP2006223106A (ja) * 2005-02-15 2006-08-31 Fuji Photo Film Co Ltd 細胞培養担体
WO2006093153A1 (ja) * 2005-02-28 2006-09-08 Cellseed Inc. 培養細胞シート、製造方法及びその利用した組織修復方法
JP2007528755A (ja) * 2003-08-01 2007-10-18 株式会社カルディオ 三次元組織構造体
JPWO2005103233A1 (ja) * 2004-04-25 2008-03-13 株式会社セルシード 培養歯根膜細胞シート、製造方法及びその利用方法
JP2008231083A (ja) * 2007-03-19 2008-10-02 Cellseed Inc 移植用成熟誘導化樹状細胞、製造方法及びその利用方法
WO2008143149A1 (ja) 2007-05-11 2008-11-27 Dai Nippon Printing Co., Ltd. 寸法が保持された細胞シート、その製造方法、及びそのための細胞培養担体
JP2009525144A (ja) * 2006-02-03 2009-07-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ ポリマー薄膜上の設計された細胞増殖およびその生物工学的応用
JP2010130966A (ja) * 2008-12-05 2010-06-17 Tokyo Medical & Dental Univ 心筋毒性検査装置、心筋毒性検査チップおよび心筋毒性検査方法。
WO2010101225A1 (ja) 2009-03-04 2010-09-10 学校法人 東京女子医科大学 細胞シートを利用した細胞評価システム及びその利用方法
JP2011006490A (ja) * 2010-09-27 2011-01-13 Cellseed Inc 心筋細胞シートによる心筋症治療薬
JP2011004750A (ja) * 2000-07-21 2011-01-13 Cellseed Inc 心筋様細胞シート、３次元構造体、心筋様組織及びそれらの製造法
WO2011058813A1 (ja) 2009-11-13 2011-05-19 Sawa Yoshiki 心筋再生用細胞シート、製造方法及びその利用方法
WO2011067983A1 (ja) 2009-12-03 2011-06-09 株式会社セルシード 脂肪細胞シート、その三次元構造体、及びそれらの製造方法
WO2012036224A1 (ja) 2010-09-14 2012-03-22 学校法人 東京女子医科大学 細胞シート積層化物の製造方法、それより得られる血管網を有する細胞シート積層化物及びその利用方法
WO2012036225A1 (ja) 2010-09-14 2012-03-22 学校法人 東京女子医科大学 細胞シート積層化物の製造方法、それより得られる血管網を有する細胞シート積層化物及びその利用方法
WO2012133900A1 (ja) 2011-03-31 2012-10-04 株式会社セルシード 細胞シート移植治具及びその利用方法
WO2012133945A1 (ja) 2011-03-30 2012-10-04 学校法人東京女子医科大学 胚性幹細胞から心筋シートを製造する方法
US8500822B2 (en) 2004-06-01 2013-08-06 Dai Nippon Printing Co., Ltd. Artificial tissue construct and method for producing the same
WO2013137491A1 (ja) 2012-03-15 2013-09-19 国立大学法人京都大学 人工多能性幹細胞から心筋および血管系混合細胞群を製造する方法
WO2013179913A1 (ja) * 2012-05-31 2013-12-05 株式会社ジャパン・ティッシュ・エンジニアリング 培養皿及び培養キット
JP2015070804A (ja) * 2013-10-02 2015-04-16 テルモ株式会社 シート状細胞培養物の剥離方法および製造方法ならびにこれらに用いる容器
JP5786146B2 (ja) * 2007-06-08 2015-09-30 安田　賢二 モデル細胞チップ、モデル細胞チップによる薬効評価装置、および薬効評価方法
WO2017146124A1 (ja) 2016-02-22 2017-08-31 国立大学法人大阪大学 立体的細胞組織の製造方法
US10646211B2 (en) 2016-02-08 2020-05-12 Terumo Kabushiki Kaisha Treatment method and medical device
DE112022001103T5 (de) 2021-02-17 2024-02-22 Fukuoka University Zellblattträger, Zellblattlaminate und Verfahren zu deren Herstellung

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Publication number Priority date Publication date Assignee Title
WO2002010349A1 (en) 2000-07-21 2002-02-07 Cellseed Inc. Cultured epidermal cell sheet, laminated cultured skin sheet and process for producing the same
ES2538696T3 (es) 2003-02-06 2015-06-23 Cellseed Inc. Láminas de células para la formación de la ectocórnea, método para producir las mismas y método para usar las mismas
WO2004069988A1 (ja) * 2003-02-06 2004-08-19 Cellseed Inc. 高密度細胞アレイ用基板、製造法、及びその利用方法
KR101508772B1 (ko) * 2003-02-06 2015-04-14 가부시키가이샤 셀시드 전안부 관련 세포 시트, 3 차원 구조체, 및 그들의 제조법
US9981064B2 (en) * 2003-02-20 2018-05-29 Cellseed Inc. Regenerated corneal endothelial cell sheets, processes for producing the same, and methods of using the same
US7875272B2 (en) 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
EP2338980B1 (en) * 2003-06-27 2015-04-22 DePuy Synthes Products, LLC Regeneration and repair of neural tissue using postpartum umbilical cord -derived cells
ES2279445T3 (es) * 2003-07-28 2007-08-16 Medtronic, Inc. Estimulacion del miocardio.
GB0425266D0 (en) * 2004-11-16 2004-12-15 Norton Healthcare Ltd Pharmaceutical manufacturing process
WO2006083394A2 (en) * 2004-12-21 2006-08-10 Ethicon, Inc. Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same
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US9249386B2 (en) * 2005-06-06 2016-02-02 Dai Nippon Printing Co., Ltd. Substrate for cell transfer
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WO2008045506A2 (en) * 2006-10-10 2008-04-17 President And Fellows Of Harvard College Biopolymer structures
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JP6459458B2 (ja) * 2014-03-03 2019-01-30 ソニー株式会社 細胞評価装置
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JP7130198B2 (ja) * 2017-06-29 2022-09-05 日本光電工業株式会社 積層化細胞シートの製造方法、及びそれにより作製される積層化細胞シート
US11111611B2 (en) 2017-06-30 2021-09-07 Board Of Regents, The University Of Texas System Electrospun PNIPAAm/PCL fiber mats for aligned cell sheets
US11629318B2 (en) 2017-10-20 2023-04-18 President And Fellows Of Harvard College Methods for producing mature adipocytes and methods of use thereof
CN112657051B (zh) * 2020-12-25 2023-08-04 上海交通大学医学院附属上海儿童医学中心 一种基于共轭同轴静电纺丝技术的生物型心室辅助泵及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981001416A1 (en) * 1979-11-14 1981-05-28 Massachusetts Inst Technology Transplantable sheets of living keratinous tissue
JPH02211865A (ja) 1989-02-10 1990-08-23 Kao Corp 細胞培養支持体材料
JPH05192138A (ja) 1992-01-22 1993-08-03 Kao Corp 皮膚細胞培養法及び培養皮膚

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2549151B2 (ja) 1988-07-13 1996-10-30 株式会社東芝 マンコンベヤ
US5543318A (en) * 1991-06-12 1996-08-06 Smith; David A. Method of isolation, culture and proliferation of human atrial myocytes
US6099832A (en) * 1997-05-28 2000-08-08 Genzyme Corporation Transplants for myocardial scars
JP2000023191A (ja) 1998-06-30 2000-01-21 Aqueous Reserch:Kk 動画像圧縮装置
DE60143892D1 (de) * 2000-07-21 2011-03-03 Cellseed Ind Herzmuskel-ähnliche zellschicht, dreidimensionales konstrukt, herzmuskel-ähnliches gewebe und verfahren zur herstellung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981001416A1 (en) * 1979-11-14 1981-05-28 Massachusetts Inst Technology Transplantable sheets of living keratinous tissue
JPH02211865A (ja) 1989-02-10 1990-08-23 Kao Corp 細胞培養支持体材料
JPH05192138A (ja) 1992-01-22 1993-08-03 Kao Corp 皮膚細胞培養法及び培養皮膚

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
AKIHIKO KIKUCHI ET AL.: "Two-dimensional manipulation of confluently cultured vascular endothelial cells using temperature-responsive poly(N-isoptopylacrylamide)-grafted surfaces", JOURNAL OF BIOMATERIALS SCIENCE POLYMER EDITION, vol. 9, no. 12, 1998, pages 1331 - 1348, XP002947553 *
CARDIOVASC. RES., vol. 41, 1999, pages 641
CARRIER ET AL., BIOTECHNOL. BIOENG., vol. 64, 1999, pages 580 - 589
DATABASE BIOSIS [online] TATSUYA SHIMIZU ET AL.: "Two-dimensional manipulation of cardiac myocyte sheets utilizing temperature-responsive culture dishes augments the pulsatile amplitude", XP002947551, accession no. Dialog Database accession no. 200100276118 *
ESCHENHAGEN ET AL., FASEB. J., vol. 11, 1997, pages 683 - 694
KIYOTA GOSHIMA: "Shinkin baiyou-hou no hatten, genjou, mirai, junkan seigyo", CIRC. CONTR., vol. 14, no. 4, 30 December 1993 (1993-12-30), pages 495 - 500, XP002947549 *
LI ET AL., J. THORAC. CARDIOVASC. SURG., vol. 119, 2000, pages 368 - 375
MASAYUKI YAMATO ET AL.: "Ondo outou-sei baiyo-sara kara hi-shinshuu-teki ni kaishuu shita saibou sheet no seika-teki kaiseki to soshiki kougaku e no ouyou", TOKYO JOSHI IKA DAIGAKU SOUGOU KENKYUSHO KIYOU, vol. 19, 1998, pages 173 - 174, XP002947550 *
TATSUYA SIMIZU: "Cardiac tissue engineering-biomaterial wo mochiita shinkin soshiki no kouchiku", IGAKU NO AYUMI, vol. 195, no. 3, 21 October 2000 (2000-10-21), pages 203 - 204, XP002947552 *
TISSUE ENGINEERING, vol. 7, no. 2, April 2001 (2001-04-01), pages 141 - 151 *

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JP2011004750A (ja) * 2000-07-21 2011-01-13 Cellseed Inc 心筋様細胞シート、３次元構造体、心筋様組織及びそれらの製造法
JP2003306434A (ja) * 2002-04-15 2003-10-28 Mitsuo Okano 心筋細胞シートによる心筋症治療薬
JP2004267562A (ja) * 2003-03-10 2004-09-30 Advance Co Ltd 生体用担体及び細胞培養方法
JP2010029680A (ja) * 2003-08-01 2010-02-12 Cellseed Inc 三次元組織構造体
US9587222B2 (en) 2003-08-01 2017-03-07 Cellseed Inc. Three-dimensional tissue structure
JP2012139541A (ja) * 2003-08-01 2012-07-26 Cellseed Inc 三次元組織構造体
JP2007528755A (ja) * 2003-08-01 2007-10-18 株式会社カルディオ 三次元組織構造体
JP2015033637A (ja) * 2003-08-01 2015-02-19 株式会社セルシード 三次元組織構造体
JP4827729B2 (ja) * 2004-04-25 2011-11-30 株式会社セルシード 培養歯根膜細胞シート、製造方法及びその利用方法
JP2011115604A (ja) * 2004-04-25 2011-06-16 Cellseed Inc 培養歯根膜細胞シート、製造方法及びその利用方法
JP2014030430A (ja) * 2004-04-25 2014-02-20 Cellseed Inc 培養歯根膜細胞シート、製造方法及びその利用方法
JPWO2005103233A1 (ja) * 2004-04-25 2008-03-13 株式会社セルシード 培養歯根膜細胞シート、製造方法及びその利用方法
JP2016182137A (ja) * 2004-04-25 2016-10-20 株式会社セルシード 培養歯根膜細胞シート、製造方法及びその利用方法
US8500822B2 (en) 2004-06-01 2013-08-06 Dai Nippon Printing Co., Ltd. Artificial tissue construct and method for producing the same
US9034648B2 (en) 2004-06-01 2015-05-19 Dai Nippon Printing Co., Ltd. Artificial tissue construct and method for producing the same
JP2006223106A (ja) * 2005-02-15 2006-08-31 Fuji Photo Film Co Ltd 細胞培養担体
US9889228B2 (en) 2005-02-28 2018-02-13 Cellseed Inc. Cultured cell sheet, production method, and tissue repair method using thereof
WO2006093153A1 (ja) * 2005-02-28 2006-09-08 Cellseed Inc. 培養細胞シート、製造方法及びその利用した組織修復方法
JP2009525144A (ja) * 2006-02-03 2009-07-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ ポリマー薄膜上の設計された細胞増殖およびその生物工学的応用
JP2008231083A (ja) * 2007-03-19 2008-10-02 Cellseed Inc 移植用成熟誘導化樹状細胞、製造方法及びその利用方法
WO2008143149A1 (ja) 2007-05-11 2008-11-27 Dai Nippon Printing Co., Ltd. 寸法が保持された細胞シート、その製造方法、及びそのための細胞培養担体
EP2626413A1 (en) 2007-05-11 2013-08-14 Dai Nippon Printing Co., Ltd. Cell sheet having good dimensional stability, method for production thereof, and cell culture carrier for use in the method
JP5786146B2 (ja) * 2007-06-08 2015-09-30 安田　賢二 モデル細胞チップ、モデル細胞チップによる薬効評価装置、および薬効評価方法
JP2010130966A (ja) * 2008-12-05 2010-06-17 Tokyo Medical & Dental Univ 心筋毒性検査装置、心筋毒性検査チップおよび心筋毒性検査方法。
US8877457B2 (en) 2008-12-05 2014-11-04 National University Corporation Tokyo Medical And Dental University Device for examining myocardial toxicity, chip for examining myocardial toxicity and method for examining myocardial toxicity
WO2010101225A1 (ja) 2009-03-04 2010-09-10 学校法人 東京女子医科大学 細胞シートを利用した細胞評価システム及びその利用方法
WO2011058813A1 (ja) 2009-11-13 2011-05-19 Sawa Yoshiki 心筋再生用細胞シート、製造方法及びその利用方法
WO2011067983A1 (ja) 2009-12-03 2011-06-09 株式会社セルシード 脂肪細胞シート、その三次元構造体、及びそれらの製造方法
WO2012036224A1 (ja) 2010-09-14 2012-03-22 学校法人 東京女子医科大学 細胞シート積層化物の製造方法、それより得られる血管網を有する細胞シート積層化物及びその利用方法
US9617519B2 (en) 2010-09-14 2017-04-11 Tokyo Women's Medical University Method for manufacturing multilayered cell sheet, multilayered cell sheet having vascular network obtained thereby, and method of use thereof
US9289454B2 (en) 2010-09-14 2016-03-22 Tokyo Women's Medical University Method for manufacturing multilayered cell sheet, multilayered cell sheet having vascular network obtained thereby, and method of use thereof
WO2012036225A1 (ja) 2010-09-14 2012-03-22 学校法人 東京女子医科大学 細胞シート積層化物の製造方法、それより得られる血管網を有する細胞シート積層化物及びその利用方法
JP2011006490A (ja) * 2010-09-27 2011-01-13 Cellseed Inc 心筋細胞シートによる心筋症治療薬
US9623052B2 (en) 2011-03-30 2017-04-18 Tokyo Women's Medical University Method for producing myocardial sheet from embryonic stem cell
WO2012133945A1 (ja) 2011-03-30 2012-10-04 学校法人東京女子医科大学 胚性幹細胞から心筋シートを製造する方法
WO2012133900A1 (ja) 2011-03-31 2012-10-04 株式会社セルシード 細胞シート移植治具及びその利用方法
WO2013137491A1 (ja) 2012-03-15 2013-09-19 国立大学法人京都大学 人工多能性幹細胞から心筋および血管系混合細胞群を製造する方法
US9764063B2 (en) 2012-03-15 2017-09-19 Iheart Japan Corporation Method for producing mixed cell population of cardiomyocytes and vascular cells from induced pluripotent stem cell
WO2013179913A1 (ja) * 2012-05-31 2013-12-05 株式会社ジャパン・ティッシュ・エンジニアリング 培養皿及び培養キット
JP2013247909A (ja) * 2012-05-31 2013-12-12 Japan Tissue Engineering:Kk 培養皿及び培養キット
JP2015070804A (ja) * 2013-10-02 2015-04-16 テルモ株式会社 シート状細胞培養物の剥離方法および製造方法ならびにこれらに用いる容器
US10646211B2 (en) 2016-02-08 2020-05-12 Terumo Kabushiki Kaisha Treatment method and medical device
WO2017146124A1 (ja) 2016-02-22 2017-08-31 国立大学法人大阪大学 立体的細胞組織の製造方法
EP4349972A2 (en) 2016-02-22 2024-04-10 Osaka University Method for producing three-dimensional cell tissue
DE112022001103T5 (de) 2021-02-17 2024-02-22 Fukuoka University Zellblattträger, Zellblattlaminate und Verfahren zu deren Herstellung

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DE60143892D1 (de) 2011-03-03
US20040009566A1 (en) 2004-01-15
JP4679795B2 (ja) 2011-04-27
EP1302535B1 (en) 2011-01-19
JP2011004750A (ja) 2011-01-13
ES2357764T3 (es) 2011-04-29
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EP2275532A1 (en) 2011-01-19
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