DE60143892D1 - Herzmuskel-ähnliche zellschicht, dreidimensionales konstrukt, herzmuskel-ähnliches gewebe und verfahren zur herstellung - Google Patents

Herzmuskel-ähnliche zellschicht, dreidimensionales konstrukt, herzmuskel-ähnliches gewebe und verfahren zur herstellung

Info

Publication number
DE60143892D1
DE60143892D1 DE60143892T DE60143892T DE60143892D1 DE 60143892 D1 DE60143892 D1 DE 60143892D1 DE 60143892 T DE60143892 T DE 60143892T DE 60143892 T DE60143892 T DE 60143892T DE 60143892 D1 DE60143892 D1 DE 60143892D1
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DE
Germany
Prior art keywords
similar
heart
manufacture
cell layer
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60143892T
Other languages
English (en)
Inventor
Teruo Okano
Tatsuya Shimizu
Masayuki Yamato
Akihiko Kikuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CELLSEED IND
Original Assignee
CELLSEED IND
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CELLSEED IND filed Critical CELLSEED IND
Application granted granted Critical
Publication of DE60143892D1 publication Critical patent/DE60143892D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/383—Nerve cells, e.g. dendritic cells, Schwann cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3826—Muscle cells, e.g. smooth muscle cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2539/00—Supports and/or coatings for cell culture characterised by properties
    • C12N2539/10—Coating allowing for selective detachment of cells, e.g. thermoreactive coating
DE60143892T 2000-07-21 2001-07-02 Herzmuskel-ähnliche zellschicht, dreidimensionales konstrukt, herzmuskel-ähnliches gewebe und verfahren zur herstellung Expired - Lifetime DE60143892D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000221385 2000-07-21
PCT/JP2001/005722 WO2002008387A1 (fr) 2000-07-21 2001-07-02 Feuille cellulaire du type muscle cardiaque, construction tridimensionnelle, tissu du type muscle cardiaque et procede de production associe

Publications (1)

Publication Number Publication Date
DE60143892D1 true DE60143892D1 (de) 2011-03-03

Family

ID=18715796

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60143892T Expired - Lifetime DE60143892D1 (de) 2000-07-21 2001-07-02 Herzmuskel-ähnliche zellschicht, dreidimensionales konstrukt, herzmuskel-ähnliches gewebe und verfahren zur herstellung

Country Status (7)

Country Link
US (1) US20040009566A1 (de)
EP (2) EP2275532B1 (de)
JP (2) JP4679795B2 (de)
AT (1) ATE495766T1 (de)
DE (1) DE60143892D1 (de)
ES (2) ES2385301T3 (de)
WO (1) WO2002008387A1 (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002010349A1 (en) 2000-07-21 2002-02-07 Cellseed Inc. Cultured epidermal cell sheet, laminated cultured skin sheet and process for producing the same
EP2275532B1 (de) * 2000-07-21 2012-06-06 Cellseed Inc. Herzmuskel-ähnliche Zellschicht und Verfahren zur Herstellung
JP5226923B2 (ja) * 2002-04-15 2013-07-03 株式会社セルシード 心筋細胞シートによる心筋症治療薬
EP2450065B1 (de) 2003-02-06 2017-08-23 CellSeed Inc. Zellblätter zur Hornhautepithelbildung, Verfahren zu deren Herstellung und Verwendungsverfahren dafür
KR101508772B1 (ko) * 2003-02-06 2015-04-14 가부시키가이샤 셀시드 전안부 관련 세포 시트, 3 차원 구조체, 및 그들의 제조법
AU2003207285A1 (en) * 2003-02-06 2004-08-30 Cellseed Inc. High-density cell array board, process for producing the same and method of using the same
EP1600177B1 (de) * 2003-02-20 2016-05-25 Cellseed Inc. Endothelzellen-scheibe für die hornhautregeneration, verfahren zur herstellung der scheibe und anwendungsverfahren dafür
JP4756816B2 (ja) * 2003-03-10 2011-08-24 株式会社アドバンス 骨再生補綴物の製造方法
AU2004252567B2 (en) * 2003-06-27 2011-10-06 Ethicon, Incorporated Repair and regeneration of ocular tissue using postpartum-derived cells
US7875272B2 (en) 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
DE602004004541T2 (de) * 2003-07-28 2007-11-22 Medtronic, Inc., Minneapolis Myokard-stimulation
WO2005011524A1 (en) 2003-08-01 2005-02-10 Cardio Incorporated Three-dimentional tissue structure
US9114192B2 (en) * 2004-04-25 2015-08-25 Cellseed Inc. Cultured periodontal ligament cell sheet, process for producing the same and method of use thereof
JP4303643B2 (ja) 2004-06-01 2009-07-29 育男 森田 人工組織体およびその製造方法
GB0425266D0 (en) * 2004-11-16 2004-12-15 Norton Healthcare Ltd Pharmaceutical manufacturing process
US20060171930A1 (en) * 2004-12-21 2006-08-03 Agnieszka Seyda Postpartum cells derived from umbilical cord tissue, and methods of making, culturing, and using the same
WO2006083394A2 (en) * 2004-12-21 2006-08-10 Ethicon, Inc. Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same
CA2589041C (en) 2004-12-23 2019-08-20 Ethicon, Incorporated Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
JP2006223106A (ja) * 2005-02-15 2006-08-31 Fuji Photo Film Co Ltd 細胞培養担体
WO2006093153A1 (ja) 2005-02-28 2006-09-08 Cellseed Inc. 培養細胞シート、製造方法及びその利用した組織修復方法
ES2693609T3 (es) * 2005-02-28 2018-12-12 Cellseed Inc. Lámina de células cultivadas, método para su producción y método para su aplicación
EP1728856B1 (de) 2005-06-01 2009-05-13 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur optischen Bestimmung des dynamischen Verhaltens von kontrahierenden Zellen
US9249386B2 (en) * 2005-06-06 2016-02-02 Dai Nippon Printing Co., Ltd. Substrate for cell transfer
WO2007050314A2 (en) * 2005-10-24 2007-05-03 Hosheng Tu Medical device with living cell sheet
AU2007309701B2 (en) * 2006-02-03 2012-09-27 President And Fellows Of Harvard College Engineered cell growth on polymeric films and biotechnological applications there of
US20100196432A1 (en) * 2006-10-10 2010-08-05 Feinberg Adam W Biopolymer structures
JP5424538B2 (ja) * 2007-03-19 2014-02-26 株式会社セルシード 移植用成熟誘導化樹状細胞、製造方法及びその利用方法
EP2151492B1 (de) 2007-05-11 2015-03-04 Dai Nippon Printing Co., Ltd. Zellschicht mit guter dimensionaler stabilität, verfahren zu ihrer herstellung und zellkulturträger zur verwendung für das verfahren
EP2157166B1 (de) * 2007-06-08 2015-05-06 Kenji Yasuda Modellzellenchip, vorrichtung zur beurteilung des arzneimitteleffektes unter verwendung des modellzellenchips und verfahren zur beurteilung des arzneimitteleffektes
WO2009085067A2 (en) * 2007-09-26 2009-07-09 President And Fellows Of Harvard College Boundary conditions for the arrangement of cells and tissues
US8748181B2 (en) * 2008-05-23 2014-06-10 President And Fellows Of Harvard College Methods of generating patterned soft substrates and uses thereof
US9598668B2 (en) * 2008-10-14 2017-03-21 Cellseed Inc. Temperature-responsive cell culture substrate and method for producing the same
JP5614928B2 (ja) 2008-12-05 2014-10-29 国立大学法人 東京医科歯科大学 心筋毒性検査装置、心筋毒性検査チップおよび心筋毒性検査方法
US20100166822A1 (en) * 2008-12-31 2010-07-01 Howmedica Osteonics Corp. Adhesive cartilage implant
EP2404992A4 (de) 2009-03-04 2012-09-05 Univ Tokyo Womens Medical Zelluntersuchungssystem mit zellblatt und verwendungsverfahren dafür
US9012172B2 (en) 2009-05-01 2015-04-21 President And Fellows Of Harvard College Devices comprising muscle thin films and uses thereof in high throughput assays for determining contractile function
JPWO2011058813A1 (ja) 2009-11-13 2013-03-28 芳樹 澤 心筋再生用細胞シート、製造方法及びその利用方法
JP5661048B2 (ja) 2009-12-03 2015-01-28 株式会社セルシード 脂肪細胞シート、その三次元構造体、及びそれらの製造方法
WO2012006320A1 (en) 2010-07-06 2012-01-12 President And Fellows Of Harvard College Photosensitive cardiac rhythm modulation systems
US9289454B2 (en) 2010-09-14 2016-03-22 Tokyo Women's Medical University Method for manufacturing multilayered cell sheet, multilayered cell sheet having vascular network obtained thereby, and method of use thereof
WO2012036225A1 (ja) 2010-09-14 2012-03-22 学校法人 東京女子医科大学 細胞シート積層化物の製造方法、それより得られる血管網を有する細胞シート積層化物及びその利用方法
JP5367672B2 (ja) * 2010-09-27 2013-12-11 株式会社セルシード 心筋細胞シートによる心筋症治療薬
JP5370376B2 (ja) 2011-01-13 2013-12-18 横河電機株式会社 機器情報表示装置、機器情報表示プログラム、及び記録媒体
JP5840855B2 (ja) 2011-03-30 2016-01-06 学校法人東京女子医科大学 胚性幹細胞から心筋シートを製造する方法
JP5816452B2 (ja) 2011-03-31 2015-11-18 株式会社セルシード 細胞シート移植治具及びその利用方法
WO2013086512A2 (en) 2011-12-09 2013-06-13 President And Fellows Of Harvard College Muscle chips and methods of use thereof
EP2826855B1 (de) 2012-03-15 2018-08-29 iHeart Japan Corporation Myocardiale zellschicht
JP5990403B2 (ja) * 2012-05-31 2016-09-14 株式会社 ジャパン・ティッシュ・エンジニアリング 培養皿及び培養キット
WO2014015251A2 (en) 2012-07-20 2014-01-23 President And Fellows Of Harvard College Tissue-engineered pumps and valves and uses thereof
JP6301098B2 (ja) * 2013-10-02 2018-03-28 テルモ株式会社 シート状細胞培養物の剥離方法および製造方法ならびにこれらに用いる容器
WO2015178980A2 (en) 2014-02-18 2015-11-26 President And Fellows Of Harvard College Anisotropic muscular tissue devices with integrated electrical force readouts
JP6459458B2 (ja) * 2014-03-03 2019-01-30 ソニー株式会社 細胞評価装置
EP3162385B1 (de) 2014-06-24 2019-12-11 Washio, Kaoru Kultivierter periodontaler ligamentzellschichtkomplex für implantat
US10997871B2 (en) 2014-09-24 2021-05-04 President And Fellows Of Harvard College Contractile function measuring devices, systems, and methods of use thereof
WO2017087759A1 (en) 2015-11-18 2017-05-26 President And Fellows Of Harvard College Cartridge-based system for long term culture of cell clusters
JP2017140109A (ja) 2016-02-08 2017-08-17 テルモ株式会社 治療方法および医療用装置
CN108699512A (zh) 2016-02-22 2018-10-23 国立大学法人大阪大学 立体细胞组织的制造方法
JP7130198B2 (ja) * 2017-06-29 2022-09-05 日本光電工業株式会社 積層化細胞シートの製造方法、及びそれにより作製される積層化細胞シート
US11111611B2 (en) 2017-06-30 2021-09-07 Board Of Regents, The University Of Texas System Electrospun PNIPAAm/PCL fiber mats for aligned cell sheets
US11629318B2 (en) 2017-10-20 2023-04-18 President And Fellows Of Harvard College Methods for producing mature adipocytes and methods of use thereof
CN112657051B (zh) * 2020-12-25 2023-08-04 上海交通大学医学院附属上海儿童医学中心 一种基于共轭同轴静电纺丝技术的生物型心室辅助泵及其制备方法
JPWO2022176855A1 (de) 2021-02-17 2022-08-25

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304866A (en) * 1979-11-14 1981-12-08 Massachusetts Institute Of Technology Transplantable sheets of living keratinous tissue
JP2549151B2 (ja) 1988-07-13 1996-10-30 株式会社東芝 マンコンベヤ
JPH06104061B2 (ja) 1989-02-10 1994-12-21 花王株式会社 細胞培養支持体材料
US5543318A (en) * 1991-06-12 1996-08-06 Smith; David A. Method of isolation, culture and proliferation of human atrial myocytes
JPH05192138A (ja) 1992-01-22 1993-08-03 Kao Corp 皮膚細胞培養法及び培養皮膚
US6099832A (en) * 1997-05-28 2000-08-08 Genzyme Corporation Transplants for myocardial scars
JP2000023191A (ja) 1998-06-30 2000-01-21 Aqueous Reserch:Kk 動画像圧縮装置
EP2275532B1 (de) * 2000-07-21 2012-06-06 Cellseed Inc. Herzmuskel-ähnliche Zellschicht und Verfahren zur Herstellung

Also Published As

Publication number Publication date
ATE495766T1 (de) 2011-02-15
EP1302535A4 (de) 2007-08-29
EP1302535A1 (de) 2003-04-16
ES2357764T3 (es) 2011-04-29
EP1302535B1 (de) 2011-01-19
JP4679795B2 (ja) 2011-04-27
JP2011004750A (ja) 2011-01-13
JPWO2002008387A1 (ja) 2004-02-05
EP2275532A1 (de) 2011-01-19
US20040009566A1 (en) 2004-01-15
ES2385301T3 (es) 2012-07-20
JP5086398B2 (ja) 2012-11-28
EP2275532B1 (de) 2012-06-06
WO2002008387A1 (fr) 2002-01-31

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