UY37574A - Azolopirimidina para el tratamiento de trastornos relacionados con el cáncer - Google Patents

Azolopirimidina para el tratamiento de trastornos relacionados con el cáncer

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Publication number
UY37574A
UY37574A UY0001037574A UY37574A UY37574A UY 37574 A UY37574 A UY 37574A UY 0001037574 A UY0001037574 A UY 0001037574A UY 37574 A UY37574 A UY 37574A UY 37574 A UY37574 A UY 37574A
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UY
Uruguay
Prior art keywords
cancer
treatment
compound
azolopirimidine
related disorders
Prior art date
Application number
UY0001037574A
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English (en)
Inventor
Joel Beatty
Laurent Debien
Jenna Jeffrey
Reddy Leleti Manmohan
Dillon Miles
Jay Powers
Brandon Rosen
Ehesan Sharif
RhiannonThomas-Tran
Debashis Mandal
Original Assignee
Arcus Biosciences Inc
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Publication date
Application filed by Arcus Biosciences Inc filed Critical Arcus Biosciences Inc
Publication of UY37574A publication Critical patent/UY37574A/es

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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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Abstract

En la presente se describe un compuesto que es un inhibidor de al menos uno de los receptores de adenosina A2A y A2B, y composiciones que contienen el compuesto y métodos para sintetizar el compuesto. El uso de tal compuesto y composiciones para el tratamiento de un conjunto diverso de enfermedades, trastornos y afecciones, que incluye trastornos relacionados con cáncer y con inmunidad que se median, al menos en parte, por el receptor de adenosina A2A y/o receptor de adenosina A2B.
UY0001037574A 2017-01-20 2018-01-19 Azolopirimidina para el tratamiento de trastornos relacionados con el cáncer UY37574A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762448608P 2017-01-20 2017-01-20
US201762479005P 2017-03-30 2017-03-30

Publications (1)

Publication Number Publication Date
UY37574A true UY37574A (es) 2018-05-31

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UY0001037574A UY37574A (es) 2017-01-20 2018-01-19 Azolopirimidina para el tratamiento de trastornos relacionados con el cáncer

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US (3) US10399962B2 (es)
EP (2) EP3570844B1 (es)
JP (3) JP6697091B2 (es)
KR (1) KR102611446B1 (es)
CN (2) CN116768859A (es)
AU (2) AU2018210272B2 (es)
BR (1) BR112019014193A2 (es)
CA (1) CA3047600A1 (es)
CL (1) CL2019002003A1 (es)
DK (1) DK3570844T3 (es)
FI (1) FI3570844T3 (es)
HR (1) HRP20231157T1 (es)
HU (1) HUE064141T2 (es)
IL (2) IL267924B (es)
LT (1) LT3570844T (es)
MX (2) MX2019008593A (es)
NZ (1) NZ754731A (es)
PH (1) PH12019501671A1 (es)
PL (1) PL3570844T3 (es)
PT (1) PT3570844T (es)
SG (1) SG11201905812WA (es)
SI (1) SI3570844T1 (es)
TW (2) TWI781136B (es)
UA (1) UA126863C2 (es)
UY (1) UY37574A (es)
WO (1) WO2018136700A1 (es)

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