CR20150664A - Moduladores de los receptores de estrógeno y sus usos - Google Patents
Moduladores de los receptores de estrógeno y sus usosInfo
- Publication number
- CR20150664A CR20150664A CR20150664A CR20150664A CR20150664A CR 20150664 A CR20150664 A CR 20150664A CR 20150664 A CR20150664 A CR 20150664A CR 20150664 A CR20150664 A CR 20150664A CR 20150664 A CR20150664 A CR 20150664A
- Authority
- CR
- Costa Rica
- Prior art keywords
- estrogen
- modulators
- receivers
- compounds
- estrogen receptors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
Abstract
Compuestos que son moduladores de los receptores de estrógeno. Composiciones farmacéuticas y medicamentos que los comprenden. Métodos para usarlos, solos o en combinación con otros compuestos, en el tratamiento de aquellas enfermedades y aquellas afecciones que están mediadas por los receptores de estrógeno o que dependen de los receptores de estrógeno.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361836901P | 2013-06-19 | 2013-06-19 | |
US201461952430P | 2014-03-13 | 2014-03-13 | |
PCT/US2014/043040 WO2014205138A1 (en) | 2013-06-19 | 2014-06-18 | Estrogen receptor modulator and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CR20150664A true CR20150664A (es) | 2016-01-29 |
Family
ID=52105249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR20150664A CR20150664A (es) | 2013-06-19 | 2015-12-16 | Moduladores de los receptores de estrógeno y sus usos |
Country Status (20)
Country | Link |
---|---|
US (2) | US9873684B2 (es) |
EP (1) | EP3010501B1 (es) |
JP (2) | JP6576916B2 (es) |
KR (1) | KR20160021277A (es) |
CN (1) | CN105324115B (es) |
AU (1) | AU2014281511A1 (es) |
BR (1) | BR112015031903A8 (es) |
CA (1) | CA2912853A1 (es) |
CL (1) | CL2015003456A1 (es) |
CR (1) | CR20150664A (es) |
EA (1) | EA031077B1 (es) |
HK (1) | HK1214532A1 (es) |
IL (1) | IL242611B (es) |
MX (1) | MX2015017655A (es) |
PE (1) | PE20160157A1 (es) |
PH (1) | PH12015502621A1 (es) |
SG (1) | SG11201509508YA (es) |
TW (1) | TW201501710A (es) |
UA (1) | UA117249C2 (es) |
WO (1) | WO2014205138A1 (es) |
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US9259399B2 (en) | 2007-11-07 | 2016-02-16 | Cornell University | Targeting CDK4 and CDK6 in cancer therapy |
MX2015016171A (es) | 2013-06-19 | 2016-08-08 | Seragon Pharmaceuticals Inc | Moduladores del receptor de estrogeno de azetidina y usos de los mismos. |
WO2014205138A1 (en) * | 2013-06-19 | 2014-12-24 | Seragon Pharmaceuticals, Inc. | Estrogen receptor modulator and uses thereof |
EP2862880A1 (en) | 2013-10-16 | 2015-04-22 | Solvay Acetow GmbH | Acylation process |
AU2015228859A1 (en) * | 2014-03-13 | 2016-07-07 | F. Hoffmann-La Roche Ag | Therapeutic combinations with estrogen receptor modulators |
CN106488767A (zh) | 2014-03-13 | 2017-03-08 | 豪夫迈·罗氏有限公司 | 调节雌激素受体突变体的方法和组合物 |
WO2015138895A1 (en) | 2014-03-13 | 2015-09-17 | Indiana University Research And Technology Corporation | Hepatitis b core protein allosteric modulators |
WO2016097073A1 (en) * | 2014-12-18 | 2016-06-23 | F. Hoffmann-La Roche Ag | Derivatives of 2,3-diphenylchromene useful for the treatment of cancer |
US9845291B2 (en) | 2014-12-18 | 2017-12-19 | Genentech, Inc. | Estrogen receptor modulators and uses thereof |
RS60824B1 (sr) | 2014-12-18 | 2020-10-30 | Hoffmann La Roche | Tetrahidro-pirido[3,4-b]indoli kao modulatori estrogenih receptora i njihova upotreba |
DK3302471T3 (da) | 2015-05-29 | 2021-11-15 | Eisai R&D Man Co Ltd | Tetrasubstituerede alkenforbindelser og deres anvendelse |
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WO2017182493A1 (en) | 2016-04-20 | 2017-10-26 | Astrazeneca Ab | Indazole derivatives for use in down-regulation of the estrogen receptor for the treatment of cancer |
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JP2019520379A (ja) | 2016-07-01 | 2019-07-18 | ジー1 セラピューティクス, インコーポレイテッド | ピリミジン系の抗増殖剤 |
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US10987360B2 (en) | 2016-09-15 | 2021-04-27 | Assembly Biosciences, Inc. | Hepatitis B core protein modulators |
JP2020011901A (ja) * | 2016-10-20 | 2020-01-23 | 協和キリン株式会社 | ピロリジン化合物の製造方法 |
WO2018081168A2 (en) | 2016-10-24 | 2018-05-03 | The Board Of Trustees Of The University Of Illinois | Benzothiophene-based selective mixed estrogen receptor downregulators |
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WO2014205138A1 (en) * | 2013-06-19 | 2014-12-24 | Seragon Pharmaceuticals, Inc. | Estrogen receptor modulator and uses thereof |
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AU2015228859A1 (en) | 2014-03-13 | 2016-07-07 | F. Hoffmann-La Roche Ag | Therapeutic combinations with estrogen receptor modulators |
WO2016009073A1 (en) | 2014-07-18 | 2016-01-21 | Bottin Hervé | Wall panel connecting system for modular building units |
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US9845291B2 (en) | 2014-12-18 | 2017-12-19 | Genentech, Inc. | Estrogen receptor modulators and uses thereof |
-
2014
- 2014-06-18 WO PCT/US2014/043040 patent/WO2014205138A1/en active Application Filing
- 2014-06-18 EA EA201592214A patent/EA031077B1/ru not_active IP Right Cessation
- 2014-06-18 EP EP14812952.1A patent/EP3010501B1/en active Active
- 2014-06-18 KR KR1020167001338A patent/KR20160021277A/ko not_active Application Discontinuation
- 2014-06-18 SG SG11201509508YA patent/SG11201509508YA/en unknown
- 2014-06-18 PE PE2015002634A patent/PE20160157A1/es unknown
- 2014-06-18 AU AU2014281511A patent/AU2014281511A1/en not_active Abandoned
- 2014-06-18 UA UAA201600246A patent/UA117249C2/uk unknown
- 2014-06-18 JP JP2016521557A patent/JP6576916B2/ja active Active
- 2014-06-18 CA CA2912853A patent/CA2912853A1/en not_active Abandoned
- 2014-06-18 BR BR112015031903A patent/BR112015031903A8/pt not_active Application Discontinuation
- 2014-06-18 CN CN201480035316.2A patent/CN105324115B/zh active Active
- 2014-06-18 MX MX2015017655A patent/MX2015017655A/es unknown
- 2014-06-19 TW TW103121277A patent/TW201501710A/zh unknown
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2015
- 2015-11-16 IL IL242611A patent/IL242611B/en not_active IP Right Cessation
- 2015-11-24 CL CL2015003456A patent/CL2015003456A1/es unknown
- 2015-11-24 PH PH12015502621A patent/PH12015502621A1/en unknown
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2016
- 2016-03-08 HK HK16102620.6A patent/HK1214532A1/zh unknown
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2017
- 2017-06-12 US US15/620,304 patent/US10227334B2/en active Active
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2019
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Also Published As
Publication number | Publication date |
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CL2015003456A1 (es) | 2016-07-29 |
US20160090378A1 (en) | 2016-03-31 |
JP2019142871A (ja) | 2019-08-29 |
TW201501710A (zh) | 2015-01-16 |
EA031077B1 (ru) | 2018-11-30 |
EP3010501B1 (en) | 2021-11-03 |
SG11201509508YA (en) | 2015-12-30 |
US9873684B2 (en) | 2018-01-23 |
MX2015017655A (es) | 2016-04-15 |
KR20160021277A (ko) | 2016-02-24 |
US20170275273A1 (en) | 2017-09-28 |
AU2014281511A1 (en) | 2015-12-03 |
EA201592214A1 (ru) | 2016-06-30 |
PE20160157A1 (es) | 2016-03-18 |
CN105324115B (zh) | 2019-01-04 |
EP3010501A1 (en) | 2016-04-27 |
IL242611B (en) | 2018-10-31 |
US10227334B2 (en) | 2019-03-12 |
CN105324115A (zh) | 2016-02-10 |
WO2014205138A1 (en) | 2014-12-24 |
BR112015031903A8 (pt) | 2019-12-31 |
CA2912853A1 (en) | 2014-12-24 |
BR112015031903A2 (pt) | 2017-07-25 |
UA117249C2 (uk) | 2018-07-10 |
HK1214532A1 (zh) | 2016-07-29 |
PH12015502621A1 (en) | 2016-03-07 |
JP2016523253A (ja) | 2016-08-08 |
EP3010501A4 (en) | 2017-02-01 |
JP6576916B2 (ja) | 2019-09-18 |
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