UY37222A - PROCEDIMIENTO PARA LA PREPARACIÓN DE DERIVADOS DE 1-FENILO-1,2,4-TRIAZOL SUSTITUIDOS POR 5-HIdroxIalQUILO - Google Patents
PROCEDIMIENTO PARA LA PREPARACIÓN DE DERIVADOS DE 1-FENILO-1,2,4-TRIAZOL SUSTITUIDOS POR 5-HIdroxIalQUILOInfo
- Publication number
- UY37222A UY37222A UY0001037222A UY37222A UY37222A UY 37222 A UY37222 A UY 37222A UY 0001037222 A UY0001037222 A UY 0001037222A UY 37222 A UY37222 A UY 37222A UY 37222 A UY37222 A UY 37222A
- Authority
- UY
- Uruguay
- Prior art keywords
- preparation
- triazol
- phenyl
- derivatives
- hydroxyalquyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- CGRLXLHYYDSTKR-UHFFFAOYSA-N 1-phenyl-1H-1,2,4-triazole Chemical class N1=CN=CN1C1=CC=CC=C1 CGRLXLHYYDSTKR-UHFFFAOYSA-N 0.000 title 1
- -1 monofluoromethyl Chemical group 0.000 abstract 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000000068 chlorophenyl group Chemical group 0.000 abstract 1
- 125000001028 difluoromethyl group Chemical group [H]C(F)(F)* 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16168163 | 2016-05-03 | ||
| EP16168166 | 2016-05-03 | ||
| EP16168165 | 2016-05-03 | ||
| EP16168172 | 2016-05-03 | ||
| EP16168169 | 2016-05-03 | ||
| EP17160086 | 2017-03-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY37222A true UY37222A (es) | 2017-11-30 |
Family
ID=58633014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY0001037222A UY37222A (es) | 2016-05-03 | 2017-05-02 | PROCEDIMIENTO PARA LA PREPARACIÓN DE DERIVADOS DE 1-FENILO-1,2,4-TRIAZOL SUSTITUIDOS POR 5-HIdroxIalQUILO |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US10703742B2 (enExample) |
| EP (1) | EP3452467A1 (enExample) |
| JP (2) | JP6921863B2 (enExample) |
| KR (1) | KR20190003536A (enExample) |
| CN (2) | CN109071500B (enExample) |
| AU (2) | AU2017259872B2 (enExample) |
| BR (1) | BR112018072528A2 (enExample) |
| CA (1) | CA3022789A1 (enExample) |
| CL (1) | CL2018003107A1 (enExample) |
| CO (1) | CO2018011948A2 (enExample) |
| IL (1) | IL262534B (enExample) |
| JO (1) | JOP20170103A1 (enExample) |
| MX (2) | MX391356B (enExample) |
| PE (1) | PE20190202A1 (enExample) |
| RU (1) | RU2742885C2 (enExample) |
| SG (1) | SG11201809672YA (enExample) |
| TW (1) | TWI755393B (enExample) |
| UY (1) | UY37222A (enExample) |
| WO (1) | WO2017191104A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20170103A1 (ar) * | 2016-05-03 | 2017-11-03 | Bayer Pharma AG | عملية لتحضير مشتقات 1-فنيل-1، 2، 4-تريازول مستبدلة بـ 5-هيدروكسي ألكيل |
| JP6911052B2 (ja) * | 2016-05-03 | 2021-07-28 | バイエル ファーマ アクチエンゲゼルシャフト | オキソアルキル置換フェニルトリアゾール誘導体およびその使用 |
| US9988367B2 (en) * | 2016-05-03 | 2018-06-05 | Bayer Pharma Aktiengesellschaft | Amide-substituted pyridinyltriazole derivatives and uses thereof |
| WO2021259852A1 (en) | 2020-06-25 | 2021-12-30 | Bayer Aktiengesellschaft | Process for preparing 5-(alkoxycarbonyl)-and 5-(carboxamide)-1-aryl-1,2,4-triazole derivatives |
| CN118894815A (zh) * | 2024-07-12 | 2024-11-05 | 西北师范大学 | 一种含三氟甲基的1,2,4-三氮唑啉类衍生物及其制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI490212B (zh) * | 2006-05-25 | 2015-07-01 | Synta Pharmaceuticals Corp | 調節ｈｓｐ９０活性之三唑化合物 |
| WO2010033626A1 (en) * | 2008-09-19 | 2010-03-25 | Institute For Oneworld Health | Compounds, compositions and methods comprising imidazole and triazole derivatives |
| DE102010001064A1 (de) * | 2009-03-18 | 2010-09-23 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 2-Acetamido-5-Aryl-1,2,4-triazolone und deren Verwendung |
| PL2539326T3 (pl) * | 2010-02-27 | 2017-10-31 | Bayer Ip Gmbh | Połączone bis-arylem arylotriazolony i ich zastosowanie |
| AU2013258107B2 (en) * | 2012-05-08 | 2017-06-22 | Bayer Pharma Aktiengesellschaft | Method for the preparation of triazole compounds |
| KR20170081178A (ko) * | 2014-11-03 | 2017-07-11 | 바이엘 파마 악티엔게젤샤프트 | 히드록시알킬-치환된 페닐트리아졸 유도체 및 그의 용도 |
| JOP20170103A1 (ar) * | 2016-05-03 | 2017-11-03 | Bayer Pharma AG | عملية لتحضير مشتقات 1-فنيل-1، 2، 4-تريازول مستبدلة بـ 5-هيدروكسي ألكيل |
| JP6911052B2 (ja) * | 2016-05-03 | 2021-07-28 | バイエル ファーマ アクチエンゲゼルシャフト | オキソアルキル置換フェニルトリアゾール誘導体およびその使用 |
| US9988367B2 (en) * | 2016-05-03 | 2018-06-05 | Bayer Pharma Aktiengesellschaft | Amide-substituted pyridinyltriazole derivatives and uses thereof |
-
2017
- 2017-05-01 JO JOJO/P/2017/0103A patent/JOP20170103A1/ar unknown
- 2017-05-02 CN CN201780027607.0A patent/CN109071500B/zh not_active Expired - Fee Related
- 2017-05-02 RU RU2018142264A patent/RU2742885C2/ru active
- 2017-05-02 CN CN202110424553.XA patent/CN113105403A/zh active Pending
- 2017-05-02 TW TW106114435A patent/TWI755393B/zh not_active IP Right Cessation
- 2017-05-02 MX MX2020010365A patent/MX391356B/es unknown
- 2017-05-02 US US16/098,238 patent/US10703742B2/en not_active Expired - Fee Related
- 2017-05-02 WO PCT/EP2017/060367 patent/WO2017191104A1/de not_active Ceased
- 2017-05-02 UY UY0001037222A patent/UY37222A/es not_active Application Discontinuation
- 2017-05-02 CA CA3022789A patent/CA3022789A1/en active Pending
- 2017-05-02 EP EP17719636.7A patent/EP3452467A1/de not_active Withdrawn
- 2017-05-02 JP JP2018557408A patent/JP6921863B2/ja not_active Expired - Fee Related
- 2017-05-02 AU AU2017259872A patent/AU2017259872B2/en not_active Ceased
- 2017-05-02 MX MX2018013336A patent/MX379555B/es unknown
- 2017-05-02 PE PE2018002254A patent/PE20190202A1/es unknown
- 2017-05-02 SG SG11201809672YA patent/SG11201809672YA/en unknown
- 2017-05-02 BR BR112018072528-5A patent/BR112018072528A2/pt active Search and Examination
- 2017-05-02 KR KR1020187031568A patent/KR20190003536A/ko not_active Ceased
-
2018
- 2018-10-23 IL IL262534A patent/IL262534B/en active IP Right Grant
- 2018-10-31 CL CL2018003107A patent/CL2018003107A1/es unknown
- 2018-11-02 CO CONC2018/0011948A patent/CO2018011948A2/es unknown
-
2020
- 2020-05-21 US US16/880,933 patent/US20200299271A1/en not_active Abandoned
-
2021
- 2021-06-14 JP JP2021098486A patent/JP2021143193A/ja not_active Withdrawn
- 2021-09-22 AU AU2021236502A patent/AU2021236502A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20230612 |