UY37222A - PROCEDIMIENTO PARA LA PREPARACIÓN DE DERIVADOS DE 1-FENILO-1,2,4-TRIAZOL SUSTITUIDOS POR 5-HIdroxIalQUILO - Google Patents
PROCEDIMIENTO PARA LA PREPARACIÓN DE DERIVADOS DE 1-FENILO-1,2,4-TRIAZOL SUSTITUIDOS POR 5-HIdroxIalQUILOInfo
- Publication number
- UY37222A UY37222A UY0001037222A UY37222A UY37222A UY 37222 A UY37222 A UY 37222A UY 0001037222 A UY0001037222 A UY 0001037222A UY 37222 A UY37222 A UY 37222A UY 37222 A UY37222 A UY 37222A
- Authority
- UY
- Uruguay
- Prior art keywords
- preparation
- triazol
- phenyl
- derivatives
- hydroxyalquyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Abstract
La presente solicitud se refiere a un procedimiento novedoso y mejorado para la preparación de derivados de 5-(hidroxialquilo)-1-fenilo-1,2,4-triazol de la fórmula (I) en la que R1A y R1B se seleccionan independientemente del grupo que consiste en hidrógeno, flúor, cloro, metilo, monofluormetilo, difluormetilo, trifluormetilo, etilo, metoxi, difluormetoxi y trifluormetoxi, nuevas fases previas para su preparación y la preparación y el uso de la modificación cristalina I de (5-(4- 10 clorofenil)-2-({1-(3-clorofenil)-5-[(1S)-1-hidroxietil]-1H-1,2,4-triazol-3-ilo}metilo)-4-[(2S)-3,3,3-trifluor- 2-hidroxipropil]-2,4-dihidro-3H-1,2,4-triazol-3-ona de la fórmula (I-A-1).
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16168169 | 2016-05-03 | ||
EP16168165 | 2016-05-03 | ||
EP16168163 | 2016-05-03 | ||
EP16168166 | 2016-05-03 | ||
EP16168172 | 2016-05-03 | ||
EP17160086 | 2017-03-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY37222A true UY37222A (es) | 2017-11-30 |
Family
ID=58633014
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY0001037222A UY37222A (es) | 2016-05-03 | 2017-05-02 | PROCEDIMIENTO PARA LA PREPARACIÓN DE DERIVADOS DE 1-FENILO-1,2,4-TRIAZOL SUSTITUIDOS POR 5-HIdroxIalQUILO |
Country Status (18)
Country | Link |
---|---|
US (2) | US10703742B2 (es) |
EP (1) | EP3452467A1 (es) |
JP (2) | JP6921863B2 (es) |
KR (1) | KR20190003536A (es) |
CN (2) | CN109071500B (es) |
AU (2) | AU2017259872B2 (es) |
BR (1) | BR112018072528A2 (es) |
CA (1) | CA3022789A1 (es) |
CL (1) | CL2018003107A1 (es) |
CO (1) | CO2018011948A2 (es) |
IL (1) | IL262534B (es) |
MX (2) | MX2020010365A (es) |
PE (1) | PE20190202A1 (es) |
RU (1) | RU2742885C2 (es) |
SG (1) | SG11201809672YA (es) |
TW (1) | TWI755393B (es) |
UY (1) | UY37222A (es) |
WO (1) | WO2017191104A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9988367B2 (en) * | 2016-05-03 | 2018-06-05 | Bayer Pharma Aktiengesellschaft | Amide-substituted pyridinyltriazole derivatives and uses thereof |
JP6911052B2 (ja) * | 2016-05-03 | 2021-07-28 | バイエル ファーマ アクチエンゲゼルシャフト | オキソアルキル置換フェニルトリアゾール誘導体およびその使用 |
UY37222A (es) * | 2016-05-03 | 2017-11-30 | Bayer Pharma AG | PROCEDIMIENTO PARA LA PREPARACIÓN DE DERIVADOS DE 1-FENILO-1,2,4-TRIAZOL SUSTITUIDOS POR 5-HIdroxIalQUILO |
WO2021259852A1 (en) | 2020-06-25 | 2021-12-30 | Bayer Aktiengesellschaft | Process for preparing 5-(alkoxycarbonyl)-and 5-(carboxamide)-1-aryl-1,2,4-triazole derivatives |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2007267860B2 (en) * | 2006-05-25 | 2012-08-09 | Synta Pharmaceuticals Corp. | Triazole compounds that modulate Hsp90 activity |
WO2010033626A1 (en) * | 2008-09-19 | 2010-03-25 | Institute For Oneworld Health | Compounds, compositions and methods comprising imidazole and triazole derivatives |
DE102010001064A1 (de) | 2009-03-18 | 2010-09-23 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 2-Acetamido-5-Aryl-1,2,4-triazolone und deren Verwendung |
PE20130683A1 (es) * | 2010-02-27 | 2013-06-20 | Bayer Ip Gmbh | Ariltriazolonas ligadas a bisarilo y su uso |
HUE034430T2 (en) * | 2012-05-08 | 2018-02-28 | Bayer Pharma AG | Process for the preparation of triazole compounds |
SG11201703199UA (en) * | 2014-11-03 | 2017-05-30 | Bayer Pharma AG | Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof |
US9988367B2 (en) * | 2016-05-03 | 2018-06-05 | Bayer Pharma Aktiengesellschaft | Amide-substituted pyridinyltriazole derivatives and uses thereof |
JP6911052B2 (ja) * | 2016-05-03 | 2021-07-28 | バイエル ファーマ アクチエンゲゼルシャフト | オキソアルキル置換フェニルトリアゾール誘導体およびその使用 |
UY37222A (es) * | 2016-05-03 | 2017-11-30 | Bayer Pharma AG | PROCEDIMIENTO PARA LA PREPARACIÓN DE DERIVADOS DE 1-FENILO-1,2,4-TRIAZOL SUSTITUIDOS POR 5-HIdroxIalQUILO |
-
2017
- 2017-05-02 UY UY0001037222A patent/UY37222A/es not_active Application Discontinuation
- 2017-05-02 PE PE2018002254A patent/PE20190202A1/es unknown
- 2017-05-02 CN CN201780027607.0A patent/CN109071500B/zh not_active Expired - Fee Related
- 2017-05-02 KR KR1020187031568A patent/KR20190003536A/ko not_active Application Discontinuation
- 2017-05-02 MX MX2020010365A patent/MX2020010365A/es unknown
- 2017-05-02 JP JP2018557408A patent/JP6921863B2/ja active Active
- 2017-05-02 WO PCT/EP2017/060367 patent/WO2017191104A1/de active Application Filing
- 2017-05-02 RU RU2018142264A patent/RU2742885C2/ru active
- 2017-05-02 US US16/098,238 patent/US10703742B2/en active Active
- 2017-05-02 CN CN202110424553.XA patent/CN113105403A/zh active Pending
- 2017-05-02 MX MX2018013336A patent/MX2018013336A/es unknown
- 2017-05-02 BR BR112018072528-5A patent/BR112018072528A2/pt active Search and Examination
- 2017-05-02 TW TW106114435A patent/TWI755393B/zh not_active IP Right Cessation
- 2017-05-02 SG SG11201809672YA patent/SG11201809672YA/en unknown
- 2017-05-02 CA CA3022789A patent/CA3022789A1/en active Pending
- 2017-05-02 EP EP17719636.7A patent/EP3452467A1/de not_active Withdrawn
- 2017-05-02 AU AU2017259872A patent/AU2017259872B2/en not_active Ceased
-
2018
- 2018-10-23 IL IL262534A patent/IL262534B/en active IP Right Grant
- 2018-10-31 CL CL2018003107A patent/CL2018003107A1/es unknown
- 2018-11-02 CO CONC2018/0011948A patent/CO2018011948A2/es unknown
-
2020
- 2020-05-21 US US16/880,933 patent/US20200299271A1/en not_active Abandoned
-
2021
- 2021-06-14 JP JP2021098486A patent/JP2021143193A/ja not_active Withdrawn
- 2021-09-22 AU AU2021236502A patent/AU2021236502A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
PE20190202A1 (es) | 2019-02-05 |
SG11201809672YA (en) | 2018-11-29 |
CO2018011948A2 (es) | 2018-11-22 |
US20200299271A1 (en) | 2020-09-24 |
BR112018072528A2 (pt) | 2019-03-26 |
EP3452467A1 (de) | 2019-03-13 |
US20190144431A1 (en) | 2019-05-16 |
WO2017191104A1 (de) | 2017-11-09 |
KR20190003536A (ko) | 2019-01-09 |
RU2018142264A3 (es) | 2020-08-19 |
TWI755393B (zh) | 2022-02-21 |
IL262534B (en) | 2021-04-29 |
AU2017259872A1 (en) | 2018-11-22 |
CN109071500A (zh) | 2018-12-21 |
JP2019514948A (ja) | 2019-06-06 |
US10703742B2 (en) | 2020-07-07 |
MX2018013336A (es) | 2019-05-09 |
AU2017259872B2 (en) | 2021-06-24 |
CA3022789A1 (en) | 2017-11-09 |
JP6921863B2 (ja) | 2021-08-18 |
RU2018142264A (ru) | 2020-06-03 |
RU2742885C2 (ru) | 2021-02-11 |
CL2018003107A1 (es) | 2019-02-22 |
TW201815782A (zh) | 2018-05-01 |
JP2021143193A (ja) | 2021-09-24 |
CN113105403A (zh) | 2021-07-13 |
MX2020010365A (es) | 2022-04-06 |
AU2021236502A1 (en) | 2021-10-21 |
CN109071500B (zh) | 2021-05-18 |
IL262534A (en) | 2018-12-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20230612 |