UY34361A - Métodos para preparar análogos nucleotídicos anti virales. - Google Patents
Métodos para preparar análogos nucleotídicos anti virales.Info
- Publication number
- UY34361A UY34361A UY34361A UY34361A UY34361A UY 34361 A UY34361 A UY 34361A UY 34361 A UY34361 A UY 34361A UY 34361 A UY34361 A UY 34361A UY 34361 A UY34361 A UY 34361A
- Authority
- UY
- Uruguay
- Prior art keywords
- methods
- nucleotytic
- analogs
- prepare anti
- anti viral
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161544950P | 2014-04-11 | 2014-04-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY34361A true UY34361A (es) | 2013-05-31 |
Family
ID=47297386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY34361A UY34361A (es) | 2014-04-11 | 2012-10-03 | Métodos para preparar análogos nucleotídicos anti virales. |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US8664386B2 (enExample) |
| EP (2) | EP3333173B1 (enExample) |
| JP (2) | JP6190372B2 (enExample) |
| KR (3) | KR102139440B1 (enExample) |
| CN (4) | CN107266498B (enExample) |
| AR (1) | AR088109A1 (enExample) |
| AU (3) | AU2012319172B2 (enExample) |
| BR (2) | BR112014011340A2 (enExample) |
| CA (2) | CA2850466C (enExample) |
| CL (1) | CL2014000827A1 (enExample) |
| CO (1) | CO6940431A2 (enExample) |
| CR (1) | CR20140204A (enExample) |
| EA (1) | EA027086B1 (enExample) |
| EC (1) | ECSP14000074A (enExample) |
| ES (2) | ES2661705T3 (enExample) |
| HK (1) | HK1255222B (enExample) |
| IL (1) | IL231879B (enExample) |
| MX (1) | MX353064B (enExample) |
| PE (1) | PE20141160A1 (enExample) |
| PL (1) | PL3333173T3 (enExample) |
| PT (2) | PT3333173T (enExample) |
| SI (1) | SI3333173T1 (enExample) |
| TW (4) | TWI557133B (enExample) |
| UY (1) | UY34361A (enExample) |
| WO (1) | WO2013052094A2 (enExample) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013025788A1 (en) | 2011-08-16 | 2013-02-21 | Gilead Sciences, Inc. | Tenofovir alafenamide hemifumarate |
| PT3333173T (pt) | 2014-04-11 | 2019-09-10 | Gilead Sciences Inc | Métodos de preparação de análogos de nucleótidos antivirais |
| CN107312039B (zh) | 2012-08-30 | 2019-06-25 | 江苏豪森药业集团有限公司 | 一种替诺福韦前药的制备方法 |
| ZA201404147B (en) * | 2013-06-07 | 2016-01-27 | Cipla Ltd | An efficient process for separation of diastereomers of 9-[(r)-2-[[(r,s)-[[(s)-1-(isopropoxycarbonyl)ethyl]amino]-phenoxyphosphinyl] methoxy]propyl]adenine |
| CN104628773B (zh) * | 2013-11-06 | 2018-10-23 | 杭州和泽医药科技有限公司 | (r)-9-[2-(磷酰苯酚基甲氧基)丙基]腺嘌呤的制备方法 |
| WO2015079455A2 (en) * | 2013-11-27 | 2015-06-04 | Laurus Labs Private Limited | A recycling process for preparing tenofovir alafenamide diastereomers |
| WO2015107451A2 (en) * | 2014-01-14 | 2015-07-23 | Mylan Laboratories Ltd. | Purification of tenofovir alafenamide and its intermediates |
| TWI660965B (zh) | 2014-01-15 | 2019-06-01 | 美商基利科學股份有限公司 | 泰諾福韋之固體形式 |
| CN105531281B (zh) * | 2014-04-21 | 2017-12-15 | 四川海思科制药有限公司 | 一种核苷类似物及其中间体的制备方法 |
| WO2015197006A1 (zh) * | 2014-06-25 | 2015-12-30 | 四川海思科制药有限公司 | 一种取代的氨基酸硫酯类化合物、其组合物及应用 |
| CN105399771B (zh) * | 2014-07-21 | 2020-11-24 | 江苏豪森药业集团有限公司 | 替诺福韦前药晶型及其制备方法和用途 |
| CN108148094A (zh) * | 2014-11-12 | 2018-06-12 | 四川海思科制药有限公司 | 一种替诺福韦艾拉酚胺富马酸盐晶型c及其制备方法和用途 |
| CN104817593B (zh) * | 2015-04-27 | 2016-11-16 | 广州同隽医药科技有限公司 | 半富马酸替诺福韦艾拉酚胺关键中间体的合成工艺 |
| PL3331891T3 (pl) | 2015-08-05 | 2022-03-28 | Eisai R&D Management Co., Ltd. | Sposób wytwarzania zasadniczo czystego diastereoizomerycznie oligomeru amidofosforanowego, oligomer amidofosforanowy wytworzony takim sposobem oraz kompozycja farmaceutyczna zawierająca taki oligomer amidofosforanowy |
| TWI616452B (zh) * | 2015-08-26 | 2018-03-01 | Preparation method of nucleoside analog and intermediate thereof | |
| CN105330700A (zh) * | 2015-12-17 | 2016-02-17 | 中国药科大学 | 富马酸替诺福韦艾拉酚胺杂质的制备方法 |
| WO2017118928A1 (en) | 2016-01-06 | 2017-07-13 | Lupin Limited | Process for the separation of diastereomers of tenofovir alafenamide |
| CZ2016156A3 (cs) * | 2016-03-17 | 2017-09-27 | Zentiva, K.S. | Způsob přípravy diastereomerně čistého Tenofoviru Alafenamidu nebo jeho solí |
| CN107286190A (zh) * | 2016-04-13 | 2017-10-24 | 刘沛 | 核苷之烃氧基苄基氨基磷酸/膦酸酯衍生物的制备及其医药用途 |
| CN109641874A (zh) | 2016-05-10 | 2019-04-16 | C4医药公司 | 用于靶蛋白降解的c3-碳连接的戊二酰亚胺降解决定子体 |
| EP3454856B1 (en) | 2016-05-10 | 2024-09-11 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
| WO2017197051A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Amine-linked c3-glutarimide degronimers for target protein degradation |
| ES2990061T3 (es) | 2016-05-10 | 2024-11-28 | C4 Therapeutics Inc | Degronímeros espirocíclicos para la degradación de proteínas diana |
| CN106565785B (zh) * | 2016-11-09 | 2019-11-12 | 周雨恬 | 一种具有抗hbv/hiv活性的核苷氨基磷酸酯类化合物及其盐和用途 |
| CN106946935B (zh) * | 2017-04-28 | 2020-01-07 | 福建广生堂药业股份有限公司 | 一种非对映异构体核苷衍生物的制备方法 |
| EP3641762A4 (en) | 2017-06-20 | 2021-03-10 | C4 Therapeutics, Inc. | N / O-LINKED DEGRONES AND DEGRONIMERS FOR PROTEIN DEGRADATION |
| EP3692041A1 (en) * | 2017-10-04 | 2020-08-12 | Celgene Corporation | Processes for the preparation of cis-4 [2-{(3s.4r)-3-fluorooxan-4-yl]amino)-8-(2,4,6-trichloroanilino)-9h-purin-9-yl]-1-methylcyclohexane-1-carboxamide |
| CN109942633B (zh) * | 2017-12-20 | 2021-08-31 | 上海新礼泰药业有限公司 | 替诺福韦艾拉酚胺中间体的制备方法 |
| CN109942632B (zh) * | 2017-12-20 | 2021-08-31 | 上海博志研新药物研究有限公司 | 替诺福韦艾拉酚胺中间体的制备方法 |
| CN110092803A (zh) * | 2018-01-31 | 2019-08-06 | 北京睿创康泰医药研究院有限公司 | 替诺福韦艾拉酚胺富马酸盐工艺杂质的制备及其应用 |
| CN108409788B (zh) * | 2018-03-12 | 2020-05-08 | 科兴生物制药股份有限公司 | 一种富马酸替诺福韦艾拉酚胺的制备方法 |
| CN110305163A (zh) * | 2018-03-27 | 2019-10-08 | 北京济美堂医药研究有限公司 | 替诺福韦艾拉酚胺半富马酸盐的制备方法 |
| CN108467410B (zh) * | 2018-04-09 | 2021-04-09 | 重庆三圣实业股份有限公司 | 一种taf中间体的制备方法及产品和应用 |
| CN108484672A (zh) * | 2018-05-23 | 2018-09-04 | 中国药科大学制药有限公司 | 磷丙替诺福韦的手性拆分方法 |
| CN108822149B (zh) * | 2018-06-01 | 2020-08-11 | 成都苑东生物制药股份有限公司 | 一种富马酸替诺福韦艾拉酚胺关键中间体的制备方法 |
| CN110283208B (zh) * | 2018-06-22 | 2022-07-08 | 南京济群医药科技股份有限公司 | 一种替诺福韦艾拉酚胺的手性拆分方法 |
| CN109081853A (zh) * | 2018-09-03 | 2018-12-25 | 南京正大天晴制药有限公司 | 一种磷丙替诺福韦有关物质的制备方法 |
| CN111484527A (zh) * | 2019-01-25 | 2020-08-04 | 上海清松制药有限公司 | 一种替诺福韦艾拉酚胺中间体的制备方法 |
| CN113874079B (zh) | 2019-03-22 | 2024-11-08 | 吉利德科学公司 | 桥连三环氨基甲酰基吡啶酮化合物及其药学用途 |
| CN111943981A (zh) * | 2019-05-14 | 2020-11-17 | 博瑞生物医药泰兴市有限公司 | 一种磷丙替诺福韦的制备方法 |
| CN114409706B (zh) * | 2019-07-01 | 2023-11-28 | 上海医药工业研究院 | 一种苯基氢膦酸酯及其中间体的制备方法 |
| WO2021011891A1 (en) | 2019-07-18 | 2021-01-21 | Gilead Sciences, Inc. | Long-acting formulations of tenofovir alafenamide |
| CN112390824B (zh) * | 2019-08-19 | 2022-07-05 | 鲁南制药集团股份有限公司 | 一种替诺福韦艾拉酚胺中间体的制备方法 |
| CN110981911A (zh) * | 2019-10-08 | 2020-04-10 | 浙江车头制药股份有限公司 | 一种替诺福韦艾拉酚胺的制备方法 |
| CN111171076A (zh) * | 2019-12-26 | 2020-05-19 | 合肥启旸生物科技有限公司 | 一种替诺福韦二聚体的制备方法 |
| JP2023518433A (ja) | 2020-03-20 | 2023-05-01 | ギリアード サイエンシーズ， インコーポレイテッド | ４’－ｃ－置換－２－ハロ－２’－デオキシアデノシンヌクレオシドのプロドラッグ並びにその製造法及び使用法 |
| KR20210125298A (ko) | 2020-04-08 | 2021-10-18 | 주식회사 파마코스텍 | 테노포비어 알라펜아미드 헤미타르트레이트의 신규한 제조방법 |
| CN116437958A (zh) | 2020-11-11 | 2023-07-14 | 吉利德科学公司 | 鉴定对采用gp120 CD4结合位点导向的抗体的疗法敏感的HIV患者的方法 |
| KR20220141457A (ko) | 2021-04-13 | 2022-10-20 | 경동제약 주식회사 | 신규 결정형의 테노포비어 알라펜아미드 말레산염 및 이를 포함하는 약제학적 조성물 |
| PT4445900T (pt) | 2021-12-03 | 2025-08-13 | Gilead Sciences Inc | Compostos terapêuticos para a infecção pelo vírus do hiv |
| TWI843506B (zh) | 2022-04-06 | 2024-05-21 | 美商基利科學股份有限公司 | 橋聯三環胺甲醯基吡啶酮化合物及其用途 |
| TWI867601B (zh) | 2022-07-01 | 2024-12-21 | 美商基利科學股份有限公司 | 可用於ｈｉｖ病毒感染之疾病預防性或治療性治療的治療性化合物 |
| CN119768183A (zh) | 2022-08-26 | 2025-04-04 | 吉利德科学公司 | 用于广泛中和抗体的给药和安排方案 |
| WO2024076915A1 (en) | 2022-10-04 | 2024-04-11 | Gilead Sciences, Inc. | 4'-thionucleoside analogues and their pharmaceutical use |
| TW202444363A (zh) | 2023-04-19 | 2024-11-16 | 美商基利科學股份有限公司 | 殼體抑制劑之給藥方案 |
| US20250011352A1 (en) | 2023-05-31 | 2025-01-09 | Gilead Sciences, Inc. | Solid forms |
| US20250042926A1 (en) | 2023-05-31 | 2025-02-06 | Gilead Sciences, Inc. | Therapeutic compounds for hiv |
| WO2025029247A1 (en) | 2023-07-28 | 2025-02-06 | Gilead Sciences, Inc. | Weekly regimen of lenacapavir for the treatment and prevention of hiv |
| WO2025042394A1 (en) | 2023-08-23 | 2025-02-27 | Gilead Sciences, Inc. | Dosing regimen of hiv capsid inhibitor |
| TW202530227A (zh) | 2023-10-11 | 2025-08-01 | 美商基利科學股份有限公司 | 橋聯三環胺甲醯基吡啶酮化合物及其用途 |
| US20250127801A1 (en) | 2023-10-11 | 2025-04-24 | Gilead Sciences, Inc. | Bridged tricyclic carbamoylpyridone compounds and uses thereof |
| US20250120989A1 (en) | 2023-10-11 | 2025-04-17 | Gilead Sciences, Inc. | Bridged tricyclic carbamoylpyridone compounds and uses thereof |
| WO2025137245A1 (en) | 2023-12-22 | 2025-06-26 | Gilead Sciences, Inc. | Solid forms of hiv integrase inhibitors |
| WO2025184609A1 (en) | 2024-03-01 | 2025-09-04 | Gilead Sciences, Inc. | Antiviral compounds |
| US20250289822A1 (en) | 2024-03-01 | 2025-09-18 | Gilead Sciences, Inc. | Solid forms of hiv integrase inhibitors |
| WO2025184447A1 (en) | 2024-03-01 | 2025-09-04 | Gilead Sciences, Inc. | Pharmaceutical compositions comprising hiv integrase inhibitors |
| WO2025260028A1 (en) | 2024-06-14 | 2025-12-18 | Gilead Sciences, Inc. | Pharmaceutical compositions comprising hiv integrase inhibitors |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001282941C1 (en) * | 2000-07-21 | 2016-12-22 | Gilead Sciences, Inc. | Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same |
| US20050239054A1 (en) | 2002-04-26 | 2005-10-27 | Arimilli Murty N | Method and compositions for identifying anti-HIV therapeutic compounds |
| EP1778251B1 (en) | 2004-07-27 | 2011-04-13 | Gilead Sciences, Inc. | Nucleoside phosphonate conjugates as anti hiv agents |
| CN102516259B (zh) | 2006-03-29 | 2014-12-10 | 吉里德科学公司 | 制备hiv蛋白酶抑制剂的方法 |
| AR061839A1 (es) * | 2006-07-07 | 2008-09-24 | Gilead Sciences Inc | Compuestos y composiciones farmaceuticas que activan selectivamente a receptores tipo toll 7(tlr7), y uso de los mismos como agentes antivirales |
| NZ573888A (en) * | 2006-07-21 | 2012-02-24 | Gilead Sciences Inc | Aza-peptide protease inhibitors |
| NZ573793A (en) * | 2006-07-24 | 2012-01-12 | Korea Res Inst Chem Tech | Hiv reverse transcriptase inhibitors |
| KR20100041798A (ko) * | 2007-06-29 | 2010-04-22 | 한국화학연구원 | 신규 ｈｉｖ 역전사효소 억제제 |
| WO2013025788A1 (en) | 2011-08-16 | 2013-02-21 | Gilead Sciences, Inc. | Tenofovir alafenamide hemifumarate |
| PT3333173T (pt) * | 2014-04-11 | 2019-09-10 | Gilead Sciences Inc | Métodos de preparação de análogos de nucleótidos antivirais |
-
2012
- 2012-10-03 PT PT18153951T patent/PT3333173T/pt unknown
- 2012-10-03 TW TW101136508A patent/TWI557133B/zh active
- 2012-10-03 AR ARP120103681 patent/AR088109A1/es not_active Application Discontinuation
- 2012-10-03 AU AU2012319172A patent/AU2012319172B2/en active Active
- 2012-10-03 SI SI201231626T patent/SI3333173T1/sl unknown
- 2012-10-03 UY UY34361A patent/UY34361A/es not_active Application Discontinuation
- 2012-10-03 CN CN201710365515.5A patent/CN107266498B/zh active Active
- 2012-10-03 ES ES12798029.0T patent/ES2661705T3/es active Active
- 2012-10-03 CA CA2850466A patent/CA2850466C/en active Active
- 2012-10-03 ES ES18153951T patent/ES2746859T3/es active Active
- 2012-10-03 EP EP18153951.1A patent/EP3333173B1/en active Active
- 2012-10-03 CN CN202311252160.0A patent/CN117343101A/zh active Pending
- 2012-10-03 BR BR112014011340A patent/BR112014011340A2/pt unknown
- 2012-10-03 PL PL18153951T patent/PL3333173T3/pl unknown
- 2012-10-03 MX MX2014003952A patent/MX353064B/es active IP Right Grant
- 2012-10-03 EP EP12798029.0A patent/EP2764002B1/en active Active
- 2012-10-03 PT PT127980290T patent/PT2764002T/pt unknown
- 2012-10-03 KR KR1020197019875A patent/KR102139440B1/ko active Active
- 2012-10-03 CN CN202110408116.9A patent/CN113264959A/zh active Pending
- 2012-10-03 PE PE2014000495A patent/PE20141160A1/es not_active Application Discontinuation
- 2012-10-03 CN CN201280048965.7A patent/CN103842366B/zh active Active
- 2012-10-03 KR KR1020207021316A patent/KR20200090975A/ko not_active Withdrawn
- 2012-10-03 TW TW108139308A patent/TWI709567B/zh active
- 2012-10-03 CA CA3042169A patent/CA3042169C/en active Active
- 2012-10-03 EA EA201490753A patent/EA027086B1/ru unknown
- 2012-10-03 TW TW106145797A patent/TWI689513B/zh active
- 2012-10-03 WO PCT/US2012/000441 patent/WO2013052094A2/en not_active Ceased
- 2012-10-03 KR KR1020147011619A patent/KR102033802B1/ko active Active
- 2012-10-03 TW TW105126598A patent/TWI613211B/zh active
- 2012-10-03 US US13/573,666 patent/US8664386B2/en active Active
- 2012-10-03 JP JP2014534535A patent/JP6190372B2/ja active Active
-
2014
- 2014-01-14 US US14/154,313 patent/US9029534B2/en active Active
- 2014-04-02 IL IL23187914A patent/IL231879B/en active IP Right Grant
- 2014-04-03 CL CL2014000827A patent/CL2014000827A1/es unknown
- 2014-04-11 BR BR102014008928-4A patent/BR102014008928B1/pt active IP Right Grant
- 2014-05-02 CO CO14093468A patent/CO6940431A2/es active IP Right Grant
- 2014-05-05 CR CR20140204A patent/CR20140204A/es unknown
- 2014-05-05 EC ECIEPI201474A patent/ECSP14000074A/es unknown
- 2014-08-21 AU AU2014215976A patent/AU2014215976B2/en active Active
-
2015
- 2015-02-06 HK HK18114351.4A patent/HK1255222B/en unknown
- 2015-04-08 US US14/681,955 patent/US9346841B2/en active Active
-
2016
- 2016-04-21 US US15/135,357 patent/US9676804B2/en active Active
- 2016-09-19 AU AU2016228317A patent/AU2016228317B2/en active Active
-
2017
- 2017-04-19 JP JP2017083047A patent/JP2017160228A/ja not_active Withdrawn
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UY34361A (es) | Métodos para preparar análogos nucleotídicos anti virales. | |
| ECSP18048718A (es) | Imidazolilimidazoles condensados como compuestos antivirales | |
| AR090455A1 (es) | Metodos para preparar analogos de nucleotidos sustituidos | |
| CO6680607A2 (es) | Métodos para la preparación de profármacos de fosforamidato diastereoméricamente puros | |
| MD20180040A2 (ro) | Inhibitori ai virusului hepatic C | |
| PH12015501934B1 (en) | New octahydro - pyrrolo [3,4-c] - pyrrole derivatives and analogs thereof as autotaxin inhibitors | |
| IN2014MU00118A (enExample) | ||
| CR20130531A (es) | Derivados de nucleósidos 2'-sustituidos y métodos de uso de los mismos para el tratamiento de enfermedades virales | |
| MX2014013660A (es) | Compuestos antivirales inhibidores del virus de hepatitis c (vhc) ns5b. | |
| GT201300021A (es) | Proceso para preparar compuestos antivirales | |
| IN2013MU01967A (enExample) | ||
| UY34245A (es) | Compuestos antivirales para el tratamiento de la hepatitis c (hcv), y métodos de tratamiento. | |
| PH12014501353B1 (en) | Method for preparing cysteine or a derivative thereof using a novel o-phosphoserine sulfhydrylase | |
| CR20140078A (es) | Compuestos de benzofurano para el tratamiento de infecciones por el virus de hepatitis c (hcv) | |
| MX2013014969A (es) | Metodo para preparar zeolitas tipo lta utilizando un agente director de estructura novedoso. | |
| PH12014501327A1 (en) | Processes for making magnolol analogs | |
| MX364851B (es) | Amina adecuada como catalizador de material de poliuretano (pu). | |
| CR20110423A (es) | Macrolindo anti-inflamatorio | |
| MY163245A (en) | Hepatitis c virus inhibitors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20201020 |