UY24386A1 - Nuevos taxoides, su preparación y composiciones farmacéuticas que los contienen. - Google Patents

Nuevos taxoides, su preparación y composiciones farmacéuticas que los contienen.

Info

Publication number
UY24386A1
UY24386A1 UY24386A UY24386A UY24386A1 UY 24386 A1 UY24386 A1 UY 24386A1 UY 24386 A UY24386 A UY 24386A UY 24386 A UY24386 A UY 24386A UY 24386 A1 UY24386 A1 UY 24386A1
Authority
UY
Uruguay
Prior art keywords
contain
preparation
pharmaceutical compositions
new taxoids
taxoids
Prior art date
Application number
UY24386A
Other languages
English (en)
Spanish (es)
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of UY24386A1 publication Critical patent/UY24386A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
UY24386A 1995-12-22 2000-12-02 Nuevos taxoides, su preparación y composiciones farmacéuticas que los contienen. UY24386A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9515379A FR2742751B1 (fr) 1995-12-22 1995-12-22 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
UY24386A1 true UY24386A1 (es) 2001-08-27

Family

ID=9485871

Family Applications (1)

Application Number Title Priority Date Filing Date
UY24386A UY24386A1 (es) 1995-12-22 2000-12-02 Nuevos taxoides, su preparación y composiciones farmacéuticas que los contienen.

Country Status (40)

Country Link
US (1) US5728849A (enExample)
EP (1) EP0876362B1 (enExample)
JP (1) JP3953106B2 (enExample)
KR (1) KR100500351B1 (enExample)
CN (1) CN1103766C (enExample)
AR (1) AR005197A1 (enExample)
AT (1) ATE250593T1 (enExample)
AU (1) AU712597B2 (enExample)
BG (1) BG63204B1 (enExample)
BR (1) BR9612135A (enExample)
CA (1) CA2238884C (enExample)
CO (1) CO4520184A1 (enExample)
CZ (1) CZ294972B6 (enExample)
DE (1) DE69630145T2 (enExample)
DK (1) DK0876362T3 (enExample)
DZ (1) DZ2149A1 (enExample)
EA (1) EA001533B1 (enExample)
ES (1) ES2202490T3 (enExample)
FR (1) FR2742751B1 (enExample)
HU (1) HU225032B1 (enExample)
IL (1) IL124994A (enExample)
IN (4) IN186768B (enExample)
MA (1) MA26412A1 (enExample)
MX (1) MX9804688A (enExample)
MY (1) MY113934A (enExample)
NO (1) NO317358B1 (enExample)
NZ (1) NZ324337A (enExample)
OA (1) OA10700A (enExample)
PE (1) PE25198A1 (enExample)
PL (1) PL189311B1 (enExample)
PT (1) PT876362E (enExample)
RO (1) RO116194B1 (enExample)
SK (1) SK282835B6 (enExample)
TN (1) TNSN96169A1 (enExample)
TR (1) TR199801179T2 (enExample)
TW (1) TW371659B (enExample)
UA (1) UA48205C2 (enExample)
UY (1) UY24386A1 (enExample)
WO (1) WO1997023473A1 (enExample)
ZA (1) ZA9610737B (enExample)

Families Citing this family (41)

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GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
HUP0200759A3 (en) 2000-02-02 2002-10-28 Univ Florida State Res Found C10 carbonate substituted taxanes as antitumor agents and pharmaceutical compositions containing them and their use
SK286975B6 (sk) * 2001-02-24 2009-08-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Xantínové deriváty, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
AU2003239511A1 (en) * 2003-05-20 2004-12-13 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
EP1669358A1 (en) * 2004-12-07 2006-06-14 Aventis Pharma S.A. Cytotoxic agents comprising new taxanes
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
BRPI0711558A2 (pt) 2006-05-04 2011-11-08 Boeringer Ingelheim Internat Gmbh polimorfos
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
US20080207743A1 (en) * 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
CA2696579C (en) * 2007-08-17 2017-01-24 Boehringer Ingelheim International Gmbh Purine derivatives for use in the treatment of fab-related diseases
PE20091730A1 (es) 2008-04-03 2009-12-10 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
KR20190016601A (ko) 2008-08-06 2019-02-18 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
NZ604091A (en) * 2008-08-15 2014-08-29 Boehringer Ingelheim Int Purin derivatives for use in the treatment of fab-related diseases
BRPI0919288A2 (pt) 2008-09-10 2015-12-15 Boehring Ingelheim Internat Gmbh teriapia de combinação para tratamento de diabetes e condições relacionadas.
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
AU2009331471B2 (en) 2008-12-23 2015-09-03 Boehringer Ingelheim International Gmbh Salt forms of organic compound
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
PH12012501037A1 (en) 2009-11-27 2013-01-14 Boehringer Ingelheim Int Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
CA2797310C (en) 2010-05-05 2020-03-31 Boehringer Ingelheim International Gmbh Glp-1 receptor agonist and dpp-4 inhibitor combination therapy
KR20230051307A (ko) 2010-06-24 2023-04-17 베링거 인겔하임 인터내셔날 게엠베하 당뇨병 요법
US9034883B2 (en) 2010-11-15 2015-05-19 Boehringer Ingelheim International Gmbh Vasoprotective and cardioprotective antidiabetic therapy
ES2713566T3 (es) 2011-07-15 2019-05-22 Boehringer Ingelheim Int Derivado de quinazolina dimérico sustituido, su preparación y su uso en composiciones farmacéuticas para el tratamiento de la diabetes de tipo I y II
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
EP4151218A1 (en) 2012-05-14 2023-03-22 Boehringer Ingelheim International GmbH Linagliptin, a xanthine derivative as dpp-4 inhibitor, for use in the treatment of sirs and/or sepsis
US20130303462A1 (en) 2012-05-14 2013-11-14 Boehringer Ingelheim International Gmbh Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
EP2922818B1 (en) 2012-11-24 2018-09-05 Hangzhou Dac Biotech Co., Ltd Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
FR3010839B1 (fr) * 2013-09-17 2017-04-21 Schneider Electric Ind Sas Dispositif de raccordement electrique d'au moins un conducteur dans une borne appartenant a un appareil electrique
EP3110449B1 (en) 2014-02-28 2023-06-28 Boehringer Ingelheim International GmbH Medical use of a dpp-4 inhibitor
AU2014384434B2 (en) 2014-02-28 2016-11-03 Hangzhou Dac Biotech Co., Ltd Charged linkers and their uses for conjugation
NZ739830A (en) 2015-07-12 2021-12-24 Hangzhou Dac Biotech Co Ltd Bridge linkers for conjugation of cell-binding molecules
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
WO2017211979A1 (en) 2016-06-10 2017-12-14 Boehringer Ingelheim International Gmbh Combinations of linagliptin and metformin
KR102345175B1 (ko) 2016-11-14 2021-12-31 항저우 디에이씨 바이오테크 씨오, 엘티디 결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
CA3236930A1 (en) 2021-11-03 2022-04-21 Hangzhou Dac Biotech Co., Ltd. Specific conjugation of an antibody

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017724C1 (ru) * 1990-07-12 1994-08-15 Дзе Юниверсити оф Канзас Способ получения производных таксола
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
RU2059631C1 (ru) * 1991-11-29 1996-05-10 Дзе Юниверсити оф Канзас Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью
US5352806A (en) * 1992-04-17 1994-10-04 Abbott Laboratories Taxol derivatives
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
IL107950A (en) * 1992-12-15 2001-04-30 Upjohn Co 7β, 8β - METHANO-TAXOLS, THEIR PREPARATION AND ANTINEOPLASTIC PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
HUP9904046A1 (hu) 2001-04-28
ATE250593T1 (de) 2003-10-15
HU225032B1 (en) 2006-05-29
IN188470B (enExample) 2002-09-28
TNSN96169A1 (fr) 2005-03-15
CZ294972B6 (cs) 2005-04-13
WO1997023473A1 (fr) 1997-07-03
ES2202490T3 (es) 2004-04-01
CN1103766C (zh) 2003-03-26
NO982580L (no) 1998-06-05
ZA9610737B (en) 1997-06-27
BR9612135A (pt) 1999-07-13
BG102569A (en) 1999-04-30
HUP9904046A3 (en) 2001-08-28
RO116194B1 (ro) 2000-11-30
IN188680B (enExample) 2002-10-26
IN188469B (enExample) 2002-09-28
CZ196198A3 (cs) 1998-09-16
TR199801179T2 (xx) 1998-10-21
FR2742751A1 (fr) 1997-06-27
MA26412A1 (fr) 2004-12-20
CO4520184A1 (es) 1997-10-15
IL124994A0 (en) 1999-01-26
PL327405A1 (en) 1998-12-07
JP3953106B2 (ja) 2007-08-08
OA10700A (fr) 2002-11-27
IN186768B (enExample) 2001-11-03
DZ2149A1 (fr) 2002-10-23
JP2000502671A (ja) 2000-03-07
EA199800588A1 (ru) 1998-12-24
IL124994A (en) 2000-12-06
CN1205697A (zh) 1999-01-20
CA2238884A1 (fr) 1997-07-03
AU712597B2 (en) 1999-11-11
NZ324337A (en) 2000-03-27
HK1017895A1 (en) 1999-12-03
UA48205C2 (uk) 2002-08-15
PT876362E (pt) 2004-02-27
AU1180997A (en) 1997-07-17
PE25198A1 (es) 1998-05-10
FR2742751B1 (fr) 1998-01-30
SK282835B6 (sk) 2002-12-03
DE69630145T2 (de) 2004-07-15
NO982580D0 (no) 1998-06-05
EA001533B1 (ru) 2001-04-23
KR19990076680A (ko) 1999-10-15
DK0876362T3 (da) 2004-02-02
TW371659B (en) 1999-10-11
KR100500351B1 (ko) 2005-12-21
MX9804688A (es) 1998-10-31
EP0876362B1 (fr) 2003-09-24
NO317358B1 (no) 2004-10-18
DE69630145D1 (de) 2003-10-30
US5728849A (en) 1998-03-17
CA2238884C (fr) 2007-02-06
PL189311B1 (pl) 2005-07-29
AR005197A1 (es) 1999-04-14
BG63204B1 (bg) 2001-06-29
EP0876362A1 (fr) 1998-11-11
SK85398A3 (en) 1998-11-04
MY113934A (en) 2002-06-29

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Legal Events

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ABAN Application deemed to be withdrawn (no publication fee paid)

Effective date: 20090526