US20110287955A1 - Polypeptide marker for diagnosis of arteriosclerosis, method for detection of arteriosclerosis by using the maker or the like, and kit for diagnosis of arteriosclerosis - Google Patents

Polypeptide marker for diagnosis of arteriosclerosis, method for detection of arteriosclerosis by using the maker or the like, and kit for diagnosis of arteriosclerosis Download PDF

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Publication number
US20110287955A1
US20110287955A1 US13/058,456 US200913058456A US2011287955A1 US 20110287955 A1 US20110287955 A1 US 20110287955A1 US 200913058456 A US200913058456 A US 200913058456A US 2011287955 A1 US2011287955 A1 US 2011287955A1
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Prior art keywords
arteriosclerosis
gene
marker
detecting
polypeptide
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Abandoned
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US13/058,456
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English (en)
Inventor
Rika Nakamura
Hideyuki Kuroda
Go Tomiyoshi
Takaki Hiwasa
Masaki Takiguchi
Naokatsu Saeki
Toshio Machida
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Fujikura Kasei Co Ltd
Chiba University NUC
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Fujikura Kasei Co Ltd
Chiba University NUC
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Assigned to NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY, FUJIKURA KASEI CO., LTD. reassignment NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: HIWASA, TAKAKI, KURODA, HIDEYUKI, MACHIDA, TOSHIO, NAKAMURA, RIKA, SAEKI, NAOKATSU, TAKIGUCHI, MASAKI, TOMIYOSHI, GO
Publication of US20110287955A1 publication Critical patent/US20110287955A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/323—Arteriosclerosis, Stenosis

Definitions

  • partial nucleotide sequence refers to a sequence being a part of the nucleotide sequence set forth in any one of SEQ ID NOs of the Sequence Listing mentioned above, consisting of twelve or more, preferably fifteen or more, more preferably eighteen or more, and yet more preferably twenty or more nucleotides (hereunder, the same definition will be applied).
  • the antigen protein was purified with the glutathione-Sepharose (Amersham Pharmacia).

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
US13/058,456 2008-08-15 2009-08-14 Polypeptide marker for diagnosis of arteriosclerosis, method for detection of arteriosclerosis by using the maker or the like, and kit for diagnosis of arteriosclerosis Abandoned US20110287955A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008209210 2008-08-15
JP2008-209210 2008-08-15
PCT/JP2009/064363 WO2010018870A1 (ja) 2008-08-15 2009-08-14 動脈硬化診断用ポリペプチドマーカー、及び該マーカー等を用いる動脈硬化の検出方法、並びに動脈硬化診断用キット

Related Parent Applications (1)

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PCT/JP2009/064363 A-371-Of-International WO2010018870A1 (ja) 2008-08-15 2009-08-14 動脈硬化診断用ポリペプチドマーカー、及び該マーカー等を用いる動脈硬化の検出方法、並びに動脈硬化診断用キット

Related Child Applications (1)

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US13/783,892 Division US9366681B2 (en) 2008-08-15 2013-03-04 Polypeptide marker for diagnosis of arteriosclerosis, method for detection of arteriosclerosis by using the maker or the like, and kit for diagnosis of arteriosclerosis

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US20110287955A1 true US20110287955A1 (en) 2011-11-24

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US13/058,456 Abandoned US20110287955A1 (en) 2008-08-15 2009-08-14 Polypeptide marker for diagnosis of arteriosclerosis, method for detection of arteriosclerosis by using the maker or the like, and kit for diagnosis of arteriosclerosis
US13/783,892 Active US9366681B2 (en) 2008-08-15 2013-03-04 Polypeptide marker for diagnosis of arteriosclerosis, method for detection of arteriosclerosis by using the maker or the like, and kit for diagnosis of arteriosclerosis

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Country Status (6)

Country Link
US (2) US20110287955A1 (ja)
EP (2) EP2319924B1 (ja)
JP (1) JP5742002B2 (ja)
KR (1) KR101506314B1 (ja)
CN (1) CN102099470B (ja)
WO (1) WO2010018870A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170093141A (ko) * 2014-11-07 2017-08-14 후지쿠라 가세이 가부시키가이샤 데옥시하이푸신·신타제 유전자를 지표로서 사용하는 동맥 경화 및 암의 검출 방법
CN114594273A (zh) * 2022-05-09 2022-06-07 上海众启生物科技有限公司 一种脑梗塞生物标记物及其应用

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KR101735891B1 (ko) * 2013-09-04 2017-05-16 이화여자대학교 산학협력단 신규한 심혈관계 질환의 진단 및 치료용 펩티드
KR101895767B1 (ko) * 2016-06-16 2018-09-07 충남대학교 산학협력단 동맥경화증 진단용 바이오 마커 조성물
CN106822869B (zh) * 2017-03-16 2020-10-30 北京热休生物技术有限公司 DEF8蛋白的多肽与热休克蛋白gp96的复合物在制备治疗与预防癌症药物中的应用
WO2019017897A1 (en) 2017-07-18 2019-01-24 Hewlett-Packard Development Company, L.P. RADIO MODULE CONFIGURATIONS FOR ANTENNAS
CN111521821A (zh) * 2020-05-09 2020-08-11 四川省人民医院 血管钙化的生物标志物及其应用
KR102418017B1 (ko) 2020-12-03 2022-07-05 충남대학교산학협력단 고지혈 환자의 죽상경화증 진단을 위한 정보 제공방법
CN116855472A (zh) * 2022-10-21 2023-10-10 唐山市人民医院 BAZ1B_K426hy的多克隆抗体及其免疫原多肽
CN117384271B (zh) * 2023-10-17 2024-08-16 青岛赛诺基因科技有限公司 与含赖氨酸甲基化修饰肽具有高亲和力的变体Chromo结构域

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170093141A (ko) * 2014-11-07 2017-08-14 후지쿠라 가세이 가부시키가이샤 데옥시하이푸신·신타제 유전자를 지표로서 사용하는 동맥 경화 및 암의 검출 방법
US20170343547A1 (en) * 2014-11-07 2017-11-30 Fujikura Kasei Co., Ltd. Arteriosclerosis and cancer detection method using deoxyhypusine synthase gene as indicator
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US11782061B2 (en) * 2014-11-07 2023-10-10 Fujikura Kasei Co., Ltd. Arteriosclerosis and cancer detection method using deoxyhypusine synthase gene as indicator
CN114594273A (zh) * 2022-05-09 2022-06-07 上海众启生物科技有限公司 一种脑梗塞生物标记物及其应用

Also Published As

Publication number Publication date
WO2010018870A1 (ja) 2010-02-18
KR101506314B1 (ko) 2015-04-06
EP3021121A1 (en) 2016-05-18
EP3021121B1 (en) 2018-06-06
CN102099470B (zh) 2014-11-12
JPWO2010018870A1 (ja) 2012-01-26
US20130183691A1 (en) 2013-07-18
US9366681B2 (en) 2016-06-14
KR20110027793A (ko) 2011-03-16
EP2319924A1 (en) 2011-05-11
EP2319924A4 (en) 2012-01-25
JP5742002B2 (ja) 2015-07-01
CN102099470A (zh) 2011-06-15
EP2319924B1 (en) 2016-03-09

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