UA96445C2 - 2-(замещенные амино)бензотиазолсульфонамидные ингибиторы вич-протеазы - Google Patents
2-(замещенные амино)бензотиазолсульфонамидные ингибиторы вич-протеазыInfo
- Publication number
- UA96445C2 UA96445C2 UAA200813950A UAA200813950A UA96445C2 UA 96445 C2 UA96445 C2 UA 96445C2 UA A200813950 A UAA200813950 A UA A200813950A UA A200813950 A UAA200813950 A UA A200813950A UA 96445 C2 UA96445 C2 UA 96445C2
- Authority
- UA
- Ukraine
- Prior art keywords
- protease inhibitors
- amino
- substituted
- benzothiazole sulfonamide
- hiv protease
- Prior art date
Links
- -1 2-(substituted-amino)-benzothiazole sulfonamide Chemical class 0.000 title abstract 3
- 239000004030 hiv protease inhibitor Substances 0.000 title abstract 2
- 238000009007 Diagnostic Kit Methods 0.000 abstract 1
- 229940124522 antiretrovirals Drugs 0.000 abstract 1
- 239000003903 antiretrovirus agent Substances 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06116003 | 2006-06-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA96445C2 true UA96445C2 (ru) | 2011-11-10 |
Family
ID=37596252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200813950A UA96445C2 (ru) | 2006-06-23 | 2007-06-22 | 2-(замещенные амино)бензотиазолсульфонамидные ингибиторы вич-протеазы |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US8202887B2 (OSRAM) |
| EP (1) | EP2035432B1 (OSRAM) |
| JP (1) | JP5232776B2 (OSRAM) |
| KR (1) | KR101419320B1 (OSRAM) |
| CN (1) | CN101479275B (OSRAM) |
| AP (1) | AP2069A (OSRAM) |
| AR (1) | AR061619A1 (OSRAM) |
| AT (1) | ATE544769T1 (OSRAM) |
| AU (1) | AU2007262943B2 (OSRAM) |
| BR (1) | BRPI0713487B1 (OSRAM) |
| CA (1) | CA2653233C (OSRAM) |
| CL (1) | CL2007001826A1 (OSRAM) |
| CY (1) | CY1112971T1 (OSRAM) |
| DK (1) | DK2035432T3 (OSRAM) |
| EA (1) | EA016387B1 (OSRAM) |
| ES (1) | ES2381129T3 (OSRAM) |
| IL (1) | IL195381A (OSRAM) |
| JO (1) | JO2841B1 (OSRAM) |
| MX (1) | MX2009000160A (OSRAM) |
| MY (1) | MY146805A (OSRAM) |
| NZ (1) | NZ573286A (OSRAM) |
| PE (1) | PE20080342A1 (OSRAM) |
| PL (1) | PL2035432T3 (OSRAM) |
| PT (1) | PT2035432E (OSRAM) |
| SI (1) | SI2035432T1 (OSRAM) |
| TW (1) | TWI415851B (OSRAM) |
| UA (1) | UA96445C2 (OSRAM) |
| UY (1) | UY30416A1 (OSRAM) |
| WO (1) | WO2007147884A1 (OSRAM) |
| ZA (1) | ZA200810350B (OSRAM) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3090B1 (ar) | 2009-12-11 | 2017-03-15 | Janssen Sciences Ireland Uc | 5- امينو-4- هيدروكسي-بنتويل اميدات |
| CA2802492C (en) | 2010-07-02 | 2018-10-16 | Gilead Sciences, Inc. | 2-quinolinyl-acetic acid derivatives as hiv antiviral compounds |
| ES2634490T3 (es) | 2010-07-02 | 2017-09-28 | Gilead Sciences, Inc. | Derivados de ácido napht-2-ylacetico para tratar el sida |
| US9024038B2 (en) | 2010-12-27 | 2015-05-05 | Purdue Research Foundation | Compunds and methods for treating HIV |
| AP2013007249A0 (en) | 2011-04-21 | 2013-11-30 | Gilead Sciences Inc | Benzothiazole compounds and their pharmaceutical use |
| WO2013103724A1 (en) | 2012-01-04 | 2013-07-11 | Gilead Sciences, Inc. | 2- (tert - butoxy) -2- (7 -methylquinolin- 6 - yl) acetic acid derivatives for treating aids |
| WO2013103738A1 (en) | 2012-01-04 | 2013-07-11 | Gilead Sciences, Inc. | Napthalene acetic acid derivatives against hiv infection |
| PH12014500842A1 (en) | 2012-04-20 | 2014-06-09 | Gilead Sciences Inc | Benzothiazol-6-yl acetic acid derivatives and their use for treating an hiv infection |
| WO2021209563A1 (en) | 2020-04-16 | 2021-10-21 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus |
| US12083099B2 (en) | 2020-10-28 | 2024-09-10 | Accencio LLC | Methods of treating symptoms of coronavirus infection with viral protease inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ527391A (en) * | 2001-02-14 | 2005-04-29 | Tibotec Pharm Ltd | Broadspectrum 2-(substituted-amino)-benzothiazole sulfonamide HIV protease inhibitors |
| AR037797A1 (es) * | 2001-12-12 | 2004-12-01 | Tibotec Pharm Ltd | Combinacion de inhibidores de proteasa dependientes del citocromo p450 |
| NZ538488A (en) * | 2002-08-02 | 2007-10-26 | Tibotec Pharm Ltd | Broadspectrum 2-amino-benzothiazole sulfonamide HIV protease inhibitors |
| US20080234288A1 (en) * | 2003-09-30 | 2008-09-25 | Kenneth Alan Simmen | Hcv Inhibiting Sulfonamides |
-
2007
- 2007-06-04 JO JO2007212A patent/JO2841B1/en active
- 2007-06-15 UY UY30416A patent/UY30416A1/es not_active Application Discontinuation
- 2007-06-21 CL CL2007001826A patent/CL2007001826A1/es unknown
- 2007-06-22 US US12/304,990 patent/US8202887B2/en not_active Expired - Fee Related
- 2007-06-22 NZ NZ573286A patent/NZ573286A/en not_active IP Right Cessation
- 2007-06-22 EA EA200970052A patent/EA016387B1/ru not_active IP Right Cessation
- 2007-06-22 PE PE2007000802A patent/PE20080342A1/es active IP Right Grant
- 2007-06-22 BR BRPI0713487-8A patent/BRPI0713487B1/pt not_active IP Right Cessation
- 2007-06-22 ES ES07765554T patent/ES2381129T3/es active Active
- 2007-06-22 AR ARP070102776A patent/AR061619A1/es active IP Right Grant
- 2007-06-22 AP AP2008004679A patent/AP2069A/en active
- 2007-06-22 KR KR1020097000754A patent/KR101419320B1/ko not_active Expired - Fee Related
- 2007-06-22 SI SI200730904T patent/SI2035432T1/sl unknown
- 2007-06-22 JP JP2009515891A patent/JP5232776B2/ja not_active Expired - Fee Related
- 2007-06-22 CA CA2653233A patent/CA2653233C/en active Active
- 2007-06-22 EP EP07765554A patent/EP2035432B1/en active Active
- 2007-06-22 PT PT07765554T patent/PT2035432E/pt unknown
- 2007-06-22 DK DK07765554.6T patent/DK2035432T3/da active
- 2007-06-22 UA UAA200813950A patent/UA96445C2/ru unknown
- 2007-06-22 AT AT07765554T patent/ATE544769T1/de active
- 2007-06-22 CN CN2007800236807A patent/CN101479275B/zh active Active
- 2007-06-22 PL PL07765554T patent/PL2035432T3/pl unknown
- 2007-06-22 AU AU2007262943A patent/AU2007262943B2/en not_active Ceased
- 2007-06-22 WO PCT/EP2007/056235 patent/WO2007147884A1/en not_active Ceased
- 2007-06-22 MX MX2009000160A patent/MX2009000160A/es active IP Right Grant
- 2007-06-22 MY MYPI20085209A patent/MY146805A/en unknown
- 2007-06-22 TW TW096122406A patent/TWI415851B/zh not_active IP Right Cessation
-
2008
- 2008-11-19 IL IL195381A patent/IL195381A/en active IP Right Grant
- 2008-12-05 ZA ZA200810350A patent/ZA200810350B/xx unknown
-
2012
- 2012-05-08 CY CY20121100429T patent/CY1112971T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA96445C2 (ru) | 2-(замещенные амино)бензотиазолсульфонамидные ингибиторы вич-протеазы | |
| WO2009137391A3 (en) | Benzene sulfonamide thiazole and oxazole compounds | |
| NO20090628L (no) | Pyridizinon derivativater | |
| BRPI0418639B8 (pt) | compostos inibidores de dipeptidil peptidase, assim como composição farmacêutica contendo os mesmos | |
| CR11618A (es) | Inhibidores macrocíclicos de serina proteasa | |
| EA200870217A1 (ru) | 4-арил-2-аминопиримидины или 4-арил-2-аминоалкилпиримидины в качестве модуляторов jak-2 и содержащие их фармацевтические композиции | |
| CL2007002887A1 (es) | Compuestos derivados de heterociclos, inhibidores de metaloproteinasa de la matriz (mmp); compuesto intermediario; composicion farmaceutica; kit farmaceutico; y uso en la prevencion y tratamiento en afecciones mediadas por metaloproteinasas de la mat | |
| NO20090910L (no) | Sulfonamid-derivater som adrenerge agonister og muskariniske antagonister | |
| TNSN07405A1 (en) | Herbicidal compositions | |
| CL2007003540A1 (es) | Compuestos derivados de macrociclos, inhibidores de la proteasa serina de hepatitis c; procedimiento de preparacion; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la hepatitis c. | |
| FR2924118B1 (fr) | Fragments d'anticorps inhibiteurs de la proteine nef du vih. | |
| MX2009004290A (es) | Inhibidores de proteasas de catepsina. | |
| UA96277C2 (en) | Benzimidazole derivatives | |
| TW200801015A (en) | Substituted aminophenylsulfonamide compounds as HIV protease inhibitor | |
| MXPA04011466A (es) | Inhibidores de la proteasa de hiv de benzisoxazol sulfonamida sustituida de amplio espectro. | |
| SG151306A1 (en) | Novel benzothiazoles and the use thereof as medicaments | |
| BRPI0414199A (pt) | inibidores de entrada do vìrus hiv | |
| CL2008002058A1 (es) | Metodo para la preparacion de trifluoralquil-fenil-sulfonamidas y de sulfonamidas heterociclicas usando n-trifluoroacteilmorfolina; su metodo de preparacion y su uso. | |
| WO2006091861A3 (en) | Compositions and methods relating to cns lymphoma | |
| DE602007005387D1 (de) | Ptors | |
| WO2008003752A8 (en) | 2 -amino benzimidazole derivatives and their use as modulators of small - conductance calcium -act ivated potassium channels | |
| TW200710091A (en) | (1,10B-dihydro-2-(aminoalkyl-phenyl)-5H-pyrazolo [1,5-c][1,3]benzoxazin-5-yl)phenyl methanone derivatives as HIV viral replication inhibitors | |
| DK1912954T3 (da) | Hidtil ukendte cysteinproteaseinhibitorer og deres terapeutiske applikationer | |
| WO2007066200A3 (en) | Inhibitors of cysteine proteases, the pharmaceutical compositions thereof and their therapeutic applications | |
| TW200738731A (en) | Substituted aminophenylsulfonamide compounds and derivatives as HIV protease inhibitor |