ATE490958T1 - Als agonisten für den nikotinischen acetylcholinrezeptor geeignete azabicycloalkanderivate - Google Patents
Als agonisten für den nikotinischen acetylcholinrezeptor geeignete azabicycloalkanderivateInfo
- Publication number
- ATE490958T1 ATE490958T1 AT06721069T AT06721069T ATE490958T1 AT E490958 T1 ATE490958 T1 AT E490958T1 AT 06721069 T AT06721069 T AT 06721069T AT 06721069 T AT06721069 T AT 06721069T AT E490958 T1 ATE490958 T1 AT E490958T1
- Authority
- AT
- Austria
- Prior art keywords
- azabicycloal
- cander
- agonists
- acetylcholine receptor
- nicotinic acetylcholine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65844405P | 2005-03-04 | 2005-03-04 | |
| PCT/US2006/006756 WO2006096358A1 (en) | 2005-03-04 | 2006-02-27 | Azabicycloalkane derivatives useful as nicotinic acetylcholine receptor agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE490958T1 true ATE490958T1 (de) | 2010-12-15 |
Family
ID=36499615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06721069T ATE490958T1 (de) | 2005-03-04 | 2006-02-27 | Als agonisten für den nikotinischen acetylcholinrezeptor geeignete azabicycloalkanderivate |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20080261999A1 (de) |
| EP (1) | EP1858857B1 (de) |
| AT (1) | ATE490958T1 (de) |
| DE (1) | DE602006018713D1 (de) |
| ES (1) | ES2354905T3 (de) |
| WO (1) | WO2006096358A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8580842B2 (en) | 2003-09-30 | 2013-11-12 | Abbott Gmbh & Co. Kg | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them |
| FR2870846B1 (fr) | 2004-05-25 | 2006-08-04 | Sanofi Synthelabo | Derives de tetrahydroisoquinolylsulfonamides, leur preparation et leur utilisation en therapeutique |
| US8486979B2 (en) | 2006-12-12 | 2013-07-16 | Abbvie Inc. | 1,2,4 oxadiazole compounds and methods of use thereof |
| US20080167286A1 (en) | 2006-12-12 | 2008-07-10 | Abbott Laboratories | Pharmaceutical compositions and their methods of use |
| UY30846A1 (es) | 2006-12-30 | 2008-07-31 | Abbott Gmbh & Amp | Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos |
| TW200845977A (en) * | 2007-03-30 | 2008-12-01 | Targacept Inc | Sub-type selective azabicycloalkane derivatives |
| JP5595926B2 (ja) | 2007-12-07 | 2014-09-24 | アボット ゲーエムベーハー ウント カンパニー カーゲー | ５−ハロゲン−置換オキシインドール誘導体およびバソプレッシン依存性疾患の治療へのこれらの使用 |
| CN101981027B (zh) | 2007-12-07 | 2014-08-06 | Abbvie德国有限责任两合公司 | 氨基甲基取代的羟吲哚衍生物及其用于治疗加压素依赖性疾病的用途 |
| EP2623504A1 (de) | 2007-12-07 | 2013-08-07 | Abbott GmbH & Co. KG | 5,6-Disubstituierte Oxindol-Derivate und ihre Verwendung zur Herstellung eines Medikaments zur Behandlung von Vasopressin-abhängigen Erkrankungen |
| WO2010009775A1 (de) | 2007-12-07 | 2010-01-28 | Abbott Gmbh & Co. Kg | Carbamat-substituierte oxindol-derivate und ihre verwendung zur behandlung von vasopressin-abhängigen erkrankungen |
| AU2009313920B2 (en) * | 2008-11-14 | 2014-10-23 | Boehringer Ingelheim Animal Health USA Inc. | Enantiomerically enriched aryloazol- 2 -yl cyanoethylamino paraciticidal compounds |
| US9040568B2 (en) | 2009-05-29 | 2015-05-26 | Abbvie Inc. | Pharmaceutical compositions for the treatment of pain |
| US8697691B2 (en) * | 2009-12-21 | 2014-04-15 | Vanderbilt University | Alkyl 3-((2-amidoethyl)amino)-8-azabicyclo[3.2.1]octane-8-carboxylate analogs as selective M1 agonists and methods of making and using same |
| CA2824350C (en) * | 2011-02-25 | 2019-07-02 | Janssen Pharmaceutica Nv | (pyridin-4-yl)benzylamides as allosteric modulators of alpha 7 nachr |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6518423B1 (en) * | 1996-08-09 | 2003-02-11 | Eisai Co., Ltd. | Benzopiperidine derivatives |
| JP2003516988A (ja) * | 1999-12-14 | 2003-05-20 | ニューロサーチ、アクティーゼルスカブ | 新規ヘテロアリール−ジアザビシクロアルカン類 |
| ATE341548T1 (de) * | 2001-07-06 | 2006-10-15 | Neurosearch As | Neue verbindungen, deren herstellung und verwendung |
| AU2004282201A1 (en) * | 2003-10-15 | 2005-04-28 | Targacept, Inc. | Azabicycyclic compounds for relieving pain and treating central nervous system disorders |
-
2006
- 2006-02-23 US US11/817,056 patent/US20080261999A1/en not_active Abandoned
- 2006-02-27 DE DE602006018713T patent/DE602006018713D1/de active Active
- 2006-02-27 ES ES06721069T patent/ES2354905T3/es active Active
- 2006-02-27 WO PCT/US2006/006756 patent/WO2006096358A1/en active Application Filing
- 2006-02-27 EP EP06721069A patent/EP1858857B1/de not_active Not-in-force
- 2006-02-27 AT AT06721069T patent/ATE490958T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1858857A1 (de) | 2007-11-28 |
| EP1858857B1 (de) | 2010-12-08 |
| DE602006018713D1 (de) | 2011-01-20 |
| WO2006096358A1 (en) | 2006-09-14 |
| ES2354905T3 (es) | 2011-03-21 |
| US20080261999A1 (en) | 2008-10-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE490958T1 (de) | Als agonisten für den nikotinischen acetylcholinrezeptor geeignete azabicycloalkanderivate | |
| NO20090628L (no) | Pyridizinon derivativater | |
| EP1962838A4 (de) | Farnesoid-x-rezeptor-agonisten | |
| EA200870193A1 (ru) | Цитотоксические агенты, включающие новые производные томаймицина, и их терапевтическое применение | |
| ME01488B (me) | Derivati oksadiazola i njihovo korišćenje kao potencijatora metabotropnih glutamatnih receptora-842 | |
| NO20083630L (no) | Nye pyridinderivater | |
| EA017278B9 (ru) | Соединения азаиндазола и способы применения | |
| EA200870217A1 (ru) | 4-арил-2-аминопиримидины или 4-арил-2-аминоалкилпиримидины в качестве модуляторов jak-2 и содержащие их фармацевтические композиции | |
| BRPI0605921B8 (pt) | compostos orgânicos, seus métodos de preparo e uso, bem como composições farmacêuticas | |
| UY30183A1 (es) | Derivados de quinolina | |
| TW200613243A (en) | Novel compounds | |
| NO20074441L (no) | 1-benzylindol-2-karboksamidderivater | |
| TNSN08326A1 (en) | Azacyclyl-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments | |
| UA96277C2 (en) | Benzimidazole derivatives | |
| HK1120442A1 (en) | Novel opioid antagonists | |
| TW200639156A (en) | New compounds | |
| EA200970585A1 (ru) | Бензамидные производные как агонисты ер-рецепторов | |
| UA92670C2 (ru) | Пиразолиновые соединения и их фармацевтическое применение, композиция на их основе | |
| ATE496918T1 (de) | Als a2b-adenosinrezeptorantagonisten geeignete 5- phenyl-6-pyridin-4-yl-1,3-dihydro-2h-imidazoä4, - büpyridin-2-onderivate | |
| TW200740776A (en) | N-phenylbenzotriazolyl c-kit inhibitors | |
| CY1109916T1 (el) | Βενζιμιδαζολο-θειοφαινικες ενωσεις ως plk αναστολεις | |
| NO20081001L (no) | Derivater av karboksamid som antagonister for muskarinisk reseptor | |
| ATE466842T1 (de) | 3-substituierte pyridinderivate als h3- antagonisten | |
| MY149854A (en) | Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments | |
| UA93709C2 (ru) | 12-имидазолил-1-додеканол и его применение b изготовлении фармацевтических композиций |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |