UA78014C2 - Macrocyclic peptides active against hepatitis c virus - Google Patents
Macrocyclic peptides active against hepatitis c virus Download PDFInfo
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- UA78014C2 UA78014C2 UA20040807068A UA20040807068A UA78014C2 UA 78014 C2 UA78014 C2 UA 78014C2 UA 20040807068 A UA20040807068 A UA 20040807068A UA 20040807068 A UA20040807068 A UA 20040807068A UA 78014 C2 UA78014 C2 UA 78014C2
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- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002369711A CA2369711A1 (en) | 2002-01-30 | 2002-01-30 | Macrocyclic peptides active against the hepatitis c virus |
| PCT/CA2003/000089 WO2003064455A2 (en) | 2002-01-30 | 2003-01-24 | Macrocyclic peptides active against the hepatitis c virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA78014C2 true UA78014C2 (en) | 2007-02-15 |
Family
ID=27626541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA20040807068A UA78014C2 (en) | 2002-01-30 | 2003-01-24 | Macrocyclic peptides active against hepatitis c virus |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US20030181363A1 (zh) |
| EP (1) | EP1472278B1 (zh) |
| JP (1) | JP4040578B2 (zh) |
| KR (1) | KR20040077899A (zh) |
| CN (1) | CN1639187A (zh) |
| AR (1) | AR038330A1 (zh) |
| AT (1) | ATE414098T1 (zh) |
| BR (1) | BR0307297A (zh) |
| CA (1) | CA2369711A1 (zh) |
| DE (1) | DE60324660D1 (zh) |
| EA (1) | EA007738B1 (zh) |
| EC (1) | ECSP045243A (zh) |
| ES (1) | ES2316718T3 (zh) |
| HR (1) | HRP20040689A2 (zh) |
| MX (1) | MXPA04007462A (zh) |
| NO (1) | NO20043591L (zh) |
| NZ (1) | NZ534929A (zh) |
| PE (1) | PE20030818A1 (zh) |
| PL (1) | PL371007A1 (zh) |
| RS (1) | RS67004A (zh) |
| SA (1) | SA03230569B1 (zh) |
| TW (1) | TW200307692A (zh) |
| UA (1) | UA78014C2 (zh) |
| UY (1) | UY27630A1 (zh) |
| WO (1) | WO2003064455A2 (zh) |
| ZA (1) | ZA200405639B (zh) |
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| AU2003299519A1 (en) | 2002-05-20 | 2004-05-04 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
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| ES2350201T3 (es) | 2002-05-20 | 2011-01-20 | Bristol-Myers Squibb Company | Sulfamidas heterocíclicas como inhibidores del virus de la hepatitis c. |
| US20050075279A1 (en) * | 2002-10-25 | 2005-04-07 | Boehringer Ingelheim International Gmbh | Macrocyclic peptides active against the hepatitis C virus |
| US20050159345A1 (en) * | 2002-10-29 | 2005-07-21 | Boehringer Ingelheim International Gmbh | Composition for the treatment of infection by Flaviviridae viruses |
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| CL2004001161A1 (es) | 2003-05-21 | 2005-04-08 | Boehringer Ingelheim Int | Compuestos describe compuestos derivados de quinolina; composicion farmaceutica; y su uso para tratar una enfermedad causada por el virus de la hepatitis c. |
| WO2004111077A1 (en) | 2003-06-18 | 2004-12-23 | Tranzyme Pharma Inc. | Macrocyclic antagonists of the motilin receptor |
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| EA200600498A1 (ru) * | 2003-09-22 | 2006-10-27 | Бёрингер Ингельхайм Интернациональ Гмбх | Макроциклические пептиды, проявляющие противовирусную активность в отношении вируса гепатита с |
| ES2398912T3 (es) | 2003-10-14 | 2013-03-22 | F. Hoffmann-La Roche Ltd. | Ácido carboxílico macrocíclico y compuesto de acilsulfonamida como inhibidor de la replicación del virus de la hepatitis C |
| US7491794B2 (en) * | 2003-10-14 | 2009-02-17 | Intermune, Inc. | Macrocyclic compounds as inhibitors of viral replication |
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| ATE424926T1 (de) * | 2003-12-08 | 2009-03-15 | Boehringer Ingelheim Int | Abtrennung von ruthenium-nebenprodukten durch behandlung mit überkritischen flüssigkeiten |
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|---|---|---|---|---|
| UA74546C2 (en) * | 1999-04-06 | 2006-01-16 | Boehringer Ingelheim Ca Ltd | Macrocyclic peptides having activity relative to hepatitis c virus, a pharmaceutical composition and use of the pharmaceutical composition |
| US6608027B1 (en) * | 1999-04-06 | 2003-08-19 | Boehringer Ingelheim (Canada) Ltd | Macrocyclic peptides active against the hepatitis C virus |
| US6867185B2 (en) * | 2001-12-20 | 2005-03-15 | Bristol-Myers Squibb Company | Inhibitors of hepatitis C virus |
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2002
- 2002-01-30 CA CA002369711A patent/CA2369711A1/en not_active Abandoned
- 2002-12-17 US US10/320,978 patent/US20030181363A1/en not_active Abandoned
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- 2003-01-24 NZ NZ534929A patent/NZ534929A/en unknown
- 2003-01-24 AT AT03700743T patent/ATE414098T1/de active
- 2003-01-24 UA UA20040807068A patent/UA78014C2/uk unknown
- 2003-01-24 PL PL03371007A patent/PL371007A1/xx not_active Application Discontinuation
- 2003-01-24 WO PCT/CA2003/000089 patent/WO2003064455A2/en active Application Filing
- 2003-01-24 CN CNA038054841A patent/CN1639187A/zh active Pending
- 2003-01-24 DE DE60324660T patent/DE60324660D1/de not_active Expired - Lifetime
- 2003-01-24 KR KR10-2004-7011682A patent/KR20040077899A/ko not_active Application Discontinuation
- 2003-01-24 MX MXPA04007462A patent/MXPA04007462A/es unknown
- 2003-01-24 EA EA200400886A patent/EA007738B1/ru not_active IP Right Cessation
- 2003-01-24 ES ES03700743T patent/ES2316718T3/es not_active Expired - Lifetime
- 2003-01-24 EP EP03700743A patent/EP1472278B1/en not_active Expired - Lifetime
- 2003-01-24 BR BR0307297-5A patent/BR0307297A/pt not_active IP Right Cessation
- 2003-01-24 RS YU67004A patent/RS67004A/sr unknown
- 2003-01-28 TW TW092101813A patent/TW200307692A/zh unknown
- 2003-01-29 PE PE2003000095A patent/PE20030818A1/es not_active Application Discontinuation
- 2003-01-29 AR ARP030100252A patent/AR038330A1/es unknown
- 2003-01-29 UY UY27630A patent/UY27630A1/es not_active Application Discontinuation
- 2003-03-02 SA SA03230569A patent/SA03230569B1/ar unknown
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2004
- 2004-07-15 ZA ZA200405639A patent/ZA200405639B/en unknown
- 2004-07-29 HR HR20040689A patent/HRP20040689A2/hr not_active Application Discontinuation
- 2004-08-20 EC EC2004005243A patent/ECSP045243A/es unknown
- 2004-08-27 NO NO20043591A patent/NO20043591L/no not_active Application Discontinuation
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|---|---|
| UY27630A1 (es) | 2003-08-29 |
| EA200400886A1 (ru) | 2005-02-24 |
| NZ534929A (en) | 2006-08-31 |
| PL371007A1 (en) | 2005-06-13 |
| BR0307297A (pt) | 2004-12-21 |
| CN1639187A (zh) | 2005-07-13 |
| TW200307692A (en) | 2003-12-16 |
| DE60324660D1 (de) | 2008-12-24 |
| WO2003064455A2 (en) | 2003-08-07 |
| JP4040578B2 (ja) | 2008-01-30 |
| PE20030818A1 (es) | 2003-10-30 |
| WO2003064455A3 (en) | 2004-02-05 |
| EA007738B1 (ru) | 2006-12-29 |
| EP1472278B1 (en) | 2008-11-12 |
| US20030181363A1 (en) | 2003-09-25 |
| ZA200405639B (en) | 2005-07-01 |
| EP1472278A2 (en) | 2004-11-03 |
| SA03230569B1 (ar) | 2007-03-05 |
| RS67004A (en) | 2006-10-27 |
| MXPA04007462A (es) | 2005-07-13 |
| JP2005524632A (ja) | 2005-08-18 |
| AR038330A1 (es) | 2005-01-12 |
| ATE414098T1 (de) | 2008-11-15 |
| CA2369711A1 (en) | 2003-07-30 |
| ES2316718T3 (es) | 2009-04-16 |
| NO20043591L (no) | 2004-08-27 |
| KR20040077899A (ko) | 2004-09-07 |
| ECSP045243A (es) | 2004-09-28 |
| HRP20040689A2 (en) | 2005-06-30 |
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