UA77778C2 - Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexanes as nmda, 5ht3, and nicotinic receptor antagonists - Google Patents
Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexanes as nmda, 5ht3, and nicotinic receptor antagonists Download PDFInfo
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- UA77778C2 UA77778C2 UA20041008550A UA20041008550A UA77778C2 UA 77778 C2 UA77778 C2 UA 77778C2 UA 20041008550 A UA20041008550 A UA 20041008550A UA 20041008550 A UA20041008550 A UA 20041008550A UA 77778 C2 UA77778 C2 UA 77778C2
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| US36638602P | 2002-03-21 | 2002-03-21 | |
| PCT/GB2003/001236 WO2003080046A1 (en) | 2002-03-21 | 2003-03-21 | Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane nmda, 5ht3, and neuronal nicotinic receptor antagoni sts |
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| UA77778C2 true UA77778C2 (en) | 2007-01-15 |
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| CN101389315A (zh) | 2004-06-17 | 2009-03-18 | 莫茨药物股份两合公司 | 美金刚口服剂型即释制剂 |
| US20060205822A1 (en) * | 2004-12-22 | 2006-09-14 | Forest Laboratories, Inc. | 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect |
| EP2111858A1 (en) | 2008-04-25 | 2009-10-28 | EPFL Ecole Polytechnique Fédérale de Lausanne | Novel treatment for alzheimer's disease |
| US20090275597A1 (en) * | 2008-05-02 | 2009-11-05 | Forest Laboratories Holdings Limited | Methods of treating cns disorders |
| US8809397B2 (en) | 2010-05-27 | 2014-08-19 | Targacept, Inc. | Nicotinic receptor non-competitive antagonists |
| MX2014005216A (es) * | 2011-11-03 | 2014-08-22 | Targacept Inc | Moduladores no competitivos de receptores nicotinicos. |
| JP6095122B2 (ja) * | 2012-01-25 | 2017-03-15 | 国立大学法人東北大学 | 脳機能改善剤 |
| NZ710034A (en) | 2013-03-14 | 2020-06-26 | Boehringer Ingelheim Int | Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c |
| DK3191487T3 (da) | 2014-09-12 | 2019-10-28 | Boehringer Ingelheim Int | Spirocykliske cathepsin-c-inhibitorer |
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| GB1153973A (en) | 1966-03-14 | 1969-06-04 | Upjohn Co | alpha,alpha-Diphenyl-beta-Methyl-1-Azaspiro[4,5]Decane (and [4,4]Nonane)-1-Propanols |
| GB1472334A (en) | 1973-07-14 | 1977-05-04 | Tanabe Seiyaku Co | 1-3-hydroxyphenyl-6-azabicyclo-3,2,1-octane derivatives and their use in pharmaceutical preparations |
| IL59553A0 (en) | 1979-03-12 | 1980-06-30 | Lilly Co Eli | Phenylmorphans,intermediates and method for their preparation |
| DE3132020A1 (de) | 1981-08-13 | 1983-03-03 | Basf Ag, 6700 Ludwigshafen | N-benzoyl-n'-phenylharnstoffe, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von insekten und spinnentieren |
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| JP3134952B2 (ja) * | 1991-09-18 | 2001-02-13 | 東洋紡績株式会社 | 難撚性ポリエステル樹脂組成物の製造方法 |
| FR2693462B1 (fr) | 1992-07-08 | 1994-09-30 | Cepbepe | Préparation de nouveaux dérivés amido-alcools et leurs applications en thérapeutique. |
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| AU7125096A (en) * | 1995-09-22 | 1997-04-09 | Novo Nordisk A/S | Novel substituted azacyclic or azabicyclic compounds |
| US5900227A (en) * | 1996-06-17 | 1999-05-04 | Oklahoma Medical Research Foundation | Multicyclic nitrone spin trapping compositions |
| EP1133494B1 (en) | 1998-11-27 | 2004-02-18 | Neurosearch A/S | 8-azabicyclo 3.2.1]oct-2-ene and -octane derivatives |
| TW593223B (en) | 2000-06-20 | 2004-06-21 | Merz Pharma Gmbh & Co Kgaa | 1-amino-alkylcyclohexanes as 5-HT3 and neuronal nicotinic receptor antagonists |
| US6951961B2 (en) * | 2002-05-17 | 2005-10-04 | Marina Nikolaevna Protopopova | Methods of use and compositions for the diagnosis and treatment of infectious disease |
-
2003
- 2003-03-17 TW TW092105796A patent/TW200306189A/zh unknown
- 2003-03-18 AR ARP030100948A patent/AR039008A1/es unknown
- 2003-03-21 MX MXPA04007755A patent/MXPA04007755A/es not_active Application Discontinuation
- 2003-03-21 JP JP2003577874A patent/JP4262606B2/ja not_active Expired - Fee Related
- 2003-03-21 WO PCT/GB2003/001236 patent/WO2003080046A1/en active IP Right Grant
- 2003-03-21 US US10/394,670 patent/US7022729B2/en not_active Expired - Fee Related
- 2003-03-21 EP EP03712394A patent/EP1485086A1/en not_active Withdrawn
- 2003-03-21 GE GEAP8454A patent/GEP20063954B/en unknown
- 2003-03-21 PL PL03372701A patent/PL372701A1/xx not_active Application Discontinuation
- 2003-03-21 EA EA200401230A patent/EA007098B1/ru unknown
- 2003-03-21 CA CA002474637A patent/CA2474637A1/en not_active Abandoned
- 2003-03-21 IL IL16404103A patent/IL164041A0/xx unknown
- 2003-03-21 KR KR1020047011982A patent/KR100741257B1/ko not_active IP Right Cessation
- 2003-03-21 CN CNA038044900A patent/CN1638762A/zh active Pending
- 2003-03-21 UA UA20041008550A patent/UA77778C2/uk unknown
- 2003-03-21 AU AU2003216855A patent/AU2003216855B2/en not_active Ceased
-
2004
- 2004-08-31 ZA ZA200406940A patent/ZA200406940B/en unknown
- 2004-08-31 CO CO04085290A patent/CO5611104A2/es not_active Application Discontinuation
- 2004-10-20 NO NO20044481A patent/NO20044481L/no not_active Application Discontinuation
-
2005
- 2005-08-11 US US11/202,012 patent/US7238703B2/en not_active Expired - Fee Related
- 2005-08-11 US US11/202,115 patent/US20060019983A1/en not_active Abandoned
-
2007
- 2007-04-04 US US11/732,764 patent/US20070185151A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP4262606B2 (ja) | 2009-05-13 |
| TW200306189A (en) | 2003-11-16 |
| PL372701A1 (en) | 2005-07-25 |
| US7238703B2 (en) | 2007-07-03 |
| CA2474637A1 (en) | 2003-10-02 |
| EP1485086A1 (en) | 2004-12-15 |
| KR20040091005A (ko) | 2004-10-27 |
| EA200401230A1 (ru) | 2005-02-24 |
| ZA200406940B (en) | 2005-09-22 |
| CO5611104A2 (es) | 2006-02-28 |
| EA007098B1 (ru) | 2006-06-30 |
| US20040034055A1 (en) | 2004-02-19 |
| US20060019983A1 (en) | 2006-01-26 |
| JP2005525385A (ja) | 2005-08-25 |
| AU2003216855B2 (en) | 2005-08-18 |
| US20070185151A1 (en) | 2007-08-09 |
| MXPA04007755A (es) | 2004-10-15 |
| US20060019982A1 (en) | 2006-01-26 |
| IL164041A0 (en) | 2005-12-18 |
| WO2003080046A1 (en) | 2003-10-02 |
| GEP20063954B (en) | 2006-10-25 |
| US7022729B2 (en) | 2006-04-04 |
| AR039008A1 (es) | 2005-02-02 |
| NO20044481L (no) | 2004-10-20 |
| AU2003216855A1 (en) | 2003-10-08 |
| CN1638762A (zh) | 2005-07-13 |
| KR100741257B1 (ko) | 2007-07-19 |
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