UA75064C2 - Modified porcine factor viii and its therapeutic use - Google Patents

Modified porcine factor viii and its therapeutic use Download PDF

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Publication number
UA75064C2
UA75064C2 UA2002097145A UA2002097145A UA75064C2 UA 75064 C2 UA75064 C2 UA 75064C2 UA 2002097145 A UA2002097145 A UA 2002097145A UA 2002097145 A UA2002097145 A UA 2002097145A UA 75064 C2 UA75064 C2 UA 75064C2
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UA
Ukraine
Prior art keywords
factor
human
pig
domain
porcine
Prior art date
Application number
UA2002097145A
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English (en)
Ukrainian (uk)
Original Assignee
Univ Emory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Univ Emory filed Critical Univ Emory
Publication of UA75064C2 publication Critical patent/UA75064C2/uk

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/10Factor VIII, AHF; related peptides
UA2002097145A 2000-03-10 2001-02-16 Modified porcine factor viii and its therapeutic use UA75064C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/523,656 US6458563B1 (en) 1996-06-26 2000-03-10 Modified factor VIII
PCT/US2001/005076 WO2001068109A1 (en) 2000-03-10 2001-02-16 Modified factor viii

Publications (1)

Publication Number Publication Date
UA75064C2 true UA75064C2 (en) 2006-03-15

Family

ID=24085870

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2002097145A UA75064C2 (en) 2000-03-10 2001-02-16 Modified porcine factor viii and its therapeutic use

Country Status (36)

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US (3) US6458563B1 (de)
EP (1) EP1280540B1 (de)
JP (1) JP4044337B2 (de)
KR (1) KR100485525B1 (de)
CN (1) CN1191360C (de)
AT (1) ATE391512T1 (de)
AU (2) AU3841601A (de)
BE (1) BE2016C024I2 (de)
BR (2) BRPI0109131B8 (de)
CA (1) CA2400295C (de)
CY (2) CY1108179T1 (de)
CZ (1) CZ298250B6 (de)
DE (1) DE60133541T2 (de)
DK (1) DK1280540T3 (de)
EE (1) EE05075B1 (de)
ES (1) ES2304379T3 (de)
FR (1) FR16C0016I2 (de)
HK (1) HK1051004A1 (de)
HU (2) HU227804B1 (de)
IL (2) IL151371A0 (de)
LT (1) LTC1280540I2 (de)
LU (1) LU93049I2 (de)
ME (1) MEP8209A (de)
MX (1) MXPA02008798A (de)
NL (1) NL300808I2 (de)
NO (2) NO331935B1 (de)
NZ (1) NZ520799A (de)
PL (1) PL202936B1 (de)
PT (1) PT1280540E (de)
RS (1) RS50364B (de)
RU (1) RU2285724C2 (de)
SI (1) SI1280540T1 (de)
SK (1) SK286205B6 (de)
UA (1) UA75064C2 (de)
WO (1) WO2001068109A1 (de)
ZA (1) ZA200206810B (de)

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JP4044337B2 (ja) 2008-02-06
NO20024296D0 (no) 2002-09-09
RU2285724C2 (ru) 2006-10-20
LTC1280540I2 (lt) 2020-05-25
CY2016011I2 (el) 2016-10-05
NZ520799A (en) 2004-06-25
IL151371A0 (en) 2003-04-10
CY2016011I1 (el) 2016-10-05
BRPI0109131B1 (pt) 2020-08-25
AU3841601A (en) 2001-09-24
NL300808I2 (nl) 2020-12-21
SK14392002A3 (sk) 2003-06-03
SK286205B6 (sk) 2008-05-06
EE200200510A (et) 2004-02-16
HUP0300586A2 (hu) 2003-06-28
HUS1600020I1 (hu) 2016-06-28
BE2016C024I2 (de) 2020-01-30
DE60133541D1 (de) 2008-05-21
RU2002124123A (ru) 2004-03-27
SI1280540T1 (sl) 2008-08-31
KR20020081426A (ko) 2002-10-26
CA2400295C (en) 2012-01-10
US7012132B2 (en) 2006-03-14
EE05075B1 (et) 2008-10-15
HU227804B1 (en) 2012-03-28
HUP0300586A3 (en) 2006-11-28
HK1051004A1 (en) 2003-07-18
YU68002A (sh) 2005-11-28
BR122013026957A2 (de) 2004-12-07
CZ298250B6 (cs) 2007-08-01
US6458563B1 (en) 2002-10-01
CZ20023346A3 (cs) 2003-01-15
PT1280540E (pt) 2008-06-09
CA2400295A1 (en) 2001-09-20
LU93049I2 (fr) 2016-06-27
IL151371A (en) 2010-12-30
WO2001068109A1 (en) 2001-09-20
BR0109131A (pt) 2004-12-07
NO20024296L (no) 2002-11-08
US20030068785A1 (en) 2003-04-10
US20050079584A1 (en) 2005-04-14
ZA200206810B (en) 2003-11-26
NO331935B1 (no) 2012-05-07
AU2001238416B2 (en) 2004-09-02
DE60133541T2 (de) 2009-05-07
JP2003526358A (ja) 2003-09-09
ME00601B (me) 2011-12-20
NL300808I1 (de) 2016-05-18
FR16C0016I1 (de) 2016-04-29
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BRPI0109131B8 (pt) 2021-07-06
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EP1280540A1 (de) 2003-02-05
MXPA02008798A (es) 2003-04-25
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