UA73125C2 - Похідні амінотіазолу, спосіб їх одержання, фармацевтична композиція та їх використання як лігандів рецептора crf - Google Patents
Похідні амінотіазолу, спосіб їх одержання, фармацевтична композиція та їх використання як лігандів рецептора crf Download PDFInfo
- Publication number
- UA73125C2 UA73125C2 UA2001129084A UA2001129084A UA73125C2 UA 73125 C2 UA73125 C2 UA 73125C2 UA 2001129084 A UA2001129084 A UA 2001129084A UA 2001129084 A UA2001129084 A UA 2001129084A UA 73125 C2 UA73125 C2 UA 73125C2
- Authority
- UA
- Ukraine
- Prior art keywords
- methylphenyl
- alkyl
- methylthiazol
- methoxy
- hydrochloride
- Prior art date
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- 238000000034 method Methods 0.000 title claims description 36
- 239000008194 pharmaceutical composition Substances 0.000 title claims description 9
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
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- Diabetes (AREA)
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- Immunology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Child & Adolescent Psychology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9909144A FR2796380B3 (fr) | 1999-07-15 | 1999-07-15 | Nouveaux derives d'aminothiazoles, leur preparation et les compositions pharmaceutiques les contenant |
| PCT/FR2000/001995 WO2001005776A1 (fr) | 1999-07-15 | 2000-07-11 | Derives d'aminothiazole et leur utilisation comme ligands des recepteurs crf |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA73125C2 true UA73125C2 (uk) | 2005-06-15 |
Family
ID=9548107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2001129084A UA73125C2 (uk) | 1999-07-15 | 2000-11-07 | Похідні амінотіазолу, спосіб їх одержання, фармацевтична композиція та їх використання як лігандів рецептора crf |
Country Status (36)
| Country | Link |
|---|---|
| US (2) | US6586456B1 (sk) |
| EP (1) | EP1200419B1 (sk) |
| JP (1) | JP4949582B2 (sk) |
| KR (1) | KR100707320B1 (sk) |
| CN (1) | CN1167692C (sk) |
| AR (1) | AR024747A1 (sk) |
| AT (1) | ATE264315T1 (sk) |
| AU (1) | AU772683B2 (sk) |
| BR (1) | BR0012478B1 (sk) |
| CA (1) | CA2378792C (sk) |
| CO (1) | CO5200792A1 (sk) |
| CZ (1) | CZ300937B6 (sk) |
| DE (1) | DE60009911T2 (sk) |
| DK (1) | DK1200419T3 (sk) |
| EA (1) | EA005159B1 (sk) |
| EE (1) | EE05004B1 (sk) |
| ES (1) | ES2220504T3 (sk) |
| FR (1) | FR2796380B3 (sk) |
| HK (1) | HK1045692B (sk) |
| HU (1) | HU229069B1 (sk) |
| IL (2) | IL147282A0 (sk) |
| IS (1) | IS2314B (sk) |
| ME (1) | MEP26608A (sk) |
| MX (1) | MXPA02000545A (sk) |
| NO (1) | NO324352B1 (sk) |
| NZ (1) | NZ516397A (sk) |
| PL (1) | PL206515B1 (sk) |
| PT (1) | PT1200419E (sk) |
| RS (1) | RS50443B (sk) |
| SI (1) | SI1200419T1 (sk) |
| SK (1) | SK287069B6 (sk) |
| TR (1) | TR200200125T2 (sk) |
| TW (1) | TWI278453B (sk) |
| UA (1) | UA73125C2 (sk) |
| WO (1) | WO2001005776A1 (sk) |
| ZA (1) | ZA200200221B (sk) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001296255B2 (en) * | 2000-09-21 | 2005-07-28 | Bristol-Myers Squibb Company | Substituted azole derivatives as inhibitors of corticotropin releasing factor |
| WO2003015777A1 (en) * | 2001-08-13 | 2003-02-27 | Lion Bioscience Ag | Nr1h4 nuclear receptor binding compounds |
| WO2003033128A2 (en) | 2001-10-12 | 2003-04-24 | Duke University | Methods for image analysis of high-density synthetic dna microarrays |
| EP2270034A3 (en) | 2004-06-03 | 2011-06-01 | Athlomics Pty Ltd | Agents and methods for diagnosing stress |
| CA2575466A1 (en) * | 2004-08-13 | 2006-02-23 | Genentech, Inc. | Thiazole based inhibitors of atp-utilizing enzymes |
| EP1834641A1 (en) * | 2006-03-16 | 2007-09-19 | Sanofi-Aventis | Use of CRF1 receptor antagonists for preparing a drug for treating metabolic syndrome and/or obesity and/or dyslipoproteinemia |
| HUP0900267A2 (en) * | 2009-04-30 | 2011-03-28 | Sanofi Aventis | Process for preparing of thiazole amines and intermediates thereof |
| US20150094310A1 (en) * | 2012-04-23 | 2015-04-02 | Holsboermaschmeyer Neurochemie Gmbh | Crhr1 antagonists for use in the treatment of patients having crh overactivity |
| GB201210686D0 (en) | 2012-06-15 | 2012-08-01 | Holsboermaschmeyer Neurochemie Gmbh | V1B receptor antagonist for use in the treatment of patients having an elevated AVP level and/or an elevated copeptin level |
| GB201310782D0 (en) | 2013-06-17 | 2013-07-31 | Max Planck Innovation Gmbh | Method for predicting a treatment response to a CRHR1 antagonist and/or V1B antagonist in a patient with depressive and/or anxiety symptoms |
| IL296683B2 (en) | 2014-01-21 | 2023-12-01 | Neurocrine Biosciences Inc | Preparations for the treatment of congenital adrenal hyperplasia |
| CA3121920A1 (en) * | 2018-12-07 | 2020-06-11 | Neurocrine Biosciences, Inc. | Crf1 receptor antagonist, pharmaceutical formulations and solid forms thereof for the treatment of congenital adrenal hyperplasia |
| JP7532328B2 (ja) * | 2018-12-07 | 2024-08-13 | ニューロクライン バイオサイエンシーズ，インコーポレイテッド | 先天性副腎過形成を処置するためのｃｒｆ１受容体アンタゴニスト、その医薬製剤および固体形態 |
| EP4034111A1 (en) * | 2019-09-27 | 2022-08-03 | Neurocrine Biosciences, Inc. | Crf receptor antagonists and methods of use |
| KR20230038458A (ko) | 2020-06-10 | 2023-03-20 | 뉴로크린 바이오사이언시즈 인코퍼레이티드 | 선천성 부신 증식증의 치료를 위한 crf1 수용체 길항제 |
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| FR2692893B1 (fr) * | 1992-06-24 | 1994-09-02 | Sanofi Elf | Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
| FR2714059B1 (fr) | 1993-12-21 | 1996-03-08 | Sanofi Elf | Dérivés amino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
| FR2735777B1 (fr) * | 1995-06-21 | 1997-09-12 | Sanofi Sa | Derives de 4-phenylaminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
| FR2754258B1 (fr) | 1996-10-08 | 1998-12-31 | Sanofi Sa | Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
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2001
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2002
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2007
- 2007-04-25 US US11/740,001 patent/US8420679B2/en not_active Expired - Lifetime
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