UA54481C2 - Сполуки з аналгезивною дією, спосіб їх отримання, фармакологічна композиція та діагностичний агент на їхній основі - Google Patents

Сполуки з аналгезивною дією, спосіб їх отримання, фармакологічна композиція та діагностичний агент на їхній основі Download PDF

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Publication number
UA54481C2
UA54481C2 UA99074131A UA99074131A UA54481C2 UA 54481 C2 UA54481 C2 UA 54481C2 UA 99074131 A UA99074131 A UA 99074131A UA 99074131 A UA99074131 A UA 99074131A UA 54481 C2 UA54481 C2 UA 54481C2
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UA
Ukraine
Prior art keywords
compound
formula
сно
independently
defined above
Prior art date
Application number
UA99074131A
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English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Бенджамін Пелкман
Едвард Робертс
Original Assignee
Астра Фарма Інк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Астра Фарма Інк. filed Critical Астра Фарма Інк.
Publication of UA54481C2 publication Critical patent/UA54481C2/uk

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0446Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14Nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
UA99074131A 1996-12-20 1997-09-12 Сполуки з аналгезивною дією, спосіб їх отримання, фармакологічна композиція та діагностичний агент на їхній основі UA54481C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9604786A SE9604786D0 (sv) 1996-12-20 1996-12-20 New compounds
PCT/SE1997/002051 WO1998028270A1 (en) 1996-12-20 1997-12-09 Novel compounds with analgesic effect

Publications (1)

Publication Number Publication Date
UA54481C2 true UA54481C2 (uk) 2003-03-17

Family

ID=20405139

Family Applications (1)

Application Number Title Priority Date Filing Date
UA99074131A UA54481C2 (uk) 1996-12-20 1997-09-12 Сполуки з аналгезивною дією, спосіб їх отримання, фармакологічна композиція та діагностичний агент на їхній основі

Country Status (31)

Country Link
US (3) US6153626A (https=)
EP (2) EP0946510B1 (https=)
JP (1) JP2001507021A (https=)
KR (1) KR20000069600A (https=)
CN (2) CN1539824A (https=)
AR (1) AR010378A1 (https=)
AT (1) ATE266638T1 (https=)
AU (1) AU738002B2 (https=)
BR (1) BR9713785A (https=)
CA (1) CA2274117A1 (https=)
CZ (1) CZ220099A3 (https=)
DE (1) DE69729115T2 (https=)
DK (1) DK0946510T3 (https=)
EE (1) EE03966B1 (https=)
ES (1) ES2219783T3 (https=)
HU (1) HUP0000613A3 (https=)
ID (1) ID21662A (https=)
IL (1) IL130536A0 (https=)
IS (1) IS5078A (https=)
MY (1) MY132705A (https=)
NO (1) NO313632B1 (https=)
NZ (1) NZ336028A (https=)
PL (1) PL188945B1 (https=)
PT (1) PT946510E (https=)
RU (1) RU2193030C2 (https=)
SE (1) SE9604786D0 (https=)
SK (1) SK283300B6 (https=)
TR (1) TR199901411T2 (https=)
UA (1) UA54481C2 (https=)
WO (1) WO1998028270A1 (https=)
ZA (1) ZA9711049B (https=)

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EP1512683B1 (en) * 1998-03-10 2011-08-31 Research Triangle Institute Novel opiate compounds, methods of making and methods of use
US6900228B1 (en) 1998-03-10 2005-05-31 Research Triangle Institute Opiate compounds, methods of making and methods of use
US6436959B1 (en) 1998-12-23 2002-08-20 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)]aminobenzamides
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SE9904674D0 (sv) * 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
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SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
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US7741519B2 (en) 2007-04-23 2010-06-22 Chemocentryx, Inc. Bis-aryl sulfonamides
US6939885B2 (en) 2002-11-18 2005-09-06 Chemocentryx Aryl sulfonamides
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Also Published As

Publication number Publication date
HK1022910A1 (en) 2000-08-25
EP0946510A1 (en) 1999-10-06
NO993023L (no) 1999-08-12
ES2219783T3 (es) 2004-12-01
CN1539824A (zh) 2004-10-27
TR199901411T2 (xx) 1999-09-21
EP1428821A1 (en) 2004-06-16
EP1428821A8 (en) 2005-01-26
EE9900261A (et) 2000-02-15
BR9713785A (pt) 2000-02-08
ZA9711049B (en) 1998-06-22
AU738002B2 (en) 2001-09-06
AU5351398A (en) 1998-07-17
MY132705A (en) 2007-10-31
HUP0000613A3 (en) 2002-10-28
PT946510E (pt) 2004-08-31
HK1023996A1 (en) 2000-09-29
US20030055045A1 (en) 2003-03-20
DE69729115T2 (de) 2005-04-28
SK283300B6 (sk) 2003-05-02
NO313632B1 (no) 2002-11-04
ATE266638T1 (de) 2004-05-15
DK0946510T3 (da) 2004-08-09
ID21662A (id) 1999-07-08
NZ336028A (en) 2001-03-30
IS5078A (is) 1999-06-11
CZ220099A3 (cs) 1999-11-17
EE03966B1 (et) 2003-02-17
SK76399A3 (en) 2000-01-18
EP0946510B1 (en) 2004-05-12
WO1998028270A1 (en) 1998-07-02
KR20000069600A (ko) 2000-11-25
IL130536A0 (en) 2000-06-01
PL188945B1 (pl) 2005-05-31
JP2001507021A (ja) 2001-05-29
CA2274117A1 (en) 1998-07-02
AR010378A1 (es) 2000-06-07
US6399635B1 (en) 2002-06-04
PL334370A1 (en) 2000-02-28
US6153626A (en) 2000-11-28
CN1241178A (zh) 2000-01-12
HUP0000613A2 (hu) 2000-09-28
SE9604786D0 (sv) 1996-12-20
DE69729115D1 (de) 2004-06-17
RU2193030C2 (ru) 2002-11-20
US6710179B2 (en) 2004-03-23
NO993023D0 (no) 1999-06-18
CN1154635C (zh) 2004-06-23

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