TWI925812B - 用於製造腫瘤浸潤性淋巴細胞之方法及其在免疫療法中之用途 - Google Patents

用於製造腫瘤浸潤性淋巴細胞之方法及其在免疫療法中之用途

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Publication number
TWI925812B
TWI925812B TW108139990A TW108139990A TWI925812B TW I925812 B TWI925812 B TW I925812B TW 108139990 A TW108139990 A TW 108139990A TW 108139990 A TW108139990 A TW 108139990A TW I925812 B TWI925812 B TW I925812B
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Taiwan
Prior art keywords
amplification
preparatory
til
approximately
cancer
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TW108139990A
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English (en)
Chinese (zh)
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TW202039830A (zh
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賽斯 沃錐
馬里察 莫雷諾
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美商艾歐凡斯生物治療公司
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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    • A61K40/00—Cellular immunotherapy
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2302—Interleukin-2 (IL-2)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
    • C12N2502/1121—Dendritic cells

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  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
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  • Virology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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TW108139990A 2018-11-05 2019-11-04 用於製造腫瘤浸潤性淋巴細胞之方法及其在免疫療法中之用途 TWI925812B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862755954P 2018-11-05 2018-11-05
US62/755,954 2018-11-05
US201962903585P 2019-09-20 2019-09-20
US62/903,585 2019-09-20

Publications (2)

Publication Number Publication Date
TW202039830A TW202039830A (zh) 2020-11-01
TWI925812B true TWI925812B (zh) 2026-05-21

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US (3) US12453697B2 (enExample)
EP (1) EP3877513B1 (enExample)
JP (2) JP2022506586A (enExample)
KR (1) KR102957749B1 (enExample)
CN (1) CN113272421B (enExample)
AU (1) AU2019374761B2 (enExample)
BR (1) BR112021008573A2 (enExample)
CA (1) CA3118624A1 (enExample)
CL (1) CL2021001178A1 (enExample)
CO (1) CO2021007362A2 (enExample)
CR (1) CR20210295A (enExample)
ES (1) ES3036072T3 (enExample)
IL (1) IL282919A (enExample)
JO (1) JOP20210094A1 (enExample)
MX (1) MX2021005216A (enExample)
MY (1) MY210603A (enExample)
PE (1) PE20211292A1 (enExample)
PH (1) PH12021551033A1 (enExample)
SG (1) SG11202104615VA (enExample)
TW (1) TWI925812B (enExample)
WO (1) WO2020096988A2 (enExample)

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