TWI373343B - Antibodies that bind human interleukin-18 and methods of making and using - Google Patents

Antibodies that bind human interleukin-18 and methods of making and using Download PDF

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Publication number
TWI373343B
TWI373343B TW099121901A TW99121901A TWI373343B TW I373343 B TWI373343 B TW I373343B TW 099121901 A TW099121901 A TW 099121901A TW 99121901 A TW99121901 A TW 99121901A TW I373343 B TWI373343 B TW I373343B
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Taiwan
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antibody
ser
disease
human
gly
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TW099121901A
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English (en)
Chinese (zh)
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TW201036638A (en
Inventor
Tariq Ghayur
Richard W Dixon
Michael Roguska
Michael White
Boris Labkovsky
Jochen Salfeld
Alexander Robert Duncan
Simon Mark Brocklehurst
John Mankovich
Celia Patricia Shorrock
Julia Elizabeth Thompson
Simon Nicholas Lennard
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Abbott Gmbh & Co Kg
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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SK12942002A3 (sk) 2003-05-02
IL151044A0 (en) 2003-04-10
CA2399148A1 (en) 2001-08-16
US20100104563A1 (en) 2010-04-29
JP2004500086A (ja) 2004-01-08
JP2012139224A (ja) 2012-07-26
EP2332579A3 (en) 2011-09-21
NO20023788D0 (no) 2002-08-09
NO20023788L (no) 2002-10-09
AR077568A2 (es) 2011-09-07
CN102206277A (zh) 2011-10-05
ZA200206266B (en) 2003-11-06
EP2338515A3 (en) 2011-11-16
KR101111103B1 (ko) 2012-02-13
BR0108188A (pt) 2003-02-25
AU2006252098B2 (en) 2011-02-24
MXPA02007756A (es) 2004-09-10
EP2360184A2 (en) 2011-08-24
BG111004A (bg) 2011-11-30
AU2011201536A1 (en) 2011-04-28
EP1257585A2 (en) 2002-11-20
AU2006252098A1 (en) 2007-01-11
EP2332579A2 (en) 2011-06-15
BG107045A (bg) 2003-05-30
AU2001236807A1 (en) 2001-08-20
AU2011201536B2 (en) 2013-07-04
HUP0300423A2 (hu) 2003-06-28
CN1461310A (zh) 2003-12-10
AU2006252098B9 (en) 2011-04-14
KR20120011898A (ko) 2012-02-08
TW201305214A (zh) 2013-02-01
MY146017A (en) 2012-06-15
WO2001058956A2 (en) 2001-08-16
CN102504024A (zh) 2012-06-20
KR20110032012A (ko) 2011-03-29
KR20090078372A (ko) 2009-07-17
US20110008357A1 (en) 2011-01-13
NZ520392A (en) 2005-04-29
PL356836A1 (en) 2004-07-12
TW201036638A (en) 2010-10-16
HUP0300423A3 (en) 2008-07-28
CN1461310B (zh) 2013-06-12
CA2800450A1 (en) 2001-08-16
US20130101595A1 (en) 2013-04-25
WO2001058956A3 (en) 2002-03-07
EP2360184A3 (en) 2011-11-16
KR20030021153A (ko) 2003-03-12
IL206980A0 (en) 2010-12-30
TWI335336B (enExample) 2011-01-01
CL2012001063A1 (es) 2013-06-21
KR100951067B1 (ko) 2010-04-07
US7767207B2 (en) 2010-08-03
AR027404A1 (es) 2003-03-26

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