HUP0300423A3 - Antibodies that bind human interleukin-18 and methods of making and using - Google Patents
Antibodies that bind human interleukin-18 and methods of making and usingInfo
- Publication number
- HUP0300423A3 HUP0300423A3 HU0300423A HUP0300423A HUP0300423A3 HU P0300423 A3 HUP0300423 A3 HU P0300423A3 HU 0300423 A HU0300423 A HU 0300423A HU P0300423 A HUP0300423 A HU P0300423A HU P0300423 A3 HUP0300423 A3 HU P0300423A3
- Authority
- HU
- Hungary
- Prior art keywords
- antibodies
- making
- methods
- human interleukin
- bind human
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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Applications Claiming Priority (2)
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|---|---|---|---|
| US18160800P | 2000-02-10 | 2000-02-10 | |
| PCT/US2001/004170 WO2001058956A2 (en) | 2000-02-10 | 2001-02-09 | Antibodies that bind human interleukin-18 and methods of making and using |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0300423A2 HUP0300423A2 (hu) | 2003-06-28 |
| HUP0300423A3 true HUP0300423A3 (en) | 2008-07-28 |
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| HU0300423A HUP0300423A3 (en) | 2000-02-10 | 2001-02-09 | Antibodies that bind human interleukin-18 and methods of making and using |
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