TW514667B - Methods for production of recombinant plasmids - Google Patents
Methods for production of recombinant plasmids Download PDFInfo
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- TW514667B TW514667B TW085115998A TW85115998A TW514667B TW 514667 B TW514667 B TW 514667B TW 085115998 A TW085115998 A TW 085115998A TW 85115998 A TW85115998 A TW 85115998A TW 514667 B TW514667 B TW 514667B
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
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|---|---|---|---|
| US54805995A | 1995-10-17 | 1995-10-17 | |
| US56497395A | 1995-11-30 | 1995-11-30 |
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|---|---|
| TW514667B true TW514667B (en) | 2002-12-21 |
Family
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| TW085115998A TW514667B (en) | 1995-10-17 | 1996-12-24 | Methods for production of recombinant plasmids |
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| EP (1) | EP0856059B1 (enExample) |
| JP (1) | JPH11513562A (enExample) |
| AT (1) | ATE247713T1 (enExample) |
| AU (1) | AU7208896A (enExample) |
| CA (1) | CA2232234A1 (enExample) |
| DE (1) | DE69629576T2 (enExample) |
| TW (1) | TW514667B (enExample) |
| WO (1) | WO1997014805A2 (enExample) |
Families Citing this family (45)
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| BE1006085A3 (fr) * | 1992-07-31 | 1994-05-10 | Univ Bruxelles | Vecteur de clonage. |
| EP2180050B1 (en) * | 1998-05-07 | 2016-04-20 | Universite Libre De Bruxelles | Cytotoxin-based biological containment |
| AU1031900A (en) * | 1998-11-09 | 2000-05-29 | Genecare Development Aps | Novel plasmids for use in medicine and method of producing same |
| ES2286905T3 (es) | 1998-12-02 | 2007-12-01 | University Of Maryland, Baltimore | Sistema de estabilizacion de plasmidos para el suministro de antigenos. |
| US6413768B1 (en) | 1998-12-02 | 2002-07-02 | University Of Maryland | Expression plasmids |
| US8076130B2 (en) * | 1998-12-02 | 2011-12-13 | University Of Maryland, Baltimore | Plasmid maintenance system for antigen delivery |
| US6423545B1 (en) * | 1999-07-08 | 2002-07-23 | Albert Einstein College Of Medicine Of Yeshiva University | Unmarked deletion mutants of mycobacteria and methods of using same |
| EP1111061A1 (en) * | 1999-12-20 | 2001-06-27 | Universite Libre De Bruxelles | Double selection vector |
| US9012141B2 (en) | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
| CA2435956C (en) * | 2001-02-23 | 2012-07-10 | Universite Libre De Bruxelles | Method for the selection of recombinant clones comprising a sequence encoding an antidote protein to toxic molecule |
| US7396822B2 (en) | 2001-05-24 | 2008-07-08 | Vaxiion Therapeutics, Inc. | Immunogenic minicells and methods of use |
| US20030194798A1 (en) | 2001-05-24 | 2003-10-16 | Surber Mark W. | Minicell compositions and methods |
| US20030207833A1 (en) * | 2002-02-25 | 2003-11-06 | Neil Berkley | Pharmaceutical compositions with minicells |
| US20030224369A1 (en) * | 2002-02-25 | 2003-12-04 | Surber Mark W. | Reverse screening and target identification with minicells |
| US20030224444A1 (en) * | 2002-02-25 | 2003-12-04 | Sabbadini Roger A. | Antibodies to native conformations of membrane proteins |
| US20050260585A1 (en) * | 2002-03-19 | 2005-11-24 | Cedric Szpirer | Poison/antidote genetic systems for the selection of genetically modified eucaryote cells or organisms |
| US20040005700A1 (en) * | 2002-05-28 | 2004-01-08 | Surber Mark W. | Poroplasts |
| US9309518B2 (en) | 2002-09-03 | 2016-04-12 | Universite Libre De Bruxelles | Reversible, parallel and multitask cloning method and kit |
| AU2003260200A1 (en) * | 2002-09-03 | 2004-03-29 | Universite Libre De Bruxelles | Reversible, parallel and multitask cloning method and kit |
| GB0327056D0 (en) | 2003-11-20 | 2003-12-24 | Cobra Biolog Ltd | Plasmid maintenance |
| US20060002956A1 (en) * | 2004-04-05 | 2006-01-05 | Surber Mark W | Minicells as vaccines |
| CA2577306A1 (en) | 2004-08-13 | 2006-02-16 | The Trustees Of The University Of Pennsylvania | Methods for constructing antibiotic resistance free vaccines |
| TWI311152B (en) * | 2004-09-17 | 2009-06-21 | Boehringer Ingelheim Rcv Gmbh & Co K | Host-vector system for antibiotic-free cole1 plasmid propagation |
| CN1912127B (zh) * | 2005-08-08 | 2011-05-25 | 百瑞全球有限公司 | 一种大肠杆菌表达载体及其应用 |
| EP2333091B1 (en) | 2007-05-29 | 2017-06-21 | Nature Technology Corporation | Vectors and methods for genetic immunization |
| US20120135033A1 (en) * | 2008-05-19 | 2012-05-31 | Anu Wallecha | Multiple delivery system for heterologous antigens |
| EP2853269B1 (en) | 2008-05-19 | 2019-05-01 | Advaxis, Inc. | Dual delivery system for heterologous antigens comprising a recombinant Listeria strain attenuated by mutation of dal/dat and deletion of ActA comprising a nucleic acid molecule encoding an listeriolysin O - prostate specific anigen fusion protein |
| US9017660B2 (en) | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| US10016617B2 (en) | 2009-11-11 | 2018-07-10 | The Trustees Of The University Of Pennsylvania | Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers |
| EP2498808A4 (en) * | 2009-11-11 | 2014-01-08 | Advaxis | COMPOSITIONS AND METHOD FOR PREVENTING FLUID MUTATIONS IN THE TREATMENT OF TUMORS WITH HER2 / NEW OVEREXPRESSION |
| CN103282048B (zh) | 2010-10-01 | 2017-05-17 | 宾夕法尼亚大学理事会 | 李斯特菌疫苗载体用于在寄生虫感染的个体中扭转免疫无应答的用途 |
| EP3527222B1 (en) | 2011-02-15 | 2021-04-07 | Vaxiion Therapeutics, LLC | Therapeutic compositions and methods for antibody and fc-containing targeting molecule-based targeted delivery of bioactive molecules by bacterial minicells |
| CA2829960A1 (en) | 2011-03-11 | 2012-09-20 | John Rothman | Listeria-based adjuvants |
| KR20140134695A (ko) | 2012-03-12 | 2014-11-24 | 어드박시스, 인크. | 리스테리아 백신 치료 후 억제 세포 기능 저해 |
| AU2013309488A1 (en) | 2012-08-29 | 2015-03-05 | Nature Technology Corporation | DNA plasmids with improved expression |
| WO2014077863A1 (en) | 2012-11-19 | 2014-05-22 | Nature Technology Corporation | Replicative minicircle vectors with improved expression |
| BR112016003533B1 (pt) | 2013-08-19 | 2021-11-03 | Syngulon Sa | Célula microbiana geneticamente modificada e método para controlar o crescimento de uma segunda célula microbiana em um meio de cultura |
| WO2019057774A1 (en) | 2017-09-19 | 2019-03-28 | Deutsches Krebsforschungszentrum | NON-INTEGRATING DNA VECTORS FOR THE GENETIC MODIFICATION OF CELLS |
| FI3456821T4 (fi) | 2017-09-19 | 2024-04-24 | Deutsches Krebsforsch | Ei-integroituvia DNA-vektoreita solujen geneettistä muokkausta varten |
| WO2019121983A1 (en) | 2017-12-19 | 2019-06-27 | Syngulon S.A. | Fermentation process |
| AU2019240068B2 (en) | 2018-03-21 | 2025-03-13 | Aldevron, L.L.C. | Viral and non-viral nanoplasmid vectors with improved production |
| WO2025160245A1 (en) | 2024-01-25 | 2025-07-31 | Aldevron, L.L.C. | Viral and non-viral nanoplasmid vectors with improved production |
| WO2025231315A2 (en) | 2024-05-03 | 2025-11-06 | Aldevron, L.L.C. | Bacterial host strains |
| WO2026076187A1 (en) | 2024-10-03 | 2026-04-09 | Aldevron, L.L.C. | Compositions and methods for microbial production of antibiotic-free closed-ended linear dna |
Family Cites Families (26)
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| US4190495A (en) * | 1976-09-27 | 1980-02-26 | Research Corporation | Modified microorganisms and method of preparing and using same |
| US4968619A (en) * | 1976-09-27 | 1990-11-06 | Research Corporation | Modified microorganisms and method of preparing and using same |
| US5077044A (en) * | 1980-05-19 | 1991-12-31 | The Board Of Trustees Of The Leland Stanford Jr. University | Novel non-reverting shigella live vaccines |
| US4735801A (en) * | 1982-09-07 | 1988-04-05 | Board Of Trustees Of Leland Stanford Jr. University | Novel non-reverting salmonella live vaccines |
| US4837151A (en) * | 1980-05-19 | 1989-06-06 | The Board Of Trustees Of The Leland Stanford Junior University, Stanford University | Live vaccines comprising two mutations and foreign antigen |
| US5210035A (en) * | 1980-05-19 | 1993-05-11 | Board Of Trustees Of Leland Stanford Jr. University | Non-reventing live vaccines |
| US4550081A (en) * | 1980-05-19 | 1985-10-29 | The Board Of Trustees Of The Leland Stanford Jr. University | Non-reverting salmonella |
| US4888170A (en) * | 1981-10-22 | 1989-12-19 | Research Corporation | Vaccines obtained from antigenic gene products of recombinant genes |
| US5702916A (en) * | 1982-09-16 | 1997-12-30 | Gx Biosystems A/S | Biological Containment |
| DK410783D0 (da) * | 1982-09-16 | 1983-09-09 | Benzon A Salfred | Fremgangsmade til stabilisering af plasmider |
| FR2568891B1 (fr) * | 1984-08-09 | 1988-05-27 | Transgene Sa | Procede de preparation d'une souche, notamment de levure, transformee par un vecteur d'expression, qui peut etre cultivee sur un milieu complet sans pression de selection et souche ainsi obtenue |
| DK594084A (da) * | 1984-12-12 | 1986-06-13 | Novo Industri As | Fremgangsmaade til stabilisering af extra-chromosomale elementer i bakterier under dyrkning |
| GB2177097A (en) * | 1985-06-18 | 1987-01-14 | Genencor Inc | Stable maintenance of nucleic acid in recombinant cells |
| DK275685D0 (da) * | 1985-06-18 | 1985-06-18 | Benzon As Alfred | Stabilisering af biologiske systemer |
| IL86583A0 (en) * | 1987-06-04 | 1988-11-15 | Molecular Eng Ass | Vaccine containing a derivative of a microbe and method for the production thereof |
| US5387744A (en) * | 1987-06-04 | 1995-02-07 | Washington University | Avirulent microbes and uses therefor: Salmonella typhi |
| US5294441A (en) * | 1987-06-04 | 1994-03-15 | Washington University | Avirulent microbes and uses therefor: salmonella typhi |
| JPH04501351A (ja) * | 1987-10-07 | 1992-03-12 | ワシントン ユニバーシティ | 細胞の遺伝的集団において所望の組換え遺伝子を維持する方法 |
| IL91525A0 (en) * | 1988-09-06 | 1990-04-29 | Univ Washington | Transgenic plants,pharmaceutical compositions containing the same and methods for the preparation thereof |
| WO1990012086A1 (en) * | 1989-03-31 | 1990-10-18 | Washington University | Bordetella vaccines |
| WO1990011687A1 (en) * | 1989-03-31 | 1990-10-18 | Washington University | VACCINES CONTAINING AVIRULENT phoP-TYPE MICROORGANISMS |
| EP0465561A4 (en) * | 1989-03-31 | 1992-04-08 | Washington University | Avirulent microbes and uses therefor |
| US5399346A (en) * | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| AU6737190A (en) * | 1989-11-03 | 1991-05-31 | Washington University | Cross-protective salmonella vaccines |
| AU9094191A (en) * | 1990-11-21 | 1992-06-25 | Washington University | Recombinant avirulent salmonella antifertility vaccines |
| WO1994024291A2 (en) * | 1993-04-15 | 1994-10-27 | Washington University | Compositions of antigen containing recombinant salmonella, their use in anti-malarial vaccines and method for their preparation |
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1996
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- 1996-10-17 AU AU72088/96A patent/AU7208896A/en not_active Abandoned
- 1996-10-17 WO PCT/CA1996/000693 patent/WO1997014805A2/en not_active Ceased
- 1996-10-17 DE DE69629576T patent/DE69629576T2/de not_active Expired - Fee Related
- 1996-10-17 EP EP96933294A patent/EP0856059B1/en not_active Expired - Lifetime
- 1996-10-17 JP JP9515377A patent/JPH11513562A/ja not_active Ceased
- 1996-10-17 CA CA002232234A patent/CA2232234A1/en not_active Abandoned
- 1996-10-17 AT AT96933294T patent/ATE247713T1/de not_active IP Right Cessation
- 1996-12-24 TW TW085115998A patent/TW514667B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11513562A (ja) | 1999-11-24 |
| CA2232234A1 (en) | 1997-04-24 |
| WO1997014805A3 (en) | 1997-06-12 |
| DE69629576T2 (de) | 2004-06-24 |
| US5922583A (en) | 1999-07-13 |
| ATE247713T1 (de) | 2003-09-15 |
| EP0856059B1 (en) | 2003-08-20 |
| DE69629576D1 (de) | 2003-09-25 |
| WO1997014805A2 (en) | 1997-04-24 |
| EP0856059A1 (en) | 1998-08-05 |
| AU7208896A (en) | 1997-05-07 |
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