TW379228B - Preparation of a stable zinc insulin analog crystals - Google Patents

Preparation of a stable zinc insulin analog crystals Download PDF

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Publication number
TW379228B
TW379228B TW083105905A TW83105905A TW379228B TW 379228 B TW379228 B TW 379228B TW 083105905 A TW083105905 A TW 083105905A TW 83105905 A TW83105905 A TW 83105905A TW 379228 B TW379228 B TW 379228B
Authority
TW
Taiwan
Prior art keywords
human insulin
solution
phenol
patent application
zinc
Prior art date
Application number
TW083105905A
Other languages
English (en)
Chinese (zh)
Inventor
Jeffrey Clayton Baker
Nancy Delores Carter
Bruce Hill Frank
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22990041&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW379228(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of TW379228B publication Critical patent/TW379228B/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
TW083105905A 1994-06-16 1994-06-29 Preparation of a stable zinc insulin analog crystals TW379228B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/260,647 US5504188A (en) 1994-06-16 1994-06-16 Preparation of stable zinc insulin analog crystals

Publications (1)

Publication Number Publication Date
TW379228B true TW379228B (en) 2000-01-11

Family

ID=22990041

Family Applications (1)

Application Number Title Priority Date Filing Date
TW083105905A TW379228B (en) 1994-06-16 1994-06-29 Preparation of a stable zinc insulin analog crystals

Country Status (29)

Country Link
US (1) US5504188A (OSRAM)
EP (1) EP0692489B1 (OSRAM)
JP (1) JP3595607B2 (OSRAM)
KR (1) KR100369951B1 (OSRAM)
CN (1) CN1184234C (OSRAM)
AT (1) ATE233278T1 (OSRAM)
AU (1) AU697794B2 (OSRAM)
BR (1) BR9502798A (OSRAM)
CA (1) CA2151563C (OSRAM)
CO (1) CO4410205A1 (OSRAM)
CZ (1) CZ286066B6 (OSRAM)
DE (1) DE69529708T2 (OSRAM)
DK (1) DK0692489T3 (OSRAM)
ES (1) ES2188637T3 (OSRAM)
FI (1) FI952930L (OSRAM)
HU (1) HUT73495A (OSRAM)
IL (1) IL114152A (OSRAM)
IN (1) IN178919B (OSRAM)
MY (1) MY130551A (OSRAM)
NO (1) NO952334L (OSRAM)
NZ (1) NZ272358A (OSRAM)
PE (1) PE21896A1 (OSRAM)
PL (1) PL180968B1 (OSRAM)
RO (1) RO113529B1 (OSRAM)
RU (1) RU2156257C2 (OSRAM)
SI (1) SI0692489T1 (OSRAM)
TW (1) TW379228B (OSRAM)
YU (1) YU39595A (OSRAM)
ZA (1) ZA954942B (OSRAM)

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WO1998042367A1 (en) * 1997-03-20 1998-10-01 Novo Nordisk A/S Method for preparation of a therapeutic powder through coprecipitation of insulin and absorption enhancer
DE69826705T2 (de) * 1997-11-12 2006-02-23 Alza Corp., Palo Alto Verfahren zur dermalen verabreichung von polypeptiden
RU2205188C2 (ru) 1998-06-30 2003-05-27 Ново Нордиск А/С Затравочные кристаллы для получения пептидов или протеинов
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ATE216258T1 (de) * 1998-10-16 2002-05-15 Novo Nordisk As Insulin präparationen enthaltend methanol zur pulmonaren verabreichung
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CN104892749B (zh) * 2015-06-16 2019-02-05 珠海联邦制药股份有限公司 一种德谷胰岛素结晶的制备方法及应用
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Also Published As

Publication number Publication date
NZ272358A (en) 1996-12-20
HUT73495A (en) 1996-08-28
RU2156257C2 (ru) 2000-09-20
ATE233278T1 (de) 2003-03-15
YU39595A (sh) 1997-08-22
FI952930A0 (fi) 1995-06-14
MY130551A (en) 2007-06-29
DE69529708D1 (de) 2003-04-03
IN178919B (OSRAM) 1997-07-19
AU697794B2 (en) 1998-10-15
BR9502798A (pt) 1996-06-04
ZA954942B (en) 1996-12-17
EP0692489B1 (en) 2003-02-26
EP0692489A1 (en) 1996-01-17
JPH08169899A (ja) 1996-07-02
PE21896A1 (es) 1996-06-15
KR960000922A (ko) 1996-01-25
CN1184234C (zh) 2005-01-12
AU2168195A (en) 1996-01-04
CZ286066B6 (cs) 2000-01-12
IL114152A0 (en) 1995-10-31
DK0692489T3 (da) 2003-03-31
CO4410205A1 (es) 1997-01-09
FI952930A7 (fi) 1995-12-17
PL180968B1 (pl) 2001-05-31
US5504188A (en) 1996-04-02
DE69529708T2 (de) 2003-10-16
IL114152A (en) 1999-12-31
ES2188637T3 (es) 2003-07-01
HU9501715D0 (en) 1995-08-28
RU95110107A (ru) 1997-05-10
CA2151563A1 (en) 1995-12-17
RO113529B1 (ro) 1998-08-28
CN1128271A (zh) 1996-08-07
CZ154195A3 (en) 1996-02-14
SI0692489T1 (en) 2003-06-30
JP3595607B2 (ja) 2004-12-02
PL309099A1 (en) 1995-12-27
KR100369951B1 (ko) 2003-03-28
NO952334L (no) 1995-12-18
NO952334D0 (no) 1995-06-13
CA2151563C (en) 2007-08-07
FI952930L (fi) 1995-12-17

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