TW302369B - - Google Patents
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- TW302369B TW302369B TW083111031A TW83111031A TW302369B TW 302369 B TW302369 B TW 302369B TW 083111031 A TW083111031 A TW 083111031A TW 83111031 A TW83111031 A TW 83111031A TW 302369 B TW302369 B TW 302369B
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- Prior art keywords
- val
- leu
- lys
- sequence
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| JP28050593 | 1993-10-14 |
Publications (1)
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| TW302369B true TW302369B (cg-RX-API-DMAC7.html) | 1997-04-11 |
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| EP (2) | EP1557428A1 (cg-RX-API-DMAC7.html) |
| JP (4) | JP3367581B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR100210308B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN1062908C (cg-RX-API-DMAC7.html) |
| AT (1) | ATE299891T1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2117953C (cg-RX-API-DMAC7.html) |
| DE (1) | DE69434428T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK0657468T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2244955T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT657468E (cg-RX-API-DMAC7.html) |
| TW (1) | TW302369B (cg-RX-API-DMAC7.html) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2751658B1 (fr) * | 1996-07-26 | 1998-10-02 | Pasteur Institut | Utilisation d'une chemokine (sdf-1) ligand pour le recepteur de lestr/fusin/cxcr4 pour prevenir ou traiter l'infection par des virus de type vih |
| EP1012275A1 (en) * | 1997-01-31 | 2000-06-28 | University Of Rochester | Chimeric antibody fusion proteins for the recruitment and stimulation of an antitumor immune response |
| US6852508B1 (en) * | 1997-02-28 | 2005-02-08 | Genetics Institute, Llc | Chemokine with amino-terminal modifications |
| US6100387A (en) | 1997-02-28 | 2000-08-08 | Genetics Institute, Inc. | Chimeric polypeptides containing chemokine domains |
| DE19734161A1 (de) * | 1997-08-07 | 1999-04-01 | Jerini Biotools Gmbh | SDF-1 - Antagonisten |
| MXPA00003885A (es) * | 1997-10-22 | 2004-04-23 | Inst Genetics Llc | Quimiocinas con modificiaciones de la terminacion amino. |
| JP2002506830A (ja) * | 1998-03-13 | 2002-03-05 | ザ ユニバーシティ オブ ブリティッシュ コロンビア | 治療的ケモカイン受容体アンタゴニスト |
| CA2305787A1 (en) * | 2000-05-09 | 2001-11-09 | The University Of British Columbia | Cxcr4 antagonist treatment of hematopoietic cells |
| CA2245224A1 (en) * | 1998-08-14 | 2000-02-14 | Jiang-Hong Giong | Chemokine receptor antagonists and chemotherapeutics |
| DE69932510T2 (de) * | 1998-03-24 | 2007-02-15 | Chugai Seiyaku K.K. | Vaskularisierungsinhibitoren |
| NZ507161A (en) | 1998-03-30 | 2003-12-19 | Northwest Biotherapeutics Inc | Theraupeutic and diagonistic applications based on the role of the CXCR-4 gene in tumorigenesis |
| US7157418B1 (en) | 1998-07-22 | 2007-01-02 | Osprey Pharmaceuticals, Ltd. | Methods and compositions for treating secondary tissue damage and other inflammatory conditions and disorders |
| US20030215421A1 (en) * | 1999-07-21 | 2003-11-20 | Mcdonald John R. | Methods and compositions for treating secondary tissue damage and other inflammatory conditions and disorders |
| AU5241099A (en) * | 1998-07-31 | 2000-02-21 | Trustees Of Columbia University In The City Of New York, The | Use of inhibitors of the activation of cxcr4 receptor by sdf-1 in treating rheumatoid arthritis |
| WO2000059941A1 (en) | 1999-04-08 | 2000-10-12 | The General Hospital Corporation | Purposeful movement of human migratory cells away from an agent source |
| US6949243B1 (en) * | 1999-11-24 | 2005-09-27 | Schering Corporation | Methods of inhibiting metastasis |
| CA2335109A1 (en) * | 2000-04-12 | 2001-10-12 | Chemokine Therapeutics Corporation | Cxcr4 agonist treatment of hematopoietic cells |
| US7378098B2 (en) * | 2000-04-12 | 2008-05-27 | The University Of British Columbia | CXC chemokine receptor 4 agonist peptides |
| US7368425B2 (en) * | 2006-03-24 | 2008-05-06 | Chemokine Therapeutics Corp. | Cyclic peptides for modulating growth of neo-vessels and their use in therapeutic angiogenesis |
| US20050059584A1 (en) * | 2002-08-16 | 2005-03-17 | Ahmed Merzouk | Novel chemokine mimetics synthesis and their use |
| DE10027383A1 (de) * | 2000-06-02 | 2001-12-20 | Rhein Biotech Proz & Prod Gmbh | Nukleinsäure-Molekül umfassend eine für ein Chemokin, einen Neuropeptid-Präkursor oder mindestens ein Neuropeptid kodierende Nukleinsäuresequenz |
| WO2002036078A2 (en) * | 2000-11-05 | 2002-05-10 | University Of Florida | Targeting pluripotent stem cells to tissues |
| JP2004155010A (ja) | 2002-11-06 | 2004-06-03 | Sony Corp | 可逆性多色記録媒体、及びこれを用いた記録方法 |
| JP2004074583A (ja) | 2002-08-19 | 2004-03-11 | Sony Corp | 可逆性多色記録媒体、及びこれを用いた記録方法 |
| TR201907874T4 (tr) * | 2004-09-23 | 2019-06-21 | Arc Medical Devices Inc | Düşük sülfat fukanlar kullanarak fibröz yapışmaları ya da inflamatuar hastalıkları inhibe etmeye yönelik farmasötik kompozisyonlar ve yöntemler. |
| AU2005287855B2 (en) * | 2004-09-24 | 2011-06-16 | Mesoblast, Inc. | Method of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC) |
| US9789171B2 (en) | 2004-11-05 | 2017-10-17 | The General Hospital Corporation | Anti-fugetactic agents for the treatment of ovarian cancer |
| US20060264365A1 (en) * | 2005-05-18 | 2006-11-23 | Hung Li | Treatment of brain tissue damage |
| WO2007048846A1 (de) * | 2005-10-27 | 2007-05-03 | Neuraxo Biopharmaceuticals Gmbh | Verwendung von eisen chelatisierenden verbindungen, zyklisches adenosinmonophosphat erhöhende verbindungen oder kombinationen davon zur behandlung von axonalen läsionen im zns |
| KR20080060226A (ko) * | 2005-10-31 | 2008-07-01 | 라보라토리스 세로노 에스.에이. | 신경 질환의 치료 및/또는 예방을 위한 ｓｄｆ-1의 용도 |
| CN100432106C (zh) * | 2006-06-02 | 2008-11-12 | 广东省微生物研究所 | 一种附着法保藏抗菌肽的方法 |
| WO2008003780A2 (en) * | 2006-07-07 | 2008-01-10 | TRÖSCHER, Herbert | Use of proteins of the sdf-1-family for improvement of axonal plasticity or for axonal regeneration following lesions |
| HUE033630T2 (en) | 2006-10-02 | 2017-12-28 | Squibb & Sons Llc | CXCR4 binding human antibodies and their use |
| US7696309B2 (en) * | 2006-10-23 | 2010-04-13 | The Brigham And Women's Hospital, Inc. | Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
| US20110044945A1 (en) * | 2007-02-08 | 2011-02-24 | Rappaport Family Institute For Research In The Medical Sciences | Agents for the treatment of multiple sclerosis and methods of using same |
| KR100767841B1 (ko) | 2007-03-30 | 2007-10-18 | 주식회사 욱성 | 3중층 구조의 경편직물로 구성한 타이어체인 |
| EP2164508B1 (en) | 2007-06-04 | 2014-01-08 | Rappaport Family Institute for Research in the Medical Sciences | Agents for the treatment of inflammatory diseases and methods of using same |
| US9486497B2 (en) | 2007-12-10 | 2016-11-08 | The University Of Queensland | Treatment of immunocompromised conditions |
| CN101229184B (zh) * | 2008-01-17 | 2010-08-11 | 周锡漳 | 一种脱氧核糖核酸降解片段复合物及其制备药物的应用 |
| US9308277B2 (en) | 2010-02-25 | 2016-04-12 | Mesoblast International Sàrl | Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
| EP2616085A4 (en) * | 2010-09-15 | 2015-04-01 | Cleveland Clinic Foundation | COMPOSITIONS AND METHOD FOR PROMOTING MUSCULO-SKELETAL REPAIR |
| AU2012268078B2 (en) | 2011-06-07 | 2017-06-01 | Mesoblast International Sarl | Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived Factor-1 |
| RS58102B1 (sr) | 2011-11-09 | 2019-02-28 | Bristol Myers Squibb Co | Lečenje hematoloških maligniteta sa anti-cxcr4 antitelom |
| US9908923B2 (en) | 2014-06-11 | 2018-03-06 | The Medical College Of Wisconsin, Inc. | Monomeric CXCL121 peptide and methods of use thereof |
| EP3613435A1 (en) | 2015-01-28 | 2020-02-26 | Universite De Bordeaux | Chemokine receptor cxcr4 inhibitors for treating and/or preventing chronic obstructive pulmonary disease |
| WO2016191811A1 (en) | 2015-06-03 | 2016-12-08 | The University Of Queensland | Mobilizing agents and uses therefor |
| US20190100729A1 (en) | 2017-10-03 | 2019-04-04 | Wallkill BioPharma, Inc. | Treating diabetes with genetically modified beta cells |
| KR102381876B1 (ko) * | 2021-10-27 | 2022-04-01 | 홍천석 | 전선터미널 압착시스템 |
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| JP2879303B2 (ja) * | 1993-01-14 | 1999-04-05 | 佑 本庶 | ｃＤＮＡライブラリーの作製方法、および新規なポリペプチドとそれをコードするＤＮＡ |
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- 1994-10-13 DE DE69434428T patent/DE69434428T2/de not_active Expired - Lifetime
- 1994-10-14 US US08/323,084 patent/US5563048A/en not_active Expired - Lifetime
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- 1994-11-24 TW TW083111031A patent/TW302369B/zh not_active IP Right Cessation
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1996
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2000
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2007
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Also Published As
| Publication number | Publication date |
|---|---|
| DE69434428D1 (de) | 2005-08-25 |
| JP3367581B2 (ja) | 2003-01-14 |
| CN1062908C (zh) | 2001-03-07 |
| JP2001017191A (ja) | 2001-01-23 |
| JP2005336198A (ja) | 2005-12-08 |
| EP0657468A1 (en) | 1995-06-14 |
| US5756084A (en) | 1998-05-26 |
| US5563048A (en) | 1996-10-08 |
| JPH07188294A (ja) | 1995-07-25 |
| JP3705732B2 (ja) | 2005-10-12 |
| DK0657468T3 (da) | 2005-08-08 |
| KR950011618A (ko) | 1995-05-15 |
| EP0657468B1 (en) | 2005-07-20 |
| PT657468E (pt) | 2005-10-31 |
| CA2117953C (en) | 2001-12-11 |
| ATE299891T1 (de) | 2005-08-15 |
| CA2117953A1 (en) | 1995-04-15 |
| JP2007291132A (ja) | 2007-11-08 |
| CN1110323A (zh) | 1995-10-18 |
| KR100210308B1 (ko) | 1999-07-15 |
| ES2244955T3 (es) | 2005-12-16 |
| DE69434428T2 (de) | 2006-05-24 |
| EP1557428A1 (en) | 2005-07-27 |
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