TW294651B - - Google Patents
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- Publication number
- TW294651B TW294651B TW083100416A TW83100416A TW294651B TW 294651 B TW294651 B TW 294651B TW 083100416 A TW083100416 A TW 083100416A TW 83100416 A TW83100416 A TW 83100416A TW 294651 B TW294651 B TW 294651B
- Authority
- TW
- Taiwan
- Prior art keywords
- solvent
- item
- patent application
- reaction
- added
- Prior art date
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- 239000002904 solvent Substances 0.000 claims description 21
- 238000000034 method Methods 0.000 claims description 19
- 239000000376 reactant Substances 0.000 claims description 12
- 159000000000 sodium salts Chemical class 0.000 claims description 12
- 239000011541 reaction mixture Substances 0.000 claims description 7
- -1 2,2-diaminovinyl cyanamide Chemical compound 0.000 claims description 6
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 claims description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 4
- 150000001408 amides Chemical class 0.000 claims description 4
- 239000003960 organic solvent Substances 0.000 claims description 4
- 229910052708 sodium Inorganic materials 0.000 claims description 4
- 239000011734 sodium Substances 0.000 claims description 4
- AVQQQNCBBIEMEU-UHFFFAOYSA-N 1,1,3,3-tetramethylurea Chemical compound CN(C)C(=O)N(C)C AVQQQNCBBIEMEU-UHFFFAOYSA-N 0.000 claims description 3
- 125000000217 alkyl group Chemical group 0.000 claims description 3
- 238000010992 reflux Methods 0.000 claims description 3
- 150000001412 amines Chemical class 0.000 claims description 2
- 239000007810 chemical reaction solvent Substances 0.000 claims description 2
- ATHHXGZTWNVVOU-UHFFFAOYSA-N N-methylformamide Chemical compound CNC=O ATHHXGZTWNVVOU-UHFFFAOYSA-N 0.000 claims 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 1
- LZJHACNNMBYMSO-UHFFFAOYSA-N 1,1-dimethyl-3-propylurea Chemical compound CCCNC(=O)N(C)C LZJHACNNMBYMSO-UHFFFAOYSA-N 0.000 claims 1
- HYTCSCBDAFJMIP-UHFFFAOYSA-N 3-ethyl-1,1-dimethylurea Chemical compound CCNC(=O)N(C)C HYTCSCBDAFJMIP-UHFFFAOYSA-N 0.000 claims 1
- ZMGMDXCADSRNCX-UHFFFAOYSA-N 5,6-dihydroxy-1,3-diazepan-2-one Chemical compound OC1CNC(=O)NCC1O ZMGMDXCADSRNCX-UHFFFAOYSA-N 0.000 claims 1
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 claims 1
- 125000003158 alcohol group Chemical group 0.000 claims 1
- 235000021028 berry Nutrition 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 abstract description 5
- 102000003680 Leukotriene B4 receptors Human genes 0.000 abstract 2
- 108090000093 Leukotriene B4 receptors Proteins 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 230000008485 antagonism Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- BTANRVKWQNVYAZ-UHFFFAOYSA-N butan-2-ol Chemical compound CCC(C)O BTANRVKWQNVYAZ-UHFFFAOYSA-N 0.000 description 36
- 239000000203 mixture Substances 0.000 description 11
- CUONGYYJJVDODC-UHFFFAOYSA-N malononitrile Chemical compound N#CCC#N CUONGYYJJVDODC-UHFFFAOYSA-N 0.000 description 9
- 239000007787 solid Substances 0.000 description 9
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 6
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 6
- 239000002002 slurry Substances 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 3
- 235000013877 carbamide Nutrition 0.000 description 3
- BXWINLIXNNKIRR-UHFFFAOYSA-N sodium azane Chemical compound N.N.[Na+] BXWINLIXNNKIRR-UHFFFAOYSA-N 0.000 description 3
- IXBPPZBJIFNGJJ-UHFFFAOYSA-N sodium;cyanoiminomethylideneazanide Chemical compound [Na+].N#C[N-]C#N IXBPPZBJIFNGJJ-UHFFFAOYSA-N 0.000 description 3
- 239000012258 stirred mixture Substances 0.000 description 3
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 239000004202 carbamide Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- ICRYITQFENSSDB-UHFFFAOYSA-N 2-chloropyrimidine-4,5,6-triamine Chemical compound NC1=NC(Cl)=NC(N)=C1N ICRYITQFENSSDB-UHFFFAOYSA-N 0.000 description 1
- QTANTQQOYSUMLC-UHFFFAOYSA-O Ethidium cation Chemical compound C12=CC(N)=CC=C2C2=CC=C(N)C=C2[N+](CC)=C1C1=CC=CC=C1 QTANTQQOYSUMLC-UHFFFAOYSA-O 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- NKGQVYNEOKALPI-UHFFFAOYSA-N N.N.[K+] Chemical compound N.N.[K+] NKGQVYNEOKALPI-UHFFFAOYSA-N 0.000 description 1
- JSKQRADCWGNYQD-UHFFFAOYSA-N N.O.[Na] Chemical compound N.O.[Na] JSKQRADCWGNYQD-UHFFFAOYSA-N 0.000 description 1
- 229910052771 Terbium Inorganic materials 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- JWEKFMCYIRVOQZ-UHFFFAOYSA-N cyanamide;sodium Chemical compound [Na].NC#N JWEKFMCYIRVOQZ-UHFFFAOYSA-N 0.000 description 1
- 150000003950 cyclic amides Chemical class 0.000 description 1
- QGBSISYHAICWAH-UHFFFAOYSA-N dicyandiamide Chemical compound NC(N)=NC#N QGBSISYHAICWAH-UHFFFAOYSA-N 0.000 description 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
- BDUPRNVPXOHWIL-UHFFFAOYSA-N dimethyl sulfite Chemical compound COS(=O)OC BDUPRNVPXOHWIL-UHFFFAOYSA-N 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 description 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 description 1
- 238000002329 infrared spectrum Methods 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- AXRRPFRZKHRKIZ-UHFFFAOYSA-N lithium dicyanoazanide Chemical compound [Li+].N#C[N-]C#N AXRRPFRZKHRKIZ-UHFFFAOYSA-N 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000003801 milling Methods 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- CSNFMBGHUOSBFU-UHFFFAOYSA-N pyrimidine-2,4,5-triamine Chemical class NC1=NC=C(N)C(N)=N1 CSNFMBGHUOSBFU-UHFFFAOYSA-N 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- ODZPKZBBUMBTMG-UHFFFAOYSA-N sodium amide Chemical compound [NH2-].[Na+] ODZPKZBBUMBTMG-UHFFFAOYSA-N 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- HXJUTPCZVOIRIF-UHFFFAOYSA-N sulfolane Chemical compound O=S1(=O)CCCC1 HXJUTPCZVOIRIF-UHFFFAOYSA-N 0.000 description 1
- GZCRRIHWUXGPOV-UHFFFAOYSA-N terbium atom Chemical compound [Tb] GZCRRIHWUXGPOV-UHFFFAOYSA-N 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Lubricants (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/987,856 US5455274A (en) | 1992-12-09 | 1992-12-09 | Hydroxyamidine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW294651B true TW294651B (enExample) | 1997-01-01 |
Family
ID=25533631
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW082110864A TW267999B (enExample) | 1992-12-09 | 1993-12-22 | |
| TW083100416A TW294651B (enExample) | 1992-12-09 | 1994-01-19 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW082110864A TW267999B (enExample) | 1992-12-09 | 1993-12-22 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5455274A (enExample) |
| EP (1) | EP0601977B1 (enExample) |
| JP (1) | JPH06263710A (enExample) |
| KR (1) | KR940014313A (enExample) |
| AT (1) | ATE148103T1 (enExample) |
| AU (1) | AU671683B2 (enExample) |
| CA (1) | CA2110838A1 (enExample) |
| DE (1) | DE69307669T2 (enExample) |
| DK (1) | DK0601977T3 (enExample) |
| ES (1) | ES2096265T3 (enExample) |
| FI (1) | FI935452A7 (enExample) |
| GR (1) | GR3022367T3 (enExample) |
| HU (1) | HUT65778A (enExample) |
| IL (1) | IL107842A (enExample) |
| NO (2) | NO180300C (enExample) |
| NZ (1) | NZ250379A (enExample) |
| PH (1) | PH29931A (enExample) |
| TW (2) | TW267999B (enExample) |
| ZA (1) | ZA939193B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE222100T1 (de) * | 1993-10-21 | 2002-08-15 | Searle & Co | Amidino-derivate nützlich als no synthase-hemmer |
| DE4424713A1 (de) * | 1994-07-13 | 1996-01-18 | Boehringer Ingelheim Kg | Substituierte Benzamidine, ihre Herstellung und Verwendung als Arnzneistoffe |
| JP2770769B2 (ja) * | 1995-02-16 | 1998-07-02 | 日本メクトロン株式会社 | ビスアミドキシム化合物、その製造法およびそれを含有する含フッ素エラストマー組成物 |
| ID24720A (id) * | 1997-12-12 | 2000-08-03 | Novartis Ag | Senyawa amidino tersubstitusi dalam perawatan penyakit gangguan paru-paru kronis |
| WO2000027199A1 (en) * | 1998-11-12 | 2000-05-18 | Eli Lilly And Company | Aminobenzisoxazole compounds and libraries thereof |
| US7262223B2 (en) | 2004-01-23 | 2007-08-28 | Neurochem (International) Limited | Amidine derivatives for treating amyloidosis |
| EA009902B1 (ru) | 2004-02-13 | 2008-04-28 | УОРНЕР-ЛАМБЕРТ КОМПАНИ Эл-Эл-Си | Модуляторы рецепторов андрогенов |
| JP2007532621A (ja) | 2004-04-13 | 2007-11-15 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | アンドロゲンモジュレータ |
| BRPI0509980A (pt) | 2004-04-22 | 2007-10-16 | Warner Lambert Co | moduladores de androgênio |
| US8338648B2 (en) * | 2004-06-12 | 2012-12-25 | Signum Biosciences, Inc. | Topical compositions and methods for epithelial-related conditions |
| JP4657297B2 (ja) * | 2004-07-05 | 2011-03-23 | ドン ファ ファーマシューティカル カンパニー リミテッド | アレルギー性炎症疾患の予防及び治療用組成物 |
| MXPA06015169A (es) | 2004-07-08 | 2007-08-21 | Warner Lambert Co | Moduladores de androgenos. |
| KR20060017929A (ko) * | 2004-08-04 | 2006-02-28 | 동화약품공업주식회사 | 티아졸 유도체가 치환된 신규한 벤즈아미딘 유도체, 그의제조방법 및 이를 유효성분으로 하는 약학 조성물 |
| TW200724139A (en) | 2005-05-05 | 2007-07-01 | Warner Lambert Co | Androgen modulators |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5922697B2 (ja) * | 1976-01-13 | 1984-05-28 | エーザイ株式会社 | ビス−（メタ−アミジノフエノキシ）−化合物 |
| NL7908922A (nl) * | 1979-12-12 | 1981-07-16 | Akzo Nv | Carboximidamide derivaten. |
| US4324794A (en) * | 1980-08-26 | 1982-04-13 | Research Triangle Institute | Inhibition of respiratory syncytial virus-induced cell fusion by amidino compounds |
| US4661505A (en) * | 1982-11-03 | 1987-04-28 | Eli Lilly And Company | Leukotriene antagonists |
| US4717736A (en) * | 1984-01-23 | 1988-01-05 | Merck Frosst Canada, Inc. | Antagonists of slow reacting substances of anaphylaxis |
| CA1243322A (en) * | 1984-01-23 | 1988-10-18 | Joshua Rokach | Antagonists of slow reacting substances of anaphylaxis |
| DE3830054A1 (de) * | 1988-09-03 | 1990-03-15 | Boehringer Mannheim Gmbh | Phenylamide - verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
| US4933347A (en) * | 1988-10-25 | 1990-06-12 | University Of North Carolina At Chapel Hill | Diamidines and bis(imidazolines) for the treatment of and prophylaxis against pneumocystis carinii pneumonia |
| US4963589A (en) * | 1988-10-25 | 1990-10-16 | The University Of North Carolina At Chapel Hill | Methods for treating Giardia lamblia |
| US5162361A (en) * | 1990-04-10 | 1992-11-10 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Method of treating diseases associated with elevated levels of interleukin 1 |
| US5124350A (en) * | 1990-06-28 | 1992-06-23 | G. D. Searle & Co. | Leukotriene b4 antagonists |
| PL173781B1 (pl) * | 1992-02-05 | 1998-04-30 | Boehringer Ingelheim Kg | Sposób wytwarzania nowych pochodnych amidyny |
-
1992
- 1992-12-09 US US07/987,856 patent/US5455274A/en not_active Expired - Fee Related
-
1993
- 1993-11-24 PH PH47320A patent/PH29931A/en unknown
- 1993-11-26 JP JP5296853A patent/JPH06263710A/ja active Pending
- 1993-11-30 AT AT93810841T patent/ATE148103T1/de not_active IP Right Cessation
- 1993-11-30 DE DE69307669T patent/DE69307669T2/de not_active Expired - Fee Related
- 1993-11-30 DK DK93810841.2T patent/DK0601977T3/da active
- 1993-11-30 ES ES93810841T patent/ES2096265T3/es not_active Expired - Lifetime
- 1993-11-30 EP EP93810841A patent/EP0601977B1/en not_active Expired - Lifetime
- 1993-12-02 IL IL10784293A patent/IL107842A/en not_active IP Right Cessation
- 1993-12-03 AU AU52180/93A patent/AU671683B2/en not_active Ceased
- 1993-12-03 FI FI935452A patent/FI935452A7/fi unknown
- 1993-12-07 CA CA002110838A patent/CA2110838A1/en not_active Abandoned
- 1993-12-07 NZ NZ250379A patent/NZ250379A/en unknown
- 1993-12-08 ZA ZA939193A patent/ZA939193B/xx unknown
- 1993-12-08 NO NO934483A patent/NO180300C/no unknown
- 1993-12-08 NO NO934483D patent/NO934483D0/no unknown
- 1993-12-08 KR KR1019930026826A patent/KR940014313A/ko not_active Withdrawn
- 1993-12-08 HU HU9303501A patent/HUT65778A/hu unknown
- 1993-12-22 TW TW082110864A patent/TW267999B/zh active
-
1994
- 1994-01-19 TW TW083100416A patent/TW294651B/zh not_active IP Right Cessation
-
1997
- 1997-01-23 GR GR970400016T patent/GR3022367T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2096265T3 (es) | 1997-03-01 |
| NO934483L (no) | 1994-06-10 |
| DE69307669T2 (de) | 1997-11-13 |
| ATE148103T1 (de) | 1997-02-15 |
| NZ250379A (en) | 1995-12-21 |
| CA2110838A1 (en) | 1994-06-10 |
| EP0601977B1 (en) | 1997-01-22 |
| EP0601977A1 (en) | 1994-06-15 |
| ZA939193B (en) | 1994-06-09 |
| PH29931A (en) | 1996-09-16 |
| IL107842A0 (en) | 1994-04-12 |
| NO934483D0 (no) | 1993-12-08 |
| TW267999B (enExample) | 1996-01-11 |
| KR940014313A (ko) | 1994-07-18 |
| AU5218093A (en) | 1994-06-23 |
| NO180300B (no) | 1996-12-16 |
| JPH06263710A (ja) | 1994-09-20 |
| FI935452A7 (fi) | 1994-06-10 |
| FI935452A0 (fi) | 1993-12-03 |
| GR3022367T3 (en) | 1997-04-30 |
| DK0601977T3 (da) | 1997-02-10 |
| HUT65778A (en) | 1994-07-28 |
| US5455274A (en) | 1995-10-03 |
| NO180300C (no) | 1997-03-26 |
| DE69307669D1 (de) | 1997-03-06 |
| AU671683B2 (en) | 1996-09-05 |
| HU9303501D0 (en) | 1994-04-28 |
| IL107842A (en) | 1998-08-16 |
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