TW201546284A - 動物模式及治療分子 - Google Patents
動物模式及治療分子 Download PDFInfo
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| CA2846319A1 (en) | 2011-09-19 | 2013-03-28 | Kymab Limited | Antibodies, variable domains & chains tailored for human use |
| EP2761008A1 (en) | 2011-09-26 | 2014-08-06 | Kymab Limited | Chimaeric surrogate light chains (slc) comprising human vpreb |
| US9253965B2 (en) | 2012-03-28 | 2016-02-09 | Kymab Limited | Animal models and therapeutic molecules |
| US10251377B2 (en) | 2012-03-28 | 2019-04-09 | Kymab Limited | Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies |
| GB2502127A (en) | 2012-05-17 | 2013-11-20 | Kymab Ltd | Multivalent antibodies and in vivo methods for their production |
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| US9783593B2 (en) | 2013-05-02 | 2017-10-10 | Kymab Limited | Antibodies, variable domains and chains tailored for human use |
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| WO2017214089A1 (en) * | 2016-06-06 | 2017-12-14 | Regeneron Pharmaceuticals, Inc. | Non-human animals expressing antibodies with human lambda light chains |
| PL3766343T3 (pl) * | 2016-11-04 | 2022-09-26 | Regeneron Pharmaceuticals, Inc. | Zwierzęta inne niż człowiek posiadające zmodyfikowany sposobami inżynierii locus łańcucha lekkiego lambda immunoglobuliny |
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2014
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- 2014-10-01 TW TW103134343A patent/TW201546284A/zh unknown
- 2014-10-01 DE DE112014004537.3T patent/DE112014004537T5/de not_active Withdrawn
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI827567B (zh) * | 2017-12-05 | 2024-01-01 | 美商再生元醫藥公司 | 具有經改造免疫球蛋白λ輕鏈的非人類動物及其用途 |
| US12356967B2 (en) | 2017-12-05 | 2025-07-15 | Regeneron Pharmaceuticals, Inc. | Immunoglobulin lambda light chain and uses thereof |
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| NL2015773A (en) | 2016-09-22 |
| ES2993142T3 (en) | 2024-12-23 |
| ES2859373T3 (es) | 2021-10-01 |
| JP2020036618A (ja) | 2020-03-12 |
| US10966412B2 (en) | 2021-04-06 |
| US20170135327A1 (en) | 2017-05-18 |
| NL2013554A (en) | 2015-04-07 |
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| US20210204530A1 (en) | 2021-07-08 |
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| AU2014330922A1 (en) | 2016-03-03 |
| JP7133902B2 (ja) | 2022-09-09 |
| JP2021087442A (ja) | 2021-06-10 |
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