TW200936566A - Novel crystalline diphenylazetidinone hydrates, medicaments comprising these compounds and use thereof - Google Patents
Novel crystalline diphenylazetidinone hydrates, medicaments comprising these compounds and use thereof Download PDFInfo
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- TW200936566A TW200936566A TW097143436A TW97143436A TW200936566A TW 200936566 A TW200936566 A TW 200936566A TW 097143436 A TW097143436 A TW 097143436A TW 97143436 A TW97143436 A TW 97143436A TW 200936566 A TW200936566 A TW 200936566A
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- 150000004677 hydrates Chemical class 0.000 claims abstract description 7
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- RXSHXLOMRZJCLB-UHFFFAOYSA-L strontium;diacetate Chemical compound [Sr+2].CC([O-])=O.CC([O-])=O RXSHXLOMRZJCLB-UHFFFAOYSA-L 0.000 description 1
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- 239000004094 surface-active agent Substances 0.000 description 1
- 229940099093 symlin Drugs 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
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- 229950005022 taranabant Drugs 0.000 description 1
- 108010048573 taspoglutide Proteins 0.000 description 1
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- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 description 1
- 208000009056 telangiectasis Diseases 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 125000000437 thiazol-2-yl group Chemical group [H]C1=C([H])N=C(*)S1 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
- 102000004217 thyroid hormone receptors Human genes 0.000 description 1
- 108090000721 thyroid hormone receptors Proteins 0.000 description 1
- 229950004437 tiqueside Drugs 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 229960005371 tolbutamide Drugs 0.000 description 1
- CMSGWTNRGKRWGS-NQIIRXRSSA-N torcetrapib Chemical compound COC(=O)N([C@H]1C[C@@H](CC)N(C2=CC=C(C=C21)C(F)(F)F)C(=O)OCC)CC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1 CMSGWTNRGKRWGS-NQIIRXRSSA-N 0.000 description 1
- 229950004514 torcetrapib Drugs 0.000 description 1
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 description 1
- GXPHKUHSUJUWKP-UHFFFAOYSA-N troglitazone Chemical compound C1CC=2C(C)=C(O)C(C)=C(C)C=2OC1(C)COC(C=C1)=CC=C1CC1SC(=O)NC1=O GXPHKUHSUJUWKP-UHFFFAOYSA-N 0.000 description 1
- 229960001641 troglitazone Drugs 0.000 description 1
- GXPHKUHSUJUWKP-NTKDMRAZSA-N troglitazone Natural products C([C@@]1(OC=2C(C)=C(C(=C(C)C=2CC1)O)C)C)OC(C=C1)=CC=C1C[C@H]1SC(=O)NC1=O GXPHKUHSUJUWKP-NTKDMRAZSA-N 0.000 description 1
- INASOKQDNHHMRE-UHFFFAOYSA-N turofexorate isopropyl Chemical compound C1C(C)(C)C(C2=CC=CC=C2N2)=C2C(C(=O)OC(C)C)=CN1C(=O)C1=CC=C(F)C(F)=C1 INASOKQDNHHMRE-UHFFFAOYSA-N 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 125000005287 vanadyl group Chemical group 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 229960001254 vildagliptin Drugs 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
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- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007054497A DE102007054497B3 (de) | 2007-11-13 | 2007-11-13 | Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung |
Publications (1)
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|---|---|
| TW200936566A true TW200936566A (en) | 2009-09-01 |
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| TW097143436A TW200936566A (en) | 2007-11-13 | 2008-11-11 | Novel crystalline diphenylazetidinone hydrates, medicaments comprising these compounds and use thereof |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8003636B2 (enExample) |
| EP (1) | EP2220040B1 (enExample) |
| JP (1) | JP5401463B2 (enExample) |
| AR (1) | AR069305A1 (enExample) |
| CL (1) | CL2008003358A1 (enExample) |
| DE (2) | DE102007054497B3 (enExample) |
| PA (1) | PA8803701A1 (enExample) |
| PE (1) | PE20091165A1 (enExample) |
| TW (1) | TW200936566A (enExample) |
| UY (1) | UY31469A1 (enExample) |
| WO (1) | WO2009062619A1 (enExample) |
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| US8486926B2 (en) * | 2006-11-17 | 2013-07-16 | Harbor Therapeutics, Inc. | Steroid tetrol solid state forms |
| US20080319221A1 (en) * | 2007-06-22 | 2008-12-25 | Bernd Junker | Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids |
| CN101939009B (zh) * | 2008-02-05 | 2013-07-17 | 哈博生物科学公司 | 药学固体形式 |
| DK2273994T3 (en) | 2008-04-03 | 2016-02-01 | Neurmedix Inc | PHARMACEUTICAL FORMS OF A MEDICINE |
| AU2013362400B2 (en) * | 2012-12-22 | 2016-07-28 | Novo Nordisk A/S | Crystal form of compound used as mineralocorticoid receptor antagonist and preparation method therefor |
| US10080759B2 (en) | 2014-01-22 | 2018-09-25 | Duke University | Methods of treating pruritus |
| WO2015112588A1 (en) | 2014-01-22 | 2015-07-30 | Biomimetix Jv, Llc | Methods of treating skin disorders |
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-
2007
- 2007-11-13 DE DE102007054497A patent/DE102007054497B3/de not_active Expired - Fee Related
- 2007-11-13 DE DE102007063671A patent/DE102007063671A1/de not_active Withdrawn
-
2008
- 2008-11-06 JP JP2010533467A patent/JP5401463B2/ja not_active Expired - Fee Related
- 2008-11-06 EP EP08850642A patent/EP2220040B1/de active Active
- 2008-11-06 WO PCT/EP2008/009323 patent/WO2009062619A1/de not_active Ceased
- 2008-11-11 CL CL2008003358A patent/CL2008003358A1/es unknown
- 2008-11-11 TW TW097143436A patent/TW200936566A/zh unknown
- 2008-11-11 PE PE2008001909A patent/PE20091165A1/es not_active Application Discontinuation
- 2008-11-12 US US12/269,802 patent/US8003636B2/en not_active Expired - Fee Related
- 2008-11-12 PA PA20088803701A patent/PA8803701A1/es unknown
- 2008-11-13 AR ARP080104951A patent/AR069305A1/es unknown
- 2008-11-13 UY UY31469A patent/UY31469A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE102007054497B3 (de) | 2009-07-23 |
| JP5401463B2 (ja) | 2014-01-29 |
| US8003636B2 (en) | 2011-08-23 |
| JP2011503127A (ja) | 2011-01-27 |
| PE20091165A1 (es) | 2009-08-31 |
| AR069305A1 (es) | 2010-01-13 |
| DE102007063671A1 (de) | 2009-06-25 |
| EP2220040A1 (de) | 2010-08-25 |
| WO2009062619A1 (de) | 2009-05-22 |
| PA8803701A1 (es) | 2009-06-23 |
| UY31469A1 (es) | 2009-07-17 |
| CL2008003358A1 (es) | 2009-06-26 |
| EP2220040B1 (de) | 2013-01-16 |
| US20090203578A1 (en) | 2009-08-13 |
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