TW200416036A - Medicinal preparation containing phenylethanoid glycosides extracted from herbaceous plant, cistanche tubulosa (schenk.) wight, process of making the same, and uses of the same - Google Patents
Medicinal preparation containing phenylethanoid glycosides extracted from herbaceous plant, cistanche tubulosa (schenk.) wight, process of making the same, and uses of the same Download PDFInfo
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- TW200416036A TW200416036A TW092103351A TW92103351A TW200416036A TW 200416036 A TW200416036 A TW 200416036A TW 092103351 A TW092103351 A TW 092103351A TW 92103351 A TW92103351 A TW 92103351A TW 200416036 A TW200416036 A TW 200416036A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 90
- 229930182470 glycoside Natural products 0.000 title claims abstract description 54
- 241000336316 Cistanche tubulosa Species 0.000 title claims abstract description 27
- 238000000034 method Methods 0.000 title claims description 10
- 150000002338 glycosides Chemical class 0.000 title abstract description 3
- 241000196324 Embryophyta Species 0.000 title abstract 2
- 230000008569 process Effects 0.000 title description 2
- 239000000203 mixture Substances 0.000 claims abstract description 19
- NJYVDFDTLLZVMG-UHFFFAOYSA-N echinacoside Natural products CC1OC(OC2C(O)C(OCCc3ccc(O)c(O)c3)OC(COC4OC(CO)C(O)C(O)C4O)C2OC(=O)C=Cc5cc(O)cc(O)c5)C(O)C(O)C1O NJYVDFDTLLZVMG-UHFFFAOYSA-N 0.000 claims abstract description 16
- FSBUXLDOLNLABB-ISAKITKMSA-N echinacoside Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](OC(=O)\C=C\C=2C=C(O)C(O)=CC=2)[C@@H](CO[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)O[C@@H](OCCC=2C=C(O)C(O)=CC=2)[C@@H]1O FSBUXLDOLNLABB-ISAKITKMSA-N 0.000 claims abstract description 16
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- 229930185474 acteoside Natural products 0.000 claims abstract description 7
- FBSKJMQYURKNSU-ZLSOWSIRSA-N acteoside Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](OC(=O)\C=C\C=2C=C(O)C(O)=CC=2)[C@@H](CO)O[C@@H](OCCC=2C=C(O)C(O)=CC=2)[C@@H]1O FBSKJMQYURKNSU-ZLSOWSIRSA-N 0.000 claims abstract description 7
- FBSKJMQYURKNSU-UKQWSTALSA-N acteoside I Natural products C[C@@H]1O[C@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)C=Cc4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O FBSKJMQYURKNSU-UKQWSTALSA-N 0.000 claims abstract description 7
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- -1 phenylethanol glycosides Chemical class 0.000 claims description 54
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- FPOYEEKZOOLVJA-WLLRULDYSA-N [(2s,4ar,6r,7r,8s,8ar)-2-(3,4-dihydroxyphenyl)-6-(hydroxymethyl)-8-[(2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-3,4a,6,7,8,8a-hexahydro-2h-pyrano[2,3-b][1,4]dioxin-7-yl] (e)-3-(3,4-dihydroxyphenyl)prop-2-enoate Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1[C@H]2O[C@@H](C=3C=C(O)C(O)=CC=3)CO[C@@H]2O[C@H](CO)[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 FPOYEEKZOOLVJA-WLLRULDYSA-N 0.000 claims description 4
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
- G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
- G01N27/12—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a solid body in dependence upon absorption of a fluid; of a solid body in dependence upon reaction with a fluid, for detecting components in the fluid
- G01N27/125—Composition of the body, e.g. the composition of its sensitive layer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
- G01M3/00—Investigating fluid-tightness of structures
- G01M3/02—Investigating fluid-tightness of structures by using fluid or vacuum
- G01M3/04—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point
- G01M3/16—Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using electric detection means
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- G—PHYSICS
- G08—SIGNALLING
- G08B—SIGNALLING OR CALLING SYSTEMS; ORDER TELEGRAPHS; ALARM SYSTEMS
- G08B21/00—Alarms responsive to a single specified undesired or abnormal condition and not otherwise provided for
- G08B21/02—Alarms for ensuring the safety of persons
- G08B21/12—Alarms for ensuring the safety of persons responsive to undesired emission of substances, e.g. pollution alarms
- G08B21/16—Combustible gas alarms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Biotechnology (AREA)
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- Organic Chemistry (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
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- Pathology (AREA)
- Hospice & Palliative Care (AREA)
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Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW092103351A TW200416036A (en) | 2003-02-18 | 2003-02-18 | Medicinal preparation containing phenylethanoid glycosides extracted from herbaceous plant, cistanche tubulosa (schenk.) wight, process of making the same, and uses of the same |
| US10/618,740 US7087252B2 (en) | 2003-02-18 | 2003-07-15 | Medicinal preparation containing phenylethanoid glycosides extracted from herbaceous plant, Cistanche tubulosa (Schrenk.) Wight, process of making the same, and uses of the same |
| JP2004039317A JP4926376B2 (ja) | 2003-02-18 | 2004-02-17 | 草本植物である、ハマウツボ科の全寄生植物［ｃｉｓｔａｎｃｈｅｔｕｂｕｌｏｓａ（ｓｃｈｅｎｋ．）ｗｉｇｈｔ］から抽出されるフェニルエタノイド配糖体を含む医薬調製物、これの製造方法およびこれの使用 |
| CA002457996A CA2457996C (en) | 2003-02-18 | 2004-02-17 | Medicinal preparation containing phenylethanoid glycosides extracted from herbaceous plant, cistanche tubulosa (schenk.) wight, process of making the same, and uses of the same |
| AU2004200624A AU2004200624B2 (en) | 2003-02-18 | 2004-02-17 | Medicinal preparation containing phenylethanoid glycosides extracted from herbaceous plant, cistanche tubulosa (schenk.) wight, process of making the same, and uses of the same |
| KR1020040010530A KR20040074614A (ko) | 2003-02-18 | 2004-02-18 | 초본식물, 시스탄체 투부로사(스첸크) 위그트로부터추출되는 페닐에타노이드 글리코시드를 함유하는 의약제제, 그것의 제조방법, 및 그것의 사용 |
| US11/452,302 US20060233896A1 (en) | 2003-02-18 | 2006-06-14 | Medicinal preparation containing phenylethanoid glycosides extracted from herbaceous plant, Cistanche tubulosa (Schenk.) Wight, process of making the same, and uses of the same |
| JP2011220805A JP5352655B2 (ja) | 2003-02-18 | 2011-10-05 | 草本植物である、ハマウツボ科の全寄生植物［ｃｉｓｔａｎｃｈｅｔｕｂｕｌｏｓａ（ｓｃｈｅｎｋ．）ｗｉｇｈｔ］から抽出されるフェニルエタノイド配糖体を含む医薬調製物、これの製造方法およびこれの使用 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW092103351A TW200416036A (en) | 2003-02-18 | 2003-02-18 | Medicinal preparation containing phenylethanoid glycosides extracted from herbaceous plant, cistanche tubulosa (schenk.) wight, process of making the same, and uses of the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200416036A true TW200416036A (en) | 2004-09-01 |
| TWI331529B TWI331529B (OSRAM) | 2010-10-11 |
Family
ID=32847870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW092103351A TW200416036A (en) | 2003-02-18 | 2003-02-18 | Medicinal preparation containing phenylethanoid glycosides extracted from herbaceous plant, cistanche tubulosa (schenk.) wight, process of making the same, and uses of the same |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7087252B2 (OSRAM) |
| JP (2) | JP4926376B2 (OSRAM) |
| KR (1) | KR20040074614A (OSRAM) |
| AU (1) | AU2004200624B2 (OSRAM) |
| CA (1) | CA2457996C (OSRAM) |
| TW (1) | TW200416036A (OSRAM) |
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| TWI488630B (zh) * | 2011-12-16 | 2015-06-21 | Sinphar Pharmaceutical Co Ltd | 預防或治療澱粉樣β肽相關疾病或狀況的醫藥組合物 |
| CN105111255A (zh) * | 2015-08-12 | 2015-12-02 | 青海伊纳维康生物科技有限公司 | 一种肉苁蓉中松果菊苷和毛蕊花糖苷的提取分离方法 |
| TWI619721B (zh) * | 2014-04-10 | 2018-04-01 | 杏輝藥品工業股份有限公司 | 異類葉升麻苷衍生物及其製造方法與用途 |
| CN109369739A (zh) * | 2018-11-16 | 2019-02-22 | 山东省药学科学院 | 一种具有脑保护活性的过山蕨植物提取物及其制备方法 |
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| EP1736167B1 (en) * | 2005-06-20 | 2018-03-21 | I.R.B. Istituto Di Ricerche Biotecnologiche S.r.l. | Extracts obtained from cell line cultures from Syringa vulgaris IRB-SV25/B (DMS:16857), their preparation and use |
| JP4965132B2 (ja) * | 2006-01-27 | 2012-07-04 | 森下仁丹株式会社 | 更年期障害改善剤 |
| AR059545A1 (es) * | 2006-02-28 | 2008-04-09 | Bayer Consumer Care Ag | Combinacion de verbacosido y luteolina |
| CN100475189C (zh) * | 2006-10-17 | 2009-04-08 | 王海龙 | 一种化妆品组合物及其制备方法和应用 |
| WO2008093678A1 (ja) * | 2007-01-29 | 2008-08-07 | Oryza Oil & Fat Chemical Co., Ltd. | ヒアルロニダーゼ阻害剤 |
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| JP2008280271A (ja) * | 2007-05-09 | 2008-11-20 | Oriza Yuka Kk | 皮膚光老化予防剤 |
| JP2009196895A (ja) * | 2008-02-19 | 2009-09-03 | Oriza Yuka Kk | チロシナーゼ阻害剤 |
| JP2009196908A (ja) * | 2008-02-20 | 2009-09-03 | Yomeishu Seizo Co Ltd | リパーゼ阻害剤及び飲食品 |
| JP2009263279A (ja) * | 2008-04-25 | 2009-11-12 | Oriza Yuka Kk | エラスターゼ阻害剤 |
| TWI486162B (zh) * | 2010-06-16 | 2015-06-01 | Sinphar Pharmaceutical Co Ltd | 異類葉升麻苷或其醫藥學上可接受之鹽於抑制澱粉樣β肽生成、累積或聚集、以及製備預防或治療澱粉樣β肽相關疾病或狀況的藥物之用途 |
| CN102329346A (zh) * | 2011-05-31 | 2012-01-25 | 苏州派腾生物医药科技有限公司 | 一种从肉苁蓉中提取松果菊苷的方法 |
| CN102304156B (zh) * | 2011-06-24 | 2016-03-16 | 浙江爱诺药业股份有限公司 | 一种苯乙醇苷类成份及其制备方法和用途 |
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| US9339522B2 (en) * | 2013-05-30 | 2016-05-17 | Sinphar Pharmaceutical Co., Ltd. | Method for regulating blood glucose level |
| CN106413730A (zh) | 2014-05-08 | 2017-02-15 | 捷通国际有限公司 | 使用包含肉苁蓉属和银杏属提取物的组合物改善受试者的记忆的方法 |
| KR102195547B1 (ko) * | 2016-01-12 | 2020-12-28 | 신파 티엔리 파머슈티컬 컴퍼니 리미티드 (항저우) | 근육의 보호에서 시스탄케 투불로사 추출물 및 이소악테오사이드의 용도 |
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| CN110812375A (zh) * | 2019-12-12 | 2020-02-21 | 中国海洋大学 | 一种老鼠簕中苯乙醇苷类提取物及其制备方法与作为抗肝损伤药物的应用 |
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| CN115778971B (zh) * | 2023-01-08 | 2025-06-24 | 中国中医科学院中药研究所 | 一种包含肉苁蓉成分的药物组合物及其用途 |
| CN116549466A (zh) * | 2023-06-06 | 2023-08-08 | 上海泰楚生物技术有限公司 | 一种毛蕊花糖苷化合物在制备抗动脉血栓形成的药物中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07223964A (ja) * | 1994-02-01 | 1995-08-22 | Du Pont Merck Pharmaceut Co | ホスホリパーゼａ２阻害剤 |
| JPH0940597A (ja) * | 1994-12-13 | 1997-02-10 | Natl Sci Council | シナモフィリン及びその誘導体とこれらの製造方法及び血小板凝集抑制薬剤、気管弛緩薬剤、酸化防止剤及び血管弛緩薬剤 |
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2003
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- 2003-07-15 US US10/618,740 patent/US7087252B2/en not_active Expired - Lifetime
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- 2004-02-17 CA CA002457996A patent/CA2457996C/en not_active Expired - Lifetime
- 2004-02-17 JP JP2004039317A patent/JP4926376B2/ja not_active Expired - Lifetime
- 2004-02-18 KR KR1020040010530A patent/KR20040074614A/ko not_active Ceased
-
2006
- 2006-06-14 US US11/452,302 patent/US20060233896A1/en not_active Abandoned
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- 2011-10-05 JP JP2011220805A patent/JP5352655B2/ja not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI488630B (zh) * | 2011-12-16 | 2015-06-21 | Sinphar Pharmaceutical Co Ltd | 預防或治療澱粉樣β肽相關疾病或狀況的醫藥組合物 |
| TWI619721B (zh) * | 2014-04-10 | 2018-04-01 | 杏輝藥品工業股份有限公司 | 異類葉升麻苷衍生物及其製造方法與用途 |
| CN105111255A (zh) * | 2015-08-12 | 2015-12-02 | 青海伊纳维康生物科技有限公司 | 一种肉苁蓉中松果菊苷和毛蕊花糖苷的提取分离方法 |
| CN109369739A (zh) * | 2018-11-16 | 2019-02-22 | 山东省药学科学院 | 一种具有脑保护活性的过山蕨植物提取物及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| TWI331529B (OSRAM) | 2010-10-11 |
| JP2004250449A (ja) | 2004-09-09 |
| US20060233896A1 (en) | 2006-10-19 |
| CA2457996A1 (en) | 2004-08-18 |
| US20040162246A1 (en) | 2004-08-19 |
| AU2004200624B2 (en) | 2006-02-16 |
| JP4926376B2 (ja) | 2012-05-09 |
| AU2004200624A1 (en) | 2004-09-02 |
| KR20040074614A (ko) | 2004-08-25 |
| JP2012021022A (ja) | 2012-02-02 |
| JP5352655B2 (ja) | 2013-11-27 |
| US7087252B2 (en) | 2006-08-08 |
| CA2457996C (en) | 2009-08-04 |
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