TR201901496T4 - Wnt/Beta -katenin sinyal yolağı aktivatörleri olarak gamma-diketonları. - Google Patents

Wnt/Beta -katenin sinyal yolağı aktivatörleri olarak gamma-diketonları. Download PDF

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Publication number
TR201901496T4
TR201901496T4 TR2019/01496T TR201901496T TR201901496T4 TR 201901496 T4 TR201901496 T4 TR 201901496T4 TR 2019/01496 T TR2019/01496 T TR 2019/01496T TR 201901496 T TR201901496 T TR 201901496T TR 201901496 T4 TR201901496 T4 TR 201901496T4
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compound
disease
bone
formula
cells
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TR2019/01496T
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Turkish (tr)
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Kc Kumar Sunil
Mark Wallace David
Hood John
Barroga Charlene
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Samumed Llc
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TR2019/01496T 2013-02-22 2014-02-21 Wnt/Beta -katenin sinyal yolağı aktivatörleri olarak gamma-diketonları. TR201901496T4 (tr)

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EP (2) EP3456325A3 (enExample)
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PL2464232T3 (pl) 2009-08-10 2016-04-29 Samumed Llc Indazolowe inhibitory szlaku sygnałowego Wnt i ich zastosowania terapeutyczne
MX340997B (es) 2010-08-18 2016-08-03 Samumed Llc Dicetonas e hidroxicetonas como activadores de la trayectoria de señalizacion de catenina.
SG11201506592SA (en) 2013-02-22 2015-09-29 Samumed Llc Gamma-diketones as wnt/beta -catenin signaling pathway activators
WO2016029021A1 (en) 2014-08-20 2016-02-25 Samumed, Llc Gamma-diketones for treatment and prevention of aging skin and wrinkles
CN104311544A (zh) * 2014-09-22 2015-01-28 湖南华腾制药有限公司 一种苯并恶唑衍生物的制备方法
CN104292179A (zh) * 2014-10-19 2015-01-21 湖南华腾制药有限公司 一种2-氯苯并[d]恶唑-5-甲醛的制备方法
BR112017027227B1 (pt) 2015-06-16 2023-12-12 Eisai R&D Management Co., Ltd Agente anti-câncer
ES2870013T3 (es) 2015-06-23 2021-10-26 Eisai R&D Man Co Ltd Cristal de (6S,9aS)-N-bencil-8-({6-[3-(4-etilpiperazin-1-il)azetidin-1-il]piridin-2-il}metil)-6-(2-fluoro-4-hidroxibencil)-4,7-dioxo-2-(prop-2-en-1-il)hexahidro-2H-pirazino[2,1-c][1,2,4]triazin-1(6H)-carboxamida
KR102539920B1 (ko) 2017-02-08 2023-06-05 에자이 알앤드디 매니지먼트 가부시키가이샤 종양-치료용 약제학적 조성물
US20200197384A1 (en) 2017-05-16 2020-06-25 Eisai R&D Management Co., Ltd. Treatment of hepatocellular carcinoma
CN109678687B (zh) * 2018-12-11 2022-02-11 沾化大荣化工科技有限公司 一种邻羟基苯乙酮类化合物的高效制备方法
US12398126B2 (en) * 2019-06-06 2025-08-26 Fermenta Biotech Limited Process to synthesize 5-(3pyridyl)-2,2′-bithiophene(sensitizer)
CN111632147A (zh) * 2020-06-07 2020-09-08 重庆医科大学 骨细胞Wnt激活剂在制备骨折加速愈合、防治骨不连及不运动或失重骨丢失药物中的应用
EP4173675A1 (en) * 2021-10-26 2023-05-03 Perha Pharmaceuticals Imidazolone derivatives as inhibitors of protein kinases in particular dyrk1a, clk1 and/or clk4
CN116808027B (zh) * 2023-05-30 2025-08-29 重庆医科大学附属第一医院 化合物或其盐在制备抑制wnt7a基因活性的制剂中的应用

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