TR200202048T2 - Sitalopramin preparasyon metodu. - Google Patents
Sitalopramin preparasyon metodu.Info
- Publication number
- TR200202048T2 TR200202048T2 TR2002/02048T TR200202048T TR200202048T2 TR 200202048 T2 TR200202048 T2 TR 200202048T2 TR 2002/02048 T TR2002/02048 T TR 2002/02048T TR 200202048 T TR200202048 T TR 200202048T TR 200202048 T2 TR200202048 T2 TR 200202048T2
- Authority
- TR
- Turkey
- Prior art keywords
- preparation
- citalopramine
- formula
- citalopram
- alkylated
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- WSEQXVZVJXJVFP-HXUWFJFHSA-N (R)-citalopram Chemical compound C1([C@@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-HXUWFJFHSA-N 0.000 abstract 2
- 229960001653 citalopram Drugs 0.000 abstract 2
- -1 5-cyano compound Chemical class 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200000296 | 2000-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200202048T2 true TR200202048T2 (tr) | 2003-01-21 |
Family
ID=8159208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2002/02048T TR200202048T2 (tr) | 2000-02-24 | 2001-02-22 | Sitalopramin preparasyon metodu. |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | US20020004604A1 (enExample) |
| EP (1) | EP1259500A1 (enExample) |
| JP (1) | JP2003524009A (enExample) |
| KR (1) | KR20020080438A (enExample) |
| CN (1) | CN1161350C (enExample) |
| AU (1) | AU2001235357A1 (enExample) |
| BE (1) | BE1012921A6 (enExample) |
| BG (1) | BG107015A (enExample) |
| BR (1) | BR0108947A (enExample) |
| CA (1) | CA2400682A1 (enExample) |
| EA (1) | EA005593B1 (enExample) |
| FR (1) | FR2805813A1 (enExample) |
| GR (1) | GR20010100097A (enExample) |
| HK (1) | HK1054378B (enExample) |
| HR (1) | HRP20020743A2 (enExample) |
| HU (1) | HUP0300078A3 (enExample) |
| IE (1) | IES20010143A2 (enExample) |
| IL (1) | IL151339A0 (enExample) |
| IS (1) | IS6512A (enExample) |
| IT (1) | ITMI20010385A1 (enExample) |
| MX (1) | MXPA02008230A (enExample) |
| NL (1) | NL1017414C1 (enExample) |
| NO (1) | NO20024007L (enExample) |
| PL (1) | PL357178A1 (enExample) |
| SK (1) | SK13662002A3 (enExample) |
| TR (1) | TR200202048T2 (enExample) |
| UA (1) | UA71059C2 (enExample) |
| WO (1) | WO2001062754A1 (enExample) |
| ZA (2) | ZA200206255B (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR022329A1 (es) | 1999-01-29 | 2002-09-04 | Lundbeck & Co As H | Metodo para la preparacion de 5-cianoftalida |
| IL145615A0 (en) * | 1999-04-14 | 2002-06-30 | Lundbeck & Co As H | Method for the preparation of citalopram |
| ITMI991581A1 (it) * | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | Metodo per la preparazione di citalopram |
| HK1043129B (zh) | 1999-10-25 | 2004-10-21 | H‧隆德贝克有限公司 | 西酞普蘭的製備方法 |
| AR026063A1 (es) | 1999-11-01 | 2002-12-26 | Lundbeck & Co As H | Metodo para la preparacion de 5-carboxiftalida. |
| US6310222B1 (en) | 1999-11-01 | 2001-10-30 | Sumika Fine Chemicals Co., Ltd. | Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate |
| NZ519739A (en) | 1999-12-28 | 2004-03-26 | H | Method for the preparation of citalopram |
| PT1246813E (pt) | 1999-12-30 | 2004-02-27 | Lundbeck & Co As H | Metodo para a preparacao de citalopram |
| WO2001051477A1 (en) * | 2000-01-14 | 2001-07-19 | H. Lundbeck A/S | Method for the preparation of 5-cyanophthalide |
| US6433196B1 (en) | 2000-02-17 | 2002-08-13 | Sumika Fine Chemicals Co., Ltd. | Production method of citalopram, intermediate therefor and production method of the intermediate |
| IES20010157A2 (en) | 2000-03-03 | 2002-03-06 | Lundbeck & Co As H | Method for the preparation of citalopram |
| GB0005477D0 (en) | 2000-03-07 | 2000-04-26 | Resolution Chemicals Limited | Process for the preparation of citalopram |
| NL1017500C1 (nl) | 2000-03-13 | 2001-04-26 | Lundbeck & Co As H | Werkwijze voor de bereiding van Citalopram. |
| BR0109364A (pt) | 2000-03-13 | 2002-12-24 | Lundbeck & Co As H | Métodos para fabricação de citalopram através de alquilação escalonada de 5-substituìda 1- (4-fluorofenil) - 1,3- diidroisobenzofuranos e citalopram |
| SK14602002A3 (sk) * | 2000-03-13 | 2003-02-04 | H. Lundbeck A/S | Spôsob výroby citalopramu a medziprodukty |
| IL151488A0 (en) | 2000-03-14 | 2003-04-10 | Lundbeck & Co As H | Method for the preparation of citalopram |
| TR200202168T2 (tr) | 2000-03-16 | 2002-12-23 | H. Lundbeck A/S | 5-Siyano-1-(4-Florofenil)-1,3-Dihidroizobenzofuranların preparasyon metodu |
| AR032455A1 (es) | 2000-05-12 | 2003-11-12 | Lundbeck & Co As H | Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva |
| IL144816A (en) | 2000-08-18 | 2005-09-25 | Lundbeck & Co As H | Method for the preparation of citalopram |
| TR200201166T1 (tr) | 2000-12-22 | 2002-10-21 | H.Lundbecks A/S | Saf sitalopram hazırlanması için yöntem |
| DK1281707T3 (da) * | 2001-08-02 | 2005-05-02 | Infosint Sa | Fremgangsmåde til fremstilling af 5-substituerede isobenzenfuraner |
| WO2004016602A1 (en) * | 2002-08-14 | 2004-02-26 | Natco Pharma Limited | Process for the preparation of high purity citalopram and its pharmaceutically acceptable salts |
| US8539533B2 (en) * | 2003-03-07 | 2013-09-17 | Siemens Enterprise Communications, Inc. | System and method for digital personal video stream manager |
| AU2003223105A1 (en) * | 2003-03-24 | 2004-10-18 | Hetero Drugs Limited | Novel crystalline forms of (s)-citalopram oxalate |
| CN100569765C (zh) | 2003-12-19 | 2009-12-16 | 杭州民生药业集团有限公司 | 西酞普兰中间体晶体碱 |
| JP2006176490A (ja) * | 2004-11-29 | 2006-07-06 | Sumitomo Chemical Co Ltd | ５−フタランカルボニトリル及びシタロプラムの製造方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1526331A (en) * | 1976-01-14 | 1978-09-27 | Kefalas As | Phthalanes |
| UA62985C2 (en) * | 1997-11-10 | 2004-01-15 | Lunnbeck As H | A method for the preparation of citalopram |
| IL145615A0 (en) * | 1999-04-14 | 2002-06-30 | Lundbeck & Co As H | Method for the preparation of citalopram |
| US6310222B1 (en) * | 1999-11-01 | 2001-10-30 | Sumika Fine Chemicals Co., Ltd. | Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate |
| US6433196B1 (en) * | 2000-02-17 | 2002-08-13 | Sumika Fine Chemicals Co., Ltd. | Production method of citalopram, intermediate therefor and production method of the intermediate |
-
2001
- 2001-02-19 IE IE20010143A patent/IES20010143A2/en not_active IP Right Cessation
- 2001-02-21 FR FR0102341A patent/FR2805813A1/fr active Pending
- 2001-02-21 NL NL1017414A patent/NL1017414C1/nl not_active IP Right Cessation
- 2001-02-22 CA CA002400682A patent/CA2400682A1/en not_active Abandoned
- 2001-02-22 WO PCT/DK2001/000122 patent/WO2001062754A1/en not_active Ceased
- 2001-02-22 MX MXPA02008230A patent/MXPA02008230A/es unknown
- 2001-02-22 CN CNB018055192A patent/CN1161350C/zh not_active Expired - Fee Related
- 2001-02-22 TR TR2002/02048T patent/TR200202048T2/xx unknown
- 2001-02-22 HK HK03106541.8A patent/HK1054378B/zh not_active IP Right Cessation
- 2001-02-22 HR HR20020743A patent/HRP20020743A2/hr not_active Application Discontinuation
- 2001-02-22 IL IL15133901A patent/IL151339A0/xx unknown
- 2001-02-22 HU HU0300078A patent/HUP0300078A3/hu unknown
- 2001-02-22 GR GR20010100097A patent/GR20010100097A/el unknown
- 2001-02-22 JP JP2001562536A patent/JP2003524009A/ja active Pending
- 2001-02-22 BR BR0108947-1A patent/BR0108947A/pt not_active IP Right Cessation
- 2001-02-22 AU AU2001235357A patent/AU2001235357A1/en not_active Abandoned
- 2001-02-22 KR KR1020027011113A patent/KR20020080438A/ko not_active Ceased
- 2001-02-22 EP EP01907388A patent/EP1259500A1/en not_active Withdrawn
- 2001-02-22 EA EA200200900A patent/EA005593B1/ru not_active IP Right Cessation
- 2001-02-22 BE BE2001/0118A patent/BE1012921A6/fr not_active IP Right Cessation
- 2001-02-22 UA UA2002086988A patent/UA71059C2/uk unknown
- 2001-02-22 SK SK1366-2002A patent/SK13662002A3/sk unknown
- 2001-02-22 PL PL01357178A patent/PL357178A1/xx not_active Application Discontinuation
- 2001-02-26 IT IT2001MI000385A patent/ITMI20010385A1/it unknown
- 2001-02-26 US US09/794,755 patent/US20020004604A1/en not_active Abandoned
-
2002
- 2002-08-06 ZA ZA200206255A patent/ZA200206255B/en unknown
- 2002-08-20 IS IS6512A patent/IS6512A/is unknown
- 2002-08-20 BG BG107015A patent/BG107015A/bg unknown
- 2002-08-21 ZA ZA200206699A patent/ZA200206699B/xx unknown
- 2002-08-22 NO NO20024007A patent/NO20024007L/no not_active Application Discontinuation
- 2002-08-23 US US10/228,388 patent/US20030083508A1/en not_active Abandoned
- 2002-11-01 US US10/286,407 patent/US20030114692A1/en not_active Abandoned
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