GR20010100097A - Μεθοδος παρασκευης της σιταλοπραμης - Google Patents

Μεθοδος παρασκευης της σιταλοπραμης

Info

Publication number
GR20010100097A
GR20010100097A GR20010100097A GR2001100097A GR20010100097A GR 20010100097 A GR20010100097 A GR 20010100097A GR 20010100097 A GR20010100097 A GR 20010100097A GR 2001100097 A GR2001100097 A GR 2001100097A GR 20010100097 A GR20010100097 A GR 20010100097A
Authority
GR
Greece
Prior art keywords
citalopram
preparation
formula
alkylated
aldehyde
Prior art date
Application number
GR20010100097A
Other languages
Greek (el)
English (en)
Inventor
Hans Petersen
Harold Michael Rock
Original Assignee
H.Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8159208&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR20010100097(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by H.Lundbeck A/S filed Critical H.Lundbeck A/S
Publication of GR20010100097A publication Critical patent/GR20010100097A/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Furan Compounds (AREA)
GR20010100097A 2000-02-24 2001-02-22 Μεθοδος παρασκευης της σιταλοπραμης GR20010100097A (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200000296 2000-02-24

Publications (1)

Publication Number Publication Date
GR20010100097A true GR20010100097A (el) 2001-10-31

Family

ID=8159208

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010100097A GR20010100097A (el) 2000-02-24 2001-02-22 Μεθοδος παρασκευης της σιταλοπραμης

Country Status (29)

Country Link
US (3) US20020004604A1 (enExample)
EP (1) EP1259500A1 (enExample)
JP (1) JP2003524009A (enExample)
KR (1) KR20020080438A (enExample)
CN (1) CN1161350C (enExample)
AU (1) AU2001235357A1 (enExample)
BE (1) BE1012921A6 (enExample)
BG (1) BG107015A (enExample)
BR (1) BR0108947A (enExample)
CA (1) CA2400682A1 (enExample)
EA (1) EA005593B1 (enExample)
FR (1) FR2805813A1 (enExample)
GR (1) GR20010100097A (enExample)
HK (1) HK1054378B (enExample)
HR (1) HRP20020743A2 (enExample)
HU (1) HUP0300078A3 (enExample)
IE (1) IES20010143A2 (enExample)
IL (1) IL151339A0 (enExample)
IS (1) IS6512A (enExample)
IT (1) ITMI20010385A1 (enExample)
MX (1) MXPA02008230A (enExample)
NL (1) NL1017414C1 (enExample)
NO (1) NO20024007L (enExample)
PL (1) PL357178A1 (enExample)
SK (1) SK13662002A3 (enExample)
TR (1) TR200202048T2 (enExample)
UA (1) UA71059C2 (enExample)
WO (1) WO2001062754A1 (enExample)
ZA (2) ZA200206255B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
PL198024B1 (pl) 1999-04-14 2008-05-30 Lundbeck & Co As H Sposób wytwarzania citalopramu, związki pośrednie i ich zastosowanie do wytwarzania citalopramu
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
PT1298124E (pt) 1999-10-25 2007-05-31 Lundbeck & Co As H Método para a preparação de citalopram
US6310222B1 (en) * 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
CN1398263A (zh) 1999-12-28 2003-02-19 H·隆德贝克有限公司 制备西酞普兰的方法
PL198803B1 (pl) 1999-12-30 2008-07-31 Lundbeck & Co As H Sposób wytwarzania 5-cyjano-3H-izobenzofuran-1-onu
EP1254129B1 (en) * 2000-01-14 2003-10-22 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
US6433196B1 (en) * 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
CN1427835A (zh) 2000-03-13 2003-07-02 H·隆德贝克有限公司 5－取代的1－(4－氟苯基)－1,3－二氢异苯并呋喃的分步烷基化
JP2003527387A (ja) * 2000-03-13 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
DK1265882T3 (da) 2000-03-14 2004-06-01 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
KR20020080483A (ko) * 2000-03-16 2002-10-23 하. 룬트벡 아크티에 셀스카브 5-시아노-1-(4-플루오로페닐)-1,3-디히드로이소벤조푸란의제조 방법
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IL144817A0 (en) 2000-08-18 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
SG167655A1 (en) 2000-12-22 2011-01-28 Lundbeck & Co As H Method for the preparation of pure citalopram
PT1281707E (pt) * 2001-08-02 2005-04-29 Infosint Sa Processo para a preparacao de isobenzofuranos 5-substituidos
AU2002330730A1 (en) * 2002-08-14 2004-03-03 Natco Pharma Limited Process for the preparation of high purity citalopram and its pharmaceutically acceptable salts
US8539533B2 (en) * 2003-03-07 2013-09-17 Siemens Enterprise Communications, Inc. System and method for digital personal video stream manager
TR200504022T1 (tr) * 2003-03-24 2006-08-21 Hetero Drugs Limited (S)-sitalopram oksalatın yeni sıvı kristal formları.
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
JP2006176490A (ja) * 2004-11-29 2006-07-06 Sumitomo Chemical Co Ltd ５−フタランカルボニトリル及びシタロプラムの製造方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136193A (en) * 1976-01-14 1979-01-23 Kefalas A/S Anti-depressive substituted 1-dimethylaminopropyl-1-phenyl phthalans
WO1998019511A2 (en) * 1997-11-10 1998-05-14 H. Lundbeck A/S Method for the preparation of citalopram
WO1999030548A2 (en) * 1999-04-14 1999-06-24 H. Lundbeck A/S Method for the preparation of citalopram
EP1095926A2 (en) * 1999-11-01 2001-05-02 SUMIKA FINE CHEMICALS Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
EP1125907A2 (en) * 2000-02-17 2001-08-22 SUMIKA FINE CHEMICALS Co., Ltd. Intermediates for the production of citalopram

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136193A (en) * 1976-01-14 1979-01-23 Kefalas A/S Anti-depressive substituted 1-dimethylaminopropyl-1-phenyl phthalans
WO1998019511A2 (en) * 1997-11-10 1998-05-14 H. Lundbeck A/S Method for the preparation of citalopram
WO1999030548A2 (en) * 1999-04-14 1999-06-24 H. Lundbeck A/S Method for the preparation of citalopram
EP1095926A2 (en) * 1999-11-01 2001-05-02 SUMIKA FINE CHEMICALS Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
EP1125907A2 (en) * 2000-02-17 2001-08-22 SUMIKA FINE CHEMICALS Co., Ltd. Intermediates for the production of citalopram

Also Published As

Publication number Publication date
US20020004604A1 (en) 2002-01-10
BG107015A (bg) 2003-05-30
HUP0300078A3 (en) 2005-02-28
CN1161350C (zh) 2004-08-11
NL1017414C1 (nl) 2001-03-15
ZA200206255B (en) 2003-10-20
CA2400682A1 (en) 2001-08-30
HRP20020743A2 (en) 2003-12-31
HK1054378A1 (en) 2003-11-28
EP1259500A1 (en) 2002-11-27
PL357178A1 (en) 2004-07-26
TR200202048T2 (tr) 2003-01-21
US20030114692A1 (en) 2003-06-19
BR0108947A (pt) 2003-06-03
MXPA02008230A (es) 2003-05-23
IS6512A (is) 2002-08-20
KR20020080438A (ko) 2002-10-23
IES20010143A2 (en) 2001-07-25
SK13662002A3 (sk) 2003-01-09
ITMI20010385A1 (it) 2002-08-26
CN1404475A (zh) 2003-03-19
JP2003524009A (ja) 2003-08-12
NO20024007L (no) 2002-10-07
EA005593B1 (ru) 2005-04-28
EA200200900A1 (ru) 2003-02-27
AU2001235357A1 (en) 2001-09-03
HK1054378B (zh) 2005-04-29
FR2805813A1 (fr) 2001-09-07
IL151339A0 (en) 2003-04-10
NO20024007D0 (no) 2002-08-22
US20030083508A1 (en) 2003-05-01
HUP0300078A2 (en) 2003-05-28
UA71059C2 (uk) 2004-11-15
WO2001062754A1 (en) 2001-08-30
ZA200206699B (en) 2003-11-21
BE1012921A6 (fr) 2001-05-08

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