TR200200013T2 - Tatları gizli kaplanmış granüllerin üretilmesine yönelik metot müessir maddenin derhal salınması. - Google Patents

Tatları gizli kaplanmış granüllerin üretilmesine yönelik metot müessir maddenin derhal salınması.

Info

Publication number
TR200200013T2
TR200200013T2 TR2002/00013T TR200200013T TR200200013T2 TR 200200013 T2 TR200200013 T2 TR 200200013T2 TR 2002/00013 T TR2002/00013 T TR 2002/00013T TR 200200013 T TR200200013 T TR 200200013T TR 200200013 T2 TR200200013 T2 TR 200200013T2
Authority
TR
Turkey
Prior art keywords
granules
immediate release
agent
tastes
hidden
Prior art date
Application number
TR2002/00013T
Other languages
English (en)
Inventor
Nouri Noureddine
Zuccarelli Jean-Marc
Chauveau Charles
Bruna Etienne
Original Assignee
Ethypharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm filed Critical Ethypharm
Publication of TR200200013T2 publication Critical patent/TR200200013T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Seasonings (AREA)
  • Formation And Processing Of Food Products (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Mevcut bulus, müessir maddenin derhal salinmasi ve tadinin gizlenmesine olanak taniyan kapli granüllerin yapilmasina yönelik bir metot ile ilgili olup, en az müessir madde ile bir granül parçalama ajanindan olusan bir toza ait komponentlerin karistirilmasini; akabinde meydana gelen tozun, tane üretmek üzere partikülleri birlestirme becerisindeki en az bir birlestirme ajanini içeren bir tasiyicilar karisimi mevcudiyetinde granüle edilmesini; olusturan granüllerin (tane), en az bir kaplama ajani ile bir membran parçalama ajanini içeren bir süspansiyonun püskürtülmesi ile kaplanmasini ve son olarak, meydana gelen kaplanmis granüllerin kurutulmasini içerir.
TR2002/00013T 1999-07-08 2000-06-30 Tatları gizli kaplanmış granüllerin üretilmesine yönelik metot müessir maddenin derhal salınması. TR200200013T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9909047A FR2795962B1 (fr) 1999-07-08 1999-07-08 Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif

Publications (1)

Publication Number Publication Date
TR200200013T2 true TR200200013T2 (tr) 2002-06-21

Family

ID=9548029

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00013T TR200200013T2 (tr) 1999-07-08 2000-06-30 Tatları gizli kaplanmış granüllerin üretilmesine yönelik metot müessir maddenin derhal salınması.

Country Status (31)

Country Link
US (1) US6660382B2 (tr)
EP (1) EP1194125B1 (tr)
JP (1) JP4749639B2 (tr)
KR (1) KR100767928B1 (tr)
CN (1) CN1220485C (tr)
AT (1) ATE360412T1 (tr)
AU (1) AU760006B2 (tr)
BG (1) BG65615B1 (tr)
BR (1) BR0012250A (tr)
CA (1) CA2375600C (tr)
CY (1) CY1107695T1 (tr)
CZ (1) CZ300154B6 (tr)
DE (1) DE60034565T2 (tr)
DK (1) DK1194125T3 (tr)
DZ (1) DZ3257A1 (tr)
EA (1) EA003161B1 (tr)
ES (1) ES2284507T3 (tr)
FR (1) FR2795962B1 (tr)
HK (1) HK1049119B (tr)
HU (1) HU229568B1 (tr)
IL (2) IL147212A0 (tr)
MA (1) MA25426A1 (tr)
MX (1) MXPA01013354A (tr)
NO (1) NO331256B1 (tr)
NZ (1) NZ516594A (tr)
PL (1) PL201782B1 (tr)
PT (1) PT1194125E (tr)
SK (1) SK287322B6 (tr)
TR (1) TR200200013T2 (tr)
WO (1) WO2001003672A1 (tr)
ZA (1) ZA200200344B (tr)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
AU2001277230A1 (en) * 2000-08-01 2002-02-13 Inhale Therapeutic Systems, Inc. Apparatus and process to produce particles having a narrow size distribution andparticles made thereby
GB0018968D0 (en) * 2000-08-02 2000-09-20 Pfizer Ltd Particulate composition
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
EP1279402B1 (en) * 2001-07-26 2006-11-29 Ethypharm Coated granules of allylamine-or benzylamine-anti-mycotics, process for preparation thereof and orodispersible tablets containing said coated granules
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
FR2834212B1 (fr) * 2001-12-27 2004-07-09 Besins Int Belgique Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
WO2004009058A1 (en) * 2002-07-17 2004-01-29 Eurand Pharmaceuticals Ltd Process for the preparation of pharmaceutical microcapsules with enhanced taste-masking and high dissolution rate
AU2003249478A1 (en) * 2002-07-19 2004-02-09 Ranbaxy Laboratories Limited Taste masked sumatriptan tablets and processes for their preparation
EP1396263A1 (en) * 2002-08-09 2004-03-10 Warner-Lambert Company Film coating for tablets and caplets
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
FR2850275B1 (fr) 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
US20040151771A1 (en) 2003-02-04 2004-08-05 Gin Jerry B. Long-lasting, flavored dosage forms for sustained release of beneficial agents within the mouth
US20040191326A1 (en) * 2003-03-31 2004-09-30 Reo Joseph P. Taste-masking vehicle for coated oxazolidinone particles
CA2524773C (en) 2003-05-08 2014-04-08 Nektar Therapeutics Uk Ltd Particulate coformulations of active substances with excipients
WO2004110492A2 (en) * 2003-06-06 2004-12-23 Glaxo Group Limited Composition comprising triptans and nsaids
WO2005013944A1 (en) * 2003-08-11 2005-02-17 Merck Frosst Canada Ltd. Flavored taste-masked pharmaceutical formulation made using a one-step coating process
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
EP2417969A1 (en) 2004-10-21 2012-02-15 Aptalis Pharmatech, Inc. Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
PE20070698A1 (es) * 2005-11-14 2007-08-17 Teijin Pharma Ltd Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol
JP5123517B2 (ja) * 2005-11-14 2013-01-23 帝人ファーマ株式会社 アンブロキソール口腔内速崩性錠剤
JP5405752B2 (ja) * 2007-01-31 2014-02-05 大日本住友製薬株式会社 被覆された薬物含有粒子および該粒子を含む固形製剤
DE102007019071A1 (de) * 2007-04-23 2008-10-30 Ratiopharm Gmbh Stabilisierte pharmazeutische Zusammensetzung enthaltend Pregabalin
US8703204B2 (en) 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
WO2008135828A2 (en) 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
KR100895942B1 (ko) * 2007-05-08 2009-05-07 조선대학교산학협력단 생약 추출물을 함유하는 구강 내 속붕해성 제제 조성물 및그의 제조 방법
WO2008149230A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate
WO2008149192A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
WO2009073215A1 (en) 2007-12-06 2009-06-11 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
EP2240162A4 (en) 2007-12-06 2013-10-09 Bend Res Inc NANOTE PARTICLES WITH A NON-IONIZABLE POLYMER AND AN AMIN-FUNCTIONALIZED METHACRYLATE COPOLYMER
WO2010018614A1 (ja) * 2008-08-11 2010-02-18 味の素株式会社 呈味性が改善された親水性アミノ酸含有製剤
FR2935084B1 (fr) * 2008-08-19 2011-05-06 Pancosma Sa Pour L Ind Des Produits Biochimiques Additif pour l'alimentation animale et son procede de preparation
KR101069118B1 (ko) 2008-10-22 2011-09-30 경상대학교산학협력단 장용해성 염화콜린의 제조방법 및 이의 방법에 따라 제조되는 염화콜린
CN101879141B (zh) * 2009-05-05 2013-07-17 烟台绿叶动物保健品有限公司 一种掩味替米考星胃溶颗粒制剂
WO2010150221A1 (en) 2009-06-25 2010-12-29 Wockhardt Research Centre Taste masked pharmaceutical compositions of pregabalin
EP2316433A1 (en) * 2009-10-22 2011-05-04 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Orally disintegrating tablets of flurbiprofen
PL2493312T3 (pl) * 2009-10-26 2022-01-03 Merck Sharp & Dohme Corp. Kompozycje farmaceutyczne w postaci ciała stałego zawierające inhibitor integrazy
CA2778273A1 (en) 2009-10-28 2011-05-12 Mcneil-Ppc, Inc. Fast dissolving/disintegrating coating compositions
NZ600256A (en) 2009-12-02 2014-05-30 Aptalis Pharma Ltd Fexofenadine microcapsules and compositions containing them
TR200909613A1 (tr) * 2009-12-22 2011-07-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Pregabalinin farmasötik bileşimleri.
GB2479213B (en) 2010-04-01 2013-07-10 Theravida Inc Pharmaceutical formulations for the treatment of overactive bladder
WO2012005359A1 (ja) 2010-07-09 2012-01-12 帝人ファーマ株式会社 口腔内崩壊錠剤
JP4803686B2 (ja) * 2010-08-31 2011-10-26 協和発酵キリン株式会社 苦味を呈する薬物を含有する顆粒および口腔内崩壊錠
US9808030B2 (en) 2011-02-11 2017-11-07 Grain Processing Corporation Salt composition
KR101481772B1 (ko) 2012-06-19 2015-01-14 주식회사 아리바이오 추출물을 고농도로 함유하는 과립 또는 환의 제조방법
CN102908337B (zh) 2012-10-12 2014-03-05 大连医诺生物有限公司 微囊化氨基酸组合物及其制备方法
US8993041B2 (en) 2012-10-15 2015-03-31 New Jersey Institute Of Technology Taste masked active pharmaceutical powder compositions and processes for making them
JP6572244B2 (ja) 2014-02-25 2019-09-04 オービス バイオサイエンシズ， インク．Ｏｒｂｉｓ Ｂｉｏｓｃｉｅｎｃｅｓ， Ｉｎｃ． 味覚マスキング薬製剤
JP6577024B2 (ja) 2014-05-08 2019-09-18 シーティーシー バイオ インコーポレイテッド 味が遮蔽されたクロミプラミン含有経口投与用薬学製剤
WO2015170939A1 (ko) * 2014-05-08 2015-11-12 주식회사 씨티씨바이오 클로미프라민 함유 맛 차폐된 구강 투여용 약학 제제
JP6841834B2 (ja) 2016-01-20 2021-03-10 テラヴィダ, インコーポレイテッドTheraVida, Inc. 多汗症の処置のための方法および組成物
JP6919119B2 (ja) * 2017-01-23 2021-08-18 日新製薬株式会社 ３位が置換されたγ−アミノ酪酸誘導体を含有する圧縮固形医薬組成物。
FR3078630B1 (fr) 2018-03-08 2021-05-14 Karim Ioualalen Mode de formulation sous forme de solide divise hydrophobe

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
JPS62126122A (ja) 1985-11-27 1987-06-08 Showa Shinyaku Kk 表面コ−テイングされたイブプロフエン顆粒の製法
SE457326B (sv) 1986-02-14 1988-12-19 Lejus Medical Ab Foerfarande foer framstaellning av en snabbt soenderfallande kaerna innehaallande bl a mikrokristallin cellulosa
JPH0780754B2 (ja) 1986-08-06 1995-08-30 エーザイ株式会社 多顆粒型持続性錠剤
IT1200217B (it) * 1986-09-30 1989-01-05 Valducci Roberto Membrana per uso farmaceutico ed industriale
US5358717A (en) * 1989-12-22 1994-10-25 Syntex (U.S.A.) Inc. Directly-compressible naproxen or naproxen sodium compositions
JP2845342B2 (ja) * 1990-04-28 1999-01-13 大正製薬株式会社 ビタミンｄ▲下３▼誘導体含有固形製剤組成物
US5380535A (en) * 1991-05-28 1995-01-10 Geyer; Robert P. Chewable drug-delivery compositions and methods for preparing the same
DE4122217C2 (de) * 1991-07-04 1997-02-13 Merz & Co Gmbh & Co Verfahren zur Herstellung mechanisch stabiler, gut zerfallender Komprimate aus kleinen wirkstoffhaltigen Formkörpern
FR2679451B1 (fr) * 1991-07-22 1994-09-09 Prographarm Laboratoires Comprime multiparticulaire a delitement rapide.
TW271400B (tr) * 1992-07-30 1996-03-01 Pfizer
AUPN605795A0 (en) * 1995-10-19 1995-11-09 F.H. Faulding & Co. Limited Analgesic pharmaceutical composition
AUPO637197A0 (en) 1997-04-23 1997-05-15 F.H. Faulding & Co. Limited Taste-masked pharmaceutical compositions
ID21806A (id) * 1997-01-06 1999-07-29 Pfizer Bentuk penakaran farmasi yang secara cepat dilepaskan dan yang menutup rasa
AR017512A1 (es) * 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
PL197989B1 (pl) * 1997-12-19 2008-05-30 Smithkline Beecham Corp Sposób wytwarzania szybko rozpraszających się tabletek do podawania doustnego, szybko rozpraszający się preparat farmaceutyczny w postaci tabletek i szybko rozpraszająca się, farmaceutycznie dopuszczalna, tabletka do podawania doustnego
FR2785539B1 (fr) 1998-11-06 2004-04-09 Prographarm Laboratoires Particules enrobees d'ibuprofene cristallin granule
US6451345B1 (en) * 2000-01-20 2002-09-17 Eurand Pharmaceuticals Ltd. Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration

Also Published As

Publication number Publication date
HU229568B1 (hu) 2014-02-28
ATE360412T1 (de) 2007-05-15
DZ3257A1 (fr) 2001-01-18
SK287322B6 (sk) 2010-07-07
AU5993600A (en) 2001-01-30
EP1194125A1 (fr) 2002-04-10
JP4749639B2 (ja) 2011-08-17
CZ200218A3 (cs) 2002-04-17
HK1049119B (zh) 2006-05-12
MXPA01013354A (es) 2002-07-09
DK1194125T3 (da) 2007-07-30
FR2795962B1 (fr) 2003-05-09
NO20016308L (no) 2001-12-21
JP2003504324A (ja) 2003-02-04
SK19392001A3 (sk) 2002-04-04
BG106398A (en) 2002-09-30
EA003161B1 (ru) 2003-02-27
IL147212A0 (en) 2002-08-14
NO331256B1 (no) 2011-11-07
IL147212A (en) 2007-05-15
AU760006B2 (en) 2003-05-08
DE60034565T2 (de) 2007-12-27
ZA200200344B (en) 2003-03-26
EA200200136A1 (ru) 2002-06-27
US6660382B2 (en) 2003-12-09
HK1049119A1 (en) 2003-05-02
BR0012250A (pt) 2002-03-26
CN1220485C (zh) 2005-09-28
NZ516594A (en) 2003-11-28
FR2795962A1 (fr) 2001-01-12
BG65615B1 (bg) 2009-03-31
WO2001003672A1 (fr) 2001-01-18
US20020098227A1 (en) 2002-07-25
KR20020015062A (ko) 2002-02-27
PT1194125E (pt) 2007-07-03
NO20016308D0 (no) 2001-12-21
EP1194125B1 (fr) 2007-04-25
ES2284507T3 (es) 2007-11-16
CZ300154B6 (cs) 2009-02-25
MA25426A1 (fr) 2002-04-01
HUP0202062A2 (hu) 2002-12-28
KR100767928B1 (ko) 2007-10-17
CA2375600A1 (fr) 2001-01-18
DE60034565D1 (de) 2007-06-06
CN1373658A (zh) 2002-10-09
PL354257A1 (en) 2003-12-29
HUP0202062A3 (en) 2004-05-28
PL201782B1 (pl) 2009-05-29
CA2375600C (fr) 2011-05-10
CY1107695T1 (el) 2013-04-18

Similar Documents

Publication Publication Date Title
TR200200013T2 (tr) Tatları gizli kaplanmış granüllerin üretilmesine yönelik metot müessir maddenin derhal salınması.
US4079125A (en) Preparation of enteric coated digestive enzyme compositions
SU1364226A3 (ru) Способ микрокапсулировани кислой соли бакампициллина
GB2341077A (en) Carbohydrate-based enzyme granulates
TW347349B (en) A manufacturing method of granulated complex molecular sieve composition having multi-functions
KR950702864A (ko) 우레아 과립제의 제조 방법(process for the production of urea granules)
EP1094788A4 (en) TASTE MASKING WITH CROSCARMELLOSE
HK1077514A1 (en) Taste-masking coated particles, process for the preparation thereof and orodispersible tablets containing said coated particles
WO2006053564A3 (en) Stabilisation of granules comprising active compounds
MX9800301A (es) Polimeros de ioneno tabletizados.
SE9701278D0 (sv) Pulverformigt biogent, av förbenade hjort framställt preparat och på det biogena preparatet baserad livsmedelstillsats
Bartholini et al. Inhibition of 5-hydroxytryptamine liberation from blood platelets by reserpine
JPH10182499A (ja) 可溶性コラーゲンパウダーを担体とする医薬徐放剤
US12084610B2 (en) Compositions and methods for reducing deleterious atmospheric gas emissions from flooded ecosystems
KR20040051461A (ko) 칠보석 분말과 음이온, 은항균제를 이용한 기능성 접착제
JP2006298717A (ja) 土壌散布剤
JPH04200628A (ja) 噴霧乾燥法による微粒子のコーティング方法
JPS61189202A (ja) 農薬用石膏コ−テイングキヤリア
JPS5919907B2 (ja) 緩効性窒素入り複合肥料の肥効調節法
JPH08116921A (ja) 栄養補給剤
Echevarría-Hernández et al. Publication Frequency
JPH03232787A (ja) 被覆粒状肥料およびその製造方法
JPH05137575A (ja) プルラナーゼ固定化無機担体
KR20060003223A (ko) 수면 부유성 확산제제
KR970032869A (ko) 딜티아젬의 서방형 펠렛 제형