TR200103856T2 - Naftiridin türevleri, bunların preparasyon işlemleri, kullanımları ve farmasötik kompozisyonlar. - Google Patents

Naftiridin türevleri, bunların preparasyon işlemleri, kullanımları ve farmasötik kompozisyonlar.

Info

Publication number
TR200103856T2
TR200103856T2 TR2001/03856T TR200103856T TR200103856T2 TR 200103856 T2 TR200103856 T2 TR 200103856T2 TR 2001/03856 T TR2001/03856 T TR 2001/03856T TR 200103856 T TR200103856 T TR 200103856T TR 200103856 T2 TR200103856 T2 TR 200103856T2
Authority
TR
Turkey
Prior art keywords
cell
naftiridine
derivatives
pharmaceutical compositions
preparation processes
Prior art date
Application number
TR2001/03856T
Other languages
English (en)
Inventor
Peyman Anuschirwan
Scheunemann Karlheinz
R. Gadek Thomas
Gourvest Jean-Francois
Ruxer Jean-Marie
Original Assignee
Aventis Pharma Deutschland Gmbh
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland Gmbh, Genentech, Inc. filed Critical Aventis Pharma Deutschland Gmbh
Publication of TR200103856T2 publication Critical patent/TR200103856T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Mevcut bulus, B, G, Z, X, Y, r, s ve t' nin istemlerde belirtilen anlamlara geldigi formül (I)' e ait bilesiklerle, bunlarin fizyolojik açidan tolere edilebilir tuzlari ve ön ilaçlariyla ilgilidir. Formül (I)' e ait bilesikler, farmakolojik açidan aktif degerli bilesiklerdir. Bunlar, vitronektin alici antagonistleri ve hücre yapismasinin önleyicilerdir ve bunlar, hücre-hücre veya hücre-matris etkilesim süreçlerinde vitronektin alicilari ile bunlarin ligantlari arasindaki etkilesime dayanan veya bu etkilesimlerin etkilenmesiyle önlenebilen, iyilestirilebilen veya tedavi edilebilen hastaliklarin terapisi ve profilaksisi için uygundur.
TR2001/03856T 1999-07-02 2000-06-26 Naftiridin türevleri, bunların preparasyon işlemleri, kullanımları ve farmasötik kompozisyonlar. TR200103856T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99112636A EP1065207A1 (en) 1999-07-02 1999-07-02 Naphthyridine derivatives, processes for their preparation, their use, and pharmaceutical compositions comprising them

Publications (1)

Publication Number Publication Date
TR200103856T2 true TR200103856T2 (tr) 2002-06-21

Family

ID=8238482

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03856T TR200103856T2 (tr) 1999-07-02 2000-06-26 Naftiridin türevleri, bunların preparasyon işlemleri, kullanımları ve farmasötik kompozisyonlar.

Country Status (33)

Country Link
US (2) US6743800B1 (tr)
EP (2) EP1065207A1 (tr)
JP (1) JP2003503496A (tr)
KR (1) KR20020015996A (tr)
CN (1) CN1160356C (tr)
AR (1) AR024622A1 (tr)
AT (1) ATE305471T1 (tr)
AU (1) AU775386B2 (tr)
BG (1) BG106257A (tr)
BR (1) BR0012129A (tr)
CA (1) CA2376668C (tr)
CZ (1) CZ20014605A3 (tr)
DE (2) DE60022890T4 (tr)
DK (1) DK1210348T3 (tr)
EA (1) EA004369B1 (tr)
EE (1) EE200100711A (tr)
ES (1) ES2250157T3 (tr)
HK (1) HK1050003B (tr)
HR (1) HRP20010946A2 (tr)
HU (1) HUP0203539A3 (tr)
IL (1) IL147248A0 (tr)
MX (1) MXPA01013435A (tr)
MY (1) MY133246A (tr)
NO (1) NO20016404L (tr)
NZ (1) NZ516058A (tr)
PL (1) PL352280A1 (tr)
SK (1) SK19132001A3 (tr)
TR (1) TR200103856T2 (tr)
TW (1) TW593319B (tr)
UA (1) UA73133C2 (tr)
WO (1) WO2001002398A1 (tr)
YU (1) YU92201A (tr)
ZA (1) ZA200200016B (tr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1065207A1 (en) * 1999-07-02 2001-01-03 Aventis Pharma Deutschland GmbH Naphthyridine derivatives, processes for their preparation, their use, and pharmaceutical compositions comprising them
DE10042655A1 (de) * 2000-08-31 2002-03-14 Aventis Pharma Gmbh Verfahren zur Herstellung von Inhibitoren der Zell-Adhäsion
FR2847254B1 (fr) 2002-11-19 2005-01-28 Aventis Pharma Sa Nouveaux derives antagonistes du recepteur de la vitronectine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les refermant
JP4866610B2 (ja) * 2003-08-18 2012-02-01 富士フイルムファインケミカルズ株式会社 ピリジルテトラヒドロピリジン類およびピリジルピペリジン類
FR2870541B1 (fr) 2004-05-18 2006-07-14 Proskelia Sas Derives de pyrimidines antigonistes du recepteur de la vitronectine
US20110237605A1 (en) * 2010-03-26 2011-09-29 Eric Phillips Molecular Crystal of (4-(1,8-Naphthyridin-2-YL)Piperidin-1-YL)Pyrimidine Derivative
CN107312039B (zh) 2012-08-30 2019-06-25 江苏豪森药业集团有限公司 一种替诺福韦前药的制备方法
HUE063437T2 (hu) 2013-09-24 2024-01-28 Fujifilm Corp Nitrogént tartalmazó vegyületet vagy sóját vagy fémkomplexét tartalmazó gyógyászati készítmény
AU2021267373A1 (en) 2020-05-06 2022-12-08 Ajax Therapeutics, Inc. 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors
WO2023086319A1 (en) 2021-11-09 2023-05-19 Ajax Therapeutics, Inc. 6-he tero aryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU701776B2 (en) * 1994-05-27 1999-02-04 Merck & Co., Inc. Compounds for inhibiting osteoclast-mediated bone resorption
WO1998008940A1 (en) 1996-08-26 1998-03-05 Novo Nordisk A/S A novel endoglucanase
JP2002511052A (ja) * 1996-08-29 2002-04-09 メルク エンド カンパニー インコーポレーテッド インテグリンアンタゴニスト
AU717283B2 (en) * 1996-10-30 2000-03-23 Merck & Co., Inc. Integrin antagonists
DE19653646A1 (de) * 1996-12-20 1998-06-25 Hoechst Ag Substituierte Purinderivate, Verfahren zu deren Herstellung, sie enthaltende Mittel und deren Verwendung
CA2277273C (en) * 1997-01-17 2008-03-25 Merck & Co., Inc. Integrin antagonists
EP0933367A1 (en) * 1997-12-19 1999-08-04 Hoechst Marion Roussel Deutschland GmbH Novel acylguanidine derivates as inhibitors of bone resorption and as vitronectin receptor antagonists
HUP0100520A3 (en) * 1998-01-23 2002-11-28 Genentech Inc Novel sulfonamide derivatives as inhibitors of bone resorption and as inhibitors of cell adhesion
PA8474101A1 (es) * 1998-06-19 2000-09-29 Pfizer Prod Inc Compuestos de pirrolo [2,3-d] pirimidina
US6365589B1 (en) * 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
EP1065207A1 (en) * 1999-07-02 2001-01-03 Aventis Pharma Deutschland GmbH Naphthyridine derivatives, processes for their preparation, their use, and pharmaceutical compositions comprising them
DE10042655A1 (de) * 2000-08-31 2002-03-14 Aventis Pharma Gmbh Verfahren zur Herstellung von Inhibitoren der Zell-Adhäsion
JP2005526709A (ja) * 2002-01-10 2005-09-08 ニューロジェン・コーポレーション メラニン凝集ホルモン受容体リガンド：置換ベンゾイミダゾールアナログ
JP2008047614A (ja) 2006-08-11 2008-02-28 Showa Shell Sekiyu Kk 吸着材を利用した改良型太陽電池モジュール

Also Published As

Publication number Publication date
YU92201A (sh) 2004-07-15
BG106257A (bg) 2002-10-31
SK19132001A3 (sk) 2002-07-02
TW593319B (en) 2004-06-21
MXPA01013435A (es) 2002-07-22
ATE305471T1 (de) 2005-10-15
IL147248A0 (en) 2002-08-14
DE60022890D1 (de) 2006-02-09
EA200200122A1 (ru) 2002-06-27
MY133246A (en) 2007-10-31
WO2001002398A1 (en) 2001-01-11
EP1210348B9 (en) 2006-04-26
UA73133C2 (en) 2005-06-15
BR0012129A (pt) 2002-05-07
US20040198718A1 (en) 2004-10-07
US6743800B1 (en) 2004-06-01
DE60022890T2 (de) 2006-06-29
ES2250157T3 (es) 2006-04-16
CN1372559A (zh) 2002-10-02
CA2376668A1 (en) 2001-01-11
AR024622A1 (es) 2002-10-16
DK1210348T3 (da) 2006-01-16
HUP0203539A3 (en) 2005-01-28
EP1065207A1 (en) 2001-01-03
HUP0203539A2 (hu) 2003-02-28
AU5978700A (en) 2001-01-22
EE200100711A (et) 2003-04-15
CA2376668C (en) 2007-01-02
HRP20010946A2 (en) 2003-02-28
EP1210348A1 (en) 2002-06-05
PL352280A1 (en) 2003-08-11
JP2003503496A (ja) 2003-01-28
CZ20014605A3 (cs) 2002-06-12
CN1160356C (zh) 2004-08-04
NO20016404D0 (no) 2001-12-28
NO20016404L (no) 2002-03-01
EA004369B1 (ru) 2004-04-29
NZ516058A (en) 2003-01-31
ZA200200016B (en) 2003-01-02
EP1210348B1 (en) 2005-09-28
AU775386B2 (en) 2004-07-29
HK1050003A1 (en) 2003-06-06
DE60022890T4 (de) 2007-03-29
KR20020015996A (ko) 2002-03-02
HK1050003B (zh) 2005-04-29

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