TR199900990T2 - Antifungal ve polimer ile kaplanmis çekirdege haiz peletler. - Google Patents

Antifungal ve polimer ile kaplanmis çekirdege haiz peletler.

Info

Publication number
TR199900990T2
TR199900990T2 TR1999/00990T TR9900990T TR199900990T2 TR 199900990 T2 TR199900990 T2 TR 199900990T2 TR 1999/00990 T TR1999/00990 T TR 1999/00990T TR 9900990 T TR9900990 T TR 9900990T TR 199900990 T2 TR199900990 T2 TR 199900990T2
Authority
TR
Turkey
Prior art keywords
pellets
antifungal
polymer coated
coated core
mesh
Prior art date
Application number
TR1999/00990T
Other languages
English (en)
Inventor
Petrus Gerebern Vandecruys Roger
Florent Victor De Cond Valentin
Marie Victor Gilis Paul
Peeters Jozef
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of TR199900990T2 publication Critical patent/TR199900990T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Abstract

Bu bulus, 250-355 m (45-60 göz) seker küre, suda çözünür polimer ve antifungal ajandan olusan kaplama filmi ve yalitim amaçli bir kaplama tabakasi ihtiva eden peletlere, sözü geçen peletleri ihtiva eden farmasötik dozaj formlarina ve sözü geçen peletleri hazirlama islemine iliskindir.
TR1999/00990T 1997-03-26 1998-03-18 Antifungal ve polimer ile kaplanmis çekirdege haiz peletler. TR199900990T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97200914 1997-03-26

Publications (1)

Publication Number Publication Date
TR199900990T2 true TR199900990T2 (tr) 1999-10-21

Family

ID=8228147

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1999/00990T TR199900990T2 (tr) 1997-03-26 1998-03-18 Antifungal ve polimer ile kaplanmis çekirdege haiz peletler.

Country Status (31)

Country Link
EP (1) EP0969821B1 (tr)
JP (1) JP3608800B2 (tr)
KR (1) KR100520936B1 (tr)
CN (1) CN1206984C (tr)
AP (1) AP1227A (tr)
AT (1) ATE241969T1 (tr)
AU (1) AU734248B2 (tr)
BG (1) BG64434B1 (tr)
BR (1) BR9806174A (tr)
CA (1) CA2269501C (tr)
CY (1) CY2384B1 (tr)
CZ (1) CZ295502B6 (tr)
DE (1) DE69815316T2 (tr)
DK (1) DK0969821T3 (tr)
EE (1) EE03904B1 (tr)
ES (1) ES2201485T3 (tr)
HK (1) HK1022840A1 (tr)
HU (1) HU224217B1 (tr)
ID (1) ID21477A (tr)
IL (1) IL129575A (tr)
NO (1) NO325102B1 (tr)
NZ (1) NZ335364A (tr)
OA (1) OA11162A (tr)
PL (1) PL190566B1 (tr)
PT (1) PT969821E (tr)
RU (1) RU2218153C2 (tr)
SI (1) SI0969821T1 (tr)
SK (1) SK284813B6 (tr)
TR (1) TR199900990T2 (tr)
UA (1) UA60318C2 (tr)
WO (1) WO1998042318A1 (tr)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002520351A (ja) 1998-07-17 2002-07-09 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 抗菌・カビ剤及びポリマーを被覆したコアを有するペレット
ES2157731B1 (es) * 1998-07-21 2002-05-01 Liconsa Liberacion Controlada Preparacion farmaceutica oral de un compuesto de actividad antifungica y procedimiento para su preparacion.
BR0009176A (pt) 1999-03-24 2001-12-18 Fmc Corp Partìcula granular, forma de dosagem, métodopara preparar uma partìcula granular, misturaseca, e, formulação granular
KR100432949B1 (ko) * 2000-06-13 2004-05-31 코오롱제약주식회사 생체이용율이 향상된 이트라코나졸의 분립체 조성물과이를 이용한 이트라코나졸 제제 및 그 제조방법
US6663897B2 (en) * 2001-02-06 2003-12-16 Dsm Ip Assets B.V. Oral itraconazole formulations and methods of making the same
ES2275866T3 (es) 2001-02-14 2007-06-16 Tibotec Pharmaceuticals Ltd. 2-(aminosustituido)-benzotiazol-sulfonamidas de amplio esprecto inhibidoras de la proteasa de vih.
NZ528954A (en) 2001-04-09 2005-04-29 Tibotec Pharm Ltd Broadspectrum 2-(substituted-amino)-benzoxazole sulfonamide HIV protease inhibitors
ATE429431T1 (de) 2001-05-11 2009-05-15 Tibotec Pharm Ltd 2-amino-benzoxazol-suphonamide als breitspektrum- hiv-protease-inhibitoren
WO2002100407A1 (en) * 2001-06-12 2002-12-19 Smartrix Technologies Inc. Itraconazole granulations: pharmaceutical formulations for oral administration and method of preparing same
US8071133B2 (en) 2001-08-20 2011-12-06 Stiefel Laboratories, Inc. Oral dosage forms of water insoluble drugs and methods of making the same
KR100942743B1 (ko) 2001-12-21 2010-02-16 티보텍 파마슈티칼즈 리미티드 광범위 스펙트럼 헤테로사이클릭 치환된 페닐 포함설폰아미드 ｈｉｖ 프로테아제 저해제
MY142238A (en) 2002-03-12 2010-11-15 Tibotec Pharm Ltd Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors
JP4674084B2 (ja) 2002-05-17 2011-04-20 テイボテク・フアーマシユーチカルズ・リミテツド 広域スペクトルの置換ベンズイソキサゾールスルホンアミドｈｉｖプロテアーゼ阻害剤
MXPA05001792A (es) 2002-08-14 2005-04-25 Tibotec Pharm Ltd Oxindolsulfonamida sustituida como inhibidores de proteasa de virus de inmunodeficiencia humana de amplio espectro.
KR100557680B1 (ko) * 2002-11-23 2006-03-07 한국유나이티드제약 주식회사 이트라코나졸의 용해도 개선을 위한 펠렛제제 및 그제조방법
SI1438961T2 (sl) * 2003-01-14 2014-12-31 Cimex Pharma Ag Bioekvivalenten sestavek itrakonazola, dispergiranega v hidrofilnem polimeru
ATE357234T1 (de) * 2003-01-14 2007-04-15 Cimex Pharma Ag Zusammensetzung in form eines festen dispersion enthaltend itraconazol und ein hydrophilisches polymer mit einer verbesserten bioverfügbarkeit
CN1845725A (zh) * 2003-08-06 2006-10-11 尼马尔·穆利耶 包含水溶性药物的药物组合物
BRPI0414199A (pt) 2003-09-11 2006-10-31 Tibotec Pharm Ltd inibidores de entrada do vìrus hiv
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
AR048650A1 (es) 2004-05-04 2006-05-10 Tibotec Pharm Ltd Derivados de (1,10b-dihidro-2-(aminocarbonil-fenil)-5h-pirazolo[1,5 c][1,3]benzoxazin-5-il)fenil metanona como inhibidores de la replicacion viral del vih
EP2422780A1 (en) 2004-05-07 2012-02-29 Sequoia Pharmaceuticals, Inc. Resistance-repellent retroviral protease inhibitors
CN1976930B (zh) 2004-05-17 2011-01-19 泰博特克药品有限公司 用作抗感染药物的6,7,8,9-取代的1-苯基-1,5-二氢吡啶并(3,2-b)吲哚-2-酮
JP4879889B2 (ja) 2004-05-17 2012-02-22 テイボテク・フアーマシユーチカルズ・リミテツド ４−置換−１，５−ジヒドロ−ピリド［３，２−ｂ］インドール−２−オン
CN1953983B (zh) 2004-05-17 2010-05-26 泰博特克药品有限公司 1-杂环基-1,5-二氢-吡啶并[3,2-b]吲哚-2-酮
JP2009534311A (ja) 2006-04-03 2009-09-24 テイボテク・フアーマシユーチカルズ・リミテツド ＨＩＶ阻害性３，４−ジヒドロ−イミダゾ［４，５−ｂ］ピリジン−５−オン
EP2068844A4 (en) * 2006-09-04 2013-01-23 Panacea Biotec Ltd PROGRAMMABLE RELEASE TECHNIQUE BY FLOATING SYSTEM
KR100809903B1 (ko) * 2006-09-05 2008-03-06 주식회사유한양행 안정화된 클로피도그렐-함유 입자, 그의 제조방법, 및 이를포함하는 약학 조성물
CN101283984B (zh) * 2007-04-12 2010-05-26 永胜药品工业股份有限公司 高生物使用率的经杀真菌剂和聚合物涂覆的核心微粒状物
JP2008280254A (ja) * 2007-05-08 2008-11-20 Everest Pharm Industrial Co Ltd 生体に使用される比率が高い、殺菌剤と重合物を塗粧してる核心微粒状物
US8313527B2 (en) 2007-11-05 2012-11-20 Allergan, Inc. Soft prosthesis shell texturing method
EP2224923A4 (en) 2007-11-28 2013-05-15 Sequoia Pharmaceuticals Inc COMPOSITIONS AND METHOD FOR INHIBITING ZYTOCHROM P450 2D6
EP2257160B1 (en) 2008-02-21 2017-07-05 Sequoia Pharmaceuticals, Inc. Diamide inhibitors of cytochrome p450
US9050184B2 (en) 2008-08-13 2015-06-09 Allergan, Inc. Dual plane breast implant
US8877822B2 (en) 2010-09-28 2014-11-04 Allergan, Inc. Porogen compositions, methods of making and uses
US9205577B2 (en) 2010-02-05 2015-12-08 Allergan, Inc. Porogen compositions, methods of making and uses
US9138309B2 (en) 2010-02-05 2015-09-22 Allergan, Inc. Porous materials, methods of making and uses
SG174658A1 (en) 2010-04-01 2011-10-28 Theravida Inc Pharmaceutical formulations for the treatment of overactive bladder
US11202853B2 (en) 2010-05-11 2021-12-21 Allergan, Inc. Porogen compositions, methods of making and uses
AU2011252017B2 (en) * 2010-05-11 2015-07-16 Allergan, Inc. Porogen compositions, methods of making and uses
US8679279B2 (en) 2010-11-16 2014-03-25 Allergan, Inc. Methods for creating foam-like texture
CN102100678B (zh) * 2011-02-18 2012-10-17 天津力生制药股份有限公司 伊曲康唑硫酸盐微丸及其制备方法
CA2895083A1 (en) 2012-12-13 2014-06-19 Allergan, Inc. Device and method for making a variable surface breast implant
US10092392B2 (en) 2014-05-16 2018-10-09 Allergan, Inc. Textured breast implant and methods of making same
WO2017127073A1 (en) 2016-01-20 2017-07-27 Theravida, Inc. Methods and compositions for treating hyperhidrosis
CA3097176A1 (en) * 2018-04-16 2019-10-24 Bristol-Myers Squibb Company Apixaban formulations
CN114767636B (zh) * 2022-04-11 2023-11-07 苏州中化药品工业有限公司 伊曲康唑微丸、制备方法及伊曲康唑微丸胶囊

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346123A1 (de) * 1983-12-21 1985-06-27 Janssen Pharmaceutica, N.V., Beerse Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung
GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
PH30929A (en) * 1992-09-03 1997-12-23 Janssen Pharmaceutica Nv Beads having a core coated with an antifungal and a polymer.
EP0914100A1 (en) * 1996-06-28 1999-05-12 Schering Corporation Oral composition comprising a triazole antifungal compound

Also Published As

Publication number Publication date
RU2218153C2 (ru) 2003-12-10
EE03904B1 (et) 2002-12-16
IL129575A (en) 2004-06-20
WO1998042318A1 (en) 1998-10-01
HK1022840A1 (en) 2000-08-25
CZ295502B6 (cs) 2005-08-17
NZ335364A (en) 2000-08-25
EP0969821A1 (en) 2000-01-12
AP9901516A0 (en) 1999-06-30
CA2269501C (en) 2005-11-08
CN1244796A (zh) 2000-02-16
CY2384B1 (en) 2004-06-04
PL335542A1 (en) 2000-04-25
PT969821E (pt) 2003-10-31
CA2269501A1 (en) 1998-10-01
KR20000052971A (ko) 2000-08-25
NO992114D0 (no) 1999-04-30
DK0969821T3 (da) 2003-09-15
ID21477A (id) 1999-06-17
CN1206984C (zh) 2005-06-22
DE69815316D1 (de) 2003-07-10
NO325102B1 (no) 2008-02-04
OA11162A (en) 2003-04-16
AU734248B2 (en) 2001-06-07
KR100520936B1 (ko) 2005-10-17
ATE241969T1 (de) 2003-06-15
BR9806174A (pt) 1999-10-19
AU7210798A (en) 1998-10-20
CZ139899A3 (cs) 1999-10-13
HUP0002056A2 (hu) 2000-12-28
HUP0002056A3 (en) 2001-01-29
IL129575A0 (en) 2000-02-29
JP3608800B2 (ja) 2005-01-12
SK54499A3 (en) 2000-01-18
AP1227A (en) 2003-11-24
EE9900453A (et) 2000-04-17
SK284813B6 (sk) 2005-12-01
BG103356A (en) 2000-03-31
HU224217B1 (hu) 2005-06-28
JP2001520663A (ja) 2001-10-30
UA60318C2 (uk) 2003-10-15
SI0969821T1 (en) 2003-10-31
NO992114L (no) 1999-08-26
DE69815316T2 (de) 2004-04-29
EP0969821B1 (en) 2003-06-04
ES2201485T3 (es) 2004-03-16
PL190566B1 (pl) 2005-12-30
BG64434B1 (en) 2005-02-28

Similar Documents

Publication Publication Date Title
TR199900990T2 (tr) Antifungal ve polimer ile kaplanmis çekirdege haiz peletler.
PT1140012E (pt) Conversao de capsulas de gelatina cheias com liquido em sistemas de libertacao controlada por camadas multiplas
ATE268593T1 (de) Bupropionhydrochlorid enthaltende tabletten mit gesteuerter wirkstoffabgabe
TR200000139T2 (tr) Geliştirilmiş hızlı parçalanan çok-tanecikli tablet.
CA2346341A1 (en) Encapsulated chemicals for use in controlled time release applications and methods
WO2007014061A3 (en) Coated tables with zero-order or near zero-order release kinetics
NO912470D0 (no) Fremgangsmaate til fremstilling av et komposittlag paa et underlag i et apparat som inneholder elektrolytt i fast tilstand.
GR1002349B (el) Νεες φαρμακευτικες συνθεσεις διαχυτικα-οσμωτικα ελεγχομενης απελευθερωσης φαρμακου και μεθοδοι παρασκευης τους.
WO1999029354A3 (en) Method and apparatus creating a radioactive layer on an implantable substrate
NL192819B (nl) Met een hydroxypropylmethylcellulosefilm beklede tablet van ranitidine hydrochloride.
WO2004035644A3 (en) Self-healing organosiloxane materials containing reversible and energy-dispersive crosslinking domains
ES8308724A1 (es) Procediento para la fabricacion de un articulo solido coloreado portador al memos de una talla en resalte o sebresaliente
BR9906712A (pt) Péletes que apresentam um núcleo revestido com um antifúngico e um polìmero
AU2003262812A1 (en) Coated particles with prolonged release and tablets containing same
EP0826491A3 (en) Film with substrate layer containing antiblocking agent
GB2343117A (en) Benzimidazole pharmaceutical composition and process of preparation
DE60020827D1 (de) Enzym enthaltende verbundteilchen mit einer säuresperrbeschichtung sowie einer physikalischen sperrbeschichtung
DK1169032T3 (da) Ketoprofen-mikrogranuler, fremgangsmåde til fremstilling deraf og farmaceutiske præparater
DE69113645T2 (de) Beschichteter heisssiegelbarer aromatischer Polyimidfilm mit hoher Druckfestigkeit.
NL185780C (nl) Werkwijze voor het modificeren van een epoxyhars, werkwijze ter bereiding van bekledingsmaterialen en voorwerpen daarmee bekleed.
MY109271A (en) Ozone-friendly correction fluid containing a butyl methacrylate copolymer as a film forming binder
ZA919510B (en) Pharmaceutical compositions
EP0050436A3 (en) Coated, heat-sealable aromatic polymer film
ES430315A1 (es) Perfeccionamientos en los sistemas dispensadores de agentesinsecticidas.
NO20005426L (no) Pelleter med en kjerne som er belagt med et lipidsenkende middel og en polymer