GB2343117A - Benzimidazole pharmaceutical composition and process of preparation - Google Patents
Benzimidazole pharmaceutical composition and process of preparationInfo
- Publication number
- GB2343117A GB2343117A GB9927132A GB9927132A GB2343117A GB 2343117 A GB2343117 A GB 2343117A GB 9927132 A GB9927132 A GB 9927132A GB 9927132 A GB9927132 A GB 9927132A GB 2343117 A GB2343117 A GB 2343117A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pharmaceutical composition
- preparation
- benzimidazole
- core
- moisture resistant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A pharmaceutical composition which is a solid pellet comprising an inert core, a benzimidazole in or on the core, a moisture resistant coating around the core, the moisture resistant coating comprising at least one hydrophobic material, and an enteric coating around the moisture resistant coating.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9710800.5A GB9710800D0 (en) | 1997-05-23 | 1997-05-23 | Pharmaceutical composition and method of preparing it |
PCT/GB1998/001465 WO1998052564A1 (en) | 1997-05-23 | 1998-05-21 | Benzimidazole pharmaceutical composition and process of preparation |
Publications (3)
Publication Number | Publication Date |
---|---|
GB9927132D0 GB9927132D0 (en) | 2000-01-12 |
GB2343117A true GB2343117A (en) | 2000-05-03 |
GB2343117B GB2343117B (en) | 2001-07-25 |
Family
ID=10813043
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB9710800.5A Ceased GB9710800D0 (en) | 1997-05-23 | 1997-05-23 | Pharmaceutical composition and method of preparing it |
GB9927132A Expired - Fee Related GB2343117B (en) | 1997-05-23 | 1998-05-21 | Benzimidazole pharmaceutical composition and process of preparation |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB9710800.5A Ceased GB9710800D0 (en) | 1997-05-23 | 1997-05-23 | Pharmaceutical composition and method of preparing it |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0983067A1 (en) |
AU (1) | AU729038B2 (en) |
CA (1) | CA2290824A1 (en) |
GB (2) | GB9710800D0 (en) |
WO (1) | WO1998052564A1 (en) |
ZA (1) | ZA984266B (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1037634B1 (en) * | 1997-12-08 | 2005-09-07 | ALTANA Pharma AG | Oral administration form comprising a proton pump inhibitor (e.g.pantoprazole) |
FR2774288B1 (en) * | 1998-01-30 | 2001-09-07 | Ethypharm Sa | GASTROPROTEGED OMEPRAZOLE MICROGRANULES, PROCESS FOR OBTAINING AND PHARMACEUTICAL PREPARATIONS |
FR2793688B1 (en) | 1999-05-21 | 2003-06-13 | Ethypharm Lab Prod Ethiques | GASTROPROTEGED MICROGRANULES, PROCESS FOR OBTAINING AND PHARMACEUTICAL PREPARATIONS |
AU775995B2 (en) | 1999-06-07 | 2004-08-19 | Nycomed Gmbh | Novel preparation and administration form comprising an acid-labile active compound |
US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
ES2168043B1 (en) | 1999-09-13 | 2003-04-01 | Esteve Labor Dr | PHARMACEUTICAL FORM ORAL SOLID MODIFIED RELEASE CONTAINING A COMPOSITE OF BENCIMIDAZOL LABIL IN THE MIDDLE ACID. |
DE60036014T2 (en) * | 1999-10-20 | 2008-04-30 | Eisai R&D Management Co., Ltd. | METHOD FOR STABILIZING BENZIMIDAZOLE COMPOUNDS |
AR021347A1 (en) | 1999-10-20 | 2002-07-17 | Cipla Ltd | A PHARMACEUTICAL COMPOSITION CONTAINING SISPHOSPHONIC ACID (S) OR SALT (S) OF THE SAME AND A PREPARATION PROCESS OF THE SAME |
WO2001032185A1 (en) * | 1999-11-02 | 2001-05-10 | Cipla Ltd. | A pharmaceutical composition containing bisphosphonic acid(s) or salt(s) thereof and a process of preparing thereof |
DE19959419A1 (en) * | 1999-12-09 | 2001-06-21 | Ratiopharm Gmbh | Stable pharmaceutical preparations comprising a benzimidazole and process for their preparation |
WO2004075881A1 (en) * | 2003-02-28 | 2004-09-10 | Ranbaxy Laboratories Limited | Stable pharmaceutical composition of rabeprazole and processes for their preparation |
WO2005027876A1 (en) * | 2003-08-28 | 2005-03-31 | Ranbaxy Laboratories Limited | Pharmaceutical compositions of benzimidazole and processes for their preparation |
WO2005032554A1 (en) * | 2003-10-03 | 2005-04-14 | Astron Research Pvt. Ltd | A novel transmucosal delivery system |
JP2007536349A (en) | 2004-05-07 | 2007-12-13 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | Novel pharmaceutical dosage form and production method |
WO2006011159A2 (en) * | 2004-06-21 | 2006-02-02 | Torrent Pharmaceuticals Limited | Stabilized pharmaceutical composition containing rabeprazole sodium with improved bioavailability |
ITMI20062290A1 (en) * | 2006-11-28 | 2008-05-29 | Monteres S R L | TABLETS STABLE WITH STORAGE BASED ON BENZIMIDAZOLE DERIVATIVES COATED WITH GASTRO-RESISTANT FILM |
CN101822671A (en) * | 2009-03-06 | 2010-09-08 | 信谊药厂 | Rabeprazde composition and preparation method thereof |
CN103202818A (en) * | 2012-01-15 | 2013-07-17 | 山东新时代药业有限公司 | An enteric-coated tablet containing D-rabeprazole or a pharmaceutically acceptable salt thereof, and a preparation method therefor |
CN102772387B (en) * | 2012-08-09 | 2014-02-12 | 广东帅广医药有限公司 | Lansoprazole composition enteric capsule and preparation method thereof |
EP3292862A1 (en) | 2016-09-07 | 2018-03-14 | Sandoz Ag | Omeprazole formulations |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5920219A (en) * | 1982-07-26 | 1984-02-01 | Shin Etsu Chem Co Ltd | Preparation of enteric coated pharmaceutical |
EP0342522A1 (en) * | 1988-05-18 | 1989-11-23 | Eisai Co., Ltd. | Peroral preparation of an acid-unstable compound |
EP0247983B1 (en) * | 1986-04-30 | 1993-01-07 | Aktiebolaget Hässle | New pharmaceutical preparation for oral use |
WO1997012581A2 (en) * | 1995-09-21 | 1997-04-10 | Pharma Pass L.L.C. | Novel composition containing an acid-labile omeprazole and process for its preparation |
-
1997
- 1997-05-23 GB GBGB9710800.5A patent/GB9710800D0/en not_active Ceased
-
1998
- 1998-05-20 ZA ZA984266A patent/ZA984266B/en unknown
- 1998-05-21 WO PCT/GB1998/001465 patent/WO1998052564A1/en not_active Application Discontinuation
- 1998-05-21 GB GB9927132A patent/GB2343117B/en not_active Expired - Fee Related
- 1998-05-21 CA CA002290824A patent/CA2290824A1/en not_active Abandoned
- 1998-05-21 EP EP98922927A patent/EP0983067A1/en not_active Withdrawn
- 1998-05-21 AU AU75390/98A patent/AU729038B2/en not_active Ceased
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5920219A (en) * | 1982-07-26 | 1984-02-01 | Shin Etsu Chem Co Ltd | Preparation of enteric coated pharmaceutical |
EP0247983B1 (en) * | 1986-04-30 | 1993-01-07 | Aktiebolaget Hässle | New pharmaceutical preparation for oral use |
EP0342522A1 (en) * | 1988-05-18 | 1989-11-23 | Eisai Co., Ltd. | Peroral preparation of an acid-unstable compound |
WO1997012581A2 (en) * | 1995-09-21 | 1997-04-10 | Pharma Pass L.L.C. | Novel composition containing an acid-labile omeprazole and process for its preparation |
Non-Patent Citations (1)
Title |
---|
PATENT ABSTRACTS OF JAPAN vol.008, no.106 (c-223), 18/5/1984& JP59020219A (SHINETSU KAGAKU KOGYO KK) * |
Also Published As
Publication number | Publication date |
---|---|
AU729038B2 (en) | 2001-01-25 |
WO1998052564A1 (en) | 1998-11-26 |
ZA984266B (en) | 1999-01-20 |
CA2290824A1 (en) | 1998-11-26 |
GB9710800D0 (en) | 1997-07-23 |
GB2343117B (en) | 2001-07-25 |
GB9927132D0 (en) | 2000-01-12 |
AU7539098A (en) | 1998-12-11 |
EP0983067A1 (en) | 2000-03-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20020521 |