GB2343117A - Benzimidazole pharmaceutical composition and process of preparation - Google Patents

Benzimidazole pharmaceutical composition and process of preparation

Info

Publication number
GB2343117A
GB2343117A GB9927132A GB9927132A GB2343117A GB 2343117 A GB2343117 A GB 2343117A GB 9927132 A GB9927132 A GB 9927132A GB 9927132 A GB9927132 A GB 9927132A GB 2343117 A GB2343117 A GB 2343117A
Authority
GB
United Kingdom
Prior art keywords
pharmaceutical composition
preparation
benzimidazole
core
moisture resistant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB9927132A
Other versions
GB2343117B (en
GB9927132D0 (en
Inventor
Yusuf Khwaja Hamied
Vinay G Nayak
Geena Malhotra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cipla Ltd
Original Assignee
Cipla Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd filed Critical Cipla Ltd
Publication of GB9927132D0 publication Critical patent/GB9927132D0/en
Publication of GB2343117A publication Critical patent/GB2343117A/en
Application granted granted Critical
Publication of GB2343117B publication Critical patent/GB2343117B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A pharmaceutical composition which is a solid pellet comprising an inert core, a benzimidazole in or on the core, a moisture resistant coating around the core, the moisture resistant coating comprising at least one hydrophobic material, and an enteric coating around the moisture resistant coating.
GB9927132A 1997-05-23 1998-05-21 Benzimidazole pharmaceutical composition and process of preparation Expired - Fee Related GB2343117B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9710800.5A GB9710800D0 (en) 1997-05-23 1997-05-23 Pharmaceutical composition and method of preparing it
PCT/GB1998/001465 WO1998052564A1 (en) 1997-05-23 1998-05-21 Benzimidazole pharmaceutical composition and process of preparation

Publications (3)

Publication Number Publication Date
GB9927132D0 GB9927132D0 (en) 2000-01-12
GB2343117A true GB2343117A (en) 2000-05-03
GB2343117B GB2343117B (en) 2001-07-25

Family

ID=10813043

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB9710800.5A Ceased GB9710800D0 (en) 1997-05-23 1997-05-23 Pharmaceutical composition and method of preparing it
GB9927132A Expired - Fee Related GB2343117B (en) 1997-05-23 1998-05-21 Benzimidazole pharmaceutical composition and process of preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB9710800.5A Ceased GB9710800D0 (en) 1997-05-23 1997-05-23 Pharmaceutical composition and method of preparing it

Country Status (6)

Country Link
EP (1) EP0983067A1 (en)
AU (1) AU729038B2 (en)
CA (1) CA2290824A1 (en)
GB (2) GB9710800D0 (en)
WO (1) WO1998052564A1 (en)
ZA (1) ZA984266B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1037634B1 (en) * 1997-12-08 2005-09-07 ALTANA Pharma AG Oral administration form comprising a proton pump inhibitor (e.g.pantoprazole)
FR2774288B1 (en) * 1998-01-30 2001-09-07 Ethypharm Sa GASTROPROTEGED OMEPRAZOLE MICROGRANULES, PROCESS FOR OBTAINING AND PHARMACEUTICAL PREPARATIONS
FR2793688B1 (en) 1999-05-21 2003-06-13 Ethypharm Lab Prod Ethiques GASTROPROTEGED MICROGRANULES, PROCESS FOR OBTAINING AND PHARMACEUTICAL PREPARATIONS
AU775995B2 (en) 1999-06-07 2004-08-19 Nycomed Gmbh Novel preparation and administration form comprising an acid-labile active compound
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
ES2168043B1 (en) 1999-09-13 2003-04-01 Esteve Labor Dr PHARMACEUTICAL FORM ORAL SOLID MODIFIED RELEASE CONTAINING A COMPOSITE OF BENCIMIDAZOL LABIL IN THE MIDDLE ACID.
DE60036014T2 (en) * 1999-10-20 2008-04-30 Eisai R&D Management Co., Ltd. METHOD FOR STABILIZING BENZIMIDAZOLE COMPOUNDS
AR021347A1 (en) 1999-10-20 2002-07-17 Cipla Ltd A PHARMACEUTICAL COMPOSITION CONTAINING SISPHOSPHONIC ACID (S) OR SALT (S) OF THE SAME AND A PREPARATION PROCESS OF THE SAME
WO2001032185A1 (en) * 1999-11-02 2001-05-10 Cipla Ltd. A pharmaceutical composition containing bisphosphonic acid(s) or salt(s) thereof and a process of preparing thereof
DE19959419A1 (en) * 1999-12-09 2001-06-21 Ratiopharm Gmbh Stable pharmaceutical preparations comprising a benzimidazole and process for their preparation
WO2004075881A1 (en) * 2003-02-28 2004-09-10 Ranbaxy Laboratories Limited Stable pharmaceutical composition of rabeprazole and processes for their preparation
WO2005027876A1 (en) * 2003-08-28 2005-03-31 Ranbaxy Laboratories Limited Pharmaceutical compositions of benzimidazole and processes for their preparation
WO2005032554A1 (en) * 2003-10-03 2005-04-14 Astron Research Pvt. Ltd A novel transmucosal delivery system
JP2007536349A (en) 2004-05-07 2007-12-13 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング Novel pharmaceutical dosage form and production method
WO2006011159A2 (en) * 2004-06-21 2006-02-02 Torrent Pharmaceuticals Limited Stabilized pharmaceutical composition containing rabeprazole sodium with improved bioavailability
ITMI20062290A1 (en) * 2006-11-28 2008-05-29 Monteres S R L TABLETS STABLE WITH STORAGE BASED ON BENZIMIDAZOLE DERIVATIVES COATED WITH GASTRO-RESISTANT FILM
CN101822671A (en) * 2009-03-06 2010-09-08 信谊药厂 Rabeprazde composition and preparation method thereof
CN103202818A (en) * 2012-01-15 2013-07-17 山东新时代药业有限公司 An enteric-coated tablet containing D-rabeprazole or a pharmaceutically acceptable salt thereof, and a preparation method therefor
CN102772387B (en) * 2012-08-09 2014-02-12 广东帅广医药有限公司 Lansoprazole composition enteric capsule and preparation method thereof
EP3292862A1 (en) 2016-09-07 2018-03-14 Sandoz Ag Omeprazole formulations

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5920219A (en) * 1982-07-26 1984-02-01 Shin Etsu Chem Co Ltd Preparation of enteric coated pharmaceutical
EP0342522A1 (en) * 1988-05-18 1989-11-23 Eisai Co., Ltd. Peroral preparation of an acid-unstable compound
EP0247983B1 (en) * 1986-04-30 1993-01-07 Aktiebolaget Hässle New pharmaceutical preparation for oral use
WO1997012581A2 (en) * 1995-09-21 1997-04-10 Pharma Pass L.L.C. Novel composition containing an acid-labile omeprazole and process for its preparation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5920219A (en) * 1982-07-26 1984-02-01 Shin Etsu Chem Co Ltd Preparation of enteric coated pharmaceutical
EP0247983B1 (en) * 1986-04-30 1993-01-07 Aktiebolaget Hässle New pharmaceutical preparation for oral use
EP0342522A1 (en) * 1988-05-18 1989-11-23 Eisai Co., Ltd. Peroral preparation of an acid-unstable compound
WO1997012581A2 (en) * 1995-09-21 1997-04-10 Pharma Pass L.L.C. Novel composition containing an acid-labile omeprazole and process for its preparation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol.008, no.106 (c-223), 18/5/1984& JP59020219A (SHINETSU KAGAKU KOGYO KK) *

Also Published As

Publication number Publication date
AU729038B2 (en) 2001-01-25
WO1998052564A1 (en) 1998-11-26
ZA984266B (en) 1999-01-20
CA2290824A1 (en) 1998-11-26
GB9710800D0 (en) 1997-07-23
GB2343117B (en) 2001-07-25
GB9927132D0 (en) 2000-01-12
AU7539098A (en) 1998-12-11
EP0983067A1 (en) 2000-03-08

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20020521