SU721002A3 - Способ получени бензоморфанов или их солей или рацемической смеси или их оптических изомеров - Google Patents

Способ получени бензоморфанов или их солей или рацемической смеси или их оптических изомеров Download PDF

Info

Publication number
SU721002A3
SU721002A3 SU752128785A SU2128785A SU721002A3 SU 721002 A3 SU721002 A3 SU 721002A3 SU 752128785 A SU752128785 A SU 752128785A SU 2128785 A SU2128785 A SU 2128785A SU 721002 A3 SU721002 A3 SU 721002A3
Authority
SU
USSR - Soviet Union
Prior art keywords
methyl
mmol
benzomorfan
methoxy
solution
Prior art date
Application number
SU752128785A
Other languages
English (en)
Russian (ru)
Inventor
Альфред Монтзка Томас
Даниель Матискелла Джон
Original Assignee
Бристоль Мейерз Компани (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бристоль Мейерз Компани (Фирма) filed Critical Бристоль Мейерз Компани (Фирма)
Application granted granted Critical
Publication of SU721002A3 publication Critical patent/SU721002A3/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/26Benzomorphans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/562Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
SU752128785A 1974-04-18 1975-04-18 Способ получени бензоморфанов или их солей или рацемической смеси или их оптических изомеров SU721002A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46200774A 1974-04-18 1974-04-18

Publications (1)

Publication Number Publication Date
SU721002A3 true SU721002A3 (ru) 1980-03-05

Family

ID=23834846

Family Applications (1)

Application Number Title Priority Date Filing Date
SU752128785A SU721002A3 (ru) 1974-04-18 1975-04-18 Способ получени бензоморфанов или их солей или рацемической смеси или их оптических изомеров

Country Status (23)

Country Link
JP (3) JPS6218552B2 (hu)
BE (1) BE828054A (hu)
CA (1) CA1040630A (hu)
CH (1) CH623812A5 (hu)
CS (1) CS199586B2 (hu)
DD (1) DD119787A5 (hu)
DE (1) DE2517220A1 (hu)
DK (2) DK155999C (hu)
FI (1) FI60564C (hu)
FR (1) FR2267774B1 (hu)
GB (1) GB1493420A (hu)
HU (1) HU173039B (hu)
IE (1) IE41003B1 (hu)
IL (1) IL47114A (hu)
LU (1) LU72315A1 (hu)
NL (1) NL159971C (hu)
NO (1) NO143155C (hu)
OA (1) OA04983A (hu)
PH (1) PH12067A (hu)
SE (1) SE427181B (hu)
SU (1) SU721002A3 (hu)
YU (1) YU93275A (hu)
ZA (1) ZA752471B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01179624A (ja) * 1988-01-12 1989-07-17 Matsushita Refrig Co Ltd 生鮮物貯蔵装置
GB2442535B (en) 2006-10-05 2011-07-13 Ngf Europ Ltd Method and articles

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE34235B1 (en) * 1969-06-04 1975-03-19 Acf Chemiefarma Nv 6,7-benzomorphans and their preparation

Also Published As

Publication number Publication date
YU93275A (en) 1982-02-28
JPS60120868A (ja) 1985-06-28
DK155999B (da) 1989-06-12
IE41003B1 (en) 1979-09-26
BE828054A (fr) 1975-10-17
FI60564B (fi) 1981-10-30
ZA752471B (en) 1976-03-31
DE2517220C2 (hu) 1990-04-19
IL47114A0 (en) 1975-06-25
HU173039B (hu) 1979-02-28
LU72315A1 (hu) 1976-03-17
SE427181B (sv) 1983-03-14
SE7504469L (sv) 1975-10-20
CA1040630A (en) 1978-10-17
DE2517220A1 (de) 1975-11-06
JPS6218552B2 (hu) 1987-04-23
DK155999C (da) 1989-11-06
IE41003L (en) 1975-10-18
PH12067A (en) 1978-10-30
FI751106A (hu) 1975-10-19
JPS6127390B2 (hu) 1986-06-25
NO143155B (no) 1980-09-15
FR2267774B1 (hu) 1978-08-04
JPH0119387B2 (hu) 1989-04-11
FR2267774A1 (hu) 1975-11-14
IL47114A (en) 1979-01-31
JPS60142964A (ja) 1985-07-29
NO751371L (hu) 1975-10-21
AU8025875A (en) 1976-10-21
NL7504648A (nl) 1975-10-21
NL159971C (nl) 1979-09-17
OA04983A (fr) 1980-11-30
DK194088A (da) 1988-04-08
GB1493420A (en) 1977-11-30
JPS50142568A (hu) 1975-11-17
CH623812A5 (en) 1981-06-30
DK166375A (da) 1975-10-19
CS199586B2 (en) 1980-07-31
DK194088D0 (da) 1988-04-08
DD119787A5 (hu) 1976-05-12
FI60564C (fi) 1982-02-10
NO143155C (no) 1980-12-29

Similar Documents

Publication Publication Date Title
US4243807A (en) 4-Phenoxymethyl-piperidines
US4581456A (en) Processes for preparing picenadol precursors and novel intermediates thereof
EP0028017A1 (en) 3-Piperidinone-4-carboxylic acid derivatives
US4360519A (en) Analgesic method using a morpholine compound
WO1996036636A1 (en) Process for preparing 4-aryl-piperidine derivatives
JPH06500076A (ja) ピペリジン化合物、その合成およびその使用方法
SU721002A3 (ru) Способ получени бензоморфанов или их солей или рацемической смеси или их оптических изомеров
US2723276A (en) Coumarin derivatives and process for the manufacture thereof
Baltzly et al. Catalytic Debenzylation. III. The Influence of α-Substitution on the Ease of Hydrogenolysis1
FI62528B (fi) Ett nytt foerfarande foer framstaellning av 1-(3,5-dihydroxifenyl)-1-hydroxi-2-(1-metyl-2-(4-hydroxifenyl)-etyl)-aminoetan
US3631039A (en) 2-amino ethyl-2-hydroxy - 6-vinyl tetrahydropyrans tautomers and optical enantiomers thereof
US4236009A (en) Method of preparing 4A-arylhexahydro-1H-2-pyrindines and 4A-aryloctahydroisoquinolines
SU727140A3 (ru) Способ получени производных 14-гидроксиморфинана
US2636881A (en) 3-substituted, 3-aryl, 2-pipecolines and salts thereof
US2974146A (en) 3-piperidyl benzhydryl ethers
CA2433605A1 (en) Process for preparing (.plusmn.) trans-4-p-fluorophenyl-3-hydroxymethyl-1-methylpiperidine
NO174669B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiopyranylaminer
US2650231A (en) Aminovalerolactones and method for their production
US4663460A (en) Intermediates for picenadol
US2485662A (en) Alpha-(aminoalkyl)-stilbenes
EP0059989A1 (en) 2,3- and 3,4-dehydro-5-phenylmorphans and their preparation
US4031101A (en) Cis-2,6-dimethyl-α,α-diphenyl-1-piperidinebutanol compounds
US4931558A (en) Processes for preparing intermediates of picenadol
HU189348B (en) Process for producing l-/bis/hydroxy-methyl/-methyl/-3,4-dihydro- or 1,2,3,4-tetrahydro-isoquinolin derivatives
KR800000852B1 (ko) 4-(4-코로로페닐)-4-히드록시-N, N-디메틸-α, α-디페닐-1-피페리딘부탄 아미드 및 그의 부가염의 제조방법.