SU1039442A3 - Способ получени производных фенилпиперазина - Google Patents

Способ получени производных фенилпиперазина Download PDF

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Publication number
SU1039442A3
SU1039442A3 SU802890551A SU2890551A SU1039442A3 SU 1039442 A3 SU1039442 A3 SU 1039442A3 SU 802890551 A SU802890551 A SU 802890551A SU 2890551 A SU2890551 A SU 2890551A SU 1039442 A3 SU1039442 A3 SU 1039442A3
Authority
SU
USSR - Soviet Union
Prior art keywords
piperazine
mmol
trifluoromethylphenyl
mixture
added
Prior art date
Application number
SU802890551A
Other languages
English (en)
Russian (ru)
Inventor
Хайнц Хэк Ханс
Корнелиус Хиллен Федо
Original Assignee
Дюфар Интернэшнл Рисерч Б.В. (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дюфар Интернэшнл Рисерч Б.В. (Фирма) filed Critical Дюфар Интернэшнл Рисерч Б.В. (Фирма)
Application granted granted Critical
Publication of SU1039442A3 publication Critical patent/SU1039442A3/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
SU802890551A 1979-03-01 1980-02-27 Способ получени производных фенилпиперазина SU1039442A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7901633 1979-03-01

Publications (1)

Publication Number Publication Date
SU1039442A3 true SU1039442A3 (ru) 1983-08-30

Family

ID=19832723

Family Applications (1)

Application Number Title Priority Date Filing Date
SU802890551A SU1039442A3 (ru) 1979-03-01 1980-02-27 Способ получени производных фенилпиперазина

Country Status (20)

Country Link
EP (1) EP0015615B1 (enExample)
JP (1) JPS55141478A (enExample)
AT (1) ATE2219T1 (enExample)
AU (1) AU532411B2 (enExample)
CA (1) CA1138461A (enExample)
CS (1) CS216525B2 (enExample)
DD (1) DD151408A5 (enExample)
DE (1) DE3061561D1 (enExample)
DK (1) DK84380A (enExample)
ES (3) ES488988A0 (enExample)
FI (1) FI800588A7 (enExample)
GR (1) GR67005B (enExample)
HU (1) HU182070B (enExample)
IE (1) IE49526B1 (enExample)
IL (1) IL59489A (enExample)
PH (1) PH17025A (enExample)
PL (1) PL126161B1 (enExample)
SU (1) SU1039442A3 (enExample)
YU (1) YU54680A (enExample)
ZA (1) ZA801119B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8005133A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met antiagressieve werking.
NL8005131A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met analgetische werking.
US4457931A (en) * 1982-09-27 1984-07-03 Selvi & C. S.P.A. Piperazine derivatives with anticholinergic and/or antihistaminic activity
JPH0660160B2 (ja) * 1985-12-13 1994-08-10 テルモ株式会社 アミド誘導体およびこれを含有する抗アレルギ−剤
US5340812A (en) * 1989-04-22 1994-08-23 John Wyeth & Brother, Limited Piperazine derivatives
IE64038B1 (en) * 1989-04-22 1995-06-28 Wyeth John & Brother Ltd Tertiary alkyl functionalized piperazine derivatives
HUT54666A (en) * 1989-04-22 1991-03-28 Wyeth John & Brother Ltd Process for producing peperazine derivatives and pharmaceutical compositions containing them
US5382583A (en) * 1989-04-22 1995-01-17 John Wyeth & Brother, Limited Piperazine derivatives
DK203990D0 (da) * 1990-08-24 1990-08-24 Novo Nordisk As Piperazinylderivater
GB9200293D0 (en) * 1992-01-08 1992-02-26 Wyeth John & Brother Ltd Piperazine derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2833770A (en) * 1958-05-06 Chj-chj
US2722529A (en) * 1955-11-01 Amides of certain l-amevoalkyl-x-phenyl
BE788280A (fr) * 1971-09-04 1973-02-28 Pfizer Nouvelles 1-(3-trifluoro-methyl-phenyl)-4-((amido cyclique)- alkyl) piperazines et composition pharmaceutique les contenant
GB1443598A (en) * 1973-07-06 1976-07-21 Acraf 1- 3-acetylaminopropyl-4-2,5-dichlorophenyl-piperazine
FR2306694A1 (fr) * 1975-04-07 1976-11-05 Parcor Derives de la piperazine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
1. Вейганд-Хильгетаг. Методы эксперимента в органической химии. М., Хими , 1968, с.445, *

Also Published As

Publication number Publication date
JPS55141478A (en) 1980-11-05
DK84380A (da) 1980-09-02
IE49526B1 (en) 1985-10-16
DE3061561D1 (en) 1983-02-17
IL59489A (en) 1984-05-31
PH17025A (en) 1984-05-17
PL222294A1 (enExample) 1980-12-01
YU54680A (en) 1983-09-30
CA1138461A (en) 1982-12-28
IE800405L (en) 1980-09-01
ES8200884A1 (es) 1981-11-16
DD151408A5 (de) 1981-10-21
ES8200883A1 (es) 1981-11-16
EP0015615B1 (en) 1983-01-12
AU5584880A (en) 1980-09-04
EP0015615A1 (en) 1980-09-17
AU532411B2 (en) 1983-09-29
GR67005B (enExample) 1981-05-18
CS216525B2 (en) 1982-11-26
ES8106898A1 (es) 1981-09-01
FI800588A7 (fi) 1981-01-01
ES495105A0 (es) 1981-11-16
HU182070B (en) 1983-12-28
ES488988A0 (es) 1981-09-01
IL59489A0 (en) 1980-05-30
ZA801119B (en) 1981-09-30
ATE2219T1 (de) 1983-01-15
ES495106A0 (es) 1981-11-16
PL126161B1 (en) 1983-07-30

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