AU532411B2 - Phenyl piperazine derivatives - Google Patents

Phenyl piperazine derivatives

Info

Publication number
AU532411B2
AU532411B2 AU55848/80A AU5584880A AU532411B2 AU 532411 B2 AU532411 B2 AU 532411B2 AU 55848/80 A AU55848/80 A AU 55848/80A AU 5584880 A AU5584880 A AU 5584880A AU 532411 B2 AU532411 B2 AU 532411B2
Authority
AU
Australia
Prior art keywords
formula
compound
pharmaceutically acceptable
salts
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU55848/80A
Other languages
English (en)
Other versions
AU5584880A (en
Inventor
Hans Heinz Haeck
Feddo Cornelius Hillen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duphar International Research BV
Original Assignee
Duphar International Research BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar International Research BV filed Critical Duphar International Research BV
Publication of AU5584880A publication Critical patent/AU5584880A/en
Application granted granted Critical
Publication of AU532411B2 publication Critical patent/AU532411B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
AU55848/80A 1979-03-01 1980-02-25 Phenyl piperazine derivatives Ceased AU532411B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL7901633 1979-03-01
NL7901633 1979-03-01

Publications (2)

Publication Number Publication Date
AU5584880A AU5584880A (en) 1980-09-04
AU532411B2 true AU532411B2 (en) 1983-09-29

Family

ID=19832723

Family Applications (1)

Application Number Title Priority Date Filing Date
AU55848/80A Ceased AU532411B2 (en) 1979-03-01 1980-02-25 Phenyl piperazine derivatives

Country Status (20)

Country Link
EP (1) EP0015615B1 (enExample)
JP (1) JPS55141478A (enExample)
AT (1) ATE2219T1 (enExample)
AU (1) AU532411B2 (enExample)
CA (1) CA1138461A (enExample)
CS (1) CS216525B2 (enExample)
DD (1) DD151408A5 (enExample)
DE (1) DE3061561D1 (enExample)
DK (1) DK84380A (enExample)
ES (3) ES488988A0 (enExample)
FI (1) FI800588A7 (enExample)
GR (1) GR67005B (enExample)
HU (1) HU182070B (enExample)
IE (1) IE49526B1 (enExample)
IL (1) IL59489A (enExample)
PH (1) PH17025A (enExample)
PL (1) PL126161B1 (enExample)
SU (1) SU1039442A3 (enExample)
YU (1) YU54680A (enExample)
ZA (1) ZA801119B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8005133A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met antiagressieve werking.
NL8005131A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met analgetische werking.
US4457931A (en) * 1982-09-27 1984-07-03 Selvi & C. S.P.A. Piperazine derivatives with anticholinergic and/or antihistaminic activity
JPH0660160B2 (ja) * 1985-12-13 1994-08-10 テルモ株式会社 アミド誘導体およびこれを含有する抗アレルギ−剤
IL94151A (en) * 1989-04-22 1995-08-31 Wyeth John & Brother Ltd History of piperazine, their preparation and pharmaceutical preparations containing them
EP0955296A3 (en) * 1989-04-22 2000-01-19 American Home Products Corporation Tertiary alkyl functionalized piperazine derivatives
US5340812A (en) * 1989-04-22 1994-08-23 John Wyeth & Brother, Limited Piperazine derivatives
US5382583A (en) * 1989-04-22 1995-01-17 John Wyeth & Brother, Limited Piperazine derivatives
DK203990D0 (da) * 1990-08-24 1990-08-24 Novo Nordisk As Piperazinylderivater
GB9200293D0 (en) * 1992-01-08 1992-02-26 Wyeth John & Brother Ltd Piperazine derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2722529A (en) * 1955-11-01 Amides of certain l-amevoalkyl-x-phenyl
US2833770A (en) * 1958-05-06 Chj-chj
BE788280A (fr) * 1971-09-04 1973-02-28 Pfizer Nouvelles 1-(3-trifluoro-methyl-phenyl)-4-((amido cyclique)- alkyl) piperazines et composition pharmaceutique les contenant
GB1443598A (en) * 1973-07-06 1976-07-21 Acraf 1- 3-acetylaminopropyl-4-2,5-dichlorophenyl-piperazine
FR2306694A1 (fr) * 1975-04-07 1976-11-05 Parcor Derives de la piperazine

Also Published As

Publication number Publication date
IL59489A0 (en) 1980-05-30
PL222294A1 (enExample) 1980-12-01
YU54680A (en) 1983-09-30
ATE2219T1 (de) 1983-01-15
DK84380A (da) 1980-09-02
ES8200883A1 (es) 1981-11-16
CA1138461A (en) 1982-12-28
DE3061561D1 (en) 1983-02-17
ES8106898A1 (es) 1981-09-01
PH17025A (en) 1984-05-17
FI800588A7 (fi) 1981-01-01
ES495105A0 (es) 1981-11-16
JPS55141478A (en) 1980-11-05
IE49526B1 (en) 1985-10-16
EP0015615A1 (en) 1980-09-17
SU1039442A3 (ru) 1983-08-30
ES8200884A1 (es) 1981-11-16
DD151408A5 (de) 1981-10-21
AU5584880A (en) 1980-09-04
ZA801119B (en) 1981-09-30
PL126161B1 (en) 1983-07-30
ES488988A0 (es) 1981-09-01
EP0015615B1 (en) 1983-01-12
GR67005B (enExample) 1981-05-18
IL59489A (en) 1984-05-31
HU182070B (en) 1983-12-28
ES495106A0 (es) 1981-11-16
IE800405L (en) 1980-09-01
CS216525B2 (en) 1982-11-26

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