SMT201400154B - Composti di triazolopiridina come inibitori di chinasi pim - Google Patents

Composti di triazolopiridina come inibitori di chinasi pim

Info

Publication number
SMT201400154B
SMT201400154B SM201400154T SM201400154T SMT201400154B SM T201400154 B SMT201400154 B SM T201400154B SM 201400154 T SM201400154 T SM 201400154T SM 201400154 T SM201400154 T SM 201400154T SM T201400154 B SMT201400154 B SM T201400154B
Authority
SM
San Marino
Prior art keywords
kinase inhibitors
pim kinase
triazolopyridine compounds
triazolopyridine
compounds
Prior art date
Application number
SM201400154T
Other languages
English (en)
Italian (it)
Inventor
Robert Kirk Delisle
Mark C Munson
Bryson Rast
George T Topalov
Qian Zhao
Shelley Allen
Laura L Celeste
Gregg T Davis
Julie Marie Greschuk
Stefan D Gross
Erik James Hicken
Leila J Jackson
Joseph P Lyssikatos
Nicholas C Kallan
Fredrik P Marmsater
Jed Pheneger
John E Robinson
Stephen T Schlachter
Dale A Wright
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of SMT201400154B publication Critical patent/SMT201400154B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SM201400154T 2008-08-19 2014-10-21 Composti di triazolopiridina come inibitori di chinasi pim SMT201400154B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8995208P 2008-08-19 2008-08-19
US17527709P 2009-05-04 2009-05-04
PCT/US2009/054193 WO2010022076A1 (en) 2008-08-19 2009-08-18 Triazolopyridine compounds as pim kinase inhibitors

Publications (1)

Publication Number Publication Date
SMT201400154B true SMT201400154B (it) 2015-01-15

Family

ID=41227138

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201400154T SMT201400154B (it) 2008-08-19 2014-10-21 Composti di triazolopiridina come inibitori di chinasi pim

Country Status (17)

Country Link
US (1) US8575145B2 (pl)
EP (1) EP2334677B1 (pl)
JP (2) JP5518072B2 (pl)
CN (1) CN102186851B (pl)
AR (1) AR073079A1 (pl)
CA (1) CA2734831C (pl)
DK (1) DK2334677T3 (pl)
ES (1) ES2439501T3 (pl)
HR (1) HRP20131140T1 (pl)
PL (1) PL2334677T3 (pl)
PT (1) PT2334677E (pl)
RS (1) RS53079B (pl)
SI (1) SI2334677T1 (pl)
SM (1) SMT201400154B (pl)
TW (1) TWI496779B (pl)
UY (1) UY32057A (pl)
WO (1) WO2010022076A1 (pl)

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EP2334677B1 (en) 2013-10-09
CN102186851B (zh) 2013-06-12
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DK2334677T3 (da) 2013-11-18
JP2012500277A (ja) 2012-01-05
HRP20131140T1 (hr) 2014-01-03
TW201008940A (en) 2010-03-01
EP2334677A1 (en) 2011-06-22
SI2334677T1 (sl) 2013-12-31
PT2334677E (pt) 2013-11-26
US20110144085A1 (en) 2011-06-16
ES2439501T3 (es) 2014-01-23
CA2734831C (en) 2017-04-18
WO2010022076A1 (en) 2010-02-25
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CA2734831A1 (en) 2010-02-25
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