SK52393A3 - Novel pilocarpine erivatives and process for their preparation - Google Patents

Novel pilocarpine erivatives and process for their preparation Download PDF

Info

Publication number
SK52393A3
SK52393A3 SK523-93A SK52393A SK52393A3 SK 52393 A3 SK52393 A3 SK 52393A3 SK 52393 A SK52393 A SK 52393A SK 52393 A3 SK52393 A3 SK 52393A3
Authority
SK
Slovakia
Prior art keywords
formula
acid
compound
defined above
pilocarpine
Prior art date
Application number
SK523-93A
Other languages
English (en)
Slovak (sk)
Inventor
Tomi Jarvinen
Pekka Peura
Pekka Suhonen
Arto Urtti
Hannu Hanhijarvi
Esko Pohjala
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of SK52393A3 publication Critical patent/SK52393A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK523-93A 1990-11-30 1991-11-27 Novel pilocarpine erivatives and process for their preparation SK52393A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI905930A FI98815C (fi) 1990-11-30 1990-11-30 Menetelmä uusien, farmakologisesti käyttökelpoisten bispilokarpiinihapon esterijohdannaisten valmistamiseksi
PCT/FI1991/000359 WO1992009583A1 (en) 1990-11-30 1991-11-27 Novel pilocarpine derivatives and process for their preparation

Publications (1)

Publication Number Publication Date
SK52393A3 true SK52393A3 (en) 1994-01-12

Family

ID=8531500

Family Applications (1)

Application Number Title Priority Date Filing Date
SK523-93A SK52393A3 (en) 1990-11-30 1991-11-27 Novel pilocarpine erivatives and process for their preparation

Country Status (19)

Country Link
EP (1) EP0559700B1 (et)
JP (1) JP3094232B2 (et)
KR (1) KR930703264A (et)
AT (1) ATE192144T1 (et)
AU (1) AU664958B2 (et)
CA (1) CA2096444A1 (et)
CZ (1) CZ282229B6 (et)
DE (1) DE69132143T2 (et)
EE (1) EE9400143A (et)
FI (1) FI98815C (et)
HU (1) HUT67273A (et)
LT (1) LT3532B (et)
LV (1) LV10094B (et)
NO (1) NO304228B1 (et)
NZ (1) NZ240781A (et)
PL (2) PL167773B1 (et)
RU (1) RU2100352C1 (et)
SK (1) SK52393A3 (et)
WO (1) WO1992009583A1 (et)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0642501A1 (en) * 1992-05-29 1995-03-15 Leiras Oy Novel pilocarpine derivatives and process for their preparation
GB9310965D0 (en) * 1993-05-27 1993-07-14 Ucb Sa 2-hydroxy-3-(1h-imidazol-4-yl)alkyl)benzenecarboximidamides
AU6973094A (en) * 1993-06-24 1995-01-17 Leiras Oy Composition for ophthalmic use
SE501482C2 (sv) * 1993-06-24 1995-02-27 Leiras Oy Komposition för topisk administration av bispilokarpinsyradiestrar till ögat i form av en vattenlösning
SE9302201D0 (sv) 1993-06-24 1993-06-24 Leiras Oy Composition for ophthalmic use
DE4334135A1 (de) * 1993-10-07 1995-04-13 Merck Patent Gmbh Verfahren zur Herstellung von Pilocarpin-Derivaten

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4061722A (en) 1976-04-26 1977-12-06 Interx Research Corporation Selected quaternary ammonium salts of pilocarpine useful in reducing intraocular pressure in warm-blooded animals
IL69593A (en) * 1982-09-17 1988-09-30 Bundegaard Hans Pilocarpine prodrugs,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0559700A1 (en) 1993-09-15
CZ282229B6 (cs) 1997-06-11
RU2100352C1 (ru) 1997-12-27
FI905930A (fi) 1992-05-31
CA2096444A1 (en) 1992-05-31
JPH06504270A (ja) 1994-05-19
WO1992009583A1 (en) 1992-06-11
HUT67273A (en) 1995-03-28
NO931960L (no) 1993-05-28
EP0559700B1 (en) 2000-04-26
DE69132143T2 (de) 2000-12-14
CZ102593A3 (en) 1994-04-13
NZ240781A (en) 1993-12-23
PL168715B1 (pl) 1996-03-29
LV10094A (lv) 1994-05-10
LT3532B (en) 1995-11-27
LV10094B (en) 1995-02-20
FI98815B (fi) 1997-05-15
NO931960D0 (no) 1993-05-28
JP3094232B2 (ja) 2000-10-03
HU9301569D0 (en) 1993-09-28
ATE192144T1 (de) 2000-05-15
FI98815C (fi) 1997-08-25
FI905930A0 (fi) 1990-11-30
EE9400143A (et) 1995-12-15
DE69132143D1 (de) 2000-05-31
LTIP577A (en) 1994-12-27
NO304228B1 (no) 1998-11-16
AU664958B2 (en) 1995-12-07
PL167773B1 (pl) 1995-11-30
AU8939891A (en) 1992-06-25
KR930703264A (ko) 1993-11-29

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