SK50672005A3 - Prípravok imunoglobulínu a spôsob jeho prípravy - Google Patents

Prípravok imunoglobulínu a spôsob jeho prípravy Download PDF

Info

Publication number
SK50672005A3
SK50672005A3 SK5067-2005A SK50672005A SK50672005A3 SK 50672005 A3 SK50672005 A3 SK 50672005A3 SK 50672005 A SK50672005 A SK 50672005A SK 50672005 A3 SK50672005 A3 SK 50672005A3
Authority
SK
Slovakia
Prior art keywords
composition
polysorbate
amount
antibody
present
Prior art date
Application number
SK5067-2005A
Other languages
English (en)
Slovak (sk)
Inventor
David J. Burke
Shaun E. Buckley
Sherwood Russ Lehrman
Barbara Horsey O�Connor
James Callaway
Original Assignee
Elan Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32869424&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK50672005(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Elan Pharmaceuticals, Inc. filed Critical Elan Pharmaceuticals, Inc.
Publication of SK50672005A3 publication Critical patent/SK50672005A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nutrition Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK5067-2005A 2003-02-10 2004-02-09 Prípravok imunoglobulínu a spôsob jeho prípravy SK50672005A3 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44581803P 2003-02-10 2003-02-10
PCT/US2004/003873 WO2004071439A2 (fr) 2003-02-10 2004-02-09 Preparation d'immunoglobuline et son procede de production

Publications (1)

Publication Number Publication Date
SK50672005A3 true SK50672005A3 (sk) 2006-03-02

Family

ID=32869424

Family Applications (1)

Application Number Title Priority Date Filing Date
SK5067-2005A SK50672005A3 (sk) 2003-02-10 2004-02-09 Prípravok imunoglobulínu a spôsob jeho prípravy

Country Status (29)

Country Link
US (7) US20050053598A1 (fr)
EP (4) EP3417875B1 (fr)
JP (3) JP4728948B2 (fr)
KR (1) KR20050110628A (fr)
CN (2) CN103040732B (fr)
AR (1) AR043144A1 (fr)
AU (2) AU2004210679A1 (fr)
CA (1) CA2515444C (fr)
CL (1) CL2004000224A1 (fr)
CY (2) CY1120574T1 (fr)
DK (2) DK2236154T3 (fr)
ES (1) ES2819011T3 (fr)
HK (1) HK1182021A1 (fr)
HU (1) HUE051878T2 (fr)
IL (1) IL170008A (fr)
MX (1) MXPA05008409A (fr)
MY (1) MY162623A (fr)
NO (1) NO346070B1 (fr)
PE (1) PE20050190A1 (fr)
PT (2) PT2236154T (fr)
RU (1) RU2358763C2 (fr)
SI (2) SI3417875T1 (fr)
SK (1) SK50672005A3 (fr)
TR (1) TR201808801T4 (fr)
TW (1) TWI367766B (fr)
UA (1) UA82685C2 (fr)
UY (1) UY28184A1 (fr)
WO (1) WO2004071439A2 (fr)
ZA (1) ZA200506159B (fr)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2359697C2 (ru) 2002-02-25 2009-06-27 Элан Фармасьютикалз, Инк. Введение средств для лечения воспаления
US9415102B2 (en) * 2002-09-06 2016-08-16 Alexion Pharmaceuticals, Inc. High concentration formulations of anti-C5 antibodies
US20050271660A1 (en) 2002-09-06 2005-12-08 Alexion Pharmaceuticals, Inc. Nebulization of monoclonal antibodies for treating pulmonary diseases
NZ538384A (en) * 2002-09-06 2009-04-30 Alexion Pharma Inc Treatment for asthma using a compound which binds to or otherwise blocks the generation and/or activity of one or more complement components reptors, such as, C5a receptors
SI3417875T1 (sl) * 2003-02-10 2021-01-29 Biogen Ma Inc. Formulacija imunoglobulina in metode za njegovo pripravo
US20060104968A1 (en) 2003-03-05 2006-05-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
US8277810B2 (en) * 2003-11-04 2012-10-02 Novartis Vaccines & Diagnostics, Inc. Antagonist anti-CD40 antibodies
RS57852B1 (sr) * 2004-04-02 2018-12-31 Swedish Orphan Biovitrum Ab Publ Postupci za smanjenje agregacije il-1ra
CA2478458A1 (fr) * 2004-08-20 2006-02-20 Michael Panzara Traitement de la sclerose en plaques pediatrique
JO3000B1 (ar) 2004-10-20 2016-09-05 Genentech Inc مركبات أجسام مضادة .
CN101102792A (zh) * 2004-11-19 2008-01-09 比奥根艾迪克Ma公司 治疗多发性硬化
SI1865986T1 (sl) * 2005-03-08 2016-05-31 Pfizer Products Inc. Sestavki protitelesa proti CTLA-4
AU2006247039B2 (en) * 2005-05-19 2011-03-03 Amgen Inc. Compositions and methods for increasing the stability of antibodies
AR057807A1 (es) * 2005-09-12 2007-12-19 Novimmune Sa Formulaciones de anticuerpo anti-cd3
US9309316B2 (en) 2005-12-20 2016-04-12 Bristol-Myers Squibb Company Stable subcutaneous protein formulations and uses thereof
SI3219328T1 (sl) 2005-12-29 2020-10-30 Janssen Biotech, Inc. Človeška protitelesa proti-IL-23, sestavki, postopki in uporabe
EP3124029A1 (fr) 2006-03-15 2017-02-01 Alexion Pharmaceuticals, Inc. Traitement de patients souffrant d'hémoglobinurie paroxystique nocturne par un inhibiteur de complément
TW200806315A (en) * 2006-04-26 2008-02-01 Wyeth Corp Novel formulations which stabilize and inhibit precipitation of immunogenic compositions
CA2663892A1 (fr) * 2006-09-25 2008-04-03 Medimmune, Llc Formulations d'anticorps stabilisees et leurs utilisations
TW200831129A (en) * 2006-10-06 2008-08-01 Amgen Inc Stable formulations
AU2007309616B2 (en) * 2006-10-20 2011-10-06 Amgen Inc. Stable polypeptide formulations
AR064826A1 (es) * 2007-01-09 2009-04-29 Wyeth Corp Formulaciones de anticuerpos anti-il-13 y usos de los mismos. dispositivos, parche y jeringa
ATE535157T1 (de) * 2007-02-12 2011-12-15 Lassaad Boujbel Sterile sucralose-lösung ohne konservierungsmittel und dessen herstellungsverfahren
US20090208492A1 (en) * 2007-06-14 2009-08-20 Elan Pharmaceuticals, Inc. Lyophilized Immunoglobulin Formulations and Methods of Preparation
SI2170390T1 (sl) * 2007-06-14 2019-02-28 Biogen Ma Inc. Oblike protitelesa natalizumab
WO2009003010A2 (fr) * 2007-06-25 2008-12-31 Becton, Dickinson And Company Procédés d'évaluation de l'agrégation d'une protéine dans une suspension comprenant un organopolysiloxane, et articles médicaux enrobés d'organopolysiloxane contenant une solution de protéines
ES2543735T3 (es) * 2007-10-22 2015-08-21 Becton Dickinson And Company Artículos médicos revestidos con organopolisiloxano que contienen una disolución de proteína y un tensioactivo no iónico
US8883146B2 (en) 2007-11-30 2014-11-11 Abbvie Inc. Protein formulations and methods of making same
TWI489994B (zh) 2008-03-17 2015-07-01 Baxter Healthcare Sa 供免疫球蛋白及玻尿酸酶之皮下投藥之用的組合及方法
WO2009124294A2 (fr) * 2008-04-05 2009-10-08 Lpath, Inc. Compositions pharmaceutiques destinées à lier la sphingosine-1-phosphate
US8772461B2 (en) 2008-04-15 2014-07-08 Grifols Therapeutics Inc. Two-stage ultrafiltration/diafiltration
CA2734919C (fr) 2008-08-27 2016-08-16 Schering Corporation Formulations lyophilisees d'anticorps anti-il-23p19 modifies
TWI516501B (zh) * 2008-09-12 2016-01-11 禮納特神經系統科學公司 Ｐｃｓｋ９拮抗劑類
KR20110096553A (ko) * 2008-11-28 2011-08-30 아보트 러보러터리즈 안정한 항체 조성물 및 이의 안정화 방법
US20110263481A1 (en) * 2008-12-29 2011-10-27 Samyang Corporation Pharmaceutical Composition of Lyophilized Formulation and Preparation Method of the Same
FR2940617B1 (fr) * 2008-12-30 2012-04-20 Fractionnement Et Des Biotechonologies Lab Franc Composition d'immunoglobulines g
MX2011010971A (es) * 2009-04-17 2012-01-19 Biogen Idec Inc Composiciones y metodos para tratar leucemia mielogena aguda.
RU2560701C2 (ru) * 2009-05-04 2015-08-20 Эббви Байотекнолоджи Лтд. Стабильные композиции с высокими концентрациями белков антител человека против tnf-альфа
BR112012005890B1 (pt) * 2009-09-17 2023-01-17 Takeda Pharmaceutical Company Limited Co-formulação estável de hialuronidase e imunoglobulina e métodos de utilização da mesma
WO2011075185A1 (fr) 2009-12-18 2011-06-23 Oligasis Conjugués de polymère de phosphorylcholine à médicament ciblé
WO2011104381A2 (fr) 2010-02-26 2011-09-01 Novo Nordisk A/S Compositions stables contenant des anticorps
EP3466977B1 (fr) 2010-04-16 2022-01-05 Biogen MA Inc. Anticorps anti-vla-4
MX2012013586A (es) 2010-05-28 2013-01-24 Novo Nordisk As Composiciones multi-dosis estables que comprenden un anticuerpo y un conservante.
EP3626263A1 (fr) 2010-06-04 2020-03-25 Wyeth LLC Formulations vaccinales
EP3578205A1 (fr) 2010-08-06 2019-12-11 ModernaTX, Inc. Compositions pharmaceutiques a base d'acides nucléiques modifiés et leur utilisation medicale
PL2616090T3 (pl) 2010-09-17 2023-12-18 Takeda Pharmaceutical Company Limited Stabilizowanie immunoglobulin poprzez wodną formulację z histydyną o ph od słabo kwaśnego do obojętnego
CN104531812A (zh) 2010-10-01 2015-04-22 现代治疗公司 设计核酸及其使用方法
SI3326645T1 (sl) 2010-10-25 2020-09-30 Biogen Ma Inc. Metode za determinacijo razlik v alfa- 4 integrin aktivnosti s korelacijo razlik v SVCAM in/ali SMADCAM nivojih
DK2637690T3 (da) 2010-11-11 2017-01-02 Abbvie Biotechnology Ltd Flydende ANTI-TNF-alpha-antistofformuleringer med høj koncentration
AR083847A1 (es) 2010-11-15 2013-03-27 Novartis Ag Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40
JP2014511687A (ja) 2011-03-31 2014-05-19 モデルナ セラピューティクス インコーポレイテッド 工学操作された核酸の送達および製剤
JP6014116B2 (ja) 2011-03-31 2016-10-25 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． ヒト・プログラム死受容体ｐｄ−１に対する抗体の安定製剤および関連治療
MX349119B (es) * 2011-05-26 2017-07-12 Glaxosmithkline Biologicals Sa Vacuna de virus de dengue inactivado.
DK2726090T3 (da) 2011-07-01 2020-01-20 Biogen Ma Inc Argininfri tnfr: fc-fusionspolypeptidsammensætninger
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
ES2911677T3 (es) 2011-10-03 2022-05-20 Modernatx Inc Nucleósidos, nucleótidos y ácidos nucleicos modificados, y sus usos
RS63244B1 (sr) 2011-12-16 2022-06-30 Modernatx Inc Kompozicije modifikovane mrna
WO2013112438A1 (fr) * 2012-01-23 2013-08-01 Regeneron Pharmaceuticals, Inc. Formulations stabilisées contenant des anticorps anti-ang2
EP2830658B1 (fr) * 2012-03-26 2018-10-10 Sanofi Formulations stables d'agent de liaison à igg4
US9592289B2 (en) 2012-03-26 2017-03-14 Sanofi Stable IgG4 based binding agent formulations
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9878056B2 (en) 2012-04-02 2018-01-30 Modernatx, Inc. Modified polynucleotides for the production of cosmetic proteins and peptides
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US20140010861A1 (en) 2012-04-02 2014-01-09 modeRNA Therapeutics Modified polynucleotides for the production of proteins associated with human disease
US20140004131A1 (en) 2012-05-04 2014-01-02 Novartis Ag Antibody formulation
AR091902A1 (es) * 2012-07-25 2015-03-11 Hanmi Pharm Ind Co Ltd Formulacion liquida de un conjugado de insulina de accion prolongada
US8883979B2 (en) 2012-08-31 2014-11-11 Bayer Healthcare Llc Anti-prolactin receptor antibody formulations
EP2727602A1 (fr) * 2012-10-31 2014-05-07 Takeda GmbH Procédé de préparation d'une formulation liquide à concentration élevée d'un anticorps
LT2922554T (lt) 2012-11-26 2022-06-27 Modernatx, Inc. Terminaliai modifikuota rnr
UA117466C2 (uk) 2012-12-13 2018-08-10 Мерк Шарп Енд Доме Корп. СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
SI3041513T1 (sl) 2013-09-08 2020-11-30 Kodiak Sciences Inc. Zwitterionski polimerni konjugati faktorja VIII
US10023626B2 (en) 2013-09-30 2018-07-17 Modernatx, Inc. Polynucleotides encoding immune modulating polypeptides
KR20160067219A (ko) 2013-10-03 2016-06-13 모더나 세라퓨틱스, 인코포레이티드 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드
CN106163567B (zh) 2013-11-21 2021-06-11 根马布股份公司 抗体-药物缀合物冻干制剂
WO2015095568A1 (fr) * 2013-12-18 2015-06-25 Kelvin Lee Réduction de l'activité d'une lipase dans des formulations de produits
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
EP3207128B1 (fr) 2014-10-17 2022-07-27 Kodiak Sciences Inc. Conjugués polymères zwittérioniques de butyrylcholinestérase
AR104847A1 (es) 2015-06-17 2017-08-16 Lilly Co Eli Formulación de anticuerpo anti-cgrp
WO2017015198A1 (fr) * 2015-07-17 2017-01-26 Coherus Biosciences, Inc. Formulations aqueuses stables de natalizumab
US10484453B2 (en) * 2015-07-29 2019-11-19 Xerox Corporation System and method for printing documents using print hardware and automatic context inference
AU2016381964B2 (en) 2015-12-30 2024-02-15 Kodiak Sciences Inc. Antibodies and conjugates thereof
EP3402465B1 (fr) 2016-01-13 2024-03-13 Genmab A/S Formulation pour anticorps et son conjugué pharmacologique
WO2017137570A1 (fr) 2016-02-10 2017-08-17 Becton Dickinson France Procédé pour évaluer la stabilité de formulation à base de protéine
WO2018091729A2 (fr) 2016-11-21 2018-05-24 Zaklady Farmaceutyczne Polpharma Sa Formulations pharmaceutiques aqueuses
CA3060581A1 (fr) 2017-05-02 2018-11-08 Merck Sharp & Dohme Corp. Formulations d'anticorps anti-lag3 etco-formulations d'anticorps anti-lag3 et d'anticorps anti-pd-1
JOP20190260A1 (ar) 2017-05-02 2019-10-31 Merck Sharp & Dohme صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
ES2938608T3 (es) * 2017-09-20 2023-04-13 Tillotts Pharma Ag Método para preparar una forma farmacéutica sólida que comprende anticuerpos mediante granulación en húmedo, extrusión y esferonización
KR20230130153A (ko) 2017-12-06 2023-09-11 머크 샤프 앤드 돔 엘엘씨 스트렙토코쿠스 뉴모니아에 폴리사카라이드-단백질 접합체를 포함하는 조성물 및 그의 사용 방법
US20190194277A1 (en) * 2017-12-08 2019-06-27 Argenx Bvba Use of fcrn antagonists for treatment of generalized myasthenia gravis
WO2019147824A1 (fr) 2018-01-26 2019-08-01 Progenity, Inc. Traitement d'une maladie du tractus gastro-intestinal avec un inhibiteur de pde4
US11426446B2 (en) 2018-03-08 2022-08-30 Coherus Biosciences, Inc. Stable aqueous formulations of aflibercept
EP3761953A1 (fr) 2018-03-08 2021-01-13 Coherus Biosciences, Inc. Formulations aqueuses stables d'aflibercept
SG11202009872YA (en) * 2018-04-10 2020-11-27 Dr Reddys Laboratories Ltd Stable antibody formulation
WO2019246317A1 (fr) 2018-06-20 2019-12-26 Progenity, Inc. Traitement d'une maladie ou d'un état dans un tissu provenant de l'endoderme
WO2019246273A1 (fr) 2018-06-20 2019-12-26 Progenity, Inc. Traitement d'une maladie du tractus gastro-intestinal avec un jak ou un autre inhibiteur de kinase
EP3810268A1 (fr) 2018-06-20 2021-04-28 Progenity, Inc. Traitement d'une maladie du tractus gastro-intestinal avec un inhibiteur d'il-12/il-23
WO2019246455A1 (fr) 2018-06-20 2019-12-26 Progenity, Inc. Traitement d'une maladie du tractus gastro-intestinal par un inhibiteur de l'intégrine
US20230041197A1 (en) 2018-06-20 2023-02-09 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
EP3810095A1 (fr) 2018-06-20 2021-04-28 Progenity, Inc. Traitement d'une maladie du tractus gastro-intestinal avec un inhibiteur du tnf
CN112566652A (zh) 2018-06-25 2021-03-26 Jcr制药股份有限公司 含有蛋白的水性液体制剂
MX2021005905A (es) 2018-11-20 2021-06-23 Janssen Biotech Inc Metodo seguro y eficaz para tratar la psoriasis con el anticuerpo especifico anti-il-23.
US20220296695A1 (en) 2018-12-19 2022-09-22 Merck Sharp & Dohme Corp. Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
TWI827732B (zh) * 2018-12-24 2024-01-01 大陸商遠大賽威信生命科學（南京）有限公司 用於治療b型肝炎的藥物製劑及其製備方法和用途
BR112021023295A2 (pt) 2019-05-23 2022-02-08 Janssen Biotech Inc Método de tratamento de doença inflamatória intestinal com uma terapia de combinação de anticorpos para il-23 e tnf-alfa
MA56102A (fr) * 2019-06-07 2022-04-13 Argenx Bvba Formulations pharmaceutique d'inhibiteurs de fcrn appropriées pour une administration par voie sous-cutanée
AU2020291508A1 (en) * 2019-06-11 2022-01-06 Macrogenics, Inc. Pharmaceutical formulations of bi-specific diabodies and use of the same
WO2021050687A1 (fr) 2019-09-10 2021-03-18 Coherus Biosciences, Inc. Formulations aqueuses stables d'aflibercept
EP4041312A4 (fr) 2019-10-10 2023-12-20 Kodiak Sciences Inc. Procédés de traitement d'un trouble oculaire
EP4079325A1 (fr) * 2019-12-16 2022-10-26 Nipro Corporation Agent inhibiteur d'agrégation, et composition médicale et dispositif médical le comprenant
JP2023512446A (ja) * 2020-01-13 2023-03-27 アプティーボ リサーチ アンド デベロップメント エルエルシー 治療的タンパク質の薬物送達システム構成要素への吸着を防ぐ方法および組成物
AU2021213153A1 (en) * 2020-01-29 2022-08-04 Merck Sharp & Dohme Llc Methods of separating host cell lipases from an anti-LAG3 antibody production

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2560155C2 (de) * 1974-03-08 1984-04-26 Teijin Ltd., Osaka Humanimmunglobulin-Derivat
US4362661A (en) * 1979-08-09 1982-12-07 Teijin Limited Immunoglobulin composition having a high monomer content, and process for production thereof
US4597966A (en) 1985-01-09 1986-07-01 Ortho Diagnostic Systems, Inc. Histidine stabilized immunoglobulin and method of preparation
US5981485A (en) 1997-07-14 1999-11-09 Genentech, Inc. Human growth hormone aqueous formulation
JPH03504499A (ja) * 1988-05-27 1991-10-03 セントカー・インコーポレーテツド 抗体試薬のための配合物
US5945098A (en) * 1990-02-01 1999-08-31 Baxter International Inc. Stable intravenously-administrable immune globulin preparation
US5840299A (en) 1994-01-25 1998-11-24 Athena Neurosciences, Inc. Humanized antibodies against leukocyte adhesion molecule VLA-4
US7435802B2 (en) 1994-01-25 2008-10-14 Elan Pharaceuticals, Inc. Humanized anti-VLA4 immunoglobulins
IL122910A (en) * 1995-07-27 2002-05-23 Genentech Inc Stable isotonic protein formulation that has undergone lyophilization
GB9610992D0 (en) 1996-05-24 1996-07-31 Glaxo Group Ltd Concentrated antibody preparation
EP0852951A1 (fr) 1996-11-19 1998-07-15 Roche Diagnostics GmbH Compositions pharmaceutiques stables, lyophilisées d'anticorps monoclonaux ou polyclonaux
ATE230277T1 (de) 1997-06-13 2003-01-15 Genentech Inc Stabilisierte antikörperformulierung
DE19912637A1 (de) 1999-03-20 2000-09-21 Aventis Cropscience Gmbh 2,4-Diamino-1,3,5-triazine, Verfahren zur Herstellung und Verwendung als Herbizide und Pflanzenwachstumsregulatoren
US6914128B1 (en) * 1999-03-25 2005-07-05 Abbott Gmbh & Co. Kg Human antibodies that bind human IL-12 and methods for producing
BR0009323A (pt) 1999-03-25 2002-01-08 Knoll Gmbh Anticorpos humanos que ligam a il-12 humana e métodos para a produção
DE10013029A1 (de) 2000-03-17 2001-09-20 Roehm Gmbh Mehrschichtige Arzneiform für die Colonfreigabe
US7288390B2 (en) * 2000-08-07 2007-10-30 Centocor, Inc. Anti-dual integrin antibodies, compositions, methods and uses
US6897205B2 (en) * 2001-01-31 2005-05-24 Roehm Gmbh & Co. Kg Multi-particulate form of medicament, comprising at least two differently coated forms of pellet
DE10133394A1 (de) * 2001-07-13 2003-01-30 Merck Patent Gmbh Flüssige Formulierung enthaltend Cetuximab
JP4317010B2 (ja) 2001-07-25 2009-08-19 ピーディーエル バイオファーマ，インコーポレイティド ＩｇＧ抗体の安定な凍結乾燥医薬製剤
EP3578168A1 (fr) 2002-02-14 2019-12-11 Chugai Seiyaku Kabushiki Kaisha Formulation de solutions contenant des anticorps comprenant un sucre comme stabilisant
RU2359697C2 (ru) * 2002-02-25 2009-06-27 Элан Фармасьютикалз, Инк. Введение средств для лечения воспаления
US20040033228A1 (en) * 2002-08-16 2004-02-19 Hans-Juergen Krause Formulation of human antibodies for treating TNF-alpha associated disorders
SI3417875T1 (sl) * 2003-02-10 2021-01-29 Biogen Ma Inc. Formulacija imunoglobulina in metode za njegovo pripravo
US7807187B2 (en) 2003-05-13 2010-10-05 The University Of Massachusetts Endogenous adjuvant molecules and uses thereof
WO2005076843A2 (fr) 2004-02-06 2005-08-25 Elan Pharmaceuticals, Inc. Methodes et compositions de traitement de tumeurs et de maladie metastatique
MY162179A (en) 2004-04-01 2017-05-31 Elan Pharm Inc Steroid sparing agents and methods of using same
SI2170390T1 (sl) 2007-06-14 2019-02-28 Biogen Ma Inc. Oblike protitelesa natalizumab

Also Published As

Publication number Publication date
CA2515444C (fr) 2014-04-01
NO346070B1 (no) 2022-01-31
US20100021461A1 (en) 2010-01-28
US8900577B2 (en) 2014-12-02
UA82685C2 (uk) 2008-05-12
CY1123667T1 (el) 2022-03-24
US20050053598A1 (en) 2005-03-10
WO2004071439A2 (fr) 2004-08-26
EP2236154B1 (fr) 2018-05-30
HK1182021A1 (en) 2013-11-22
KR20050110628A (ko) 2005-11-23
CN1771053B (zh) 2012-10-03
JP2006517233A (ja) 2006-07-20
ZA200506159B (en) 2006-10-25
CY1120574T1 (el) 2019-07-10
JP4728948B2 (ja) 2011-07-20
HUE051878T2 (hu) 2021-03-29
DK3417875T3 (da) 2020-08-31
CN103040732B (zh) 2015-04-01
AR043144A1 (es) 2005-07-20
PT3417875T (pt) 2020-08-24
US20120328614A1 (en) 2012-12-27
CN1771053A (zh) 2006-05-10
RU2005128280A (ru) 2006-06-10
AU2004210679A1 (en) 2004-08-26
RU2358763C2 (ru) 2009-06-20
AU2010202254A1 (en) 2010-06-24
US10954303B2 (en) 2021-03-23
US8815236B2 (en) 2014-08-26
TWI367766B (en) 2012-07-11
UY28184A1 (es) 2004-09-30
TR201808801T4 (tr) 2018-07-23
DK2236154T3 (en) 2018-06-25
PE20050190A1 (es) 2005-03-21
TW200505478A (en) 2005-02-16
NO20054164L (no) 2005-09-07
EP1592440A4 (fr) 2007-07-11
EP2236154A1 (fr) 2010-10-06
CN103040732A (zh) 2013-04-17
US20210292419A1 (en) 2021-09-23
EP3417875A1 (fr) 2018-12-26
SI2236154T1 (en) 2018-08-31
WO2004071439A3 (fr) 2005-07-07
US20180194843A1 (en) 2018-07-12
CA2515444A1 (fr) 2004-08-26
PT2236154T (pt) 2018-06-26
JP2014028831A (ja) 2014-02-13
EP3417875B1 (fr) 2020-06-17
CL2004000224A1 (es) 2005-01-21
MY162623A (en) 2017-06-30
US20130071386A1 (en) 2013-03-21
IL170008A (en) 2015-05-31
ES2819011T3 (es) 2021-04-14
US8349321B2 (en) 2013-01-08
AU2010202254B2 (en) 2012-02-23
US20150044206A1 (en) 2015-02-12
EP3777880A1 (fr) 2021-02-17
EP1592440A2 (fr) 2005-11-09
SI3417875T1 (sl) 2021-01-29
MXPA05008409A (es) 2005-10-05
JP2011088913A (ja) 2011-05-06

Similar Documents

Publication Publication Date Title
US20210292419A1 (en) Immunoglobulin formulation and method of preparation thereof
ES2676544T3 (es) Formulación de inmunoglobulina y procedimiento de preparación de la misma
AU2006211184B2 (en) Anti a beta antibody formulation
KR20100038100A (ko) 동결건조된 면역글로불린 제형 및 그의 제조 방법
AU2012202845B2 (en) Immunoglobulin formulation and method of preparation thereof
CA3235650A1 (fr) Formulations aqueuses d'un anticorps anti-cd22 et leurs utilisations
KR20240100493A (ko) 항-cd22 항체의 수성 제제 및 이의 용도

Legal Events

Date Code Title Description
TA4A Addition of inventor(s)
PC4A Assignment and transfer of rights

Owner name: BIOGEN IDEC INTERNATIONAL HOLDING LTD., HAMILT, BM

Free format text: FORMER OWNER: ELAN PHARMACEUTICALS, INC., CAMBRIDGE, MA, US

Effective date: 20141030

Owner name: BIOGEN IDEC MA INC., CAMBRIDGE, MASSACHUSETTS, US

Free format text: FORMER OWNER: BIOGEN IDEC INTERNATIONAL HOLDING LTD., HAMILTON HM EX, BM

Effective date: 20141030

TE4A Change of owner's address

Owner name: ELAN PHARMACEUTICALS, INC., CAMBRIDGE, MA, US

Effective date: 20141030

FC9A Refused patent application