SK287331B6 - Liečivo na liečenie zápalových a obštrukčných ochorení dýchacích ciest - Google Patents

Liečivo na liečenie zápalových a obštrukčných ochorení dýchacích ciest Download PDF

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Publication number
SK287331B6
SK287331B6 SK650-2003A SK6502003A SK287331B6 SK 287331 B6 SK287331 B6 SK 287331B6 SK 6502003 A SK6502003 A SK 6502003A SK 287331 B6 SK287331 B6 SK 287331B6
Authority
SK
Slovakia
Prior art keywords
medicament according
parts
medicament
carbon atoms
dispersion
Prior art date
Application number
SK650-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK6502003A3 (en
Inventor
Bernard Cuenoud
Robin Alec Fairhurst
Nicholas Lowther
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SK6502003A3 publication Critical patent/SK6502003A3/sk
Publication of SK287331B6 publication Critical patent/SK287331B6/sk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
SK650-2003A 2000-12-04 2001-12-03 Liečivo na liečenie zápalových a obštrukčných ochorení dýchacích ciest SK287331B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0029562.6A GB0029562D0 (en) 2000-12-04 2000-12-04 Organic compounds
PCT/EP2001/014122 WO2002045703A2 (fr) 2000-12-04 2001-12-03 Composes organiques

Publications (2)

Publication Number Publication Date
SK6502003A3 SK6502003A3 (en) 2003-12-02
SK287331B6 true SK287331B6 (sk) 2010-07-07

Family

ID=9904414

Family Applications (1)

Application Number Title Priority Date Filing Date
SK650-2003A SK287331B6 (sk) 2000-12-04 2001-12-03 Liečivo na liečenie zápalových a obštrukčných ochorení dýchacích ciest

Country Status (28)

Country Link
US (5) US6800643B2 (fr)
EP (2) EP1341542B1 (fr)
JP (2) JP2004514739A (fr)
KR (1) KR100523541B1 (fr)
CN (1) CN1212119C (fr)
AT (1) ATE361077T1 (fr)
AU (2) AU2002217082B2 (fr)
BR (1) BRPI0115910B8 (fr)
CA (1) CA2427282C (fr)
CY (1) CY1106727T1 (fr)
CZ (1) CZ304294B6 (fr)
DE (1) DE60128258T2 (fr)
DK (1) DK1341542T3 (fr)
EC (1) ECSP034620A (fr)
ES (1) ES2284732T3 (fr)
GB (1) GB0029562D0 (fr)
HK (1) HK1059564A1 (fr)
HU (1) HU229552B1 (fr)
IL (2) IL155709A0 (fr)
MX (1) MXPA03004976A (fr)
NO (1) NO325692B1 (fr)
NZ (1) NZ525731A (fr)
PL (1) PL204002B1 (fr)
PT (1) PT1341542E (fr)
RU (1) RU2292890C2 (fr)
SK (1) SK287331B6 (fr)
WO (1) WO2002045703A2 (fr)
ZA (1) ZA200303399B (fr)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
AR028948A1 (es) 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
GB0029562D0 (en) * 2000-12-04 2001-01-17 Novartis Ag Organic compounds
EP1894591B1 (fr) 2002-03-20 2013-06-26 MannKind Corporation Cartouche pour un appareil d'inhalation
US20040146509A1 (en) * 2002-07-25 2004-07-29 Zhihe Li Methods for improvement of lung function using TGF-beta inhibitors
PA8578101A1 (es) 2002-08-13 2004-05-07 Warner Lambert Co Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz
US7250426B2 (en) * 2002-11-29 2007-07-31 Boehringer Ingelheim Pharma Gmbh & Co Kg Tiotropium-containing pharmaceutical combination for inhalation
PE20100399A1 (es) * 2003-04-02 2010-06-01 Novartis Ag Procedimiento para preparar oxi-(1h)-quinolin-2-onas 5-(alfa-haloacetil)-8-sustituidas
MXPA05010712A (es) * 2003-04-04 2005-12-15 Novartis Ag Derivados de quinolin-2-ona para el tratamiento de enfermedades de las vias respiratorias.
GB0307856D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Organic compounds
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
ES2543007T3 (es) 2004-08-23 2015-08-13 Mannkind Corporation Micropartículas que comprenden sales de dicetopiperazina para la administración de fármacos
KR100666220B1 (ko) * 2005-01-31 2007-01-09 영남대학교 산학협력단 구내염 치료용 분사제 조성물
US20090298802A1 (en) * 2005-03-30 2009-12-03 Sequeira Joel A Pharmaceutical Compositions
GB0511066D0 (en) * 2005-05-31 2005-07-06 Novartis Ag Organic compounds
GB0511065D0 (en) * 2005-05-31 2005-07-06 Novartis Ag Organic compounds
TW200738634A (en) 2005-08-02 2007-10-16 Astrazeneca Ab New salt
TW200744612A (en) * 2005-08-26 2007-12-16 Astrazeneca Ab New combination
IN2014DN09128A (fr) 2005-09-14 2015-07-10 Mannkind Corp
GB0523655D0 (en) * 2005-11-21 2005-12-28 Novartis Ag Organic compounds
GB0523656D0 (en) * 2005-11-21 2005-12-28 Novartis Ag Organic compounds
WO2007075800A2 (fr) * 2005-12-20 2007-07-05 Tika Läkemedel Ab Méthodes et systèmes d'administration de corticostéroïdes
US8039431B2 (en) 2006-02-22 2011-10-18 Mannkind Corporation Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
US20070225233A1 (en) * 2006-03-27 2007-09-27 Tsu-Fuh Yeh Reducing the risk of chronic lung disease in infants
ES2396987T3 (es) 2006-06-30 2013-03-01 Novartis Ag Derivados de quinolina y sus composiciones farmacéuticas
EP1878722A1 (fr) * 2006-07-13 2008-01-16 Novartis AG Dérivés de quinolinone et leur compositions pharmaceutiques
EP2534957B1 (fr) 2007-12-14 2015-05-27 AeroDesigns, Inc Administration de produits sous forme d'aérosols
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP3281663B8 (fr) 2008-06-13 2022-09-21 MannKind Corporation Inhalateur de poudre sèche alimenté par la respiration pour l'administration de médicaments
WO2009155581A1 (fr) 2008-06-20 2009-12-23 Mannkind Corporation Appareil interactif pour l’établissement en temps réel d’un profil des efforts d’inhalation
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
JP5823383B2 (ja) 2009-05-29 2015-11-25 パール セラピューティクス，インコーポレイテッド 長時間作用性のムスカリン拮抗剤および長時間作用性のβ２アドレナリン受容体作動剤を肺送達するための組成物ならびに関連の方法および系
WO2010144789A2 (fr) 2009-06-12 2010-12-16 Mannkind Corporation Microparticules de dicétopipérazine avec des surfaces spécifiques définies
KR100940388B1 (ko) * 2009-07-01 2010-02-02 유병덕 스크류탈수기 및 이를 포함하는 유기성폐기물 건조장치
WO2011056889A1 (fr) 2009-11-03 2011-05-12 Mannkind Corporation Appareil et méthode de simulation d'efforts d'inhalation
JP6385673B2 (ja) 2010-06-21 2018-09-05 マンカインド コーポレイション 乾燥粉末薬物送達システム
BR112013001119A2 (pt) * 2010-07-16 2016-05-24 Cipla Ltd composição farmacêutica, processo para fabricar uma composição farmacêutica, uso de r(+)budesonida e um broncodilatador, e método de profilaxia ou tratamento de uma doença respiratória, inflamatória ou obstrutiva das vias aéreas
KR20180028563A (ko) * 2010-10-12 2018-03-16 시플라 리미티드 약학 조성물
DK2694402T3 (en) 2011-04-01 2017-07-03 Mannkind Corp BLISTER PACKAGE FOR PHARMACEUTICAL CYLINDER AMPULS
WO2012174472A1 (fr) 2011-06-17 2012-12-20 Mannkind Corporation Microparticules de dicétopipérazine de capacité élevée
CN102247380A (zh) * 2011-08-19 2011-11-23 北京阜康仁生物制药科技有限公司 一种以布地奈德与茚达特罗为活性成分的复方制剂
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
WO2013132514A2 (fr) * 2012-03-09 2013-09-12 Rao Davuluri Ramamohan Nouveau procédé de préparation de (r)-5-[2-[(5, 6-diéthyl-2, 3-dihydro-1h-indèn-2-yl) amino]-1-hydroxyéthyl]-8-hydroxy quinoléin-2(1h)-one
WO2014008639A1 (fr) * 2012-07-11 2014-01-16 上海威智医药科技有限公司 Procédé de préparation d'indacatérol
MX354163B (es) 2012-07-12 2018-02-15 Mannkind Corp Sistemas y métodos de suministro de fármaco en polvo seco.
WO2014044288A1 (fr) * 2012-09-21 2014-03-27 Crystal Pharma Sa Procédés de préparation d'indacatérol et de ses sels pharmaceutiquement acceptables
EP2911690A1 (fr) 2012-10-26 2015-09-02 MannKind Corporation Compositions et procédés de vaccin antigrippal inhalable
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MX2016000739A (es) 2013-07-18 2017-04-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
EP3030294B1 (fr) 2013-08-05 2020-10-07 MannKind Corporation Appareil d'insufflation
WO2015148905A1 (fr) 2014-03-28 2015-10-01 Mannkind Corporation Utilisation d'insuline à action ultrarapide
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
ITUB20153978A1 (it) * 2015-09-28 2017-03-28 Laboratorio Chimico Int S P A Procedimento per la preparazione di derivati di indanammina e di nuovi intermedi di sintesi.
CN107868045A (zh) * 2016-09-28 2018-04-03 四川海思科制药有限公司 一种茚达特罗中间体的制备方法
CN106831445B (zh) * 2016-11-22 2019-01-22 斯芬克司药物研发（天津）股份有限公司 一种茚基胺化合物的制备方法
CN110229078A (zh) * 2019-05-22 2019-09-13 博诺康源(北京)药业科技有限公司 一种茚达特罗起始原料开环杂质的制备
CN114751857A (zh) * 2022-04-29 2022-07-15 梯尔希（南京）药物研发有限公司 一种茚达特罗杂质的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4607028A (en) * 1983-08-18 1986-08-19 Ciba-Geigy Corporation Novel carboxylic acid esters
WO1993018007A1 (fr) * 1992-03-13 1993-09-16 Tokyo Tanabe Company Limited Nouveau derive de carbostyrile
GB9405019D0 (en) * 1994-03-15 1994-04-27 Smithkline Beecham Plc Novel compounds
GB9501286D0 (en) * 1995-01-24 1995-03-15 Ciba Geigy Ag Pharmaceutical compositions and preparations thereof
DE69630639T2 (de) * 1995-08-16 2004-09-16 Huntington Medical Research Institutes, Pasadena Rhodamin 123 Zusammensetzungen für Behandlung von Prostatakrebs
GB9603237D0 (en) * 1996-02-16 1996-04-17 Sandoz Ltd Organic compounds
TW375604B (en) 1996-02-19 1999-12-01 Kissei Pharmaceutical 3,4-di-substituting phenyl-ethanolamine-tetrahydronaphthyl carboxylic amide derivatives
GB9610122D0 (en) * 1996-05-15 1996-07-24 Reckitt & Colmann Prod Ltd Organic compositions
KR100335169B1 (ko) * 1997-07-03 2002-05-04 야마모토 카즈모토 포화 고리를 갖는 신규한 트리시클릭 화합물 및 이를포함하는 의약 조성물
GB9902689D0 (en) * 1999-02-08 1999-03-31 Novartis Ag Organic compounds
GB9913083D0 (en) * 1999-06-04 1999-08-04 Novartis Ag Organic compounds
US6448239B1 (en) 1999-06-03 2002-09-10 Trustees Of Princeton University Peroxynitrite decomposition catalysts and methods of use thereof
US6664235B1 (en) * 1999-08-20 2003-12-16 Riken Medicaments comprising sialic acid derivatives as active ingredients
US20020076382A1 (en) * 2000-08-04 2002-06-20 Kaplan Leonard W. Formulations of mometasone and a bronchodilator for pulmonary administration
GB0029562D0 (en) * 2000-12-04 2001-01-17 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
AU1708202A (en) 2002-06-18
HUP0302571A2 (hu) 2003-11-28
PT1341542E (pt) 2007-08-01
WO2002045703A2 (fr) 2002-06-13
US20040038951A1 (en) 2004-02-26
US20120108555A1 (en) 2012-05-03
NO325692B1 (no) 2008-07-07
US7622484B2 (en) 2009-11-24
DE60128258T2 (de) 2007-12-27
HU229552B1 (en) 2014-01-28
JP2007302684A (ja) 2007-11-22
ES2284732T3 (es) 2007-11-16
JP2004514739A (ja) 2004-05-20
HK1059564A1 (en) 2004-07-09
ZA200303399B (en) 2004-04-23
CN1212119C (zh) 2005-07-27
ATE361077T1 (de) 2007-05-15
DK1341542T3 (da) 2007-09-03
KR100523541B1 (ko) 2005-10-25
HUP0302571A3 (en) 2005-05-30
US20060052352A1 (en) 2006-03-09
NZ525731A (en) 2004-11-26
ECSP034620A (es) 2003-06-25
PL204002B1 (pl) 2009-12-31
US7008951B2 (en) 2006-03-07
CZ304294B6 (cs) 2014-02-19
US6800643B2 (en) 2004-10-05
CN1477963A (zh) 2004-02-25
BRPI0115910B1 (pt) 2019-12-31
BRPI0115910B8 (pt) 2021-05-25
EP1341542A2 (fr) 2003-09-10
MXPA03004976A (es) 2003-09-05
NO20032510D0 (no) 2003-06-03
KR20030048065A (ko) 2003-06-18
GB0029562D0 (en) 2001-01-17
SK6502003A3 (en) 2003-12-02
CA2427282A1 (fr) 2002-06-13
IL155709A (en) 2008-11-26
CY1106727T1 (el) 2012-05-23
US20100068288A1 (en) 2010-03-18
IL155709A0 (en) 2003-11-23
WO2002045703A3 (fr) 2003-03-13
EP1772142A3 (fr) 2011-09-14
PL362443A1 (en) 2004-11-02
EP1341542B1 (fr) 2007-05-02
CA2427282C (fr) 2010-10-19
RU2003119549A (ru) 2005-02-10
EP1772142A2 (fr) 2007-04-11
BR0115910A (pt) 2004-01-20
DE60128258D1 (de) 2007-06-14
US20050009795A1 (en) 2005-01-13
RU2292890C2 (ru) 2007-02-10
AU2002217082B2 (en) 2005-04-07
NO20032510L (no) 2003-06-03
CZ20031537A3 (cs) 2003-10-15

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