SK287014B6 - Živá vakcína, farmaceutický prostriedok s jej obsahom, jej použitie, spôsob oslabenia pestivírusov a spôsob odlíšenia pestivírusom infikovaných zvierat od očkovaných - Google Patents

Živá vakcína, farmaceutický prostriedok s jej obsahom, jej použitie, spôsob oslabenia pestivírusov a spôsob odlíšenia pestivírusom infikovaných zvierat od očkovaných Download PDF

Info

Publication number
SK287014B6
SK287014B6 SK1823-2000A SK18232000A SK287014B6 SK 287014 B6 SK287014 B6 SK 287014B6 SK 18232000 A SK18232000 A SK 18232000A SK 287014 B6 SK287014 B6 SK 287014B6
Authority
SK
Slovakia
Prior art keywords
pestivirus
glycoprotein
animal
lys
leu
Prior art date
Application number
SK1823-2000A
Other languages
English (en)
Slovak (sk)
Other versions
SK18232000A3 (sk
Inventor
Gregor Meyers
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of SK18232000A3 publication Critical patent/SK18232000A3/sk
Publication of SK287014B6 publication Critical patent/SK287014B6/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases RNAses, DNAses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13Tumour cells, irrespective of tissue of origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24311Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24311Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24361Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SK1823-2000A 1998-06-05 1999-05-26 Živá vakcína, farmaceutický prostriedok s jej obsahom, jej použitie, spôsob oslabenia pestivírusov a spôsob odlíšenia pestivírusom infikovaných zvierat od očkovaných SK287014B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98110356A EP0965639A1 (en) 1998-06-05 1998-06-05 Attenuated pestiviruses
PCT/EP1999/003642 WO1999064604A2 (en) 1998-06-05 1999-05-26 Attenuated pestiviruses

Publications (2)

Publication Number Publication Date
SK18232000A3 SK18232000A3 (sk) 2001-05-10
SK287014B6 true SK287014B6 (sk) 2009-09-07

Family

ID=8232074

Family Applications (3)

Application Number Title Priority Date Filing Date
SK50018-2009A SK287625B6 (sk) 1998-06-05 1999-05-26 Oslabený pestivírus, nukleová kyselina, farmaceutický prostriedok s ich obsahom a ich použitie
SK1823-2000A SK287014B6 (sk) 1998-06-05 1999-05-26 Živá vakcína, farmaceutický prostriedok s jej obsahom, jej použitie, spôsob oslabenia pestivírusov a spôsob odlíšenia pestivírusom infikovaných zvierat od očkovaných
SK50019-2009A SK287626B6 (sk) 1998-06-05 1999-05-26 Spôsob detegovateľného značenia pestivírusov

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SK50018-2009A SK287625B6 (sk) 1998-06-05 1999-05-26 Oslabený pestivírus, nukleová kyselina, farmaceutický prostriedok s ich obsahom a ich použitie

Family Applications After (1)

Application Number Title Priority Date Filing Date
SK50019-2009A SK287626B6 (sk) 1998-06-05 1999-05-26 Spôsob detegovateľného značenia pestivírusov

Country Status (23)

Country Link
EP (5) EP0965639A1 (xx)
JP (3) JP4632540B2 (xx)
KR (1) KR100637940B1 (xx)
CN (2) CN100374563C (xx)
AR (3) AR020084A1 (xx)
AT (3) ATE316380T1 (xx)
AU (1) AU769823C (xx)
BR (2) BRPI9917787B1 (xx)
CA (1) CA2330241C (xx)
CO (1) CO5050392A1 (xx)
CZ (3) CZ301569B6 (xx)
DE (3) DE69929544T2 (xx)
DK (3) DK1203813T3 (xx)
ES (3) ES2257476T3 (xx)
HU (3) HU228469B1 (xx)
NZ (1) NZ509228A (xx)
PE (1) PE20000552A1 (xx)
PL (2) PL202161B1 (xx)
PT (2) PT1203813E (xx)
SI (3) SI1203813T1 (xx)
SK (3) SK287625B6 (xx)
TR (3) TR200003622T2 (xx)
WO (1) WO1999064604A2 (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179473B2 (en) 1998-06-05 2007-02-20 Boehringer Ingelheim Vetmedica Gmbh Attenuated pestiviruses
EP1104676A1 (en) * 1999-11-30 2001-06-06 Boehringer Ingelheim Vetmedica Gmbh Safe attenuated bovine viral diarrhea viruses for use in pregnant cows
ES2261329T3 (es) * 2000-04-21 2006-11-16 Akzo Nobel N.V. Mutantes de pestivirus y vacunas que los contienen.
US7135561B2 (en) 2001-09-06 2006-11-14 Boehringer Ingelheim Vetmedica Gmbh Infectious bovine viral diarrhea virus clone
UY29915A1 (es) 2005-11-15 2007-06-29 Boehringer Ingelheim Vetmed Vacuna combinada que comprende un virus atenuado de la diarrea viral bovina
AR069087A1 (es) 2007-10-29 2009-12-30 Boehringer Ingelheim Vetmed Cepa bacteriana de m. bovis atenuada avirulenta obtenida por pases, vacuna de micoplasma boris y metodos de uso de la misma
UY31930A (es) 2008-06-25 2010-01-29 Boheringer Ingelheim Pharma Kg Pestivirus atenuados recombinantes, en particular a csfv, bvdv o bdv atenuado recombinante
EP2362780B1 (en) 2008-10-31 2019-12-25 Boehringer Ingelheim Animal Health USA Inc. Use of various antigens including antigens from mycoplasma bovis in multivalent vaccine composition
US8846054B2 (en) 2009-01-09 2014-09-30 Boehringer Ingelheim Vetmedica, Inc. Method of treating pregnant cows and/or heifers
UY32570A (es) 2009-04-24 2010-11-30 Boehringer Ingelheim Vetmed Vacuna viva modificada de mycoplasma bovis mejorada
CN101915837B (zh) * 2010-07-28 2013-07-03 中国兽医药品监察所 一种猪瘟兔化弱毒活疫苗效力检验方法
ES2606605T3 (es) 2010-09-21 2017-03-24 Intervet International B.V. Vacuna para el BVDV
CN103882051B (zh) * 2014-03-20 2016-04-06 北京市农林科学院 一种检测猪瘟病毒抗体的elisa方法及检测试剂盒
WO2020211801A1 (en) * 2019-04-18 2020-10-22 Boehringer Ingelheim Vetmedica (China) Co., Ltd. Recombinant classical swine fever virus

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3752182T2 (de) * 1986-01-27 1998-08-06 Syntro Corp Abgeschwächte herpesviren, herpesviren, die eine für aminosäuresequenzen kodierende fremd-dns enthalten, sowie impfstoffe, die diese enthalten

Also Published As

Publication number Publication date
JP5755265B2 (ja) 2015-07-29
TR200103664T2 (tr) 2002-06-21
HU228468B1 (en) 2013-03-28
SI1203813T1 (sl) 2006-06-30
EP1084251A2 (en) 2001-03-21
HU228471B1 (en) 2013-03-28
PT1203813E (pt) 2006-06-30
DE69929544D1 (de) 2006-04-13
JP2010259445A (ja) 2010-11-18
CA2330241C (en) 2010-09-21
HUP0102707A3 (en) 2008-04-28
ATE311193T1 (de) 2005-12-15
SI1084251T1 (xx) 2005-08-31
BR9911619A (pt) 2001-10-02
JP4632540B2 (ja) 2011-02-16
CA2330241A1 (en) 1999-12-16
BR9911619B1 (pt) 2013-11-12
WO1999064604A2 (en) 1999-12-16
EP1614423A3 (en) 2008-01-30
PL202161B1 (pl) 2009-06-30
DE69928700T2 (de) 2006-06-22
DE69929544T2 (de) 2006-07-20
JP2002517250A (ja) 2002-06-18
CN100374563C (zh) 2008-03-12
WO1999064604A3 (en) 2000-01-27
BRPI9917787B1 (pt) 2016-09-06
SK287625B6 (sk) 2011-04-05
AR020084A1 (es) 2002-04-10
EP1614423A2 (en) 2006-01-11
DK1203812T3 (da) 2006-04-10
KR20010071406A (ko) 2001-07-28
CN101085346A (zh) 2007-12-12
CZ20004533A3 (cs) 2001-07-11
AU4369299A (en) 1999-12-30
KR100637940B1 (ko) 2006-10-23
JP5247770B2 (ja) 2013-07-24
CN1304452A (zh) 2001-07-18
AU769823B2 (en) 2004-02-05
SK18232000A3 (sk) 2001-05-10
EP0965639A1 (en) 1999-12-22
ATE286131T1 (de) 2005-01-15
SK287626B6 (sk) 2011-04-05
SI1203812T1 (sl) 2006-04-30
JP2013099357A (ja) 2013-05-23
EP1203812B1 (en) 2005-11-30
TR200003622T2 (tr) 2001-06-21
EP1203813A3 (en) 2004-02-04
NZ509228A (en) 2003-12-19
ES2235488T3 (es) 2005-07-01
AR071881A2 (es) 2010-07-21
ES2257476T3 (es) 2006-08-01
PT1084251E (pt) 2005-03-31
DE69928700D1 (de) 2006-01-05
ATE316380T1 (de) 2006-02-15
CO5050392A1 (es) 2001-06-27
EP1084251B1 (en) 2004-12-29
AR071880A2 (es) 2010-07-21
CZ301569B6 (cs) 2010-04-21
EP1203813A2 (en) 2002-05-08
HUP0102707A2 (hu) 2001-11-28
CZ301570B6 (cs) 2010-04-21
DK1084251T3 (da) 2005-04-11
DE69922953T2 (de) 2005-05-19
AU769823C (en) 2004-11-25
EP1203813B1 (en) 2006-01-25
DE69922953D1 (de) 2005-02-03
TR200103666T2 (tr) 2002-03-21
DK1203813T3 (da) 2006-05-22
CZ301494B6 (cs) 2010-03-24
ES2253457T3 (es) 2006-06-01
EP1203812A2 (en) 2002-05-08
PE20000552A1 (es) 2000-07-14
EP1203812A3 (en) 2004-02-04
HU228469B1 (en) 2013-03-28
PL348019A1 (en) 2002-05-06
PL202509B1 (pl) 2009-06-30

Similar Documents

Publication Publication Date Title
JP5755265B2 (ja) 弱毒化ペスチウイルス
US8895286B2 (en) Attenuated pestiviruses
US6610305B1 (en) Safe attenuated bovine viral diarrhea viruses for use in pregnant cows
MXPA00011971A (en) Attenuated pestiviruses

Legal Events

Date Code Title Description
MK4A Patent expired

Expiry date: 20190526