SK285461B6 - Izolovaný polypeptid KIM, modulátor tkanivovej regenerácie a nukleová kyselina, ktorá ho kóduje, spôsob prípravy polypeptidu a farmaceutická kompozícia obsahujúca polypeptid - Google Patents

Izolovaný polypeptid KIM, modulátor tkanivovej regenerácie a nukleová kyselina, ktorá ho kóduje, spôsob prípravy polypeptidu a farmaceutická kompozícia obsahujúca polypeptid Download PDF

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Publication number
SK285461B6
SK285461B6 SK1609-98A SK160998A SK285461B6 SK 285461 B6 SK285461 B6 SK 285461B6 SK 160998 A SK160998 A SK 160998A SK 285461 B6 SK285461 B6 SK 285461B6
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SK
Slovakia
Prior art keywords
kim
seq
thr
protein
antibody
Prior art date
Application number
SK1609-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK160998A3 (en
Inventor
Michele Sanicola-Nadel
Joseph V. Bonventre
Catherine A. Hession
Takaharu Ichimura
Henry Wei
Richard L. Cate
Original Assignee
Biogen Idec Ma Inc.
The General Hospital Corporation
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26690881&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK285461(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Idec Ma Inc., The General Hospital Corporation filed Critical Biogen Idec Ma Inc.
Publication of SK160998A3 publication Critical patent/SK160998A3/sk
Publication of SK285461B6 publication Critical patent/SK285461B6/sk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Optics & Photonics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Electrotherapy Devices (AREA)
SK1609-98A 1996-05-24 1997-05-23 Izolovaný polypeptid KIM, modulátor tkanivovej regenerácie a nukleová kyselina, ktorá ho kóduje, spôsob prípravy polypeptidu a farmaceutická kompozícia obsahujúca polypeptid SK285461B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1822896P 1996-05-24 1996-05-24
US2344296P 1996-08-23 1996-08-23
PCT/US1997/009303 WO1997044460A1 (en) 1996-05-24 1997-05-23 Modulators of tissue regeneration

Publications (2)

Publication Number Publication Date
SK160998A3 SK160998A3 (en) 1999-07-12
SK285461B6 true SK285461B6 (sk) 2007-02-01

Family

ID=26690881

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1609-98A SK285461B6 (sk) 1996-05-24 1997-05-23 Izolovaný polypeptid KIM, modulátor tkanivovej regenerácie a nukleová kyselina, ktorá ho kóduje, spôsob prípravy polypeptidu a farmaceutická kompozícia obsahujúca polypeptid

Country Status (27)

Country Link
US (4) US6664385B1 (ja)
EP (2) EP1655367A1 (ja)
JP (3) JP4602482B2 (ja)
CN (1) CN1147584C (ja)
AT (1) ATE318903T1 (ja)
AU (1) AU712289B2 (ja)
BG (1) BG64678B1 (ja)
BR (1) BR9709115A (ja)
CA (1) CA2257851C (ja)
CZ (1) CZ295936B6 (ja)
DE (1) DE69735364T3 (ja)
DK (1) DK0907735T5 (ja)
EA (1) EA004402B1 (ja)
EE (1) EE04817B1 (ja)
ES (1) ES2258793T5 (ja)
HK (1) HK1021746A1 (ja)
HU (1) HU226205B1 (ja)
IL (1) IL127162A (ja)
IS (1) IS2636B (ja)
NO (2) NO327597B1 (ja)
NZ (1) NZ336467A (ja)
PL (1) PL188826B1 (ja)
PT (1) PT907735E (ja)
SI (1) SI0907735T2 (ja)
SK (1) SK285461B6 (ja)
TR (1) TR199802421T2 (ja)
WO (1) WO1997044460A1 (ja)

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Publication number Publication date
EP0907735A1 (en) 1999-04-14
CZ295936B6 (cs) 2005-12-14
CZ381398A3 (cs) 1999-05-12
BG102967A (bg) 2000-05-31
PL330313A1 (en) 1999-05-10
ES2258793T5 (es) 2010-01-25
CN1223685A (zh) 1999-07-21
IL127162A (en) 2007-07-24
NO20090945L (no) 1999-01-25
BR9709115A (pt) 1999-08-03
PL188826B1 (pl) 2005-04-29
NZ336467A (en) 2000-10-27
DE69735364D1 (de) 2006-04-27
HU226205B1 (en) 2008-06-30
IS4902A (is) 1998-11-20
TR199802421T2 (xx) 1999-02-22
US6664385B1 (en) 2003-12-16
DK0907735T4 (da) 2009-12-21
EA199801044A1 (ru) 1999-04-29
PT907735E (pt) 2006-06-30
EP1655367A1 (en) 2006-05-10
DK0907735T5 (da) 2010-06-14
EA004402B1 (ru) 2004-04-29
DE69735364T2 (de) 2006-11-30
EP0907735B1 (en) 2006-03-01
US20050089868A1 (en) 2005-04-28
NO985427L (no) 1999-01-25
IS2636B (is) 2010-06-15
DE69735364T3 (de) 2010-05-06
EP0907735B2 (en) 2009-10-07
JP4602482B2 (ja) 2010-12-22
AU3567697A (en) 1997-12-09
CA2257851A1 (en) 1997-11-27
JP2009039111A (ja) 2009-02-26
WO1997044460A1 (en) 1997-11-27
SI0907735T2 (sl) 2010-01-29
EP0907735B9 (en) 2010-05-19
US20060286031A1 (en) 2006-12-21
EE04817B1 (et) 2007-04-16
SK160998A3 (en) 1999-07-12
HK1021746A1 (en) 2000-06-30
JP4316640B2 (ja) 2009-08-19
AU712289B2 (en) 1999-11-04
ATE318903T1 (de) 2006-03-15
CA2257851C (en) 2011-11-15
US20070141590A1 (en) 2007-06-21
DK0907735T3 (da) 2006-06-26
HUP9902770A3 (en) 2001-09-28
JP2001505761A (ja) 2001-05-08
CN1147584C (zh) 2004-04-28
NO985427D0 (no) 1998-11-20
JP2008067701A (ja) 2008-03-27
BG64678B1 (bg) 2005-11-30
EE9800409A (et) 1999-06-15
SI0907735T1 (sl) 2006-08-31
NO327597B1 (no) 2009-08-31
ES2258793T3 (es) 2006-09-01
HUP9902770A2 (hu) 1999-12-28
IL127162A0 (en) 1999-09-22

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