SK285121B6 - Bis(akridínkarboxamidový) alebo bis(fenazínkarboxamidový) derivát, spôsob prípravy, použitie a farmaceutické prostriedky - Google Patents

Bis(akridínkarboxamidový) alebo bis(fenazínkarboxamidový) derivát, spôsob prípravy, použitie a farmaceutické prostriedky Download PDF

Info

Publication number
SK285121B6
SK285121B6 SK504-99A SK50499A SK285121B6 SK 285121 B6 SK285121 B6 SK 285121B6 SK 50499 A SK50499 A SK 50499A SK 285121 B6 SK285121 B6 SK 285121B6
Authority
SK
Slovakia
Prior art keywords
bis
carboxamido
propyl
methylamine
arh
Prior art date
Application number
SK504-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK50499A3 (en
Inventor
William Alexander Denny
Swarnalatha Akuritaya Gamage
Julie Ann Spicer
Bruce Charles Baguley
Graeme John Finlay
Original Assignee
Xenova Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenova Limited filed Critical Xenova Limited
Publication of SK50499A3 publication Critical patent/SK50499A3/sk
Publication of SK285121B6 publication Critical patent/SK285121B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polishing Bodies And Polishing Tools (AREA)
  • Multicomponent Fibers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Liquid Crystal (AREA)
SK504-99A 1996-10-18 1997-10-17 Bis(akridínkarboxamidový) alebo bis(fenazínkarboxamidový) derivát, spôsob prípravy, použitie a farmaceutické prostriedky SK285121B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9621795.5A GB9621795D0 (en) 1996-10-18 1996-10-18 Pharmaceutical compounds
PCT/GB1997/002886 WO1998017650A1 (en) 1996-10-18 1997-10-17 Bis(acridinecarboxamide) and bis(phenazinecarboxamide) as antitumour agents

Publications (2)

Publication Number Publication Date
SK50499A3 SK50499A3 (en) 2000-05-16
SK285121B6 true SK285121B6 (sk) 2006-06-01

Family

ID=10801674

Family Applications (1)

Application Number Title Priority Date Filing Date
SK504-99A SK285121B6 (sk) 1996-10-18 1997-10-17 Bis(akridínkarboxamidový) alebo bis(fenazínkarboxamidový) derivát, spôsob prípravy, použitie a farmaceutické prostriedky

Country Status (30)

Country Link
US (1) US6114332A (da)
EP (1) EP0934278B1 (da)
JP (1) JP2001503399A (da)
KR (1) KR20000049252A (da)
CN (1) CN1116285C (da)
AT (1) ATE223381T1 (da)
AU (1) AU717724B2 (da)
BG (1) BG64555B1 (da)
BR (1) BR9711948A (da)
CA (1) CA2268411C (da)
CZ (1) CZ295302B6 (da)
DE (1) DE69715230T2 (da)
DK (1) DK0934278T3 (da)
ES (1) ES2183142T3 (da)
GB (2) GB9621795D0 (da)
HK (1) HK1018773A1 (da)
HU (1) HU221953B1 (da)
ID (1) ID22444A (da)
MY (1) MY122017A (da)
NO (1) NO313381B1 (da)
NZ (1) NZ335055A (da)
PL (1) PL193669B1 (da)
PT (1) PT934278E (da)
RO (1) RO120636B1 (da)
RU (1) RU2179972C2 (da)
SK (1) SK285121B6 (da)
TW (1) TW432060B (da)
UA (1) UA67729C2 (da)
WO (1) WO1998017650A1 (da)
ZA (2) ZA979328B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6974878B2 (en) 2001-03-21 2005-12-13 Symyx Technologies, Inc. Catalyst ligands, catalytic metal complexes and processes using same
EP1131283A1 (en) * 1999-09-10 2001-09-12 Symyx Technologies Catalyst ligands, catalytic metal complexes and processes using and methods of making same
WO2005063760A1 (en) * 2003-12-31 2005-07-14 Council Of Scientific & Industrial Research C-8 LINKED PYRROLO[2,1-c][1,4]BENZODIAZEPINE-ACRIDONE/ACRIDINE HYBRIDS
EP3086791A4 (en) * 2013-12-24 2017-06-14 University of Florida Research Foundation, Inc. Phenazine derivatives as antimicrobial agents
CN104961801B (zh) * 2015-07-13 2018-01-19 兰州大学 一种具有多靶点的抗菌多肽偶联物及其二聚物的合成和应用
CN106554321B (zh) * 2015-09-25 2019-05-28 陆源 一种吩嗪类物质、其制备方法及其应用
US20240279204A1 (en) * 2021-12-09 2024-08-22 Korea Institute Of Ocean Science & Technology Novel diphenazine compound, and use thereof for preventing or treating cancer or neuroinflammatory diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201084A (en) * 1982-06-25 1985-10-11 New Zealand Dev Finance 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such
JPS61112061A (ja) * 1984-08-16 1986-05-30 デベロツプメント フアイナンス コ−ポレ−シヨン オブニユ−ジ−ランド 新規なフエナジン誘導体
IT1293525B1 (it) * 1997-08-01 1999-03-01 Uni Degli Studi Camerino Bis-acridincarbossiammidi aventi attivita' antitumorale

Also Published As

Publication number Publication date
AU717724B2 (en) 2000-03-30
BG103329A (en) 2000-11-30
ZA979328B (en) 1998-07-06
GB9621795D0 (en) 1996-12-11
JP2001503399A (ja) 2001-03-13
EP0934278B1 (en) 2002-09-04
GB2334032B (en) 2000-11-08
US6114332A (en) 2000-09-05
TW432060B (en) 2001-05-01
GB9908192D0 (en) 1999-06-02
CZ127199A3 (cs) 1999-09-15
NZ335055A (en) 2000-09-29
CZ295302B6 (cs) 2005-07-13
DK0934278T3 (da) 2003-01-06
NO991833L (no) 1999-06-03
NO991833D0 (no) 1999-04-16
ES2183142T3 (es) 2003-03-16
BG64555B1 (bg) 2005-07-29
ATE223381T1 (de) 2002-09-15
BR9711948A (pt) 1999-08-24
DE69715230D1 (de) 2002-10-10
DE69715230T2 (de) 2009-09-17
CN1116285C (zh) 2003-07-30
PL193669B1 (pl) 2007-03-30
UA67729C2 (uk) 2004-07-15
RU2179972C2 (ru) 2002-02-27
KR20000049252A (ko) 2000-07-25
ZA979331B (en) 1998-05-21
CN1240430A (zh) 2000-01-05
HU221953B1 (hu) 2003-03-28
WO1998017650A1 (en) 1998-04-30
AU4713797A (en) 1998-05-15
NO313381B1 (no) 2002-09-23
RO120636B1 (ro) 2006-05-30
GB2334032A (en) 1999-08-11
PL332877A1 (en) 1999-10-25
CA2268411A1 (en) 1998-04-30
SK50499A3 (en) 2000-05-16
EP0934278A1 (en) 1999-08-11
PT934278E (pt) 2003-01-31
ID22444A (id) 1999-10-14
MY122017A (en) 2006-03-31
HK1018773A1 (en) 2000-01-07
HUP9902883A3 (en) 2001-01-29
CA2268411C (en) 2008-07-22

Similar Documents

Publication Publication Date Title
DE3719924A1 (de) 8-substituierte 2-aminotetraline
EP0980362B1 (de) Substituierte heterocyclen und deren verwendung in arzneimitteln
SK285121B6 (sk) Bis(akridínkarboxamidový) alebo bis(fenazínkarboxamidový) derivát, spôsob prípravy, použitie a farmaceutické prostriedky
Chen et al. Electron-deficient DNA intercalating agents as antitumor drugs: Aza analogs of the experimental clinical agent N-[2-(dimethylamino) ethyl] acridine-4-carboxamide
CA3160699A1 (en) Process for the preparation of lasmiditan and of a synthesis intermediate
EP0187509A2 (en) 9-Aminoalkylfluorenes
EP0934277B1 (en) Process for the preparation of n- 2-(dimethylamino)ethyl]acridine-4-carboxamide
JP6923112B2 (ja) フィロウイルスの細胞侵入阻害活性を有するビアリールスルフォンアミド誘導体
US3228976A (en) 1, 4-bis-(aminomethyl)-1-cyclohexene compounds
HU202506B (en) Process for producing benzoxazolone derivatives
CN113651767B (zh) 一种苯并异噁唑类杂环化合物及其制备方法和应用
US6919328B1 (en) Tricyclic compounds with NOS activity
JP3940791B2 (ja) 1,2−ベンゾイソチアゾリン−3−オン化合物の製造方法
CN102260187B (zh) 取代的氨甲酰基环己甲酸类化合物及其制法和用途
US4288437A (en) 2-[(Amino)-aryl-methylene]-benzo[b]thiophen-3(2H)-ones
DE102007049039A1 (de) Verfahren zur Herstellung von 8-Hydrazino-8-Aryl-Octanoylderivaten und deren Verwendung
CA2049770A1 (en) Production of diethanolamine derivatives and their intermediates
EP1115708A1 (de) Aminoalkyl-3,4-dihydrochinolin-derivate als no synthase inhibitoren
Prasad et al. One Pot Synthesis of Dibenzo [b, f][l, 4] Thiazepine-l l-(10H)-One
JPH04356451A (ja) ジエタノールアミン誘導体
PL108068B1 (pl) Sposob wytwarzania nowych pochodnych tiazolinylokemethod of producing new derivatives of thiazolinyloketobenzimidazole tobenzimidazolu