HK1018773A1 - Bis(acridinecarboxamide) and bis(phenazinecarboxamide) as antitumour agents - Google Patents

Bis(acridinecarboxamide) and bis(phenazinecarboxamide) as antitumour agents

Info

Publication number
HK1018773A1
HK1018773A1 HK99103666A HK99103666A HK1018773A1 HK 1018773 A1 HK1018773 A1 HK 1018773A1 HK 99103666 A HK99103666 A HK 99103666A HK 99103666 A HK99103666 A HK 99103666A HK 1018773 A1 HK1018773 A1 HK 1018773A1
Authority
HK
Hong Kong
Prior art keywords
bis
pct
alkyl
different
same
Prior art date
Application number
HK99103666A
Other languages
English (en)
Inventor
William Alexander Denny
Swarnalatha Akuratiya Gamage
Julie Ann Spicer
Bruce Charles Baguley
Graeme John Finlay
Original Assignee
Xenova Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenova Ltd filed Critical Xenova Ltd
Publication of HK1018773A1 publication Critical patent/HK1018773A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polishing Bodies And Polishing Tools (AREA)
  • Multicomponent Fibers (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Liquid Crystal (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK99103666A 1996-10-18 1999-08-26 Bis(acridinecarboxamide) and bis(phenazinecarboxamide) as antitumour agents HK1018773A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9621795.5A GB9621795D0 (en) 1996-10-18 1996-10-18 Pharmaceutical compounds
PCT/GB1997/002886 WO1998017650A1 (en) 1996-10-18 1997-10-17 Bis(acridinecarboxamide) and bis(phenazinecarboxamide) as antitumour agents

Publications (1)

Publication Number Publication Date
HK1018773A1 true HK1018773A1 (en) 2000-01-07

Family

ID=10801674

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99103666A HK1018773A1 (en) 1996-10-18 1999-08-26 Bis(acridinecarboxamide) and bis(phenazinecarboxamide) as antitumour agents

Country Status (30)

Country Link
US (1) US6114332A (da)
EP (1) EP0934278B1 (da)
JP (1) JP2001503399A (da)
KR (1) KR20000049252A (da)
CN (1) CN1116285C (da)
AT (1) ATE223381T1 (da)
AU (1) AU717724B2 (da)
BG (1) BG64555B1 (da)
BR (1) BR9711948A (da)
CA (1) CA2268411C (da)
CZ (1) CZ295302B6 (da)
DE (1) DE69715230T2 (da)
DK (1) DK0934278T3 (da)
ES (1) ES2183142T3 (da)
GB (2) GB9621795D0 (da)
HK (1) HK1018773A1 (da)
HU (1) HU221953B1 (da)
ID (1) ID22444A (da)
MY (1) MY122017A (da)
NO (1) NO313381B1 (da)
NZ (1) NZ335055A (da)
PL (1) PL193669B1 (da)
PT (1) PT934278E (da)
RO (1) RO120636B1 (da)
RU (1) RU2179972C2 (da)
SK (1) SK285121B6 (da)
TW (1) TW432060B (da)
UA (1) UA67729C2 (da)
WO (1) WO1998017650A1 (da)
ZA (2) ZA979328B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6974878B2 (en) 2001-03-21 2005-12-13 Symyx Technologies, Inc. Catalyst ligands, catalytic metal complexes and processes using same
WO2001019786A1 (en) * 1999-09-10 2001-03-22 Symyx Technologies Catalyst ligands, catalytic metal complexes and processes using and methods of making same
WO2005063760A1 (en) * 2003-12-31 2005-07-14 Council Of Scientific & Industrial Research C-8 LINKED PYRROLO[2,1-c][1,4]BENZODIAZEPINE-ACRIDONE/ACRIDINE HYBRIDS
US9856225B2 (en) * 2013-12-24 2018-01-02 University Of Florida Research Foundation, Incorporated Substituted phenazines as antimicrobial agents
CN104961801B (zh) * 2015-07-13 2018-01-19 兰州大学 一种具有多靶点的抗菌多肽偶联物及其二聚物的合成和应用
CN106554321B (zh) * 2015-09-25 2019-05-28 陆源 一种吩嗪类物质、其制备方法及其应用
KR20230087154A (ko) * 2021-12-09 2023-06-16 한국해양과학기술원 신규 다이페나진 화합물 및 이의 암 또는 신경염증질환 예방 또는 치료 용도

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201084A (en) * 1982-06-25 1985-10-11 New Zealand Dev Finance 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such
EP0172744A2 (en) * 1984-08-16 1986-02-26 Development Finance Corporation Of New Zealand Phenazinecarboxamide compounds
IT1293525B1 (it) * 1997-08-01 1999-03-01 Uni Degli Studi Camerino Bis-acridincarbossiammidi aventi attivita' antitumorale

Also Published As

Publication number Publication date
DE69715230T2 (de) 2009-09-17
PL193669B1 (pl) 2007-03-30
US6114332A (en) 2000-09-05
MY122017A (en) 2006-03-31
NO991833D0 (no) 1999-04-16
NO991833L (no) 1999-06-03
ZA979331B (en) 1998-05-21
KR20000049252A (ko) 2000-07-25
AU717724B2 (en) 2000-03-30
AU4713797A (en) 1998-05-15
WO1998017650A1 (en) 1998-04-30
BG103329A (en) 2000-11-30
RU2179972C2 (ru) 2002-02-27
HU221953B1 (hu) 2003-03-28
CA2268411A1 (en) 1998-04-30
HUP9902883A3 (en) 2001-01-29
CZ295302B6 (cs) 2005-07-13
GB2334032B (en) 2000-11-08
NZ335055A (en) 2000-09-29
DK0934278T3 (da) 2003-01-06
GB9908192D0 (en) 1999-06-02
ATE223381T1 (de) 2002-09-15
PT934278E (pt) 2003-01-31
BR9711948A (pt) 1999-08-24
NO313381B1 (no) 2002-09-23
PL332877A1 (en) 1999-10-25
SK285121B6 (sk) 2006-06-01
RO120636B1 (ro) 2006-05-30
SK50499A3 (en) 2000-05-16
EP0934278B1 (en) 2002-09-04
JP2001503399A (ja) 2001-03-13
CN1116285C (zh) 2003-07-30
CA2268411C (en) 2008-07-22
DE69715230D1 (de) 2002-10-10
ZA979328B (en) 1998-07-06
BG64555B1 (bg) 2005-07-29
GB9621795D0 (en) 1996-12-11
CZ127199A3 (cs) 1999-09-15
EP0934278A1 (en) 1999-08-11
TW432060B (en) 2001-05-01
GB2334032A (en) 1999-08-11
CN1240430A (zh) 2000-01-05
UA67729C2 (uk) 2004-07-15
ES2183142T3 (es) 2003-03-16
ID22444A (id) 1999-10-14

Similar Documents

Publication Publication Date Title
MY100040A (en) Substituted azabicyclo compounds.
MX9504287A (es) Derivados de camptotecina y proceso para su preparacion.
GB2334032B (en) Bis(acridinecarboxamide) and bis(phenazinecarboxamide) as antitumour agents
CA2045857A1 (en) Diaminotrifluoromethylpyridine Derivatives, Process for Their Production and Phospholipase A2 Inhibitor Containing Them
HUP9702393A2 (hu) bisz(2-Halogén-etil)-amino-fenil szubsztituált distamycinszármazékok, tumorellenes és vírusellenes hatóanyagok
HUP0203275A2 (hu) 1-(Gyűrűs amino)-alkilciklohexán-származékok, ezeket tartalmazó görcsoldó hatású gyógyszerkészítmények, valamint ezek alkalmazása
DK0420121T3 (da) Antitumormiddel
DE69523259T2 (de) Amine Derivate, ihre Herstellung und Anwendung
ES2103131T3 (es) Nuevos agentes de nucleosido carbociclico utiles como inhibidores selectivos de citoquinas proinflamatorias.
ES2120498T3 (es) Nuevo compuesto tetraciclico.
KR960702463A (ko) Dc-89 유도체[dc-89 derivative]
NZ291855A (en) Bridged azabicyclo-piperazin-1-yl-2-phenyl-butan-1-one derivatives as 5-ht1a antagonists
HK1060354A1 (en) Variolin derivatives and their use as antitumor agents
MY104048A (en) New allylaminoethylazoles.
TH18165A (th) สารยับยั้งการเกิดคีโมแทกซิของอีโอซีโนฟีล

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20071017